Patents Assigned to INSTITUTE
  • Liposome targeting compounds and related uses
    Patent number: 9326939
    Abstract: The present invention provides liposome targeting compounds for targeting cells expressing sialic acid binding Ig-like lectin (Siglec). The liposome compounds typically comprise a binding moiety that is a glycan ligand of the Siglec on the target cell. The liposome compounds also incorporate or encapsulate a biological agent (e.g., an antigen or a therapeutic agent) that can be delivered to the target cell to modulate or kill the target cell. The invention also provides methods of using the liposome targeting compounds for targeted delivery of antigen and for modulating immune cells or immune responses.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: May 3, 2016
    Assignee: The Scripps Research Institute
    Inventors: James C. Paulson, Weihsu Claire Chen, Norihito Kawasaki, Corwin Nycholat
  • Method of request routing re-direction with loop detection and prevention
    Patent number: 9331976
    Abstract: A method of request routing redirection includes: receiving, by a first content delivery network (CDN) among a plurality of CDNs connected by CDN interconnection (CDNi), a domain name system (DNS) request including a list of CDN-provider-identifications (IDs) of higher CDNs, from a client; determining whether the client's request is processable; and when the client's request is not processable, redirecting the request, while preventing a loop of the request routing on the basis of the list of the CDN-provider-IDs.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: May 3, 2016
    Assignees: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, LG Uplus Corporation, SK TELECOM CO., LTD, Solbox Inc.
    Inventors: Taesang Choi, John Dongho Shinn, Jong Min Lee, Ja-Ryeong Koo
  • Apparatus and method for detecting backlash and slip
    Patent number: 9329144
    Abstract: The detecting apparatus comprises: a monochromator, for Bragg-diffracting the incident beam; an analyzer, on which the beam diffracted by the monochromator is incident, an analyzer Bragg-diffracting the incident beam; a controller, for controlling the driver connected to the monochromator and the analyzer, so as to rotate the analyzer or the monochromator in a first direction and in a second direction opposite to the first direction; and a detector, for detecting the beam diffracted by the analyzer or transmitted through the analyzer while the analyzer or the monochromator is rotating and measuring a backlash and/or a slip of the driver by using the detected beam. The backlash detecting apparatus can measure a backlash and/or a slip in the unit of sub-arcsecond or sub-nanometer by using the radiation beam such as a neutron beam, an X-ray beam or the like.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: May 3, 2016
    Assignee: Korea Institute of Science and Technology
    Inventor: Man-Ho Kim
  • Catalytic conversion of carbohydrates into 5-hydroxymethylfurfural
    Patent number: 9327271
    Abstract: The present invention relates to catalysts and methods for efficient conversion of carbohydrates into 5-hydroxymethylfurfural (HMF), which shows good activity and high selectivity for HMF preparation from saccharides. The catalyst is stable in aqueous system which makes it as an ideal catalyst for HMF production. High HMF yield was obtained even in mild condition. The catalysts of the invention are advantageous in that they are environment-friendly, easy separation and recovery, can be re-used in subsequent reactions, do not corrode reaction reactors. These features make the catalyst as a suitable catalyst for HMF preparation and have strong industrial application significance.
    Type: Grant
    Filed: June 18, 2014
    Date of Patent: May 3, 2016
    Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Qishun Liu, Heng Yin, Yuguang Du, Fengli Yang, Wenxia Wang
  • Method for fabricating flexible display using a shape memory alloy film
    Patent number: 9331126
    Abstract: Provided is a method for fabricating a flexible display device. The method includes attaching a shape memory alloy film memorizing a shape thereof as a curved shape at a shape memory temperature or lower to a flexible substrate at a temperature higher than the shape memory temperature, forming a display device on the flexible substrate, and returning the shape memory alloy to the curved shape to remove the shape memory alloy film from the flexible substrate.
