Patents Assigned to Ion Torrent Systems Incorporated
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Publication number: 20100301398Abstract: Methods and apparatus relating to FET arrays including large FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.Type: ApplicationFiled: May 29, 2009Publication date: December 2, 2010Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, James M. Bustillo, Mark J. Milgrew, Jonathan C. Schultz, David Marran, Todd M. Rearick, Kim L. Johnson
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Publication number: 20100282617Abstract: Methods and apparatuses relating to large scale FET arrays for analyte detection and measurement are provided. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes.Type: ApplicationFiled: June 26, 2009Publication date: November 11, 2010Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz
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Publication number: 20100197507Abstract: Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis.Type: ApplicationFiled: March 10, 2010Publication date: August 5, 2010Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz, Kim L. Johnson, James Bustillo
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Publication number: 20100188073Abstract: Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis.Type: ApplicationFiled: January 22, 2010Publication date: July 29, 2010Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz, Kim L. Johnson, James Bustillo
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Publication number: 20100137143Abstract: Methods and apparatus relating to FET arrays including large FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.Type: ApplicationFiled: May 29, 2009Publication date: June 3, 2010Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz, John F. Davidson, Antoine M. van Oijen, John H. Leamon, Martin Huber
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Publication number: 20100035252Abstract: The invention provides apparatuses and methods of use thereof for sequencing nucleic acids subjected to a force, and thus considered under tension. The methods may employ but are not dependent upon incorporation of extrinsically detectably labeled nucleotides.Type: ApplicationFiled: December 31, 2008Publication date: February 11, 2010Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, John H. Leamon, John F. Davidson, Antoine M. Van Oijen, Wolfgang Hinz, Melville Davey, Bradley Hann, Jonathan Schultz
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Publication number: 20090127589Abstract: Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis.Type: ApplicationFiled: December 14, 2007Publication date: May 21, 2009Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz, Kim L. Johnson, James Bustillo
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Publication number: 20090026082Abstract: Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis.Type: ApplicationFiled: December 17, 2007Publication date: January 29, 2009Applicant: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz
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Patent number: D595990Type: GrantFiled: September 24, 2008Date of Patent: July 14, 2009Assignee: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz
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Patent number: D596440Type: GrantFiled: September 24, 2008Date of Patent: July 21, 2009Assignee: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz
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Patent number: D602784Type: GrantFiled: September 24, 2008Date of Patent: October 27, 2009Assignee: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz
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Patent number: D602785Type: GrantFiled: September 24, 2008Date of Patent: October 27, 2009Assignee: Ion Torrent Systems IncorporatedInventors: Jonathan M. Rothberg, Wolfgang Hinz