Abstract: One example described herein involves a system receiving task data and distribution criteria for a state space model from a client device. The task data can indicate a type of sequential Monte Carlo (SMC) task to be implemented. The distribution criteria can include an initial distribution, a transition distribution, and a measurement distribution for the state space model. The system can generate a set of program functions based on the task data and the distribution criteria. The system can then execute an SMC module to generate a distribution and a corresponding summary, where the SMC module is configured to call the set of program functions during execution of an SMC process and apply the results returned from the set of program functions in one or more subsequent steps of the SMC process. The system can then transmit an electronic communication to the client device indicating the distribution and its corresponding summary.

Abstract: Systems and methods for using quantitative ultrasound (“QUS”) techniques to generate imaging biomarkers that can be used to assess a prediction of tumor response to different chemotherapy treatment regimens are provided. For instance, the imaging biomarkers can be used to subtype tumors that have resistance to certain chemotherapy regimens prior to drug exposure. These imaging biomarkers can therefore be useful for predicting tumor response and for assessing the prognostic value of particular treatment regimens.

Abstract: A microscope objective is disclosed comprising; a lens; a housing; a lens holder that is arranged to couple the lens to the housing; a first conductor and a second conductor, the first conductor and the second conductor extending along a sidewall of the housing, the first conductor and the second conductor being arranged to form at least one loop that is that is disposed about at least a portion of a perimeter of a field of view of the lens.

Abstract: Disclosed are systems, methods, and structures for broadband phase shifting for quantitative phase microscopy (QPI) that advantageously allows for a greater useable wavelength range for QPI wherein either/both illumination paths and/or scatter paths: 1) propagate through a reflective objective; 2) become quantifiably phase-shifted utilizing broadband mirror surfaces; 3) attenuate the relatively bright illumination paths to maximize contrast; and 4) recombine at a sensor plane for quantitative analysis.

Abstract: Disclosed herein are peptide sequences capable of directing adeno-associated viruses (AAV) to target specific environments, for example the nervous system and the heart, in a subject. Also disclosed are AAVs having non-naturally occurring capsid proteins comprising the disclosed peptide sequences, and methods of using the AAVs to treat diseases.

Abstract: An anti-surge floating body, a seawater temperature measuring device and an integrated measuring system are provided. The floating material of the anti-surge floating body is in form of a closed loop, the floating material includes a first side close to a central axis of the floating material and a second side away from the central axis, and the wave-proof plate is connected with the second side of the floating material. The hollow space formed by the end-to-end connection of the floating material facilitates normal reception of solar radiation by the seawater, and avoids the influence on the temperature or other seawater parameters of the seawater below the floating material resulting from the floating material blocking solar radiation; moreover, the wave-proof plate can reduce the undulation and heaving of the waves of the seawater, and prevent turbulences of the seawater from affecting the seawater temperature or other seawater parameters.

Abstract: Coordinates of a point, representing a current pair of states of a vehicle, can be determined to be outside of a first curve. An interior of the first curve, representing a first region of operation of the vehicle, can be characterized by values of forces produced by tires being less than a saturation force. A distance between the point and a second curve can be determined. An interior of the second curve, representing a second region of operation of the vehicle, can be characterized by an ability of an operation of a control system to cause the vehicle to change from being operated in the current pair of states to being operated in the first region of operation. A manner in which the vehicle changes from being operated in the current pair of states to being operated in a different pair of states can be controlled based on the distance.

Abstract: A magnetically coupled piston pump includes a piston, a pump body, and a set of drive magnets. The piston includes a set of piston magnets. Each piston magnet has poles arranged along a longitudinal axis of the piston, and each piston magnet is arranged in the piston so that the orientation of the poles of each piston magnet is the opposite of the orientation of each adjacent piston magnet. The piston is disposed in and permitted to move within the pump body. The set of drive magnets is arranged outside the pump body. Each drive magnet corresponds to a piston magnet, has poles arranged along the longitudinal axis, and is arranged so that the orientation of the poles is opposite the orientation of the poles of the corresponding piston magnet. A drive unit is coupled to the drive magnets for moving the drive magnets along the longitudinal axis.

Abstract: A method of coating a carbon nanotube material with a solventless coating composition is described. The resulting coating has been shown to preserve the conductivity of the conductive layer and protect the conductive layer from the effects of subsequent coating compositions. Examples are shown in which the coating formulation comprises a polyol and an isocyanate. A layer material comprising a polyurethane coating on a carbon nanotube network layer is also described.

Abstract: A method and device for configuring a PDCCH time domain monitoring position are provided. The method includes: receiving PDCCH search space configuration signaling, wherein the PDCCH search space configuration signaling includes a PDCCH monitoring periodicity, a PDCCH monitoring offset, and indication signaling for indicating the starting position of a first symbol in which a PDCCH is located; and determining a time domain position for monitoring the PDCCH according to the PDCCH search space configuration signaling.

