Patents Assigned to Iowa State University Research Foundation
  • Aziridinated triglycerides and polymers formed therefrom
    Patent number: 10501448
    Abstract: Various embodiments disclosed relate to aziridinated triglycerides and polymers formed therefrom. In various embodiments, the present invention provides an aziridinated triglyceride having the structure described herein. In various embodiments, the present invention provides a method of making the aziridinated triglyceride, a method of crosslinking the aziridinated triglyceride to form a polymer, the polymer formed from the aziridinated triglyceride, a triglyceride with at least one pendent unsaturated group that can be used to form the aziridinated triglyceride, and a method of making the triglyceride having at least one pendent unsaturated group.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: December 10, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ruqi Chen, Jason Shih-Hao Chen, Chaoqun Zhang, Michael Richard Kessler
  • INFLUENZA NANOVACCINE
    Publication number: 20190365887
    Abstract: Immunogenic compositions and methods of using them include a biodegradable or bioerodible polyanhydride nanoparticle comprising 1,8-bis(p-carboxyphenoxy)-3,6-dioxaoctane (CPTEG) and 1,6-bis(p-carboxyphenoxy)hexane (CPH) copolymers, an immunogenic protein of an Influenza Virus and an adjuvant entrapped within an interior of the nanoparticle, and an excipient. The immunogenic composition may be administered to a subject to confer both local and systemic immunity to the Influenza Virus.
    Type: Application
    Filed: March 29, 2019
    Publication date: December 5, 2019
    Applicants: Iowa State University Research Foundation, Inc., University of Iowa Research Foundation
    Inventors: Balaji NARASIMHAN, Kathleen A. Ross, Kevin L. Legge, Thomas J. Waldschmidt
  • Alkylated photoremovable protecting groups and uses thereof
    Patent number: 10493153
    Abstract: The invention relates to a method for photoreleasing a moiety G from a compound of the formula A-G. The methods of the present invention comprise irradiating a composition comprising the compound of the formula A-G at a wavelength of >500 nm, so as to photorelease the moiety G from the moiety A; wherein the moiety A comprises a chromophore and the moiety G comprises an organic compound.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: December 3, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Arthur Henry Winter
  • Baler mass flow sensing assembly and method
    Patent number: 10477775
    Abstract: A crop sensing system for a baler includes a compression system for forming a bale and a feed system for picking up crop from a surface and conveying the crop to the compression system. The crop sensing system includes a sensor arrangement having at least one sensor being coupled to at least one of the compression system or the feed system, wherein the at least one sensor generates a signal corresponding to a crop load on the at least one of the compression system or the feed system. The crop sensing system includes a control unit configured to receive the signal from the sensor arrangement and calculate crop mass data based on at least the signal.
    Type: Grant
    Filed: September 15, 2015
    Date of Patent: November 19, 2019
    Assignees: DEERE & COMPANY, IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric R. Lang, Jeffrey Askey
  • High-throughput large-scale plant phenotyping instrumentation
    Patent number: 10470379
    Abstract: Systems, methods, and apparatus for large scale, high throughput phenotyping of items including plants to derive environment/genetics correlations based on controlled variation of environment. Spatial and temporal resolution is improved by an integrated system that can use space efficiently yet concurrently process a large number of replicates but in varying environments. This is accomplished by using an array of miniature greenhouses, each in communication with one or more generators or regulators of an environmental factor that can be independently supplied and controlled to each miniature greenhouse. The controller also controls acquisition of data from each greenhouse as well as processing of that data into phenomic/genomic correlations.
