Abstract: The present invention relates to novel compounds which are able to modulate b-raf kinases, and the use of such compounds in the treatment of various diseases, disorders or conditions.

Abstract: Disclosed herein is a test apparatus for early landslide detection fully-connected with pore water pressure, surface displacement and shear surface. The test apparatus calculates a factor of safety of a slope based on variation in pore water pressure, surface displacement and shear surface of a soil mass, and predicts a change in factor of safety, thus making early landslide detection possible. In the test apparatus, while a container of a slider is moved with a soil mass loaded into the container, shear surface and surface displacement environment is provided, and the shear strength and the shear stress of the soil mass can be calculated based on the pore water pressure and the weight of the soil mass. Thereby, the factor of safety of the soil mass can be calculated, and early landslide detection can be realized by using variation of the factor of safety of the slope.

Abstract: Described herein are compounds and compositions for the amelioration of arthritis or joint injuries by inducing mesenchymal stem cells into chondrocytes.

Abstract: The present invention provides an organic thin film and an organic transistor having high performance stability and mobility. Specifically, there are provided an organic thin film including a compound containing a charge transporting molecular unit A having a structure of an aromatic fused ring system and a unit B serving as a side chain, the compound having a bilayer structure; an organic semiconductor device including the organic thin film; and an organic transistor including the organic thin film used as an organic semiconductor layer.

Abstract: The method includes, receiving a content request message from a user terminal, comparing a batching window value and a timer value in session information when there is session information corresponding to received content, and transmitting a content response message including an address of a stored surrogate server to the user terminal when the timer value is less than the batching window value. In addition, the method includes, receiving a request message for requesting the same content from another user terminal, and transmitting the content response message including address information of the same surrogate server to another user terminal when the timer value is less than the batching window value. Therefore, since more channels can be assigned to one surrogate server, it is possible to decrease data transmission costs of the surrogate server.

Abstract: A signaling method for a terminal that performs direct communication between terminals terminal is disclosed. A transmitting terminal transmits a link establishment request message for establishing a link to a receiving terminal, and the receiving terminal transmits a link establishment response message responding to this message to the transmitting terminal. The link establishment request message includes a field indicating a flow to use if the receiving terminal acquires a token.

Abstract: Provided are an apparatus and method for sharing vehicle information among autonomous vehicles. According to the apparatus and method, not only current driving-related information and future driving-related information of a self vehicle but also current driving-related information and future driving-related information of another vehicle is acquired and used to control travel of the self vehicle. Accordingly, the safety of travel is improved, and efficient autonomous travel is enabled.

Abstract: The present invention relates to a process for the preparation of a silicate compound, comprising (1) providing at least one layered silicate; and (2) mixing said layered silicate with water and at least one silicon containing compound according to formula R4-mSi[—(SiR2)n—R]m wherein at least one residue R is a leaving group and none of the residues R contains Si; m is 0, 1, 2, 3, or 4; and n is an integer greater than or equal to 0.

Abstract: An optical transmission apparatus includes: a transmission light source configured to generate single-mode light of a specific wavelength; a power coupler configured to split the light generated by the transmission light source into a plurality of light sections; at least one modulator configured to modulate an electrical signal carrying different data into at least one optical signal using the light section from the power coupler; and a mode multiplexer configured to convert the modulated optical signal into a different mode, and to transmit the mode-converted optical signal to a fiber.

Abstract: An apparatus for fabricating three-dimensional nonwoven fabric structure is disclosed, which includes an adjustable frame, a three-dimensional mold, a rotary shaft connecting the three-dimensional mold and the adjustable frame, and a meltblown device. The three-dimensional mold is rotated relative to the adjustable frame. The meltblown device has plural nozzles for spinning a plurality of fibers, wherein the three-dimensional mold is rotated in front of the nozzles to select the fibers, and a three-dimensional nonwoven fabric structure is formed on the three-dimensional mold.

Abstract: A transistor includes source/drain electrodes provided on a substrate; a semiconductor oxide layer provided between the source/drain electrodes; a gate electrode facing the semiconductor oxide layer; and a gate insulating layer interposed between the semiconductor oxide layer and the gate electrode, wherein the semiconductor oxide layer has a nano-layered structure including at least one first nano layer comprised of a first material and at least one second nano layer comprised of a second material that are alternatingly stacked one on another to provide at least one interface, and wherein the first material and the second material are different materials that are effective to form an electron transfer channel layer at the interface.

Abstract: The present invention relates to an apparatus and method that control a vessel deviating from an anchorage using wide-range sensor-based spherical trigonometry. In the method, vessels anchored in an anchorage are monitored. The anchorage is defined as a group, and the group of the anchored vessels is managed. Leaving of a vessel, needing to deviate from the anchorage, from the group is controlled. If a vessel recognized as a vessel identical to one that left the group requests anchoring after a predetermined period of time has elapsed, the anchoring-requesting vessel is controlled.

