Patents Assigned to INSTITUTE
  • Patent number: 8748101
    Abstract: Methods, compositions, and devices are disclosed which use microRNA to detect, predict, treat, and monitor physiological conditions such as disease or injury. microRNA are isolated and their differential expression is measured to provide diagnostic information. This information may then be utilized for evaluation and/or treatment purposes.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: June 10, 2014
    Assignees: Battelle Memorial Institute, Institute for Systems Biology, The Ohio State University Research Foundation
    Inventors: David Galas, Richard Evan Gelinas, Clay Braden Marsh, Melissa Garnet Piper, Kai Wang, Shile Zhang
  • Patent number: 8748132
    Abstract: A process for preparing an inclusion body-forming protein is provided. A nucleic acid fragment having a nucleotide sequence coding for a modified alkaline phosphatase signal peptide (modified APSP) where leucine at the 13th position in the amino acid sequence shown in SEQ ID NO: 1 is substituted with proline and/or alanine at the 21st position is substituted with the other amino acid, downstream of which nucleotide sequence is bound a nucleotide sequence of a gene of a protein of interest is also provided.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: June 10, 2014
    Assignees: The Chemo-Sero-Therapeutic Research Institute, Teijin Pharma Limited
    Inventors: Hiroshi Nakatake, Akihiro Meta, Kiyotaka Suenaga, Masaki Hirashima, Hiroaki Maeda
  • Patent number: 8748933
    Abstract: Semiconductor nanocrystals including III-V semiconductors can include a core including III-V alloy. The nanocrystal can include an overcoating including a II-VI semiconductor.
    Type: Grant
    Filed: March 12, 2012
    Date of Patent: June 10, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Moungi G. Bawendi, Sang-wook Kim, John P. Zimmer
  • Patent number: 8751172
    Abstract: A viscosity measurement device includes a flexible membrane, an actuation heating element, and a displacement sensor apparatus. The actuation heating element is on and spaced in from an outer periphery of the flexible membrane. The displacement sensor apparatus is coupled to the flexible membrane and measures and outputs a displacement signal representative of a viscosity of a fluid in contact with the flexible membrane.
    Type: Grant
    Filed: June 29, 2010
    Date of Patent: June 10, 2014
    Assignee: Rochester Institute of Technology
    Inventors: Ivan Puchades, Lynn Fuller
  • Patent number: 8749546
    Abstract: A digital 3D object processing apparatus is provided, for processing a digital 3D object comprising a plurality of sub-objects belonging to one of a plurality of digital 3D object formats, comprising: a communication unit coupled to a first outer computer through a network; an interface unit coupled to the communication unit, receiving an instruction from the first outer computer; and a control command unit coupled to the communication unit, transmitting a control command to the first outer computer, wherein the first outer computer establishes a relative position of the plurality of sub-objects according to the control command, and transmits the relative position and the plurality of sub-objects to the communication unit.
    Type: Grant
    Filed: December 13, 2010
    Date of Patent: June 10, 2014
    Assignee: Institute for Information Industry
    Inventors: Susan Dong, Ren-Dar Yang, Tzu-Chieh Tien, Te-Lu Tsai, Yu-Shiang Hung
  • Patent number: 8748469
    Abstract: Presently provided are compounds according to the formula (I) or (II), and pharmaceutical compositions comprising the compounds, wherein R1, R4, and R5 are defined herein. Such compounds and compositions are useful for modulating an activity of indoleamine 2,3-dioxygenase; treating indoleamine 2,3-dioxygenase (IDO) mediated immunosuppression; treating a medical conditions that benefit from the inhibition of enzymatic activity of indoleamine -2,3-dioxygenase; enhancing the effectiveness of an anti-cancer treatment comprising administering an anti-cancer agent; treating tumor-specific immunosuppression associated with cancer; and treating immunosupression associated with an infectious disease.
