Abstract: An object of the present invention is to establish means for providing a component vaccine which can elicit immunity to a non-structural protein. The present inventors have found that the object can be attained by providing a component vaccine containing an associated product containing a trimer and/or a hexamer of a molecular needle to which a non-structural protein of a pathogenic virus is attached.

Abstract: A method includes fitting a ML trained model to data features, the fitting generates complete data feature-set outputs that are associated with a first set of accuracy values, iteratively fitting, after an iterative removal of each data feature from the data feature-set, the ML trained model to subsets of the plurality of data features to determine respective reduced feature-set outputs, each subset lacks a different data feature of the plurality of data features, determining one or more of the reduced feature-set outputs as corresponding to a second set of accuracy values, designating the iteratively removed data features as accuracy-modifying data features, generating a first linear model, generating a second linear model based on one of the accuracy-modifying data features having a weight that is highest relative to respective different weights of the remaining ones of the accuracy-modifying data features, and identifying the second linear model as a generative model.

Abstract: An image encoding/decoding method and apparatus are provided. An image decoding method performed by an image decoding apparatus of the present invention may comprise decoding an indicator indicating whether or not partition information of a current block is derived from partition information of a corresponding block of the current block, obtaining the partition information of the current block based on the decoded indicator, and partitioning the current block based on the obtained partition information.

Abstract: The present disclosure provides improved genome editing compositions and methods for editing a human Wiskott-Aldrich syndrome gene. The disclosure further provides genome edited cells for the prevention, treatment, or amelioration of at least one symptom of WAS, including but not limited to, an immune system disorder, thrombocytopenia, eczema, X-linked thrombocytopenia (XLT), or X-linked neutropenia (XLN).

Abstract: An inkjet ink is provided. The inkjet ink includes a modified high-performance engineering plastic, a polar solvent, and a wetting agent. Additionally, a 3D printing method and a 3D printing object are provided. The modified high-performance engineering plastic includes modified polyphenylene sulfide, modified polyether-ether-ketone, modified polyether sulfone, modified polyphenylsulfone, or modified polysulfone.

Abstract: The present invention relates to a methods for high throughput screening of epitopes that are involved in T cell activation.

Abstract: Provided is a hologram printing method and apparatus using a hologram medium light efficiency map. A hologram printing method according to an embodiment emits a laser to a hologram medium, acquires an image by photographing light diffracted from the hologram medium, generates a light efficiency map of the hologram medium from the acquired image, and records hogels on the hologram medium by referring to the generated light efficiency maps of the hologram medium. Accordingly, light efficiency is measured on each hogel area, and hologram printing is performed by adjusting an intensity of a laser of each wavelength according to a hogel, so that uniformity of luminance and color of a hologram printing result can be enhanced.

Abstract: Disclosed herein are an apparatus and method for task-adaptive neural network retrieval based on meta-contrastive learning. The apparatus for task-adaptive neural network retrieval based on meta-contrastive learning includes: memory configured to store a database including a learning model pool consisting of a plurality of datasets and neural networks pre-trained on the datasets and also store a program for task-adaptive neural network retrieval based on meta-contrastive learning; and a controller configured to perform task-adaptive neural network retrieval based on meta-contrastive learning by executing the program. In this case, the controller learns a cross-modal latent space for datasets and neural networks trained on the datasets by calculating the similarity between each dataset and a neural network trained on the dataset while considering constraints included in any one task previously selected from the database, thereby retrieving an optimal neural network.

Abstract: Disclosed is an apparatus and method for processing a multichannel audio signal. A multichannel audio signal processing method may include: generating an N-channel audio signal of N channels by down-mixing an M-channel audio signal of M channels; and generating a stereo audio signal by performing binaural rendering of the N-channel audio signal.

Abstract: A micro device structure including a device and a fixed structure is provided. The device has an upper surface, a lower surface, and a first side surface. The lower surface is opposite to the upper surface. The first side surface connects the upper surface and the lower surface. The fixing structure includes a connecting portion and a first turning portion. The connecting portion extends at least from the upper surface of the device to the first side surface. The first turning portion is in contact to be connected with a first end of the connecting portion and extends outward from the first side surface to be away from the first side surface. The first end of the connecting portion is located on the first side surface between the upper surface and the lower surface. A display apparatus is also provided.

Abstract: A machine learning model-based essential gene identification method includes receiving, by an analysis apparatus, inputs of expression pattern information on genes of a specific cell; inputting, by the analysis apparatus, the expression pattern information to a machine learning model; and determining, by the analysis apparatus, whether a target gene from among the genes is essential in the survival of the cell on the basis of information output by the machine learning model.