Abstract: The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity.

Abstract: Disclosed herein are a distributed system and a method for operating the distributed system. The method for operating a distributed system including a server and multiple clients includes acquiring, by a first client of the multiple clients, a lock on a shared resource using a first table of the server and a second table of the client, and releasing, by the first client, a lock on the shared resource using the first table and the second table, wherein the first table is a lock (DSLock) table for storing information about a distributed shared resource, and the second table is a data structure (DSLock_node) table for a lock request.

Abstract: The present disclosure provides a semiconductor device and a manufacturing method thereof, and an electronic device including the semiconductor device. The semiconductor device includes: a substrate; an active region including a first source/drain region, a channel region and a second source/drain region stacked sequentially on the substrate and adjacent to each other; a gate stack formed around an outer periphery of the channel region; and spacers formed around the outer periphery of the channel region, respectively between the gate stack and the first source/drain region and between the gate stack and the second source/drain region; wherein the spacers each have a thickness varying in a direction parallel to a top surface of the substrate.

Abstract: A thermoelectric material includes a parent phase in which an MgSiSn alloy is a main component, a void formed in the parent phase, and a silicon layer that is formed on at least a wall surface of the void and that includes silicon as a main component. The thermoelectric material further includes MgO in an amount of 1.0 wt. % or more and 20.0 wt. % or less. The silicon layer includes amorphous Si, or amorphous Si and nanosized Si crystals, and the parent phase includes a region in which the composition ratio of the Si of the chemical composition of the MgSiSn alloy is higher than in the other regions and a region in which the composition ratio of the Sn of the chemical composition of the MgSiSn alloy is higher than in the other regions. With these configurations, the thermoelectric material realizes both lower thermal conductivity and lower electrical resistivity.

Abstract: The invention relates to methods of identifying compounds that modulate mTORC1 activity in a cell by modulating the activity of SAMTOR, as well as to the use of such identified compounds in the modulation of mTORC1 and the treatment of diseases and conditions characterized by aberrant mTORC1 activity.

Abstract: A quantum key distribution device is provided with an encoding unit which encodes an optical pulse train; an intensity modulating unit which subjects the encoded optical pulse train to N (where N is an integer at least equal to 3) types of intensity modulation having mutually different intensities, with different timings; and a first key distillation processing unit which generates an encryption key on the basis of a data sequence obtained by removing data obtained from an optical pulse having a specific modulation pattern from a data sequence used by the encoding unit and the intensity modulating unit.

Abstract: There is described herein a method of prognosing and/or predicting disease progression and/or in subject with prostate cancer, the method comprising: a) providing a sample containing mitochondrial genetic material from prostate cancer cells; b) sequencing the mitochondrial genetic material with respect to at least 1 patient biomarker selected from CSB1, OHR, ATP8 and HV1 (hypervariable region 1); c) comparing the sequence of the patient biomarkers to control or reference biomarkers to determine mitochondrial single nucleotide variations (mtSNVs); and d) determining the a prostate cancer prognosis; wherein a relatively worse outcome is associated with the presence of mtSNVs in CSB1, OHR, ATP8 and a relatively better outcome is associated with the presence of mtSNVs in HV1.

Abstract: In one example, a system can execute a first machine-learning model to determine an overall classification for a textual dataset. The system can also determine classification scores indicating the level of influence that each token in the textual dataset had on the overall classification. The system can select a first subset of the tokens based on their classification scores. The system can also execute a second machine-learning model to determine probabilities that the textual dataset falls into various categories. The system can determine category scores indicating the level of influence that each token had on a most-likely category determination. The system can select a second subset of the tokens based on their category scores. The system can then generate a first visualization depicting the first subset of tokens color-coded to indicate their classification scores and a second visualization depicting the second subset of tokens color-coded to indicate their category scores.

Abstract: The present invention relates a wireless communication method and a wireless communication terminal for supporting a spatial reuse operation of an overlapping basic service set to efficiently use a wireless resource. To this end, provided are a base wireless communication terminal including: a processor; and a communication unit, wherein the processor receives a PHY protocol data unit (PPDU) through the communication unit, determines whether the PPDU contains an intra-BSS frame or contains an inter-BSS frame based on preamble information of the PPDU, and performs either a first operation or a second operation distinct from each other according to a determination result and a wireless communication method using the same.

Abstract: A base station of a wireless communication system is disclosed. The base station of wireless communication includes a communication module and a processor. The processor is configured to receive a grant for scheduling a plurality of uplink transmissions from the base station, and when the UE attempts to a first fixed duration-based channel access for a first transmission which is one of the plurality of uplink transmission and fails in the first fixed duration-based channel access, attempt to a second fixed duration-based channel access for a second transmission which is a transmission following the first transmission.