Patents Assigned to Iowa State University Research Foundation
  • Glycine max resistance gene(s) and use thereof to engineer plants with broad-spectrum resistance to fungal pathogens and pests
    Patent number: 10087461
    Abstract: The present invention relates to a method of increasing plant resistance to plant pathogens, particularly Sudden Death Syndrome in soybean against Fusarium virguliforme, through the use of Fusarium resistance nucleic acid molecules isolated from Glycine max and Fusarium virguliforme. In these plants, at least one heterologous Fusarium resistance protein is introduced in comparison to the wild-type plants to confer resistance to plant pathogens. The invention relates to transgenic plants and/or plant cells having increased resistance to plant pathogens, to expression vectors, transformed plants and plant cells as well as the use of such plants in a plant breeding program.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: October 2, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Madan K. Bhattacharyya, Micheline Ngaki
  • Polyisocyanates from fused bicyclic polyols and polyurethanes therefrom
    Patent number: 10081638
    Abstract: The present invention is directed to polyisocyanates and polyurethanes derived therefrom. In various embodiments, the present invention provides polyisocyanates, methods of making the polyisocyanates from fused bicyclic alcohols, polyurethanes, and methods of making the polyurethanes from the polyisocyanates.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: September 25, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Jason Shih-Hao Chen, Michael Richard Kessler, Michael Dennis Zenner
  • Aziridinated triglycerides and polymers formed therefrom
    Patent number: 10077257
    Abstract: Various embodiments disclosed relate to aziridinated triglycerides and polymers formed therefrom. In various embodiments, the present invention provides an aziridinated triglyceride having the structure described herein. In various embodiments, the present invention provides a method of making the aziridinated triglyceride, a method of crosslinking the aziridinated triglyceride to form a polymer, the polymer formed from the aziridinated triglyceride, a triglyceride with at least one pendent unsaturated group that can be used to form the aziridinated triglyceride, and a method of making the triglyceride having at least one pendent unsaturated group.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: September 18, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ruqi Chen, Jason Shih-Hao Chen, Chaoqun Zhang, Michael Richard Kessler
  • Low RF-band impedance spectroscopy based sensor for in-situ, wireless soil sensing
    Patent number: 10073074
    Abstract: A soil sensor includes a housing, an antenna disposed within the housing, a measurement circuit disposed within the housing and operatively connected to the antenna, the circuit configured to measure impedance of soil at a plurality of different frequencies using the antenna as a sensor electrode, and a wireless interface disposed within the housing and operatively connected to the antenna and configured for wireless communications over the antenna at its communications frequency.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: September 11, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ratnesh Kumar, Robert J. Weber, Gunjan Pandey
  • Poly(acrylated polyol) and method for making and using thereof as asphalt rubber modifiers, adhesive, fracking additives, or fracking fluids
    Patent number: 10066051
    Abstract: The present invention relates to a thermoplastic copolymer, block copolymer, and statistical copolymer comprising plural acrylated polyol monomeric units having different degrees of acrylation of hydroxyl groups. The acrylated polyol monomeric units have an average degree of acrylation greater than 1 and less than the number of the hydroxyl groups of the polyol. The present invention also relates to a method of making the thermoplastic copolymer, block copolymer, and statistical copolymer, and using them in various applications, such as asphalt rubber modifiers, adhesives, or an additive in a fracking fluid for oil fracking.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: September 4, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Eric W. Cochran, R. Christopher Williams, Nacu Hernandez, Elvira Joana Ferreira Peralta, Michael John Forrester
  • Automatic insulin delivery system
    Patent number: 10064994
    Abstract: A system and method for automatically administering insulin based on a feedforward control. The automatic insulin delivery system may include a computing device comprising a processor, machine readable non-transitory media which stores the coupled-model of the invention, and a monitoring system. The machine readable transitory media may be configured to receive one or more inputs and the coupled-model may utilize a feedforward control to parameterize the inputs and generate an output that can be translated to a type and amount of insulin to be administered by the system. The input(s) received by the machine readable non-transitory media may be created by a user or received from one or more sensors. The method may include providing a model that is stored on a machine readable non-transitory media and administering insulin based on the output provided by the model.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: September 4, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Derrick K. Rollins, Sr.
  • nonhost resistance gene(s) and use thereof to engineer disease resistant plants
    Patent number: 10045499
    Abstract: The present invention relates to a method of increasing resistance against plant pathogens, particularly Phytophthora and Fusarium virguliforme in transgenic plants and/or plant cells, through the use of non host resistance nucleic acid molecules isolated from Arabidopsis. In these plants, at least one nonhost Arabidopsis resistance protein is introduced in comparison to the wild-type plants to confer resistance to plant pathogens. The invention relates to transgenic plants and/or plant cells having an increased resistance against plant pathogens particularly Phytophthora and Fusarium virguliforme to expression vectors, transformed plants and plant cells as well as the use of such plants in a plant breeding program.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: August 14, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Madan K. Bhattacharyya, Rishi Sumit, Binod B. Sahu
  • ORGANIC PHOTOVOLTAIC DEVICE WITH FERROELECTRIC DIPOLE AND METHOD OF MAKING SAME
    Publication number: 20180219158
    Abstract: A method of fabricating an organic photovoltaic device. The method includes providing a first electrode which by applying a layer of conductive material onto a transparent substrate. The conductive material forms the first electrode. The method also includes placing an active layer of organic photovoltaic material on top of the first electrode. The active layer is configured to convert photonic energy into electrical energy. Placing an active layer of organic photovoltaic material includes placing an active layer of organic photovoltaic material having ferroelectric dipoles dispersed therein. The method further includes applying a second electrode on top of the active layer of organic photovoltaic material.