    Type: Grant
    Filed: June 12, 2015
    Date of Patent: November 12, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Liang Dong, Huawei Jiang, Maneesha Aluru
  • Methods and compositions for prevention of feedlot bovine respiratory disease
    Patent number: 10463656
    Abstract: Methods for preventing feedlot bovine respiratory diseases employing an anti-inflammatory drug rupatadine are disclosed. Compositions are further disclosed. Beneficially, the methods and compositions provide safe and cost-effective management of a costly disease.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: November 5, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Steven Alan Carlson, Timothy L. Day
  • Electrochemical isomerization of muconic acid
    Patent number: 10465043
    Abstract: Various embodiments disclosed relate to electrochemical isomerization of muconic acid. In various embodiments, the present invention provides a method to prepare trans,trans-muconic acid. The method can include passing current through a catalytic cathode in a reactor including an aqueous acidic solution including cis,trans-muconic acid, a supporting electrolyte, and an anode, so as to isomerize the cis,trans-muconic acid to yield a product including trans trans-muconic acid.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: November 5, 2019
    Assignee: Iowa State University Research Foundation
    Inventors: Jean-Philippe Tessonnier, John Edward Matthiesen, Toni Pfennig, Brent Shanks, Jack M. Carraher
  • Fatty acid ester-based wax compositions and methods of making thereof
    Patent number: 10457892
    Abstract: This invention relates to a wax composition comprising one or more fatty acid diester compounds having the formula of R1 and R2 are each independently a substituted or unsubstituted C4 to C50 alkyl or aryl; and n1 is an integer from 2 to 10. This invention also relates to a wax composition comprising: a) one or more fatty acid monoester or diester compounds having the formula of: and b) one or more hydroxylated fatty acid diester compounds having the formula of In these formulae, R is H or COR1?; R1? and R2? are each independently a substituted or unsubstituted C4 to C50 alkyl or aryl; n2 is an integer from 2 to 24; m is an integer from 2 to 12; and .(OH)m represents 2 to 12 hydroxyl groups substituting for 2 to 12 hydrogen atoms in the alkyl groups R1? and/or R2?. Uses of the compositions are also disclosed.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: October 29, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Tong Wang, Tao Fei
  • Miniaturized continuous-flow fermenting apparatus
    Patent number: 10457904
    Abstract: A system, method, and apparatus for the fermentation of a beverage by use of continuous flow is provided. The fermented beverage can be any of a wine, beer, mead, ale, soda, cider, or other. The invention provides for small-scale fermentation that can be done in a much shorter time than previous batch fermentations. The small-scale and shortened time allows for variables to be introduced and tested to produce new varieties, flavors, qualities, and other combinations that are inputs of the fermented beverage.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: October 29, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Daniel Attinger, Liang Dong, Yuncong Chen
  • Methods of producing solid fuel using low ash, low sulfur coal replacement from fast pyrolysis of biomass
    Patent number: 10457882
    Abstract: The present invention is directed to a method of producing a solid fuel which includes providing a bio-oil and thermally curing the bio-oil to form a carbonaceous solid. The present invention is also directed to a method of producing a solid fuel which includes providing a bio-oil; subjecting the bio-oil to an extraction procedure with an aqueous liquid to produce a concentrated pyrolytic sugar-containing extract and a water insoluble raffinate comprising a lignin-derived phenolic oil; and thermally curing the phenolic oil to form a carbonaceous solid.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: October 29, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Robert C. Brown, Marjorie Rover, Andrew J. Friend, Ryan G. Smith
  • Lubricated mechanical polishing
    Patent number: 10442055
    Abstract: A lubricated mechanical polishing (LMP) process is provided that uses hard nanoparticles of less than 5 nm diameter dispersed in a fluid lubricant as a polishing slurry to produce an ultra-smooth surface on a hard metallic or non-metallic substrate with a sub-nanometer surface roughness substantially less than that produced by silica chemical mechanical polishing.
    Type: Grant
    Filed: January 31, 2017
    Date of Patent: October 15, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ludovico Cademartiri, Briane Caroline Montoya
  • Fuel-cell system and method of generating energy from crude fuel
    Patent number: 10446852
    Abstract: The present invention relates to a fuel-cell system. This system includes an anode electrode; a cathode electrode; a separator positioned between the anode electrode and the cathode electrode, wherein the separator is not an ion exchange membrane; an anode catalyst; and a cathode catalyst, wherein the cathode catalyst is a non-precious metal catalyst or metal-free catalyst. The present invention also relates to a method of generating energy from crude fuel. This method involves providing a fuel-cell system and contacting the fuel-cell system with a crude fuel under conditions effective to generate energy from the crude fuel.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: October 15, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Wenzhen Li, Neeva Benipal, Ji Qi, Yang Qiu
  • Closed loop 3D printing
    Patent number: 10442118
    Abstract: To better control part quality of 3D printed parts, the temperature of an extruder filament using a secondary heat source is provided. A heat source, such as an infrared heat source, can be used to heat the filament of a 3D printer to the optimum temperature that will enhance welding of the filament to a substrate that it is being printed on or to. Such an optimum temperature can be based upon, in part, the temperature of the substrate. A controller or other intelligent control can be used to receive temperature readings of the substrate and/or filament and then can adjust the temperature of the heating source to optimize the temperature of the filament to better combine the filament to the substrate.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 15, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: David Grewell
  • Pb-free Sn—Ag—Cu—Al or Sn—Cu—Al solder
    Patent number: 10442037
    Abstract: A solder alloy includes Sn, optional Ag, Cu, and Al wherein the alloy composition is controlled to provide a strong, impact-and thermal aging-resistant solder joint that has beneficial microstructural features and is substantially devoid of Ag3Sn blades.
