Patents Assigned to INSTITUTE
  • Patent number: 11594655
    Abstract: A method and device for automatic film expansion and a storage medium are provided. The method includes the following. Perform overall stretching on an expanded film. An interval between each two adjacent LED wafers on the expanded film is monitored in real time. When an interval between two adjacent LED wafers on the expanded film is greater than or equal to a preset target interval, stop performing overall stretching, and search the expanded film for a local region where an absolute difference between an interval between two adjacent LED wafers and the preset target interval is greater than a preset error threshold. When the local region exists on the expanded film, perform local stretching on the local region until an absolute difference between an interval between each two adjacent LED wafers in the local region and the preset target interval is less than or equal to the preset error threshold.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: February 28, 2023
    Assignee: CHONGQING KONKA PHOTOELECTRIC TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Renjie Jiang, Guangwei Zhong, Kaiyi Wu, Ranxiang Yang, Jiahui Shen
  • Patent number: 11594889
    Abstract: Disclosed is an optimized energy interconnection system for an urban railway train in the technical field of urban railway transportation power supply, for addressing the technical problem that distribution of regenerative braking energy flows cannot be accurately determined. The system includes a DC intermediate bus and a multi-port flow controllable energy router. The multi-port flow controllable energy router can comprehensively control a source and a load connected in parallel on the DC intermediate bus and thus can accurately determine the distribution of regenerative braking energy flows, thereby forming a well-developed system for evaluating usage of the braking energy.
    Type: Grant
    Filed: November 2, 2018
    Date of Patent: February 28, 2023
    Assignee: CRRC ZHUZHOU ELECTRIC LOCOMOTIVE RESEARCH INSTITUTE CO., LTD.
    Inventors: Hongbo Li, Zhixue Zhang, Zihao Huang, Yilong Duan, Wenguang Luo, Wenqing Mei
  • Patent number: 11591650
    Abstract: The disclosed invention is related to a universal strand-specific protocol for the sequencing preparation of all classes of RNA. The protocol allows for sequencing for dozens to more than thousands of samples simultaneously. Specifically, the disclosed invention is a method for parallel sequencing target RNA from samples from multiple sources while maintaining source identification.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: February 28, 2023
    Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Alexander A. Shishkin, Mitchell Guttman, Christine F. Surka, Eric Lander
  • Patent number: 11592415
    Abstract: The present invention relates to an interdigitated microelectrode biosensor using the reaction between receptors and target biomaterials, the interdigitated microelectrode biosensor comprising: an insulating layer formed so as to cover all of the sensor formation area of a substrate; a first interdigitated microelectrode formed such that a plurality of first protruding electrodes are arranged in a comb shape on the insulating layer of the substrate; a second interdigitated microelectrode, facing the first interdigitated microelectrode and formed such that a plurality of second protruding electrodes are arranged in a comb shape on the insulating layer of the substrate such that the plurality of second protruding electrodes are arranged to respectively interdigitate with the plurality of first protruding electrodes formed at the first interdigitated microelectrode; and a plurality of receptors arranged in the space between the first and second interdigitated microelectrodes, which are arranged to interdigitate
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: February 28, 2023
    Assignee: Korea Institute of Science and Technology
    Inventors: Kyo Seon Hwang, Young Soo Kim, Jin Sik Kim, Yong Kyoung Yoo
  • Patent number: 11590285
    Abstract: Core annular flow is used to enable the subcutaneous delivery of a viscous fluid such as a protein therapeutic formulation. The high-viscosity fluid is surrounded by a low-viscosity fluid, and the low-viscosity fluid lubricates the passage of the high-viscosity fluid. This allows the use of protein formulations that have a higher concentration and a higher viscosity at comparatively reduced injection forces and reduced injection times. Several different embodiments of injection devices that provide core annular flow are described herein.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: February 28, 2023
    Assignee: Battelle Memorial Institute
    Inventors: Eric C. Scribben, Steven M. Risser, Amy M. Heintz, Jeffrey L. Ellis, John D. Clay, Timothy M. Blum
  • Patent number: 11594130
    Abstract: A warning system and method are provided. The warning system includes a plurality of sensing apparatuses and a server. The sensing apparatuses are used for sensing a driving trajectory of each of a plurality of two-wheeled vehicles. The server compares the driving trajectories with an accident hotspot list to determine whether at least one first driving trajectory matches an accident hotspot location, wherein the accident hotspot list is generated by a plurality of driving behavior events corresponding to each of the two-wheeled vehicles. The server generates a warning message to remind a first driver of a first two-wheeled vehicle corresponding to the at least one first driving trajectory when determining that the at least one first driving trajectory matches the accident hotspot location.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: February 28, 2023
    Assignee: INSTITUTE FOR INFORMATION INDUSTRY
    Inventors: Yao-Shun Yang, Hui-Tzu Huang, Jian-Ying Chen, Chuan-Chuan Wang
  • Patent number: 11591442
    Abstract: Disclosed are methods, compositions, reagents, systems, and kits to prepare materials with viscoelastic properties that respond to irradiation with light. Various embodiments show that bio-inspired histidine:transition metal ion complexes allow precise and tunable control over the viscoelastic properties of polymer networks containing these types of crosslinks pre and post-irradiation. These materials have the potential to aid biomedical materials scientists in the development of materials with specific stress-relaxing or energy-dissipating properties.