    Type: Application
    Filed: March 26, 2018
    Publication date: August 2, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Kanwar Singh Nalwa, Sumit Chaudhary
  • Organic photovoltaic device with ferroelectric dipole and method of making same
    Patent number: 10038142
    Abstract: A method of fabricating an organic photovoltaic device. The method includes providing a first electrode which by applying a layer of conductive material onto a transparent substrate. The conductive material forms the first electrode. The method also includes placing an active layer of organic photovoltaic material on top of the first electrode. The active layer is configured to convert photonic energy into electrical energy. Placing an active layer of organic photovoltaic material includes placing an active layer of organic photovoltaic material having ferroelectric dipoles dispersed therein. The method further includes applying a second electrode on top of the active layer of organic photovoltaic material.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: July 31, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Kanwar Singh Nalwa, Sumit Chaudhary
  • Separation of terbium(III,IV) oxide
    Patent number: 10029920
    Abstract: Various embodiments relate to separation of terbium(III,IV) oxide. In various embodiments, present invention provides a method of separating terbium(III,IV) oxide from a composition. The method can include contacting a composition including terbium(III,IV) oxide and one or more other trivalent rare earth oxides with a liquid including acetic acid to form a mixture. The contacting can be effective to dissolve at least some of the one or more other trivalent rare earth oxides into the liquid. The method can include separating undissolved terbium(III,IV) oxide from the mixture, to provide separated terbium(III,IV) oxide.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: July 24, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Anja-Verena Mudring, Denis Prodius
  • SOLVENT-FREE, SOLID PHASE SYNTHESIS OF HYBRID LEAD HALIDE PEROVSKITES WITH SUPERIOR PURITY
    Publication number: 20180204682
    Abstract: A method of synthesizing a mixed-halide perovskite is disclosed herein. The method includes the steps of mixing a first single-halide perovskite and a second single-halide perovskite to form a solid phase mixture and heating the solid phase mixture at a temperature below a first decomposition temperature of the first single-halide perovskite and below a second decomposition temperature of the second single-halide perovskite for a time sufficient to form the mixed-halide perovskite. During the mixing, the first and second single-halide perovskite are both in the solid phase. A mixed-halide perovskite made according to the method is also disclosed herein. The mixed-halide perovskite is free of amorphous and/or semicrystalline phases. The mixed-halide perovskite can be utilized in a photovoltaic cell in a solar panel.
    Type: Application
    Filed: December 26, 2017
    Publication date: July 19, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Javier Vela-Becerra, Bryan A. Rosales
  • VANILLIN METHACRYLATES AND POLYMERS THEREFROM
    Publication number: 20180201703
    Abstract: Vanillin and vanillyl alcohol were modified into methacrylated derivatives. The structures of vanillin-based monomers were characterized by NMR and FTIR. Renewable polymers were prepared from these vanillin-based monomers. The effects of structure and functionality of the vanillin-based monomers on the thermo-mechanical properties of the resulting polymers were investigated and discussed. Polymers from methacrylated vanillyl alcohol (MVA) demonstrated greater storage moduli, higher glass transition temperatures, and thermal resistance than those from methacrylated vanillin (MV) because of the different functionalities of their monomers.
