Abstract: The object of the present invention is to provide a method for incorporating an arbitrary protein, lipid, carbohydrate, or nucleic acid into an exosome. The object can be solved by a method for preparing an exosome, comprising the steps of: (a) adding a biological toxin having a perforating activity to a medium containing cells and incubating the mixture, (b) adding ATP and incubating the mixture, and (c) adding a medium containing calcium ion and incubating the mixture.

Abstract: Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compounds can be, for example, estrogen receptor beta (ER?) agonists. In some examples, the compounds can be selective ER? agonists. Also provided herein are methods of treating, preventing, or ameliorating cancer in a subject, suppressing tumor growth in a subject, treating an inflammatory disease in a subject, treating a neurodegenerative disease in a subject, treating a psychotropic disorder in a subject, or a combination thereof, by administering to a subject a therapeutically effective amount of one or more of the compounds or compositions described herein, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention provides dihydrooxydiazinone compounds of general formula (I) in which R1, R2, R3, and R4, are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative diseases, as a sole agent or in combination with other active ingredients.

Abstract: The present specification relates to a copolymer including a first unit represented by Chemical Formula 1; and a second unit represented by Chemical Formula 2, and an organic solar cell including the same.

Abstract: Provided is a perovskite film including crystal grains with a crystalline structure of [A][B][X]3.n[C], wherein [A], [B], [X], [C] and n are as defined in the specification. The present disclosure further provides a precursor composition of perovskite film, method for producing of perovskite film, and semiconductor element including such films, as described above. With the optimal lattice arrangement, the perovskite film shows the effects of small surface roughness, and the semiconductor element thereof can thus achieve high efficiency and stability even with large area of film formation, thereby indeed having prospect of the application.

Abstract: In the apparatus for controlling a transmission for lossless packet forwarding, when a failure is detected on one of a plurality of forwarding paths set between a transmitting node and a receiving node, packet transmission of a flow associated with the path in which the failure occurs is stopped, when the path in which the failure occurs is recovered, packet transmission of the flow is resumed, and the receiving node temporarily extends the bandwidth of the flow.

Abstract: A Raman detection system has a Raman spectrometer and a fixing light shielding stand. One end of the fixing light shielding stand is fixedly connected to the Raman spectrometer, and the other end is disposed with an entrance groove for a needle-like SERS probe to enter. A slot for fixing the needle-like SERS probe is formed at an end of the entrance groove, and the slot and the needle-like SERS probe match in shape and size. The Raman detection system has a fixing light shielding device with a dark color groove and a focal length. The groove can be used for limiting the rolling of the curved surface structure of the needle-like SERS probe. A laser can be focused on the curved surface more accurately by adjusting the distance from the instrument detector to the SERS probe.

Abstract: Ferrimagnetic oscillator magnetometers do not use lasers to stimulate fluorescence emission from defect centers in solid-state hosts (e.g., nitrogen vacancies in diamonds). Instead, in a ferrimagnetic oscillator magnetometer, the applied magnetic field shifts the resonance of entangled electronic spins in a ferrimagnetic crystal. These spins are entangled and can have an ensemble resonance linewidth of approximately 370 kHz to 10 MHz. The resonance shift produces microwave sidebands with amplitudes proportional to the magnetic field strength at frequencies proportional to the magnetic field oscillation frequency. These sidebands can be coherently averaged, digitized, and coherently processed, yielding magnetic field measurements with sensitivities possibly approaching the spin projection limit of 1 attotesla/?{square root over (Hz)}. The encoding of magnetic signals in frequency rather than amplitude relaxes or removes otherwise stringent requires on the digitizer.

Abstract: A spherical LED chip, a method for manufacturing the same, and a display panel, and a method for spherical LED chip transfer are provided. The spherical LED chip includes a first electrode, a second electrode surrounding the first electrode and having magnetism, and a first insulating protective layer arranged at the outside of the first electrode. The first insulating protective layer and the second electrode form an LED housing configured to wrap the first electrode and with a spherical outer contour.

Abstract: A user equipment (UE) and a base station (BS) are provided. The UE monitors a plurality of semi-persistent scheduling (SPS) physical downlink shared channel (PDSCH) resources, and determines an SPS Hybrid Automatic Repeat reQuest acknowledge (HARQ-ACK) bit order of a plurality of SPS HARQ-ACK bits, corresponding to the SPS PDSCH resources, in a codebook according to a time-domain position, a component carrier index and a configuration index of each SPS PDSCH resource. Afterwards, the UE generates an HARQ-ACK message including the codebook according to the SPS HARQ-ACK bit order, and transmits the HARQ-ACK message on a physical uplink control channel (PUCCH) resource to the BS.

Abstract: Disclosed herein are compositions and methods for modulating cereblon neosubstrates. A small molecule modulator of Formula (I*), or a pharmaceutically acceptable salt or solvate thereof can be used to modulate cereblon neosubstrates.