    Type: Grant
    Filed: April 24, 2009
    Date of Patent: June 10, 2014
    Assignees: NewLink Genetics Corporation, Lankeanau Institute for Medical Research
    Inventors: Mario R. Mautino, Sanjeev Kumar, Firoz Jaipuri, Jesse Waldo, Tanay Kesharwani, Nicholas N. Vahanian, Charles J. Link
  • Patent number: 8749619
    Abstract: In illustrative implementations of this invention, multi-path analysis of transient illumination is used to reconstruct scene geometry, even of objects that are occluded from the camera. An ultrafast camera system is used. It comprises a photo-sensor (e.g., accurate in the picosecond range), a pulsed illumination source (e.g. a femtosecond laser) and a processor. The camera emits a very brief light pulse that strikes a surface and bounces. Depending on the path taken, part of the light may return to the camera after one, two, three or more bounces. The photo-sensor captures the returning light bounces in a three-dimensional time image I(x,y,t) for each pixel. The camera takes different angular samples from the same viewpoint, recording a five-dimensional STIR (Space Time Impulse Response). A processor analyzes onset information in the STIR to estimate pairwise distances between patches in the scene, and then employs isometric embedding to estimate patch coordinates.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: June 10, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Ahmed Kirmani, Ramesh Raskar, James Davis
  • Patent number: 8750065
    Abstract: An apparatus includes one or more temperature sensing and memory devices each having one or more memristors. A controller device is coupled to the temperature sensing and memory devices A processing device is coupled to the controller device and includes at least one of hardware logic configured to be capable of implementing or a processor coupled to a memory and configured to execute programmed instructions stored in the memory comprising: issuing a record instruction and a write instruction with a write address to the controller device to record the write time for the memristor at the write address to transition from one of the first and second states to the other states; receiving from the controller device the recorded time; determining and providing a temperature of the memristor at the write address based on the received write time.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: June 10, 2014
    Assignee: Rochester Institute of Technology
    Inventors: Cory Merkel, Dhireesha Kudithipudi
  • Patent number: 8748983
    Abstract: An embedded source/drain MOS transistor and a formation method thereof are provided. The embedded source/drain MOS transistor comprises: a semiconductor substrate; a gate structure on the semiconductor substrate; and a source/drain stack embedded in the semiconductor substrate at both sides of the gate structure with an upper surface of the source/drain stack being exposed, wherein the source/drain stack comprises a dielectric layer and a semiconductor layer above the dielectric layer. The present invention can cut off the path for the leakage current from the source region and the drain region to the semiconductor substrate, thereby reducing the leakage current from the source region and the drain region to the semiconductor substrate.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: June 10, 2014
    Assignee: Institute of Microelectronics, Chinese Academy of Sciences
    Inventors: Huicai Zhong, Chao Zhao, Qingqing Liang
  • Patent number: 8750957
    Abstract: An embodiment of the invention provides a neural probe containing a plurality of nanoscale recording electrodes. The recording electrodes have a width of 1 micron or less and a distance between adjacent recording electrodes is 10 microns or less. Another embodiment of the invention provides a neural probe comprising a plurality of microfabricated recording electrodes located on a polymer base material, such as a flexible polymer cantilever.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: June 10, 2014
    Assignee: California Institute of Technology
    Inventors: Hongxing Tang, Michael L. Roukes, Richard Renaud
  • Patent number: 8747631
    Abstract: The present disclosure relates to an apparatus and method utilizing double glow discharge for sputter cleaning of a selected surface. The surface may include the inner surface of a hollow substrate such as a tube which inner surface may then be coated via magnetron sputter deposition.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: June 10, 2014
    Assignee: Southwest Research Institute
    Inventors: Ronghua Wei, Edward Langa, Sabrina L. Lee
  • Patent number: 8750269
    Abstract: A transmit power control method of a first station in a wireless LAN (WLAN) system includes: receiving path loss information from an (access point) AP, the path loss information containing a maximum value among path losses between the AP and at least one or more stations included in the WLAN system; controlling a transmit power by using the path loss information; and transmitting a frame according to the controlled transmit power. In said controlling the transmit power by using the path loss information, the transmit power is controlled by using a path loss obtained by adding the maximum value and a path loss between the first station and the AP or by using the path loss between the first station and the AP.
    Type: Grant
    Filed: October 22, 2010
    Date of Patent: June 10, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Il-Gu Lee, Jeeyon Choi, Sok-Kyu Lee
  • Patent number: 8751024
    Abstract: Disclosed are an apparatus and a method of providing contents. The apparatus of providing the contents may include a receiving unit to receive, from a contents provider, contents and information about a contents providing location, a local group setting unit to search for at least one cell based on the information about the contents providing location and to set the retrieved cell as a content providing location group of the contents, and a transmitting unit to transmit the contents to the set content providing location group. The object based audio contents may be consecutively replayed based on an identical audio preset.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: June 10, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Yong Ju Lee, Tae Jin Lee, Jeong Il Seo, In Seon Jang, Dae Young Jang, Seung Kwon Beack, Jae Hyoun Yoo, Min Je Kim, Kyeong Ok Kang, Jin Woong Kim, Jin Woo Hong, Seung Chul Ham
  • Patent number: 8747987
