Patents Assigned to INSTITUTE
  • LIQUID INTRODUCING PLASMA SYSTEM
    Publication number: 20140271373
    Abstract: A liquid introducing plasma system including a plasma chamber in which a plasma is produced, a plasma generator device which creates the plasma in the chamber, and a spouting device for linearly ejecting a liquid in a linear jet to thereby introduce the liquid into the plasma chamber is disclosed. The plasma system is capable of supplying an ultra-small volume of sample liquid to the plasma while reducing consumption of electrical power required for generation of the plasma.
    Type: Application
    Filed: May 12, 2014
    Publication date: September 18, 2014
    Applicant: NATIONAL UNIV. CORP. TOKYO INSTITUTE OF TECHNOLOGY
    Inventors: Akitoshi OKINO, Hidekazu MIYAHARA, Goro OHBA
  • NUCLEOTIDE-SPECIFIC RECOGNITION SEQUENCES FOR DESIGNER TAL EFFECTORS
    Publication number: 20140271602
    Abstract: The invention relates to methods of altering expression of a genomic locus of interest or specifically targeting a genomic locus of interest in an animal cell, which may involve contacting the genomic locus with a non-naturally occurring or engineered composition that includes a deoxyribonucleic acid (DNA) binding polypeptide having a N-terminal capping region, a DNA binding domain comprising at least five or more Transcription activator-like effector (TALE) monomers and at least one or more half-monomers specifically ordered to target the genomic locus of interest, and a C-terminal capping region, wherein the polypeptide includes at least one or more effector domains, and wherein the polypeptide is encoded by and translated from a codon optimized nucleic acid molecule so that the polypeptide preferentially binds to the DNA of the genomic locus.
    Type: Application
    Filed: May 30, 2014
    Publication date: September 18, 2014
    Applicants: THE BROAD INSTITUTE INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Feng Zhang, Le Cong, Sam Locascio
  • MULTI-USER MULTIPLE-INPUT AND MULTIPLE-OUTPUT (MU-MIMO) TRANSMISSION METHOD AND SYSTEM IN WIRELESS LOCAL AREA NETWORK (WLAN)
    Publication number: 20140269656
    Abstract: Provided is a data transmission method and system in a wireless local area network (WLAN) supporting a multi-user multiple-input and multiple-output (MU-MIMO), the method including determining a type of a first frame to be transmitted to at least one reception terminal, setting, based on a result of the determining, user identification (ID) information indicating an order of the at least one reception terminal, transmitting the first frame to the at least one reception terminal corresponding to the user ID information, receiving, from the at least one reception terminal, a second frame corresponding to the first frame, extracting, based on the received second frame, a beamforming parameter of the at least one reception terminal, and transmitting, to a physical (PHY) layer, the user ID information and the beamforming parameter corresponding to the at least one reception terminal.
    Type: Application
    Filed: February 6, 2014
    Publication date: September 18, 2014
    Applicant: Electronics and Telecommunications Research Institute
    Inventors: Jee Yon CHOI, Jae Woo PARK, Sok Kyu LEE
  • ARTIFICIAL IMMUNE SYSTEM: METHODS OF USE
    Publication number: 20140273209
    Abstract: The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interaction with the immune system.
    Type: Application
    Filed: March 20, 2014
    Publication date: September 18, 2014
    Applicants: SANOFI PASTEUR VAXDESIGN CORPORATION, THE SCRIPPS RESEARCH INSTITUTE, MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY, THE WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH, MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: William L WARREN, Heather FAHLENKAMP, Russell HIGBEE, Anatoly KACHURIN, Conan LI, Mike NGUYEN, Robert PARKHILL, Guzman SANCHEZ-SCHMITZ, Darrell J. IRVINE, Gwendalyn J. RANDOLPH, Nir HACOHEN, Bruce TORBETT
  • METHODS AND COMPOSITIONS FOR SCREENING MODULATORS OF ONCOGENE-INDUCED SENESCENCE
    Publication number: 20140272947
    Abstract: A high-throughput method for identifying a compound or biomolecule that modulates cell senescence involves simultaneously measuring in a cell population exposed to the test compound or biomolecule, the expression of a senescence marker and cell number, wherein each well contains a single test compound; and determining from said simultaneous measurements whether the test compound increases or decreases cell senescence. In various embodiments, the method is useful is identifying compounds that delay the aging process of normal healthy cells, or identifying a compound useful as a tumor suppressor or identifying a compound useful in the treatment of cancer.
