Abstract: The invention provides non-crosslinked and crosslinked block copolymers comprising at least one block A comprising repeating units derived from monomers comprising one or more C1-C3 alkyl (meth)acrylamides and/or (meth)acrylates and at least one block B comprising repeating units derived from monomers comprising one or more C4-C40 alkyl (meth)acrylamides. The invention further provides compositions comprising the block copolymers and applications thereof in various industrial areas including personal care. The invention furthermore provides compositions comprising colloidal particles of the block copolymers. The variables x, y, R1, and R2 are described herein.

Abstract: This application provides reactive, flexible, water-resistant hydroxyethylpyrrolidone methacrylate/glycidyl methacrylate copolymers having the structure: wherein a and b are integers, the sum of which less than 100, covalently linked to active agents that are useful in a wide variety of compositions. The present application also discloses hydroxyethylpyrrolidonemethacrylate/glycidyl methacrylate copolymer convently linked to one or more surface active moiety having a structure: wherein a, b, and c are integers, the sum of which equals 100, and M is a surface-active moiety.

Abstract: The invention provides a process for removal of a thio-based end group from a polymer comprising repeating units derived from at least one monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety by subjecting the polymer to radiation in a reaction medium devoid of any chemical reagent. Exemplary process involves removal of thio-based end groups from polymers prepared by reversible addition-fragmentation chain transfer polymerization of at least one monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety by exposing the polymer to visible radiation in a reaction medium devoid of any chemical reagent.

Abstract: A substantially anhydrous thickener system in the form of a gel for use in oral care compositions comprising: carboxymethyl cellulose or its salts thereof, a chelating agent, and hydroxyethyl cellulose, in a solvent system, wherein the thickener system is heated to a temperature ranging from about 70° C. to about 120° C. to form the gel. A method of preparing the thickener system for use in oral care compositions comprises the steps of: a) charging a mixture of hydroxyethyl cellulose and carboxymethyl cellulose into a reaction container, b) dissolving the mixture of a) in a solvent system, c) charging a chelating agent into b), and d) heating the resultant of c) to a temperature of 70°-120° C. for at least about 10 minutes.

Abstract: Methods and computing apparatus for implementing a radiation dosimetry process. An example process may include exposing a first radiation sensitive film to a series of known doses of radiation, measuring a first set of radiation data with a measurement device, and determining a calibration curve. The calibration curve may be determined by selecting Raman spectral ranges based on the first set of radiation data, determining a plurality of band area ratios, and generating the calibration curve based on plotting the band areas and ratios compared to known dose. The radiation dosimetry process then exposes a second radiation sensitive film to an unknown dose of radiation, measures a second set of radiation data for the second radiation sensitive film with the measurement device, and determines a dose exposure level for the second radiation sensitive film by comparing the second set of radiation data with the calibration curve.

Abstract: The present invention provides biodegradable microcapsules, that can encapsulate and retain cargoes such as, lipophilic or hydrophobic core materials comprising fragrances, butters, essential or other oils; or oil solubilized ingredients process of making said biodegradable microcapsules and their applications in various industries. Present invention further provides biodegradable shell materials that show evidence of biodegradation or non-persistence in aquatic based and/or soil or compost based environments.

Abstract: Present invention is directed to an artificial intelligence-based method and a system, that uses both experimental results data and molecular simulation to predict properties of amorphous solid dispersions such as glass transition temperature, dissolution profile, and/or physical stability. The method and system of the present invention enable rational design of amorphous solid dispersions for poorly water-soluble drugs and significantly reduce the time and resource required for amorphous solid dispersions formulation development.

Abstract: The invention relates to a process for obtaining aqueous extracts of tea leaves (Camellia sinensis), in particular of leaves of fresh tea, pu'er tea, matcha tea or green tea. The invention also relates to tea extracts enriched with small RNAs, sugars, phenolic compounds, organic acids, theine and theanine, as well as to cosmetic compositions comprising such extracts and their cosmetic uses for the care of the skin, the scalp, and the appendages and more particularly for protecting the skin from external aggressions and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin and improving skin hydration.

Abstract: The invention provides a method for preparation of homopolymers and non-homopolymers comprising polymerizing in an aqueous medium a monomer comprising at least one acryloyl moiety and at least one functionalized or unfunctionalized lactam moiety, and optionally at least one hydrophilic or hydrophobic comonomer, in the presence of at least one chain transfer agent and at least one non-radiation initiator. Exemplary diblock polymers prepared by the method have the structure: where subscripts x, y, and z and variables R, R8, R9 and R10 are described herein.

