Abstract: The invention features compositions and methods for treating or preventing a neoplasia. More specifically, the invention provides compositions and methods for disrupting the interaction of a BET family polypeptide comprising a bromodomain with chromatin (e.g., disrupting a bromodomain interaction with an acetyl-lysine modification present on a histone N-terminal tail).

Abstract: A self-healing monolithic integrated includes an electronic circuit having a plurality of transistors. At least one sensor is disposed within and electrically coupled to the electronic circuit and configured to sense a performance metric of the electronic circuit. A plurality of actuators is disposed within the circuit. Each actuator of the plurality of actuators has electrically coupled to it a control terminal. The plurality of actuators is configured to perform a selected one of, electrically coupling at least one transistor of the plurality of transistors into the electronic circuit and electrically de-coupling at least one transistor of the plurality of transistors, in response to operation of one of the control terminals to improve the performance metric.

Abstract: A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of content are provided. The metadata may include a minBufferTime attribute indicating a minimum amount of initially buffered media content. A terminal may receive content from a server before playback of the content, and may buffer the content by at least the minimum amount. The metadata may include a range attribute that designates a range of a target indicated by a Uniform Resource Locator (URL). The terminal may receive bytes designated by the range attribute from the URL, and may play back the content using the received bytes.

Abstract: A method for manufacturing a MOSFET, including: performing ion implantation, via a shallow trench surrounding an active region in a semiconductor substrate, into a first sidewall of the active region and into a second sidewall of the active region opposite to the first sidewall to form a first heavily doped region in the first sidewall and a second heavily doped region in the second sidewall; filling the shallow trench with an insulating material, to form a shallow trench isolation; forming a gate stack and an insulating layer on the substrate, wherein the insulating layer surrounds and caps the gate stack; forming openings in the substrate using the shallow trench isolation, the first and second heavily doped regions, and the insulating layer as a hard mask; and epitaxially growing a semiconductor layer with a bottom surface and sidewalls of each of the openings as a seed layer.

Abstract: A particle manipulation system and a projection device are provided. The projection device includes an image source and a projection lens. The image source provides an image beam. The projection lens is disposed on a light path of the image beam and includes a zoom lens set and a focusing lens set. The zoom lens set is disposed on the light path of the image beam from the image source and includes at least two lens groups disposed in sequence on the light path of the image beam. The focusing lens set is disposed on the light path of the image beam. The zoom lens set is disposed between the image source and the focusing lens set. A photoconductor chip is disposed on the light path of the image beam from the projection lens.

Abstract: The present invention relates to methods for modulating angiogenesis, comprising administering to a subject, or cells or tissue derived therefrom: (i) one or more miRNA, or precursors or variants thereof, wherein at least one of said miRNA comprises a seed region comprising the sequence UCACAGU (SEQ ID NO:37) to inhibit angiogenesis; or (ii) one or more antagonists of a miRNA, wherein said miRNA comprises a seed region comprising the sequence UCACAGU (SEQ ID NO:37) to promote or induce angiogenesis. Also provided are methods of diagnosis of conditions associated with abnormal angiogenesis, or determining predisposition thereto. Suitable pharmaceutical compositions are also provided.

Abstract: Systems and methods for determining a safety level of a network vulnerable to attack from at least one origin to at least one target are described. Machines, components, and vulnerabilities in a network may be associated to one another. Degrees of similarity among the vulnerabilities may be determined and subsets of vulnerabilities may be grouped based on their determined degrees of similarity to one another. This data may be used to generate an attack graph describing exploitation of vulnerabilities and grouped vulnerabilities and defining vulnerability exploit condition relationships between at least one origin and at least one target. The attack graph may be analyzed using a k-zero day metric function to determine a safety level.

Abstract: Provided are a superconducting accelerometer, an acceleration measurement device, and an acceleration measurement method. The superconducting accelerometer includes a test mass including a rod-shaped body part, a disc-shaped coupling part connected to the body part, the test mass being made of a superconductor; a solenoid levitation coil disposed to surround a portion of the body part and adapted to magnetically levitate the test mass, the solenoid levitation coil being made of a superconductor; a measurement superconductor coil disposed at at least one side of an upper portion and a lower portion of the coupling part; and a SQUID sensor adapted to detect current depending on variation of a distance between the test mass and the measurement superconductor coil.

Abstract: Provided is a motor driving circuit which transmits a driving signal to a motor, including a gate driver generating the driving signal corresponding to a pulse width modulation signal, a pulse width modulation signal generator generating the pulse width modulation signal according to Hall sensor signals received from Hall sensors mounted in the motor, a current sensor measuring a link current provided to the gate driver, a low pass filter outputting a filter current that high frequency components are removed from the measured link current, and a minimum power consumption estimating unit generating a lead angle according to a start signal with reference to the filter current, wherein the pulse with modulating signal is changed according to the lead angle.

Abstract: A copolymer of DCPD-containing benzoxazine (DCPDBz) and cyanate ester resin forms a low-dielectric thermosetting polymeric material for making electronic components. A method of manufacturing the copolymer is also introduced. The method includes allowing DCPD-phenol oligomer, aniline, and paraformaldehyde to react at 110° C. for 6-12 hours before being extracted and baked to obtain DCPDBz; and mixing cyanate ester and the DCPDBz at 150° C.; heating the mixture up to 220° C.

