Patents Assigned to INSTITUTE
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Patent number: 9270381Abstract: Disclosed are a method and an apparatus for transmitting and receiving coherent optical OFDM.Type: GrantFiled: November 22, 2011Date of Patent: February 23, 2016Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Chun Ju Youn, Yong-Hwan Kwon, Duk Jun Kim, Jong-Hoi Kim, Joong-Seon Choe, Kwang-Seong Choi, Eun Soo Nam
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Patent number: 9266822Abstract: Novel solid forms of tacedinaline (4-(acetylamino)-N-(2-aminophenyl)benzamide), including crystalline tacedinaline Form B, a novel crystalline tacedinaline TFA salt, and amorphous tacedinaline, are disclosed. Pharmaceutical compositions comprising crystalline tacedinaline Form B, the novel crystalline tacedinaline TFA salt, and/or amorphous tacedinaline, and methods of treating various conditions by administering those novel solid forms, are also disclosed.Type: GrantFiled: March 14, 2014Date of Patent: February 23, 2016Assignee: THE BROAD INSTITUTE, INC.Inventors: Edward Holson, Florence F. Wagner, G. Patrick Stahly
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Patent number: 9270895Abstract: When imaging bright objects, a conventional detector array can saturate, making it difficult to produce an image with a dynamic range that equals the scene's dynamic range. Conversely, a digital focal plane array (DFPA) with one or more m-bit counters can produce an image whose dynamic range is greater than the native dynamic range. In one example, the DFPA acquires a first image over a relatively brief integration period at a relatively low gain setting. The DFPA then acquires a second image over longer integration period and/or a higher gain setting. During this second integration period, counters may roll over, possibly several times, to capture a residue modulus m of the number of counts (as opposed to the actual number of counts). A processor in or coupled to the DFPA generates a high-dynamic range image based on the first image and the residues modulus m.Type: GrantFiled: April 25, 2014Date of Patent: February 23, 2016Assignee: Massachusetts Institute of TechnologyInventors: Michael W. Kelly, Megan H. Blackwell, Curtis B. Colonero, James Wey, Christopher David, Justin Baker, Joseph Costa
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Patent number: 9268051Abstract: Provided are a system for acquiring chirp data for profiling the shallow sedimentary layers and a method for acquiring chirp data using the same, and more particularly, a system for acquiring chirp data which includes a new apparatus capable of recording chirp raw data and manufactures a high-resolution raw section preserving polarity and phase information using the recorded chirp raw data to enhance continuity and resolution of the sedimentary layers and a method for acquiring chirp data using the same.Type: GrantFiled: July 25, 2014Date of Patent: February 23, 2016Assignee: Korea Institute of Geoscience and Mineral ResourcesInventors: Young Jun Kim, Nam Hyung Koo, Snons Cheong, Jong Hwa Chun, Dong Keun Yoo
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Patent number: 9268025Abstract: An offset estimator (e.g., a time delay, a spatial image offset, etc.) makes use of a transform approach (e.g., using Fast Fourier Transforms). The sparse nature of a cross-correlation is exploited by limiting the computation required in either or both of the forward and inverse transforms. For example, only a subset of the transform values (e.g., a regular subsampling of the values) is used. In some examples, an inverse transform yields a time aliased version of the cross-correlation. Further processing then identifies the most likely offset of the original signals by considering offsets that are consistent with the aliased output.Type: GrantFiled: August 9, 2012Date of Patent: February 23, 2016Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Haitham Zuhair Al-Hassanieh, Fadel Adib, Dina Katabi, Piotr Indyk
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Patent number: 9267937Abstract: Screening of a library of particles in vivo and/or in vitro using Polyplex Iterative Combinatorial Optimization (PICO) allows for the design of particles for targeting a specific organ, tissue (e.g., cancer), or cell. Particles may, for example, include different targeting agents (e.g., aptamers or plurality of aptamers) on their surfaces, and the aptamer or aptamers may be evolved to provide better targeting of the particles. Libraries of particles are enriched in characteristics of particles that have been found to migrate to a tissue of interest, be taken up by cells, etc. The process may be repeated to engineer particles of a desired specificity or biological function.Type: GrantFiled: December 15, 2006Date of Patent: February 23, 2016Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.Inventors: Omid C. Farokhzad, Aleksandar Filip Radovic-Moreno, Robert S. Langer
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Patent number: 9266983Abstract: The present disclosure provides a catalyst composition for ethylene oligomerization including an imino ferrous complex shown in Formula (I) as the main catalyst, an aluminum-containing cocatalyst, water, and an organic solvent: According to the present disclosure, a higher oligomerization activity can be obtained with the catalyst composition than with a catalyst composition system in the prior art which contains no water. Moreover, when the catalyst composition according to the present disclosure is used, a high selectivity of ?-olefins is obtainable. Besides, the catalyst composition according to the present disclosure can enable rapid initiation, stable operation, and good repeatability of the oligomerization reaction. According to the present disclosure, a high oligomerization activity can be obtained even at a rather low ratio of Al/Fe, or at a low reaction temperature.Type: GrantFiled: April 16, 2014Date of Patent: February 23, 2016Assignees: CHINA PETROLEUM & CHEMICAL CORPORATION, BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATIONInventors: Tonglin Li, Mingfang Zheng, Jun Liu, Huaijie Wang, Haiying Zhang, Weizhen Li, Jilong Wang, Yuling Piao
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Patent number: 9269954Abstract: The present invention is one which provides a production process for lithium-silicate-system compound, the production process being characterized in that: a lithium-silicate compound being expressed by Li2SiO3 is reacted with a substance including at least one member of transition-metal elements that is selected from the group consisting of iron and manganese at 400-650° C. in a molten salt of a carbonate mixture comprising lithium carbonate and at least one member of alkali-metal carbonates that is selected from the group consisting of potassium carbonate, sodium carbonate, rubidium carbonate and cesium carbonate in a mixed-gas atmosphere including carbon dioxide and a reducing gas; and a positive-electrode active material for lithium-ion secondary battery that comprises a lithium-silicate-system compound being obtained by the aforesaid process.Type: GrantFiled: November 20, 2009Date of Patent: February 23, 2016Assignees: NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY, KABUSHIKI KAISHA TOYOTA JIDOSHOKKIInventors: Toshikatsu Kojima, Tetsuo Sakai, Takuhiro Miyuki, Yasue Okuyama, Akira Kojima, Junichi Niwa, Hitotoshi Murase
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Patent number: 9268032Abstract: A sensing element for electromagnetic wave detection, electrical radiography imaging system applying the element and method thereof is provided. The sensing element may include a substrate, an active component on the substrate, a plurality of first electrodes on the substrate, a plurality of second electrodes on the substrate, a first blocking layer, a photo-conversion layer on the first blocking layer, and a third electrode on the photo-conversion layer. The plurality of first electrodes is coupled together. The plurality of first electrodes is interlaced with the plurality of second electrodes and is coupled together. The first blocking layer is on the active component, the plurality of first electrodes, and the plurality of second electrodes. The photo-conversion layer is for absorbing electromagnetic wave transmitted through an object being imaged by a radiography imaging system and generates electric charges collected by the plurality of first and second electrodes, and the third electrodes.Type: GrantFiled: December 3, 2014Date of Patent: February 23, 2016Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Ming-Huan Yang, Bo-Wen Xiao, Chien-Ju Lee, Wen-Tung Wang, Wei-Ben Wang
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Patent number: 9265747Abstract: The present invention provides compositions, preparations, formulations, kits, and methods useful for treating subjects in need of therapeutic protocol, including subjects having cancer or at risk of developing cancer. Some embodiments of the invention may comprise a composition comprising a first component comprising a precursor to a therapeutically active platinum agent and a precursor to a second therapeutically active agent. The therapeutically active platinum agent and the second therapeutically active agent may dissociate from each other, thereby forming a first therapeutically active platinum agent and a second therapeutically active agent. The second therapeutically active gent may affect a cellular pathway of a cancer cell and may be substantially inactive towards non-cancerous cells.Type: GrantFiled: August 26, 2009Date of Patent: February 23, 2016Assignee: Massachusetts Institute of TechnologyInventors: Stephen J. Lippard, Shanta Dhar
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Patent number: 9266872Abstract: The present invention relates to a 2-hydroxyarylamide derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The 2-hydroxyarylamide derivative prepared by the present invention is excellent in the inhibition of the activity of TMPRSS4 serine protease and the suppression of the infiltration of TMPRSS4-expressed cancer cells, and thus can be useful as a composition for preventing or treating cancer by inhibiting TMPRSS4 over-expressed in cancer cells, particularly, colorectal cancer, lung cancer, breast cancer, prostate cancer, ovarian cancer, pancreatic cancer, or stomach cancer cells.Type: GrantFiled: April 18, 2014Date of Patent: February 23, 2016Assignee: Korea Research Institute of Bioscience and BiotechnologyInventors: Semi Kim, Ill Young Lee, Hye-Jin Min, Eun-Hee Nam, Pilho Kim, Chang Soo Yun, Dong Joon Ko
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Patent number: 9269144Abstract: Images of an object, such as OCT scans of a human eye, can include distortions and data gaps due to relative motion of the object and the image acquisition device. Methods and systems for correction of such distortions and data gaps are described herein. Motion-corrected data is arrived at by applying three-dimensional transforms to input three-dimensional data sets that represent at least partially overlapping regions of the imaged object. The three dimensional transforms are computed based on an objective function that accounts for similarity between the transformed three-dimensional data sets and the estimated motion of the object relative to an imaging instrument. Methods and systems described herein advantageously eliminate the need for postulated assumptions and reliance on landmarks and are capable of filling data gaps, thereby producing high quality, undistorted images of objects subject to movement during imaging.Type: GrantFiled: April 29, 2011Date of Patent: February 23, 2016Assignees: Friedrich-Alexander-Universitaet Erlangen-Nuernberg, Massachusetts Institute of TechnologyInventors: Martin F. G. Kraus, Benjamin M. Potsaid, James G. Fujimoto, Markus Anton Mayer, Ruediger Bock, Joachim Hornegger
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Patent number: 9270990Abstract: Provided are a method and apparatus for encoding and decoding images based on constrained offset compensation and a loop filter. The image decoding apparatus: receives, from an encoder, a first indicator indicating whether a sequence, a picture, a frame, a slice, a coding unit (CU), a prediction unit (PU), and/or a transform unit (TU) supports constrained offset compensation; receives, from the encoder, a second indicator indicating whether constrained sample adaptive offset (SAO) compensation or an adaptive loop filter (ALF) is applied; receives a parameter from the encoder; and applies the SAO compensation or the ALF to pixels of a restored image on the basis of the second indicator and the parameter.Type: GrantFiled: September 27, 2012Date of Patent: February 23, 2016Assignee: Electronics and Telecommunications Research InstituteInventors: Jin Ho Lee, Hui Yong Kim, Sung Chang Lim, Jin Soo Choi, Jin Woong Kim
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Patent number: 9270502Abstract: Embodiments provide a digital RF receiver including a signal converting unit which converts an RF signal received from an external device into a digital signal, a plurality of functional modules which processes the digital signal in accordance with a predetermined algorithm when the digital signal is input, and a signal processing controller which selects at least one of the plurality of functional modules to control the digital signal to be processed in consideration of whether an IF signal component is included in the digital signal or a sampling rate related with sampling information of the digital signal.Type: GrantFiled: August 6, 2013Date of Patent: February 23, 2016Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTEInventors: Ik Soo Eo, Sang Kyun Kim, Seon Ho Han
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Patent number: 9266875Abstract: Provided are a compound represented by Formula I, a pharmaceutically acceptable salt thereof, or a solvate thereof; and a pharmaceutical composition for cancer treatment and a pharmaceutical composition for a radiation sensitizer for cancer treatment, each pharmaceutical composition including the compound of Formula I, the pharmaceutically acceptable salt thereof, or the solvate thereof: wherein, in Formula I, —R1 is a C1-C3 alkoxy, ?O, or —OH, and —R2 is a 5- or 6-membered heteroaryl including 1 to 2 hetero atoms selected from nitrogen and oxygen, wherein a carbon of the 5- or 6-memberedheteroaryl is optionally substituted with a C1-C3 alkyl a C1-C3 alkoxy, or hydroxy.Type: GrantFiled: July 18, 2014Date of Patent: February 23, 2016Assignee: Korea Institute of Radiological & Medical SciencesInventors: Sung Hee Hong, In Seok Hong, Kee Ho Lee
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Patent number: 9269908Abstract: The present invention provides a bipolar compound represented by formula (I) and the derivatives thereof as a host material having excellent bipolar transporting properties for organic light-emitting diodes (OLEDs). The present invention also relates to a device including at least a layer of the bipolar compound and/or the derivatives thereof as a host material and a method of making the same.Type: GrantFiled: April 19, 2012Date of Patent: February 23, 2016Assignee: NANO AND ADVANCED MATERIALS INSTITUTE LIMITEDInventors: Chun Sing Lee, Xiao Hong Zhang, Shuit Tong Lee, Caijun Zheng, Man Keung Fung
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Patent number: 9265787Abstract: Methods for treating tumors comprising cells expressing the vitamin D receptor are provided, and comprise inhibiting the expression or the biologic activity of the vitamin D receptor in the tumor cells, and/or inhibiting the expression or the biologic activity of a constituent of the vitamin D receptor signaling pathway in the tumor cells, and administering to the tumor cells an effective amount of gemcitabine.Type: GrantFiled: December 26, 2013Date of Patent: February 23, 2016Assignee: Institute for Cancer ResearchInventors: Timothy J. Yen, Vikram Bhattacharjee
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Patent number: 9267786Abstract: An apparatus and method for adjusting prism beam expander. The prism beam expander adjustment apparatus has a light source, a baseplate, a precise rotary stage, support columns, a two-dimensional slide stage, the first 90-degree bellcrank lever, an indication light source, the second 90-degree bellcrank lever, an optical filter, a photodetector, a computer, and an assembly platform. Incidence angles of all prisms of a prism beam expander can be precisely demarcated and designed beam magnification is obtained with the preferred adjustment methods. The parallel of the prisms can be guaranteed by monitoring the pitching of the prisms in the adjustment process. As a result, the linewidth narrowing and cavity losses decreasing can be improved by application of the fixed prism beam expander.Type: GrantFiled: November 28, 2014Date of Patent: February 23, 2016Assignee: Shanghai Institute of Optics And Fine Mechanics, Chinese Academy of SciencesInventors: Haibo Zhang, Zhijun Yuan, Jun Zhou, Yunrong Wei, Liyuan Jiang, Liming Geng
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Patent number: 9266080Abstract: Disclosed is a reaction device for producing hydrocarbons from synthesis gas, in which hydrocarbons, olefins, oxygenates, etc., are produced over a Fischer-Tropsch catalyst by using synthesis gas, so that the catalyst particles can easily be from a slurry which is discharged to the outside. That is, the present invention provides a reaction device for producing hydrocarbons from synthesis gas, in which an internal filter system for separating particles enlarged due to agglomeration phenomenon of a catalyst is installed inside the reactor, and a separating device is separately disposed outside, such that it is possible to recirculate only particles having a size appropriate for performing F-T synthesis in the slurry phase, and additionally, it is possible to effectively discharge and process a catalyst aggregated due to a combination of fine catalyst particles, the catalyst chipped off during the operation, etc., liquid hydrocarbon, resulting water, etc., in the slurry phase reactor.Type: GrantFiled: July 19, 2011Date of Patent: February 23, 2016Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGYInventors: Kyoung Su Ha, Du Eil Kim, Gyu In Jung, Jong Wook Bae, Ki Won Jun
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Patent number: 9267005Abstract: Disclosed is a flexible maleimide polymer. The flexible maleimide polymer includes a reaction product of reactants (a)-(c). The reactant (a) is maleimide, a compound with a structure represented by Formula (I), a compound with a structure represented by Formula (II), or combinations thereof wherein R1 is —(CH2)10—CO2H, and R2 is H, OH, SO3Na, NO2, CN or CO2H. The reactant (b) is a compound with a structure represented by formula (III) wherein A is R3 is H or methyl group, x is between 1-12, R4 is H or methyl group, and y and z are both between 1-5. The reactant (c) is a compound with a structure represented by formula (IV), or a compound with a structure represented by formula (V) wherein R5 and R6 are independent H or C1-4 alkyl group.Type: GrantFiled: July 16, 2012Date of Patent: February 23, 2016Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTEInventors: Li-Fu Huang, Li-Duan Tsai, Wei-Hsin Wu