    Type: Application
    Filed: March 10, 2014
    Publication date: September 18, 2014
    Applicants: Fox Chase Cancer Center, The Wistar Institute of Anatomy and Biology
    Inventors: Rugang Zhang, Benjamin Guy Bitler, Jeffrey Peterson
  • TECHNIQUES FOR DATA RETRIEVAL IN A DISTRIBUTED COMPUTING ENVIRONMENT
    Publication number: 20140280247
    Abstract: Enhanced techniques for data retrieval in a distributed computing environment are described. A computing node of a distributed computing environment may receive a data request. The computing node may include one or more subsets of data. The computing node may be configured to search among the one or more subset of data for a beginning of a data range that is responsive to the data request. The computing node may be further configured to forward a data range responsive to the search to another computing node of the distributed computing system to be merged with one or more additional data ranges. Other embodiments are described and claimed.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Applicant: SAS INSTITUTE INC.
    Inventors: Joseph Albert F.S. Pingenot, Christopher Daniel Bailey
  • ADVANCED SEMICONDUCTOR-CONDUCTOR COMPOSITE PARTICLE STRUCTURES FOR SOLAR ENERGY CONVERSION
    Publication number: 20140261646
    Abstract: An electrode for solar conversion including a porous structure configured to contain therein at least one of a catalyst, a chromophore, and a redox couple. The porous structure has a set of electrically conductive nanoparticles adjoining each other. The set of electrically conductive nanoparticles forms a meandering electrical path connecting the nanoparticles together. The porous structure has an atomic layer by layer deposited semiconductive coating disposed conformally on the electrically conductive nanoparticles to form an exterior surface for reception of charge carriers.
    Type: Application
    Filed: March 18, 2014
    Publication date: September 18, 2014
    Applicants: RESEARCH TRIANGLE INSTITUTE, DUKE UNIVERSITY, NORTH CAROLINA STATE UNIVERSITY, UNIVERSITY OF NORTH CAROLINA CHAPEL HILL
    Inventors: Paul G. HOERTZ, Qing PENG, Berc KALANYAN, Do Han KIM, Leila ALIBABAEI, Jie LlU, Thomas J. MEYER, Gregory N. PARSON, Jeffrey T. GLASS, Mark LOSEGO
  • PLATFORMS, SYSTEMS, SOFTWARE, AND METHODS FOR ONLINE CPR TRAINING AND CERTIFICATION
    Publication number: 20140272869
    Abstract: Disclosed are web-based CPR training and certification platforms comprising: 1) a controller device comprising: a first mode for collecting student compression data; a second mode for collecting student breath data; and a software module for transmitting the data to a server application; and 2) a server processor configured to provide an application comprising: a training mode, a practice mode, and a certification mode; a software module for providing a student interface; and a software module for providing an instructor interface. Optionally, feedback on student CPR psychomotor skills is provided in the form of a single-player or multi-player game played by performing the skills.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Health & Safety Institute
    Inventors: John William HAMBELTON, William ROWE, Ralph M. SHENEFELT, William H. CLENDENEN, Adam KEISLING, Frank POWERS, JR.
  • MAGNESIUM MOTHER ALLOY AND METAL ALLOY
    Publication number: 20140271333
    Abstract: Disclosed are a magnesium mother alloy, a manufacturing method thereof, a metal alloy using the same, and a method of manufacturing the metal alloy. In particular, there are provided a magnesium mother alloy with improved oxidation and ignition properties, and a manufacturing method thereof, and also provided a metal alloy with low cost that is suitable for design purposes using the magnesium mother alloy, and a method of manufacturing the metal alloy. The magnesium mother alloy includes a plurality of magnesium grains, and scandium dissolved in the magnesium grains, or a scandium compound crystallized at grain boundaries which are not inside but outside the magnesium grains. Also, the metal alloy suitable for design purposes is manufactured at low cost by adding the magnesium mother alloy containing scandium into a magnesium alloy or an aluminum alloy.