Abstract: Disclosed is a method of preparing a cathode active material useful in a sodium ion secondary battery having high reversible capacity and excellent cycle characteristics. The method for preparing a cathode active material composed of Zrw-doped NaxLiyMzOa includes the steps of (A) doping LiyMzOa with Zrw to provide Zrw-doped LiyMzOa; and (B) dissociating Li ion from the Zrw-doped LiyMzOa and inserting Na ion thereto to provide the Zrw-doped NaxLiyMzOa, wherein M is selected from Ti, V, Cr, Mn, Fe, Co, Ni, Mo, Ru, and combinations thereof, and wherein 0.005<w<0.05, 0.8?x?0.85, 0.09?y?0.11, 7?x/y?10, 0.7?z?0.95, and 1.95?a?2.05. When the cathode active material is used for manufacturing a cathode for a sodium ion secondary battery, the battery can substitute for a conventional, expensive lithium ion secondary battery.

Abstract: A balloon type retinal stimulation device includes: a substrate unit having an insertion portion to be inserted into an eyeball; and a stimulation unit provided at one or both of one and the other surfaces of the substrate unit. The insertion portion is expandable and contractible as a fluid is injected into and discharged from an inside of the injection portion. When the insertion portion expands, one surface of the insertion portion matches a shape of the retina such that the stimulation unit is brought into close contact with the retina on which an image is formed, and the other surface of the insertion portion comes into close contact with an inner surface of the eyeball that is not a region of retina on which an image is formed, to support the insertion portion that is in contact with the region of retina on which an image is formed.

Abstract: A computing device selects new test configurations for testing software. Software under test is executed with first test configurations to generate a test result for each test configuration. Each test configuration includes a value for each test parameter where each test parameter is an input to the software under test. A predictive model is trained using each test configuration of the first test configurations in association with the test result generated for each test configuration based on an objective function value. The predictive model is executed with second test configurations to predict the test result for each test configuration of the second test configurations. Test configurations are selected from the second test configurations based on the predicted test results to define third test configurations. The software under test is executed with the defined third test configurations to generate the test result for each test configuration of the third test configurations.

Abstract: Disclosed are a coating for glass molding, a preparation method and application thereof and a mold having the coating. The coating includes a nitride layer and nano precious metal particles which are dispersed in the nitride layer. A surface roughness of the coating is 2-12 nm. The preparation method of the coating includes: cleaning a substrate and targets under an inert gas; and under a mixed atmosphere of nitrogen and the inert gas, depositing, with a high-purity W target, a high-purity Cr target and a precious metal inserted Cr target, a Cr intermediate layer, a nitride layer and nano precious metal particles on a surface of the substrate. The coating has good oxidation resistance and excellent anti-adhesion property. Moreover, the coating effectively inhibits the adhesion between the glass body and the mold.

Abstract: Disclosed herein are a method and apparatus of broadcast gateway signaling for channel bonding. The apparatus for broadcast gateway signaling includes an input formatting unit configured to generate baseband packets corresponding to channel bonding; and a stream partitioner configured to allocate the baseband packets to two or more RF channels of the channel bonding for generating an outer tunnel data stream, the outer tunnel data stream generated in different ways according to a plurality of operation modes for the channel bonding.

Abstract: A polymer binder with high peel strength is used in a secondary lithium battery. The polymer binder is obtained by a ring-opening reaction of polyvinylene carbonate by a nucleophile. The polyvinylene carbonate accounts for 10-90% of the total mass of the polymer binder while the nucleophile accounts for 10-90% of the total mass of the polymer binder. The polymer binder has high peel strength (0.02-0.6 N/mm) and high decomposition voltages (4.5-6.0 V), and can be used as an electrode material binder in a secondary lithium battery.

Abstract: Disclosed herein are a method, apparatus and storage medium for image encoding/decoding using a reference picture. A picture is divided into multiple sub-pictures. The sub-pictures of the picture share a reference picture list. In order to determine sub-pictures that share the reference picture list, specific information is signaled from an encoding apparatus to a decoding apparatus. For each sub-picture that does not share a reference picture list for an additional sub-picture, a reference picture list for the sub-picture is separately configured.

Abstract: Methods are described herein for upgrading ad refining hydrocarbons, and producing at least one petrochemical product, the method including: preparing a reaction mixture by adding at least two of: a quantity of bioethanol, a quantity of hydrocarbon, and a quantity of water to a reactor containment; combining the reaction mixture with a quantity of catalyst in the reactor containment; applying reaction conditions to the reactor containment thereby generating supercritical conditions for the reaction mixture and obtaining a product mixture; and extracting at least one petrochemical product from the product mixture.

Abstract: A method for discovering an unexploded ordnance in a target area includes: acquiring first feedback signals respectively corresponding to detection regions, the first feedback signals being first induced electromotive force signals; judging whether there is any abnormal signal in the first feedback signals, if there is the abnormal signal, determining the detection region corresponding to the abnormal signal is an abnormal region; acquiring second feedback signals respectively corresponding to detection sites in the abnormal region, the second feedback signals being magnetic field gradient signals; acquiring third feedback signals respectively corresponding to the detection sites, the third feedback signals being second induced electromotive force signals; acquiring location information of the detection sites; obtaining a feature spatial distribution map of the abnormal region; and judging whether there is any unexploded ordnance in the abnormal region according to the feature spatial distribution map.