    Type: Grant
    Filed: May 17, 2014
    Date of Patent: May 3, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Sang Seok Lee, Kyoung Ik Cho, Bock Soon Na, Sang Chul Lim, Chan Woo Park, Soon-Won Jung, Jae Bon Koo, Hye Yong Chu
  • Method for producing porous silk fibroin material
    Patent number: 9328135
    Abstract: A method for producing a porous silk fibroin material, containing steps of: freezing a silk fibroin solution containing a silk fibroin aqueous solution having an aliphatic carboxylic acid added thereto; and then melting the frozen solution, thereby providing a porous material. A method for producing a porous silk fibroin material having excellent mechanical characteristics may be provided.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: May 3, 2016
    Assignees: Hitachi Chemical Company, Ltd., National Institute of Agrobiological Sciences
    Inventors: Kazutoshi Kobayashi, Naosuke Sumi, Tsuyoshi Abe, Yasushi Tamada
  • Distributed combined cooling, heating and power generating apparatus and method with internal combustion engine by combining solar energy and alternative fuel
    Patent number: 9328659
    Abstract: The present invention provides a distributed combined cooling, heating and power generating apparatus with an internal combustion engine by combining solar energy and alternative fuel and a method thereof, the apparatus comprising: an energy storage system for combined reaction between solar energy and alternative fuel, a solar fuel internal combustion engine generating system, a lithium bromide refrigeration system for absorbing exhaust heat of flue gas of solar fuel, a reaction device for recovering exhaust heat of flue gas, a heat exchanger for recovering exhaust heat of exhaust gas and a cylinder jacket and water plate heat exchanger.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: May 3, 2016
    Assignee: INSTITUTE OF ENGINEERING THERMOPHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Hongguang Jin, Hui Hong, Qibin Liu, Wei Han, Jun Sui
  • Compositions and methods for promoting hemostasis and other physiological activities
    Patent number: 9327010
    Abstract: Compositions that include nanoscale structured materials or precursors thereof (e.g., self-assembling peptides) are described. The compositions can include other substances (e.g., a vasoconstrictor). Also described are methods for using the compositions to promote hemostasis, to protect the skin or wounds from contamination, to decontaminate a site upon removal of previously applied compositions that provided a protective coating, and to inhibit the movement of bodily substances other than blood. The compositions are also useful in isolating tissue, removing tissue, preserving tissue (for, e.g., subsequent transplantation or reattachment), and as bulking, stabilizing or hydrating agents. Medical devices that include the compositions (e.g., a stent or catheter), bandages or other wound dressings, sutures, and kits that include the compositions are also described.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: May 3, 2016
    Assignees: Massachusetts Institute of Technology, Versitech Limited
    Inventors: Rutledge Ellis-Behnke, Shuguang Zhang, Gerald Schneider, Kwok-Fai So, David Tay, Yu-Xiang Liang
  • Ultrasound transducer and method for making the same
    Patent number: 9327317
    Abstract: The present application provides a multilayer lateral mode coupling method for phased array construction and transducer devices built accordingly. This disclosure describes and demonstrates that the electrical impedance of a phased array can be substantially reduced and readily controlled to be close to the source impedance. The fabrication process is relatively simple and inexpensive. In addition, the elements are robust for use in 1.5, 2, 3 or other dimensional configurations, over an extended period of operation, without structural failure, and providing a high power output required for imaging and/or medical therapy applications.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: May 3, 2016
    Assignee: SUNNYBROOK RESEARCH INSTITUTE
    Inventors: Kullervo Hynynen, Junho Song
  • Mechanically induced trapping of molecular interactions
    Patent number: 9329179
    Abstract: The invention provides devices and methods for surface patterning the substrate of a microfluidic device, and for detection and analysis of interactions between molecules by mechanically trapping a molecular complex while substantially expelling solvent and unbound solute molecules. Examples of molecular complexes include protein-protein complexes and protein-nucleic acid complexes.