    Abstract: A composite panel and its manufacture are described. Ultra-thick bamboo/wood and solid wood composite panels are comprised of core board, surface board and back board. The core board is composed of ultra-thick peeling veneers with thickness of 6 to 12 mm. Both surface board and back board are made of bamboo or wood. The core board comprises several layers of the ultra-thick veneers, and the veneers of contiguous layer are assembled with parallel structure. A glue layer is arranged between contiguous veneers; adhesive in the glue layer is aqueous macromolecule isocyanate adhesive. The ultra-thick veneers of the core layer are the veneers with stress degradation treatment, i.e., punctate or line segment cracks are formed along the grain of the veneer's loose side in each layer.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: June 10, 2014
    Assignee: Research Institute of Wood Industry, Chinese Academy of Forestry
    Inventors: Wenji Yu, Yanglun Yu, Yue Zhou, Rongxian Zhu, Dinghua Ren
  • Patent number: 8750885
    Abstract: An inter-cell interference mitigation method in an orthogonal frequency division multiple access (OFDM)-based cellular system includes: dividing wireless resources into a resource group for fractional frequency reuse and a resource group for removing inter-cell interference; and re-dividing the resource group for fractional frequency reuse into particular resource groups numbering the same as a number of cell types of fractional frequency reuse, and applying a maximum transmission power to a particular resource group according to a cell type for fractional frequency reuse.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: June 10, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventors: Jae Young Ahn, Hyun Kyu Chung
  • Patent number: 8751097
    Abstract: A method and system for using Equivalent Time Sampling to improve the effective sampling rate of sensor data, and using the improved-resolution data for diagnosis and control. Data samples from existing sensors are provided, where the sampling rate of the existing sensors is not sufficient to accurately characterize the parameters being measured. High-resolution data sets are reconstructed using Equivalent Time Sampling. High-resolution input data sets are used in a system model to simulate the performance of the system being measured. Results from the system model, and high-resolution output data sets from Equivalent Time Sampling, are provided to an estimator, which provides accurate estimation of measured quantities and estimation of quantities not measured. Output from the estimator is used for fault diagnosis and control of the system being measured.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: June 10, 2014
    Assignees: GM Global Technology Operations LLC, Indian Institute of Technology Kharagpur
    Inventors: Soumen De, Pattada A. Kallappa, Pulak Bandyopadhyay, Siddhartha Mukhopadhyay, Somnath Sengupta, Alok Kanti Deb
  • Patent number: 8748670
    Abstract: The present invention provides methods comprising reacting a first carboxylic acid or ester with a second carboxylic acid or ester in the presence of a metal oxide comprising Zr, Ce, Mn and O to produce at least one ketone.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: June 10, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Herui Dou, Yuriy Roman-Leshkov
  • Patent number: 8746144
    Abstract: A detonator includes a high voltage switch, an initiator and an initiating pellet. The detonator also includes a low voltage to high voltage firing set coupled to the switch and initiator such that the detonator includes a high voltage power source and initiator in an integrated package. The detonator may also include inductive powering and communications, a microprocessor, tracking and/or locating technologies, such as RFID, GPS, etc., and either a single or combination explosive output pellet. The combination explosive pellet has a first explosive having a first shock energy and a high brisance secondary explosive in the output pellet having a second shock energy greater than the shock energy of the first explosive. Systems are also provided for facilitating fast and easy deployment of one or more detonators in the field.
    Type: Grant
    Filed: May 30, 2013
    Date of Patent: June 10, 2014
    Assignee: Battelle Memorial Institute
    Inventors: Richard W. Givens, Ronald L. Loeser, Roger F. Backhus
  • Patent number: 8751112
    Abstract: A danger sensing apparatus includes a data collecting unit disposed at each of a side rear-view mirror of the vehicle and an inner portion of the vehicle to collect image data of a side region of the vehicle and a situation of a door region of the inner portion of the vehicle as data; a data analyzing unit analyzing the data collected from the data collecting unit to analyze a danger object approaching an outer side of the vehicle and the situation of the door region of the inner portion of the vehicle; and a controlling unit controlling operations of a drive train of the vehicle and the door based on a signal analyzed from the data analyzing unit.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: June 10, 2014
    Assignee: Electronics and Telecommunications Research Institute
    Inventor: Moo Seop Kim
  • Patent number: 8748250
    Abstract: The present invention provides a method for integrating the dual metal gates and the dual gate dielectrics into a CMOS device, comprising: growing an ultra-thin interfacial oxide layer or oxynitride layer by rapid thermal oxidation; forming a high-k gate dielectric layer on the ultra-thin interfacial oxide layer by physical vapor deposition; performing a rapid thermal annealing after the deposition of the high-k; depositing a metal nitride gate by physical vapor deposition; doping the metal nitride gate by ion implantation with P-type dopants for a PMOS device, and with N-type dopants for an NMOS device, with a photoresist layer as a mask; depositing a polysilicon layer and a hard mask by a low pressure CVD process, and then performing photolithography process and etching the hard mask; removing the photoresist, and then etching the polysilicon layer/the metal gate/the high-k dielectric layer sequentially to provide a metal gate stack; forming a first spacer, and performing ion implantation with a low energy
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: June 10, 2014
    Assignee: Institute of Microelectronics, Chinese Academy of Sciences
    Inventors: Qiuxia Xu, Gaobo Xu