Abstract: The preparation method for a nano composite coating having a shell-simulated multi-arch structure includes: constructing a discontinuous metal seed layer using a vacuum plating technology; and inducing the deposition of a continuous multi-arch structure layer utilizing the discontinuous metal seed layer, thereby realizing the controllable orientated growth of the nano composite coating having the shell-simulated multi-arch structure.

Abstract: Disclosed herein are a method for managing an access control list based on an automotive Ethernet and an apparatus for the same. The method includes analyzing a new access control rule that is input to a vehicle in which the automotive Ethernet is applied, searching for any one target unit to manage the new access control rule in consideration of at least one of a destination and an application target corresponding to the new access control rule, and storing the new access control rule by transmitting a storage request message corresponding to the new access control rule to the target unit.

Abstract: A wireless power transmission system and method are disclosed. The wireless power transmission system includes a plurality of wireless power transmitters configured to provide power to a plurality of wireless power receivers, and a controller configured to control the wireless power transmitters based on information of the wireless power receivers. The controller is configured to receive information of a wireless power receiver from the wireless power receiver, calculate a transmission parameter associated with a transmission efficiency of power to be provided to the wireless power receiver using the information of the wireless power receiver, and provide power to the wireless power receiver through the wireless power transmitters based on the transmission parameter.

Abstract: A polymer compound including a repeating unit represented by Formula: wherein R1, R2, R3, R4, a1, a2, and a11 in Formula 1 are as defined in the specification.

Abstract: A lithium ion conducting protective film is produced using a layer-by-layer assembly process. The lithium ion conducting protective film is assembled on a substrate by a sequential exposure of the substrate to a first poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the first side of the substrate, a graphene oxide (GO) layer on the first PEO layer, a second poly(ethylene oxide) (PEO) layer including a cross-linking silane component on the GO layer and a poly(acrylic acid) (PAA) layer on the second PEO layer. The film functions as a lithium ion conducting protective film that isolates the lithium anode from the positive electrochemistry of the cathode in a lithium-air battery, thereby preventing undesirable lithium dendrite growth.

Abstract: The present disclosure relates to a pharmaceutical composition for combination therapy for preventing or treating cancer, which contains a first pharmaceutical ingredient containing a drug conjugate wherein an anticancer agent is bound at one end of an amphiphilic peptide represented by SEQ ID NO 1 and a poloxamer; and a second pharmaceutical ingredient containing an anti-PD-L1 antibody; as active ingredients. The pharmaceutical composition significantly inhibits cancer growth in in-vivo experiments and exhibits an effect of significantly enhancing immunotherapeutic effect by activating immune cells in cancerous tissues. In particular, the pharmaceutical composition for combination therapy according to the present disclosure has superior tumor accumulation efficiency and selectivity as compared to existing anticancer agents, and is very stable with little toxicity to normal tissues other than cancerous tissues.

Abstract: A fine blanking device and method for forming a friction plate with friction material layers. The fine blanking device includes an upper die, a lower die, a guide mechanism, a punch and a counter punch. Upper and lower blank holders are respectively provided at outer circumferences of the punch and the counter punch. The upper and lower blank holders are respectively provided with a buffer mechanism. Friction material powders are sintered on both sides of the base sheet. The friction material layers are trimmed and planished by hot pressing. The base sheet with the friction material layers is fixed by the upper blank holder and the lower blank holder. A tooth profile with an absolute shear fractural surface is formed. The fixing indentation of the V-shaped structure of the friction material layers is cut off for obtaining a finished friction plate product with the friction material layers.

Abstract: The present invention relates to a heterocyclic amide inhibiting RIP1 kinase and the use thereof, and specifically, to a compound of formula I, its pharmaceutically acceptable salts, stereoisomers, enantiomers, diastereomers, atropisomers, optical isomers, racemates, polymorphs, solvates or isotopically labeled compounds, a pharmaceutical composition comprising the compound, and the pharmaceutical use thereof. The compound is particularly effective for treatment of diseases or disorders mediated by RIP1 kinase.

Abstract: A polymer composite formed from an epoxy based polymer and an amino-graphene. The epoxy based polymer forms a polymer matrix and the amino graphene is dispersed throughout the polymer matrix. Further, a graphene is functionalized with 3,5-dinitrophenyl groups to form functionalized graphene and one or more amine functional groups form Meisenheimer complexes with the functionalized graphene to form the amino-graphene. An associated method of making the polymer composite is also provided.