    Type: Application
    Filed: May 27, 2014
    Publication date: September 18, 2014
    Applicant: Korea Institute of Industrial Technology
    Inventors: Shea Kwang Kim, Jung Ho Seo, In Kyum Kim
  • Complex Disease Resistant Monocot Having Optimized Agronomic Characteristics
    Publication number: 20140283209
    Abstract: The present inventors isolated many promoters having various expression characteristics from monocots, connected the OsWRKY45 gene downstream of these promoters, and then re-introduced them into a monocot (rice plant), and thereby strived to produce a rice line having both complex disease resistance and excellent agronomic traits. As a result, the present inventors succeeded in producing transgenic plants having both disease resistance and good agronomic traits by expressing OsWRKY45 using upstream sequences of the EF1? or OsUbi7 gene as promoters.
    Type: Application
    Filed: March 1, 2012
    Publication date: September 18, 2014
    Applicant: NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES
    Inventors: Hiroshi Takatsuji, Shingo Goto
  • USE OF ANTAGONISTS OF GROWTH HORMONE OR GROWTH HORMONE RECEPTOR TO PREVENT OR TREAT STRESS-SENSITIVE PSYCHIATRIC ILLNESS
    Publication number: 20140274900
    Abstract: The invention relates to methods for treating stress sensitive condition. For instance a subject having or at risk of having a stress-sensitive condition may be treated with a growth hormone (GH) antagonist in an effective amount to treat the stress sensitive condition. The GH antagonist may be, for instance, a growth hormone receptor (GHR) antagonist.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Massachusetts Institute of Technology
    Inventor: Ki Ann Goosens
  • Portable Blood Count Monitor
    Publication number: 20140273064
    Abstract: This disclosure describes the development of a sample preparation, measurement, and analysis method that permits accurate characterization of red blood cells, platelets, and white blood cells, including a 3-part differential of the white blood cells count, to be performed on small volumes of a biological sample. This method is compatible with compact and portable instrumentation that permits the sample collection to be performed in a subject's home and analysis to be performed elsewhere by transmission of the data to a laboratory or doctor's office.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicants: The Regents of The University of California, Tahoe Institute for Rural Health Research, LLC
    Inventors: Zachary Smith, Tingjuan Gao, Stephen Lane, Sebastian Wachmann-Hogiu, Denis Dwyre, Laurence Heifetz, James Hood, Dennis Matthews, Keith Tatsukawa
  • ENGINEERING AND OPTIMIZATION OF IMPROVED SYSTEMS, METHODS AND ENZYME COMPOSITIONS FOR SEQUENCE MANIPULATION
    Publication number: 20140273234
    Abstract: The invention provides for engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are compositions and methods related to components of a CRISPR complex particularly comprising a Cas ortholog enzyme.
    Type: Application
    Filed: June 2, 2014
    Publication date: September 18, 2014
    Applicants: The Board Institute, Inc., Massachusetts Institute of Technology
    Inventors: Feng ZHANG, Fei RAN
  • Polymer-doped vertically-aligned nematic liquid crystals
    Patent number: 8834742
    Abstract: A system having a vertically-aligned negative delta E nematic liquid crystal host material and a small amount of liquid crystal polymer is provided. The liquid crystal polymer improves the switching speed of a vertically aligned nematic system without sacrificing contrast or viewing angle.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: September 16, 2014
    Assignees: California Institute of Technology, LC Vision, LLC
    Inventors: Julia A. Kornfield, Michael Wand, Zuleikha Kurji
  • Method and apparatus for transmitting and receiving UHD broadcasting service in digital broadcasting system
    Patent number: 8839333
    Abstract: A method and apparatus for transmitting and receiving Ultra High Definition (UHD) broadcasting service in a digital broadcasting system are provided. The method includes receiving a TS through a transport channel, determining whether or not the TS includes information about an association relation with other TSs, analyzing the information about the association relation from the TS, determining whether or not the TS includes information about a program provided in association with the other TSs based on the information about the association relation, extracting the information about the program from the TS, and obtaining the program based on the information about the program. In accordance with the present invention, high definition broadcasting service can be provided because a broadcasting program having a great transmission bandwidth can be transmitted and received in a digital broadcasting system.