    Type: Grant
    Filed: October 6, 2011
    Date of Patent: May 3, 2016
    Assignee: California Institute of Technology
    Inventors: Stephen R. Quake, Sebastian J. Maerkl
  • Magnetic field controlled reconfigurable semiconductor logic device and method for controlling the same
    Patent number: 9331266
    Abstract: A non-volatile reconfigurable logic device executing logical operations and a memory function and controlled by a magnetic field is provided. The reconfigurable logic device includes i) at least one semiconductor device; and ii) a pair of magnetic field controlled devices respectively spaced apart from both sides of the semiconductor device and that are adapted to generate magnetic field leakage to control the semiconductor device. The semiconductor device includes i) a first semiconductor layer; and ii) a second semiconductor layer located on the first semiconductor layer. One of the first semiconductor layer and the second semiconductor layer is a p-type semiconductor layer and the other is an n-type semiconductor layer.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: May 3, 2016
    Assignees: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY
    Inventors: Joon Yeon Chang, Jin Ki Hong, Jin Dong Song, Mark Johnson
  • Recombinant enzyme systems for efficient production of itaconate in cells
    Patent number: 9328362
    Abstract: Described herein is a fusion polypeptide containing an aconitase and a cis-aconitate decarboxylase. Also described are a genetically modified cell expressing the fusion polypeptide and a method of using the cell to produce itaconate.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: May 3, 2016
    Assignee: Industrial Technology Research Institute
    Inventors: Li-Feng Lee, Pei-Ching Chang, Hsiang-Yuan Chu
  • Synthesis gas and nanocarbon production method and production system
    Patent number: 9327970
    Abstract: A synthesis gas and nanocarbon production method has a lower hydrocarbon decomposition step for decomposing lower hydrocarbon to produce hydrogen and nanocarbon, a carbon dioxide reduction step for reacting a part of the nanocarbon produced with carbon dioxide to produce carbon monoxide, and a mixing step for mixing the hydrogen and carbon monoxide produced in a predetermined ratio, thereby nanocarbon and a synthesis gas having a desired gas ratio can be simultaneously produced easily.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: May 3, 2016
    Assignees: THE JAPAN STEEL WORKS, LTD., National Univeristy Corporation Kitami Institute of Technology
    Inventors: Satoru Nakamura, Akio Tada
  • Asymmetric liposomes for the highly efficient encapsulation of nucleic acids and hydrophilic anionic compounds, and method for preparing same
    Patent number: 9326940
    Abstract: The present invention relates to asymmetric liposomes for high encapsulation efficiency of nucleic acids and hydrophilic anionic compounds, and to a method for preparing same, and specifically, to asymmetric liposomes consisting of a cationic lipid having a small head group as an internal lipid and a neutral or PEGylated lipid having a big head group as an external lipid, wherein nucleic acids and/or anionic compounds are encapsulated in the internal lipid. According to the present invention, asymmetric liposomes, in which nucleic acids and hydrophilic anionic compounds are encapsulated with high efficiency, may be prepared, and thus the same may be used for various purposes, such as gene therapy, and the delivery of hydrophilic anionic drugs which are difficult to prepare as prodrugs, and drug delivery, imaging, etc. can be carried out by encapsulating a fluorescent contrast agent in the liposome.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: May 3, 2016
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Myung Kyu Lee, Abbas Mokhtarieh Amir, Bong Hyun Chung, Jong Min Choi
  • Solar cell module and method of manufacturing the same
    Patent number: 9331218
    Abstract: Provided are a solar cell module and a method of manufacturing the same. The solar cell module including: a substrate; a bottom electrode layer discontinuously formed on the substrate; a light absorbing layer formed on the bottom electrode layer and including a first trench that exposes the bottom electrode layer; and a transparent electrode layer extending from the top of the light absorbing layer to the bottom electrode layer at the bottom of the first trench, and including a first oxide layer, a metal layer, and a second oxide layer, all of which are staked on the light absorbing layer and the bottom electrode layer.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: May 3, 2016
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Woo-Seok Cheong, Rae-Man Park
  • Semiconductor devices with a gate conductor formed as a spacer, and methods for manufacturing the same
    Patent number: 9331182
    Abstract: Semiconductor devices and methods for manufacturing the same are disclosed. In one aspect, the method comprises forming a first shielding layer on a substrate, and forming one of source and drain regions with the first shielding layer as a mask. Then, forming a second shielding layer on the substrate, and forming the other of the source and drain regions with the second shielding layer as a mask. Then, removing a portion of the second shielding layer which is next to the other of the source and drain regions. Lastly, forming a first gate dielectric layer, a floating gate layer, and a second gate dielectric layer, and forming a gate conductor as a spacer on a sidewall of a remaining portion of the second shielding layer.