    Type: Grant
    Filed: May 17, 2018
    Date of Patent: February 28, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Niels Holten-Andersen, Scott Charles Grindy
  • Patent number: 11591615
    Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 1000 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cells of the retinal pigment epithelium of a gene when operatively linked to a nucleic acid sequence coding for said gene.
    Type: Grant
    Filed: November 28, 2018
    Date of Patent: February 28, 2023
    Assignee: Friedrich Miescher Institute for BioMedical Research
    Inventors: Josephine Juettner, Jacek Krol, Botond Roska
  • Patent number: 11589997
    Abstract: Described here are systems and methods for positioning a surgical implant, such as a glenoid component, or other medical device intra-operatively. In general, the systems and methods described in the present disclosure implement a computer vision system, which may be a structured light computer vision system, together with a suitable optical tracker as an accurate intra-operative tool for predicting post-operative implant position in surgical procedures.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: February 28, 2023
    Assignee: Sunnybrook Research Institute
    Inventors: David M. Burns, Cari M. Whyne, Normand Robert
  • Patent number: 11591228
    Abstract: A compound strontium fluoroborate, nonlinear optical crystal of strontium fluoroborate, preparation method thereof; the chemical formula of the compound is SrB5O7F3, its molecular weight is 310.67, and it is prepared by solid-state reaction; the chemical formula of the crystal is SrB5O7F3, its molecular weight is 310.67, the crystal is of the orthorhombic series, the space group is Ccm21, and the crystal cell parameters are=10.016(6) ?, b=8.654(6)(4) ?, c=8.103(5) ?, Z=4, and V=702.4(8) ?3. A SrB5O7F3 nonlinear optical crystal has uses in the preparation of a harmonic light output when doubling, tripling, quadrupling, quintupling, or sextupling the frequency of a 1064-nm fundamental-frequency light outputted by a Nd:YAG laser, or the generation of a deep-ultraviolet frequency doubling light output lower than 200 nm, or in the preparation of a frequency multiplier, upper or lower frequency converter, or an optical parametric oscillator.
    Type: Grant
    Filed: February 11, 2018
    Date of Patent: February 28, 2023
    Assignee: XINJIANG TECHNICAL INSTITUTE OF PHYSICS & CHEMISTRY, CHINESE ACADEMY OF SCIENCES
    Inventors: Shilie Pan, Miriding Mutailipu, Min Zhang
  • Patent number: 11593587
    Abstract: Provided are an object detection system and an object detection method. An object detection system may include a feature map extraction module configured to receive an image for object detection and extract a feature map having multiple resolutions for the image; a bounding box detection module configured to classify a bounding box by applying a first group of convolutional layers to the feature map, and predict the bounding box by applying a second group of convolutional layers to the feature map; and a mask generation module configured to generate a mask for the shape of the object in the bounding box using the feature map.
    Type: Grant
    Filed: May 20, 2021
    Date of Patent: February 28, 2023
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Youngwan Lee, Hyungil Kim, Jongyoul Park, Yu Seok Bae
  • Patent number: 11590406
    Abstract: A ski binding reduces a likelihood of injury to the anterior cruciate ligament (ACL) and the tibia is accomplished by absorption in the binding to limit loads transmitted through the boot-binding interface. Release based on an injury threshold includes a binding response tower attached to the ski and adapted for selective engagement with the ski, such that the binding response tower permits biased vertical and lateral horizontal displacement, prior to a release threshold. The binding is in communication with the boot heel and is adapted for slideable engagement in response to vertical and lateral forces exerted from the boot heel. The binding response tower adapted to disengage, or release upon reaching at least one a predetermined lateral displacement or a predetermined vertical displacement, such as when the boot heel is forced sufficiently sideways or upwards due to skier movement that would tend to cause an ACL injury.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: February 28, 2023
    Assignee: Worcester Polytechnic Institute
    Inventors: Jacob J. Billington, Jonathan D. Comden, Sean J. Regan, Thomas C. Roberti, Christopher A. Brown
  • Patent number: 11594656
    Abstract: Disclosed are a quantum light source and an optical communication apparatus including the same. The quantum light source device includes a vertical reflection layer disposed on a substrate, a lower electrode layer disposed on the vertical reflection layer, a horizontal reflection layer disposed on the lower electrode layer, a quantum light source disposed in the horizontal reflection layer, and an upper electrode layer disposed on the horizontal reflection layer.