Abstract: An impedance analyzing device, adapted to a testee comprising an electrode or at least one battery cell, includes a signal capturing unit, a signal adjusting unit, a signal analyzing unit, a processing unit, and a power source supply unit providing a variable-frequency voltage signal to the testee. The signal adjusting unit receiving and adjusts a variable-frequency voltage signal and the current signal to generate an adjusted variable-frequency voltage signal and an adjusted current signal. The signal capturing unit captures a current signal generated by the testee in response to the variable-frequency voltage signal. The signal analyzing unit receives and analyzes the adjusted variable-frequency voltage signal and the adjusted current signal in frequency domain to obtain a frequency domain parameter and/or a time domain parameter. The processing unit receives the frequency domain parameter and/or the time domain parameter to obtain an impedance variation characteristic of the testee.

Abstract: A method for preparing a carbon microparticle from an organic raw material having lignin as a main constituent, wherein an aqueous solution with 5% total concentration of lignin and sodium hydroxide (the proportion in mass is 1:0.5) is spray-dried to prepare a complex microparticle. This complex microparticle is heat-processed under nitrogen atmosphere at 600° C. for one hour and cooled. Thereafter, this is washed with water and further dried to prepare a hollow carbon microparticle such as those shown in FIG. 2 (b). The prepared carbon microparticle is light-weight and has an equivalent specific surface area to commercially available activated charcoal.

Abstract: The present invention is a superconducting partial insulation magnet and a method for providing the same. The magnet includes a coil with a non-insulated superconducting wire winding wound around a bobbin. The coil has a first wire layer, a second wire layer substantially surrounding the first layer, and a first layer of insulating material disposed between the first wire layer and the second wire layer. Each wire layer comprises a plurality of turns, and the first layer of insulating material substantially insulates the second wire layer from the first wire layer.

Abstract: A novel gas separation membrane having excellent gas permeability and gas separation performance, particularly carbon dioxide (CO2) permeability and excellent separation performance of carbon dioxide to methane (CH4) is provided. Moreover, a novel gas separation membrane having excellent heat resistance, chemical resistance and strength etc. is preferably provided. A gas separation membrane comprising a resin comprising a branched polybenzoxazole has excellent gas permeability and gas separation performance, particularly excellent carbon dioxide (CO2) permeability and excellent separation performance of carbon dioxide to methane (CH4). The resin comprising a branched polybenzoxazole preferably has a cross-linked structure. Furthermore, the resin comprising a branched polybenzoxazole is preferably a hybrid with silica.

Abstract: Provided is a coring apparatus for collecting marine sediments, and more particularly, to a coring apparatus having a core filled with marine sediments when the coring apparatus is inserted into a seabed.

Abstract: Disclosed are an apparatus and a method for sensing pressure using an optical waveguide sensor. The apparatus for sensing pressure using an optical waveguide sensor, includes: a light source radiating light; an optical waveguide panel emitting some of the radiated light outside through a plurality of light transmitting regions previously formed, and changing an amount of totally reflected light according to pressure applied to at least one of the plurality of light transmitting regions; a detector detecting the amount of light; and an analyzer determining intensity and a location of the pressure according to the detected amount of light.

Abstract: Power flow controllers based on Imputed DC Link (IDCL) cells are provided. The IDCL cell is a self-contained power electronic building block (PEBB). The IDCL cell may be stacked in series and parallel to achieve power flow control at higher voltage and current levels. Each IDCL cell may comprise a gate drive, a voltage sharing module, and a thermal management component in order to facilitate easy integration of the cell into a variety of applications. By providing direct AC conversion, the IDCL cell based AC/AC converters reduce device count, eliminate the use of electrolytic capacitors that have life and reliability issues, and improve system efficiency compared with similarly rated back-to-back inverter system.

Abstract: A method for representing a terrain, a method for creating terrain primitives, and an apparatus using the methods are disclosed. The terrain representation method includes: reading digital elevation model (DEM) data of a terrain; extracting feature points of the terrain from the DEM data of the terrain; creating a plurality of terrain primitives according to the feature points of the terrain; storing terrain representation model data based on the plurality of terrain primitives; and converting the terrain primitive based terrain representation model data into DEM data, and visualizing the DEM data.

Abstract: A lithography pupil shaping optical system and method for generating off-axis illumination mode. The invention is composed of illumination mode generation unit, rotatable wave plate, polarization beam splitter unit, ring I generation unit and ring II generation unit. Through selecting corresponding diffractive optical element and appropriate adjustment, this invention can generate various illumination modes including single ring illumination mode and double ring illumination mode. The intensity at pupil plane and the inner and outer diameters of the off-axis illumination mode can be adjusted continuously.

Abstract: A buffer and output method and a buffer module for a multimedia stream are provided, wherein multimedia stream packets are received and stored into a first buffer, and when an actual remaining time calculated according to an accumulated idle time and a buffer time, is greater than a remaining time threshold value, following steps are performed. A first present time is read, and a sleep instruction is executed, so as to wait for a preset idle time. A second present time is read, and an actual idle time different from the preset idle time is calculated according to the first present time and the second present time. A part of buffer units are enabled according to the accumulated idle time accumulated according to the actual idle time, to output the stored multimedia stream packets to a second buffer of a player.