    Type: Grant
    Filed: February 24, 2015
    Date of Patent: October 15, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Iver E. Anderson, Joel L. Harringa, Adam J. Boesenberg
  • Transmammary delivery of cyclooxygenase-2 inhibitors for analgesia in neonates
    Patent number: 10434083
    Abstract: Methods for transmammary administration of an analgesic to offspring swine are disclosed, which are useful for mitigating, inhibiting, and/or reducing pain in offspring swine prior to undergoing processing procedures that would cause or result in pain. The methods generally comprise administering, via injection, a cyclooxygenase-2 inhibitor class analgesic directly to a lactating female swine. The analgesic is passed indirectly to the offspring swine through the milk of the treated lactating female swine and has beneficial effects, including increases in weight gain, performance, and decreases in pain. A single dosage form injected into the lactating female is suitable for achieving indirect therapeutically effective levels of the cyclooxygenase-2 inhibitor class analgesic in the milk for the offspring.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: October 8, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventor: Johann F. Coetzee
  • Method for producing La/Ce/MM/Y base alloys, resulting alloys, and battery electrodes
    Patent number: 10435770
    Abstract: A carbothermic reduction method is provided for reducing a La-, Ce-, MM-, and/or Y-containing oxide in the presence of carbon and a source of a reactant element comprising Si, Ge, Sn, Pb, As, Sb, Bi, and/or P to form an intermediate alloy material including a majority of La, Ce, MM, and/or Y and a minor amount of the reactant element. The intermediate material is useful as a master alloy for in making negative electrode materials for a metal hydride battery, as hydrogen storage alloys, as master alloy additive for addition to a melt of commercial Mg and Al alloys, steels, cast irons, and superalloys; or in reducing Sm2O3 to Sm metal for use in Sm—Co permanent magnets.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: October 8, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Karl A. Gschneidner, Jr., Frederick A. Schmidt
  • Baler information system and method
    Patent number: 10436913
    Abstract: A bale information system includes a baling machine configured to process a material into a bale, the baling machine including a sensor configured to measure a release of the bale from the baling machine, a global positioning system receiver in operable communication with the baling machine, and a data storage system operable to receive and store data from the global positioning system receiver.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: October 8, 2019
    Assignees: DEERE & COMPANY, IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Eric R. Lang, Walter M. Schlesser, Jeffrey Askey
  • Materials and method for increasing a plant's resistance to stress
    Patent number: 10415053
    Abstract: Method of increasing resistance to a pathogen or a pest in a plant comprising introducing into the plant and expressing therein a polynucleotide comprising a nucleotide sequence encoding a Qua-Quine Starch (QQS) polypeptide; method of producing a plant with increased resistance to a pathogen or a pest comprising crossing a plant obtained in accordance with the above method with a second plant to produce progeny plants and selecting progeny plants with increased resistance to a pathogen or a pest; a plant with increased resistance to a pathogen or a pest; a seed of the plant; a hybrid of the plant; and a seed of the hybrid plant.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: September 17, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Ling Li, Eve Syrkin Wurtele
  • TAL effector-mediated DNA modification
    Patent number: 10400225
    Abstract: Materials and methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: September 3, 2019
    Assignees: Regents of the University of Minnesota, Iowa State University Research Foundation, Inc.
    Inventors: Daniel F. Voytas, Adam J. Bogdanove, Feng Zhang
  • Polymers and methods of making the same
    Patent number: 10392471
    Abstract: Various embodiments disclosed relate to polymers and methods of making the same. In various embodiments, the present invention provides a method of forming a polymer including subjecting a composition including a carboxylic acid having the structure (Rf—O)z1—Ra to conditions sufficient to form a polymer having the structure Reg—[O—Ra(O—Rb)z1-2—O—C(O)—R?(O—Rd)z2-1—C(O)]n—O—Ra(O—Rb)z1-2—O—Reg or a salt or ester thereof, wherein Ra, R? Rb, Rd, Rf, Reg, z1, z2, and n are as defined herein. In various embodiments, the polymer is a tackifier, a viscosifier, or a combination thereof.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: August 27, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Jason Shih-Hao Chen, Michael Dennis Zenner