    Type: Grant
    Filed: July 31, 2012
    Date of Patent: September 16, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Joon Young Jung, Dong Joon Choi, Nam Ho Hur
  • Treatment of friedreich's ataxia using histone deacetylase inhibitors
    Patent number: 8835502
    Abstract: The invention provides methods of treating Friedreich's ataxia using histone deacetylase inhibitors.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: September 16, 2014
    Assignee: The Scripps Research Institute
    Inventors: Joel M. Gottesfeld, Kai Jenssen, David M. Herman, Ryan Burnett, C. James Chou
  • Anode substrate
    Patent number: 8835050
    Abstract: An anode substrate which enables achievement of a battery having a high output voltage and a high energy density, and being superior in charge and discharge cycle characteristics; a secondary cell in which the anode substrate is used; a resin composition for use in forming the anode substrate; and a method for producing the anode substrate are provided. According to anode substrate 10 including metal film 13 formed on support 11 provided with patterned organic film 12 molded by a thermal imprint process or a photoimprint process, a battery having a high output voltage and a high energy density, and being superior in charge and discharge cycle characteristics can be provided.
    Type: Grant
    Filed: November 10, 2008
    Date of Patent: September 16, 2014
    Assignees: Tokyo Ohka Kogyo Co., Ltd, Kanto Gakuin University Surface Engineering Research Institute
    Inventors: Koichi Misumi, Mitsuhiro Watanabe, Hideo Honma
  • Amplified electrokinetic fluid pumping switching and desalting
    Patent number: 8834696
    Abstract: The present invention provides a device and methods of use thereof for desalting a solution. The methods, inter-alia, make use of a device comprising microchannels, which are linked to conduits, whereby induction of an electric field in the conduit results in the formation of a space charge layer within the microchannel. The space charge layer provides an energy barrier for salt ions and generates an ion depletion zone proximal to the linkage region between the microchannel and the conduit. The method thus enables the removal of salt ions from the region proximal to the conduit and their accumulation in a region distant from the conduit, within the microchannel.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: September 16, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Sung Jae Kim, Jongyoon Han
  • Copolymer and method for manufacturing the same
    Patent number: 8835584
    Abstract: In one embodiment of the disclosure, a copolymer and method for manufacturing the same are provided. The copolymer is copolymerized from a composition including: (a) a first hydrophilic monomer, including itaconamic acid, itaconamic salt, or combinations thereof; and (b) a second hydrophilic monomer, including acrylic acid, acrylic salt, acrylamide, or combinations thereof.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: September 16, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Tun-Fun Way, Yu-Ting Chen, Jiun-Jy Chen, Kelly Teng
  • Tactile display and CAD system
    Patent number: 8836660
    Abstract: Provided is a technique capable of allowing a person to perceive a fine relief on an object surface clearly. A tactile device of a tactile display slides above an object. The tactile device comprises three rods which are free to move up and down. Lower ends of the rods are in contact with a surface of the object. Upper ends of respective rods touch a palmar-side skin equivalent to positions of three joints of a first finger or a second finger. When the tactile device is slid, upper ends of respective rods move up and down in accordance with a surface relief of the object. In response to the movement of the tactile device, the three rods push three finger joint positions of the palmar-side skin with a stroke equal to a height of the relief.
    Type: Grant
    Filed: September 28, 2009
    Date of Patent: September 16, 2014
    Assignees: Toyota Jidosha Kabushiki Kaisha, National University Corporation Nagoya Institute of Technology
    Inventors: Akihito Sano, Yoshihiro Tanaka, Hideo Fujimoto, Eisuke Kajisa, Kenji Wada