Abstract: The invention relates to a process for obtaining an aqueous extract of lavender enriched with small RNAs of a maximum length of 150 nucleotides, with sugars, with phenolic compounds, with organic acids and devoid of DNA, obtained by the following process: the lavender aerial parts are brought into contact with water; phytic acid is added at a pH of between 10 and 11; the pH of the mixture obtained is then adjusted to a value of between 6 and 8, the mixture obtained is purified. The invention also relates to cosmetic compositions comprising such an extract and their cosmetic uses for protecting the skin from external aggression and oxidation, combating the signs of skin ageing, increasing photoprotection, lightening the skin, improving hydration, reinforcing the barrier function, soothing the skin or improving the biological mechanisms associated with skin repair during the night.

Abstract: The present invention relates to composition comprising a bioactive fractions (ingredients) derived from fruit juice of an Apple (Pyrus malus) produced by processing the fresh fruit of apple under conditions effective to yield a bioactive fraction that is substantially free of protein and patulin. The present invention also relates to compositions having antioxidant and free radical scavenging properties and suitable for topical applications, oral applications and functional drink applications.

Abstract: The present invention provides bioactive compositions comprising Ficus serum fraction derived from Ficus cell juice of fresh Ficus leaves and a process of preparing the Ficus serum fraction. The compositions have biological activity capable of reducing skin hyperpigmentation.

Abstract: Disclosed herein are methods of improving skin appearance associated with skin aging. The method comprises the step of applying an anti-aging bioactive composition to a skin surface having at least one sign of aging. The anti-aging bioactive composition is applied for a period of time sufficient to improve the appearance of the at least one sign of aging. In one embodiment, the anti-aging bioactive composition comprises an effective amount of a Nelumbo nucifera (Sacred Lotus) serum fraction. In another embodiment, the anti-aging bioactive composition comprises an effective amount of a Chamomilla recutita (German Chamomile) Flower serum fraction. In other embodiments, the anti-aging bioactive composition can further include a dermatologically acceptable carrier.

Abstract: An oral care antimicrobial composition comprises about 0.1 to about 99.9 wt. % of at least one compound having the structure of Also disclosed is a process for preparing the composition and methods of use thereof.

Abstract: This present disclosure provides a multi-ply radiation dosage indicator, which includes a first ply having two visible readable indicia thereon. The dual radiation sensitive zones are capable of changing opacity in response to exposure radiation. Each radiation sensitive zone can respond to an irradiation dose in tandem or independent of one another. Once the radiation sensitive zone exceeds the design exposure threshold, the visibility of the indicia is altered thereby providing an indication of irradiation exposure. The radiation sensitive zone may either be transparent or opaque and can change its opacity in response to exposure to radiation exceeding a predetermined threshold so as to change the visibility of the indicia.

Abstract: The present application provides hydrogel microcapsules, particularly, canonized hydrogel microcapsules having improved substantivity. This application further relates to the use of hydrogel microcapsules for delivering encapsulated actives in a wide range of industries and applications including: agrochemicals, pharmaceuticals, cosmetics industry, personal care products, laundering detergents, homecare & cleaning products, dish washing detergents, oral care, dental care, textiles, paper, mining, oil industry, water treatment, adhesives, coatings, plastics, sealants, construction, paints, inks and dyes onto different substrate surfaces such as skin, hair, textiles.

Abstract: The present application provides an antimicrobial composition comprising: (a) about 0.01 to about 99.9 wt. % of at least one compound having a structure of formula (I) or formula (II): wherein R1 is hydrogen, alkyl, alkoxy or hydroxyl; R2 is hydrogen, alkyl or alkoxy; and (b) about 0.1 to about 95% wt. % of one or more antimicrobial compounds not being compounds of formula (I) and formula (II). Also disclosed is a process for preparing the compositions and method of use thereof.

Abstract: The present disclosure relates to a suspending polymer composition comprising a blend of: (i) about 40 to about 80 wt. % of hydroxypropylmethylcellulose (HPMC); (ii) about 10 to about 30 wt. % of xanthan gum; and (iii) about 10 to about 30 wt. % of cetyl-hydroxy ethyl cellulose (cetyl-HEC) for use in personal care or home care compositions. The suspending polymer composition preferably is free of acrylates, methacrylates and derivatives thereof.

Abstract: The invention relates to a topical composition comprising an extract of Tiger lily (Lilium tigrinum) enriched in low molecular weight RNA. The invention also relates to a method of cosmetic care including the topical application a composition comprising an extract of Tiger lily (Lilium tigrinum) in a physiologically acceptable medium, in order to reduce skin signs of aging and photo-aging. The invention is also directed to a cosmetic method of treatment to improve cell viability, to improve cell protection against particulate matter and against DNA damages, and to reduce cellular senescence.

Abstract: The invention relates to the method for obtaining an extract of sandalwood (Santalum album) by extraction using a supercritical fluid and a co-solvent chosen from primary or secondary alcohols. The invention also relates to a crude extract of sandalwood comprising from 10 to 70% of volatile compounds and from 30 to 90% of semi- to non-volatile compounds.