    Type: Grant
    Filed: January 9, 2014
    Date of Patent: May 3, 2016
    Assignee: Institute of Microelectronics, Chinese Academy of Sciences
    Inventors: Huilong Zhu, Qingqing Liang, Huicai Zhong
  • Integrated antenna package and manufacturing method thereof
    Patent number: 9331030
    Abstract: An integrated antenna package including a laminated structure and a multi-layered substrate is provided. The laminated structure includes at least a chip embedded therein and at least a plated through-hole structure penetrating the laminated structure. The multi-layered substrate is stacked on the laminated structure. The multi-layered substrate includes at least a metal layer located on one side of the multi-layered substrate away from the laminated structure and the metal layer includes at least an antenna pattern located above the chip. The multi-layered substrate includes at least a plated via and through-hole structure penetrating the multi-layered substrate and electrically connected to the chip, so that the antenna pattern is electrically connect with the chip. Also, the manufacturing method of the integrated antenna package is provided.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: May 3, 2016
    Assignee: Industrial Technology Research Institute
    Inventors: Cheng-Hua Tsai, Shyh-Jong Chung
  • Device for extracting, storing and/or processing blood or other substances of human or animal origin, and for applying blood compounds or other biological compounds
    Patent number: 9326914
    Abstract: Device (1a, 1b, 1c, 1d; 40) for extracting, storing and/or processing blood or other substances of human or animal origin, and for applying blood compounds or other biological compounds, which comprises a body (2; 41) inside which a piston (3; 42) is capable of moving longitudinally and is separable at least in part, where the body (2; 41) is provided with an internal space (9; 51) that may be connected to the outside by means of a conduit (6; 50) at a first end (4; 48) of the body (2; 41), where the body (2; 41) and the piston (3; 43) may be blocked longitudinally in at least one position to allow the creation of different degrees of vacuum. The device has multiple uses and is extremely versatile.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: May 3, 2016
    Assignee: BIOTECHNOLOGY INSTITUTE, I MAS D, S.L.
    Inventor: Eduardo Anitua Aldecoa
  • Multi-channel through-wall communication system using crosstalk suppression
    Patent number: 9331879
    Abstract: A system for communicating through a solid wall uses piezoelectric transducers in a multiple-input multiple-output configuration and applies crosstalk suppression. Methods of suppressing or avoiding crosstalk between parallel communication channels includes zero-forcing, eigenmode transmission, and least mean squared error processing. Orthogonal frequency division multiplexing can be used to increase transmission rates using many subchannels. Bit-loading can be used to maximize system performance.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: May 3, 2016
    Assignee: Rensselaer Polytechnic Institute
    Inventors: Gary J. Saulnier, Jonathan D. Ashdown, Tristan J. Lawry, Kyle R. Wilt, Henry A. Scarton
  • Nanoparticles, method of manufacturing nanoparticles, and electronics device including the same
    Patent number: 9331283
    Abstract: The method of manufacturing nanoparticles of a target material includes mixing graphene oxide with an aqueous solvent to prepare an aqueous solution, mixing the target material with an organic solvent to prepare an organic solution, mixing the aqueous solution with the organic solution, and preparing nanoparticles of the target material by the graphene oxide.
    Type: Grant
    Filed: July 22, 2013
    Date of Patent: May 3, 2016
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jung Ah Lim, Yong-Won Song, Jae-Min Hong, Dong Youn Yoo, Hee-Suk Kim