    Type: Grant
    Filed: October 21, 2020
    Date of Patent: February 28, 2023
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Young-Ho Ko, Kap-Joong Kim, Byung-seok Choi, Won Seok Han
  • Patent number: 11590240
    Abstract: Disclosed herein are conjugated polymers comprising a polymer and an all-trans retinoic acid (ATRA) prodrug covalently bound to the polymer by a hydrolysable linker L or a pharmaceutically acceptable salt thereof, and methods of using same to treat certain disorders. In an embodiment, the conjugated polymer comprises poly (vinyl alcohol) covalently bound to ATRA through an ester linkage.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: February 28, 2023
    Assignee: Massachusetts Institute of Technology
    Inventors: Steven A. Castleberry, Mohiuddin A. Quadir, Paula T. Hammond
  • Patent number: 11591195
    Abstract: A swing arm restraint system for an automotive lift includes a movable carriage including a swing arm mounting portion. A first swing arm restraint housing is non-rotatably connected to the swing arm mounting portion, the first swing arm restraint housing including a first internal space. A first swing arm is pivotally connected to the swing arm mounting portion and is rotatable relative to the first swing arm restraint housing. A first restraint device is located in the first internal space and connected to the the swing arm restraint housing. A second restraint device is operably connected to the first swing arm such that the second restraint device rotates with the first swing arm relative to the first swing arm restraint housing.
    Type: Grant
    Filed: October 22, 2020
    Date of Patent: February 28, 2023
    Assignee: Automotive Lift Institute
    Inventors: Frederick G. Heath, Glenn D. Felpel
  • Patent number: 11591325
    Abstract: The present invention provides a 2-polysubstituted aromatic ring-pyrimidine derivative and an optical isomer thereof, or a pharmaceutically acceptable salt or solvate thereof, the compound, and an optical isomer thereof or a pharmaceutically thereof acceptable salts or solvates can be used in the preparation of anti-tumor drugs. The invention designs and synthesizes a series of novel small molecule Chk1 inhibitors by using N-substituted pyridin-2-aminopyrimidine obtained by structure-based virtual screening as a lead compound, and carries out Chk1 kinase inhibitory activity test. The experiment confirmed that said compounds possess potent anticancer activity, Chk1 kinase inhibitory activity, and are promising Chk1 inhibitors, and can be used as new cancer therapeutic drugs, which can be applied to treat solid tumors or hematologic tumors related to proliferative disease of human or animal.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: February 28, 2023
    Assignees: ZHEJIANG UNIVERSITY, SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Tao Liu, Jia Li, Yongzhou Hu, Yubo Zhou, Xiaowu Dong, Anhui Gao, Pinrao Song, Peipei Wang, Lexian Tong, Xiaobei Hu, Mingbo Su
  • Patent number: 11595263
    Abstract: Disclosed are a network control device and an operation method of the network control device for dynamically constructing an end-to-end virtual dedicated network slice based on a software-defined network (SDN) over the entire wired and wireless network section of a private network and a public network.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 28, 2023
    Assignees: TRENTO SYSTEMS, INC., KOREA INSTITUTE OF SCIENCE & TECHNOLOGY INFORMATION
    Inventors: Young Jae Kim, Dong Kyun Kim
  • Patent number: 11592532
    Abstract: In one embodiment, an integrated light transmission/reception optical system module includes a light receiving lens, a light source, and a light transmitting mirror. The light receiving lens receives light, concentrates the received light on a light detector disposed at a rear position, and has an optical path groove formed to be directed from a circumference to a central portion and formed to expose a front side. The light source outputs a pulse laser along the optical path groove from the circumference of the light receiving lens toward the central portion of the light receiving lens. The light transmitting mirror is disposed within the optical path groove, is located on a path of the pulse laser, and reflects in a front direction the pulse laser outputted from the light source. Other embodiments are also possible.
    Type: Grant
    Filed: July 2, 2019
    Date of Patent: February 28, 2023
    Assignee: KOREA ELECTRONICS TECHNOLOGY INSTITUTE
    Inventors: Hyunyong Choi, Hyun chang Cho
  • Patent number: 11591581
    Abstract: The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues or organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a SIN CRISPR complex, as well as methods for the design and use of such vectors. Also provided are methods of directing SIN CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: February 28, 2023
    Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, UNIVERSITY OF IOWA RESEARCH FOUNDATION
    Inventors: Feng Zhang, Beverly Davidson, Chie-Yu Lin, Edgardo Rodriguez
  • Patent number: 11595004
    Abstract: A highly linear time amplifier with power supply rejection. In a reset stage, the threshold value of an over-threshold detector is used for resetting an output node of an amplifier, to eliminate the impact of power supply voltage changes on the threshold value of the threshold detector. A node capacitor unit is charged under the control of an input clock signal. After completion of charging, the node capacitor unit is discharged under the control of a synchronous clock signal. The time amplification gain only depends on the proportion of the charge and discharge current, and the charging and discharging time are completely linear in principle, which eliminates the nonlinearity of the traditional time amplifier, and reduces the negative impact of threshold change on system performance.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: February 28, 2023
    Assignee: NO. 24 RESEARCH INSTITUTE OF CHINA ELECTRONICS TECHNOLOGY GROUP CORPORATION
    Inventors: Ting Li, Zhengbo Huang, Yong Zhang, Yabo Ni, Jian'an Wang, Dongbing Fu