Abstract: The present invention relates to: a catalyst activation method for Fischer-Tropsch synthesis; a catalyst regeneration method for Fischer-Tropsch synthesis; and a method for producing a liquid or solid hydrocarbon by using the Fischer-Tropsch synthesis reaction. The temperatures required for a metal carbide producing and activating reaction is markedly lower than existing catalyst activation temperatures, and the catalyst can be activated under conditions that are the same as Fischer-Tropsch synthesis reaction conditions, and thus there is no need for separate reduction equipment in the reactor, and a Fischer-Tropsch synthesis catalyst which has been used for a long time can be regenerated within the reactor without the catalyst being isolated or extracted from the reactor.

Abstract: Disclosed are PEG-modified Exendin-4 analogs and uses thereof. In particular, disclosed are PEG-modified Exendin-4 analogs as shown in formula (I), i.e., PEG-M-X-(Ex-4), or pharmaceutically acceptable salts thereof, as well as Exendin-4 analogs as shown in formula (II), i.e., [Aap]Exendin-4, wherein the symbols are as defined in the specification. Further disclosed are methods for preparing PEG-modified Exendin-4 analogs, uses of PEG-modified Exendin-4 analogs, compositions comprising the same, as well as use of the Exendin-4 analogs in the preparation of the PEG-modified Exendin-4 analogs. In the PEG-modified Exendin-4 analogs, modification by polyethylene glycol occurs in a site-directed manner in the peptide chains of the Exendin-4 analogs. The PEG-modified Exendin-4 analogs can be used to prevent and/or treat diseases and/or symptoms related to decreased activity of GLP-1 receptors, such as type II diabetes.

Abstract: The application of flagellin derivative CZLC31 from Salmonella in preparation of medicines for preventing and treating inflammatory bowel disease (IBD) is introduced in this invention. The CZLC331 protein has a good preventive and therapeutic effect for IBD, such as ulcerative colitis (UC) and Crohn's disease (CD) in this invention. Therefore, this protein can be prepared into the drug for prevention and treatment of IBD. It has been found that the bad efficacy, slow onset, long course of treatment, side effects can be significantly avoided for existing clinical IBD drugs, it can reduce the patient's pain during the treatment in this invention. The rehabilitation and quality of life of the patients have been largely improved. The drug will play an important role in the prevention and treatment of IBD in this invention, and has broad application prospects.

Abstract: An impedance analysis device adapted to an object under test (OUT) includes a signal generator, a signal analysis unit and a processing unit. The signal generator outputs a pulse signal to the OUT. The signal analysis unit acquires a response signal which the OUT responds to the pulse signal, and analyzes the response signal to obtain an analysis parameter. The processing unit coupled to the signal analysis unit receives the analysis parameter, so as to obtain an impedance variation characteristic of the OUT.

Abstract: A method of providing a realistic broadcasting image including an ultra high definition (UHD) image, the method including generating a first encoding stream from a high definition (HD) image, generating a second encoding stream from at least one of a UHD image and an image restored from the first encoding stream, generating a third encoding stream from at least one of the UHD image and an image restored from the second encoding stream, generating a first transmission stream by applying at least one of packetization, synchronization, and multiplying to the first encoding stream and the second encoding stream, generating a second transmission stream by applying at least one of packetization and synchronization to the third encoding stream, transmitting the first transmission stream via a first transmission channel, and transmitting the second transmission stream via a second transmission channel having a lower transmission capacity than the first transmission channel.

Abstract: Disclosed are an apparatus and a method for extracting a highlight section of music. The apparatus for extracting a highlight section of music in accordance with the embodiment of the present invention includes a frame divider that divides an audio file into a plurality of frames having a predetermined sample length; an average energy signal calculator that calculates a signal representing the average magnitude of audio energy for a plurality of samples belonging to each frame for each frame of the plurality of frames; and a highlight section selector that extracts a low frequency signal from the signal representing the average audio energy magnitude for each frame and determines the highlight section from frame sections including maximum points of the low frequency signal.

Abstract: Disclosed is a liver tumor-targeting ultrasound contrast agent. The ultrasound contrast agent includes a gas-generating core and a hyaluronic acid shell. The ultrasound contrast agent can be specifically delivered to liver cells. This specific delivery enables easy differentiation between normal liver cells and liver tumor cells by ultrasound imaging. In addition, the ultrasound contrast agent is highly stable in aqueous condition and causes no cytotoxicity. Also disclosed is a method for preparing the ultrasound contrast agent.

Abstract: The present disclosure relates to a catalyst having metal catalyst nanoparticles supported on natural cellulose fibers and a method of preparing the same, whereby natural cellulose fibers are subjected to specific pretreatment to increase a surface area and form defects on the surface thereof and metal catalyst nanoparticles are then supported on the cellulose catalyst support in a highly dispersed state, thereby providing improved catalysis while allowing production of the catalyst at low cost. The catalyst may be utilized for various catalytic reactions.