Patents Assigned to J. Craig Venter Institute
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Patent number: 12011467Abstract: Aspects of the present invention relate to compositions of bacterial isolates with probiotic activity. Aspects of the present invention also relate to compositions and methods that may confer health benefits to subjects in need thereof. This may be accomplished by administering to the subject an effective amount of the microorganism isolates and may include also administering an effective amount of a prebiotic, stabilizer, antibacterial agent, antifungal agent, and/or media component. Probiotic compositions may also be in combination with a suitable delivery system, such as a food product or a beverage, a food or beverage compositions, a food or beverage supplement or adjuvant.Type: GrantFiled: May 16, 2022Date of Patent: June 18, 2024Assignee: J. Craig Venter Institute, Inc.Inventors: Craig Venter, Karen Nelson, Derrick E. Fouts, Weizhong Li, Aubrie O'Rourke, Manolito Torralba
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Patent number: 11964944Abstract: Disclosed herein are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.Type: GrantFiled: June 2, 2022Date of Patent: April 23, 2024Assignees: The University of Chicago, J. Craig Venter Institute, Inc., The University of Sheffield, Institute for Systems Biology, The University of Leeds, The University of Strathclyde, The Government of the United StatesInventors: Rima McLeod, Martin McPhillie, Colin W. G. Fishwick, Hernan Alejandro Lorenzi, Kai Wang, Taek-Kyun Kim, Yong Zhou, Leroy E. Hood, Ying Zhou, Kamal El Bissati, Mark Hickman, QiGui Li, Craig Roberts
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Patent number: 11351140Abstract: Provided herein are compositions comprising a resolvin mimetic. Such mimetics may comprise an anti-ERV1 antibody, such as a resolvimab, or biologically-active antibody fragment thereof. Also provided herein are methods for treating or preventing an inflammatory disorder in a subject in need thereof comprising the steps of administering a therapeutically effective amount of at least one resolvin mimetic.Type: GrantFiled: May 17, 2018Date of Patent: June 7, 2022Assignee: J. Craig Venter InstituteInventor: Marcelo Freire
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Patent number: 10988773Abstract: Described herein are engineered microalgae that exhibit enhanced lipid production during exponential growth. Such engineered microalgae are useful, for example, for the production of biofuels.Type: GrantFiled: January 16, 2018Date of Patent: April 27, 2021Assignee: J. Craig Venter InstituteInventors: Andrew Allen, Christopher L. Dupont
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Publication number: 20200163922Abstract: Provided herein are compositions comprising a resolvin mimetic. Such mimetics may comprise an anti-ERV1 antibody, such as a resolvimab, or biologically-active antibody fragment thereof. Also provided herein are methods for treating or preventing an inflammatory disorder in a subject in need thereof comprising the steps of administering a therapeutically effective amount of at least one resolvin mimetic.Type: ApplicationFiled: May 17, 2018Publication date: May 28, 2020Applicant: J. Craig Venter InstituteInventors: Marcelo FREIRE, Thomas E. van DYKE
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Patent number: 10428121Abstract: The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences. Data are given to show that the proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics. The proteins are also targets for antibiotics.Type: GrantFiled: November 7, 2017Date of Patent: October 1, 2019Assignees: Novartis AG, J. Craig Venter Institute, Inc.Inventors: John Telford, Vega Masignani, Maria Scarselli, