Abstract: The invention provides for systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells and methods for selecting specific cells by introducing precise mutations utilizing the CRISPR-Cas system.

Abstract: Modular laboratory workbenches and work surface accessories are provided. Modular laboratory workbenches may include a spine structure including multiple modules with core passageways for routing utilities. At least one spine structure module may include circuit breakers behind a panel for local electrical power control. The spine structure may include a top with angled faces that provide power outlets, gas terminals, and other utilities. Between angled faces, an accessory support structure may be provided that supports a backsplash in a center channel and provides accessory slots on both sides of the center channel to receive and support interchangeable accessories including monitor arms, tablet arms, gas turrets, supplemental lights, etc. Cantilever brackets of various heights may attach to the spine structure and support work surfaces that are translatable to provide access to the utilities provided on the angled faces of the spine structure.

Abstract: Provided is an electrolyte solution for a magnesium battery, containing a mesoionic compound represented by the following general formula (1): (in general formula (1), R1 and R2 are each independently a C1-7 hydrocarbyl group or oxygen-containing hydrocarbyl group and X is O or S).

Abstract: The present invention relates to an apparatus and method for performing cooperative autonomous driving between a vehicle and a driver. For this, a cooperative autonomous driving apparatus according to the present invention includes a driver state determination unit for determining a state of a driver and calculating the state of the driver as a risk index. An autonomous driving control unit classifies section characteristics of respective sections included in a path to a destination corresponding to the driver based on section data stored in a database (DB), and controls autonomous driving of a vehicle in which the driver is riding, based on a driving environment recognized for the path to the destination corresponding to the driver. A driving control determination unit determines driving modes of the respective sections included in the path based on the state of the driver and the section characteristics.

Abstract: Disclosed herein is an apparatus for analyzing the vulnerability of a wireless local area network (LAN). The apparatus includes a collection unit, an analysis unit, and an attack unit. The collection unit collects packets transmitted and received in a wireless LAN service. The analysis unit analyzes the state of a network using the collected packets. The attack unit makes a wireless attack against an attack target using the state of the network, and controls the mode switching of a device driver based on an operating mode.

Abstract: In the present invention, a control section of a CRM server performs editing processing for TPO (the time, the place, and the occasion) requirements. Next, a control section of a TPO server registers the TPO requirements in order to convert the same to TPO definitions. Then, the control section performs setting processing for the TPO definitions. A portable terminal identifies the current location and the current time. Then, a control section verifies TPO definition state transitioning. If transitioning of the TPO definition state is detected, the control section performs TPO definition state transition notification processing. The control section of the portable terminal performs individual control processing on the basis of the TPO definitions.

Abstract: The present invention provides a method of diagnosing a cyathostomin infection, said method comprising the step of identifying a level of anti-cyathostomin larval antigen antibodies in a sample, wherein a level of anti-cyathostomin larval antigen antibodies is indicative of a cyathostomin infection.

Abstract: A multiple viewpoint rendering method for a multiplayer online game and a multiple viewpoint rendering server using the same, the multiple viewpoint rendering server including a game progress information receiving unit configured to receive game progress information from an online game server, a viewpoint setting unit configured to obtain viewpoint information corresponding to each of the multiple terminals, a game image rendering unit configured to render game images corresponding to the multiple terminals, respectively, based on the game progress information and the viewpoint information, and a rendered image providing unit configured to provide the multiple terminals with the rendered game images corresponding to the multiple terminals, respectively.

Abstract: A Field Effect Transistor (FET) and a method of manufacturing the same are provided. The FET may include a substrate; a source and a drain, one of which is formed on a bulge formed on a top surface of the substrate, and the other of which is formed in the substrate below but laterally offset from the bulge; a gate formed at a position where the bulge and the top surface of the substrate join each other; and a gate dielectric layer formed between the gate and the bulge and also between the gate and the top surface of the substrate. The FET has a vertical configuration, where the source is disposed on top of the bulge while the drain is disposed in the substrate, that is, the source and the drain are not in one same plane. As a result, the FET may have its area significantly reduced. Therefore, it is possible to improve an integration density of an IC and thus reduce cost.

Abstract: Provided is an apparatus for allocating a sequence to a synchronization channel for a node identification (ID), the apparatus including: a base node sequence generator to generate a base sequence that is a sequence for a node ID of a base node; a relay node sequence generator to generate a relay sequence that is a sequence for a node ID of a relay node by transforming the base sequence; a baseband signal generator to generate a baseband signal by mapping the base sequence or the relay sequence to a frequency domain and a time domain; and a transmitter to transmit the baseband signal.

Abstract: Compositions that inhibit or block the interaction between Erbin and ErbB2 and methods of their use are provided. Preferred compositions include peptides that inhibit or block Erbin and ErbB2 interaction under physiologic conditions in a subject. One embodiment provides an isolated peptide fragment of ErbB2 including the C-terminal 15 amino acids of ErbB2. The peptide fragment can be about 15 to 27 amino acids in length.

Abstract: Disclosed herein are an apparatus for generating the privacy-protecting document authentication information and a method of performing privacy-protecting document authentication. The apparatus for generating the privacy-protecting document authentication information includes an electronic signature information generation unit, a multi-dimensional code generation unit, and a multi-dimensional code output unit. The electronic signature information generation unit generates electronic signature information for the content of an input document. The multi-dimensional code generation unit generates a multi-dimensional code corresponding to the generated electronic signature information. The multi-dimensional code output unit outputs the generated multi-dimensional code onto the document.

Abstract: An apparatus for analyzing a permission of an application for a mobile device, the apparatus comprising: an executable file acquisition unit; a file extraction module; and an execution permission analyzing module configured to detect a security risk which can be caused by the permission on the basis of the permission described in the extracted file, wherein the information related to the permission of the application comprises: information on permission that is declared in the application, permission that the application uses and a function that uses the permission of the application.

Abstract: The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.

Abstract: A transmit node receives a transformed correlation matrix or a correlation matrix of a channel coefficient matrix, or a correlation matrix of an interference channel coefficient matrix from each of receive nodes sharing a radio resource. The transmit node determines a precoder based on a value maximizing values determined by the transformed correlation matrix or the correlation matrix of the channel coefficient matrix, or a value minimizing values determined by the correlation matrix of the interference channel coefficient matrix, and precodes a transmit signal by using the determined precoder.

Abstract: Described herein are catalysts for activation of an R—H bond in a R—H substrate and related catalytic matrices, compositions, methods and systems.

Abstract: The present invention relates to regulation of cardiac contractile function. The present invention is based on the discovery that microRNAs contribute to the loss of cardiac contractility. Specifically, miR-25 binds to SERCA2a which results in a loss of function and interferes with Ca2+ handling. Accordingly, the present invention relates to methods of increasing cardiac contractile function by inhibiting miR-25. The invention further provides methods to identify agents that can modulate miR-25 activity, including high throughput screening methods, and provides a means to identify agents that are useful for treating patients having cardiac contractile function associated disorders.

Abstract: Bipolar wave current, is used to electrodeposit a nanocrystalline grain size. Polarity Ratio is the ratio of absolute value of time integrated amplitude of negative and positive polarity current. Grain size can be controlled in alloys of two or more components, at least one of which is a metal, and at least one of which is most electro-active, such as nickel and tungsten and molybdenum. Typically, the more electro-active material is preferentially lessened during negative current. Coatings can be layered, each having an average grain size, which can vary layer to layer and also graded through a region. Deposits can be substantially free of either cracks or voids.

Abstract: Disclosed herein is a fiber-reinforced ceramic composite material honeycomb, including: a plurality of inner tubes, each of which is made of a fiber-reinforced ceramic composite material; and an outer shell which is made of a fiber-reinforced ceramic composite material and which surrounds the plurality of inner tubes.

Abstract: According to example embodiments a TFT includes: a substrate; a gate electrode on the substrate; a gate insulating layer on the gate electrode; a channel layer on the gate insulating layer, the channel layer including an indium-rich metal-oxide layer; a first electrode on one end of the channel layer; a second electrode on the other end of the channel layer; and a passivation layer on the channel layer between the first and second electrodes.