    Type: Application
    Filed: July 7, 2016
    Publication date: July 19, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Michael Richard Kessler, Chaoqun Zhang
  • Animal model protocol, diagnostic, therapeutic and vaccine against digital dermatitis
    Patent number: 10022458
    Abstract: Applicants have discovered a novel induction method for inducing digital dermatitis lesions consistent with the natural disease process. Applicants have prepared a consortium including a macerated tissue culture that may be used in the method as well as a novel inoculation procedure. The consortia of microbes includes isolates of Treponema phagedenis, Porphorymonas, and Bacteroides and the invention includes use of these novel isolates in preventing and treating digital dermatitis. The invention can be used to screen, test or compare the relative efficacy of various drugs and biologics for use in treatment or control of digital dermatitis.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: July 17, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Paul Joseph Plummer, Adam Krull, Jan Shearer, Patrick Gorden
  • Systems and methods for recognizing, classifying, recalling and analyzing information utilizing SSM sequence models
    Patent number: 10007662
    Abstract: A biologically-inspired model for sequence representation, method of construction and application of such models, and systems incorporating same are provided. The model captures the statistical nature of sequences and uses that for sequence encoding, recognition, and recall. The model can be trained in real time, has few tunable parameters, and is highly parallelizable, which ensures that it can scale up to very large problems. Applications of the model to word and speech recognition, machine leaning, robotics, computational bioinformatics, genetics datasets, and other sequence processing pipelines are provided.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: June 26, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Alexander Stoytchev, Volodymyr Sukhoy
  • Biodegradable fertilizer
    Patent number: 9988318
    Abstract: This invention relates to bio-renewable fertilizer compositions and methods of making and using the bio-renewable fertilizer compositions. In particular, the fertilizer compositions include biodegradable nutrient carriers, which have naturally derived, bio-renewable nitrogen content. The fertilizer compositions also contain biodegradable stabilizer.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: June 5, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: James Schrader, William Graves, Jr., David Grewell
  • SYSTEMS AND METHODS FOR RECOGNIZING, CLASSIFYING, RECALLING AND ANALYZING INFORMATION UTILIZING SSM SEQUENCE MODELS
    Publication number: 20180150457
    Abstract: A biologically-inspired model for sequence representation, method of construction and application of such models, and systems incorporating same are provided. The model captures the statistical nature of sequences and uses that for sequence encoding, recognition, and recall. The model can be trained in real time, has few tunable parameters, and is highly parallelizable, which ensures that it can scale up to very large problems. Applications of the model to word and speech recognition, machine leaning, robotics, computational bioinformatics, genetics datasets, and other sequence processing pipelines are provided.
    Type: Application
    Filed: January 9, 2015
    Publication date: May 31, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Alexander Stoytchev, Volodymyr Sukhoy
  • CHIMERIC INFECTIOUS DNA CLONES, CHIMERIC PORCINE CIRCOVIRUSES AND USES THEREOF
    Publication number: 20180147275
    Abstract: The present invention relates to infectious DNA clones, infectious chimeric DNA clones of porcine circovirus (PCV), vaccines and means of protecting pigs against viral infection or postweaning multisystemic wasting syndrome (PMWS) caused by PCV2. The new chimeric infectious DNA clone and its derived, avirulent chimeric virus are constructed from the nonpathogenic PCV1 in which the immunogenic ORF gene of the pathogenic PCV2 replaces a gene of the nonpathogenic PCV1, preferably in the same position. The chimeric virus advantageously retains the nonpathogenic phenotype of PCV1 but elicits specific immune responses against the pathogenic PCV2. The invention further embraces the immunogenic polypeptide expression products. In addition, the invention encompasses two mutations in the PCV2 immunogenic capsid gene and protein, and the introduction of the ORF2 mutations in the chimeric clones.
    Type: Application
    Filed: January 19, 2018
    Publication date: May 31, 2018
    Applicants: Virginia Tech Intellectual Properties, Inc., Iowa State University Research Foundation, Inc.
    Inventors: Xiang-Jin Meng, Martijn Fenaux, Patrick G. Halbur
  • Atomizer for improved ultra-fine powder production
    Patent number: 9981315
    Abstract: A concentric ring gas atomization nozzle with isolated gas supply manifolds is provided for manipulating the close-coupled atomization gas structure to improve the yield of atomized powders.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: May 29, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Joel R. Rieken, Andrew J. Heidloff, Iver E. Anderson
  • Organic photovoltaic device with ferroelectric dipole and method of making same
    Patent number: 9966533
    Abstract: A method of fabricating an organic photovoltaic device. The method includes providing a first electrode which by applying a layer of conductive material onto a transparent substrate. The conductive material forms the first electrode. The method also includes placing an active layer of organic photovoltaic material on top of the first electrode. The active layer is configured to convert photonic energy into electrical energy. Placing an active layer of organic photovoltaic material includes placing an active layer of organic photovoltaic material having ferroelectric dipoles dispersed therein. The method further includes applying a second electrode on top of the active layer of organic photovoltaic material.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: May 8, 2018
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Kanwar Singh Nalwa, Sumit Chaudhary
  • QUADRUPLE BUTTERFLY COIL
    Publication number: 20180117352
    Abstract: Provided herein are embodiments of a Quadruple Butterfly Coil (QBC) configuration having enhanced focality for stimulation of specific areas of a brain for therapeutic treatment. Finite element simulations were conducted for the QBC, the QBC with a single shield, and the QBC with a double shield. The stimulation profiles for these coil configurations were assessed with 50 anatomically realistic MRI derived head models. The coils were positioned on the vertex and the scalp over the dorsolateral prefrontal cortex to stimulate the brain. Computer modeling of the coils was performed to determine volume of stimulation, maximum electric field, location of maximum electric field, and area of stimulation across all 50 head models for both coils.
    Type: Application
    Filed: October 26, 2017
    Publication date: May 3, 2018
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: Priyam Rastogi, Erik Gordon Lee, Magundappa Ravi L. Hadimani, David C. Jiles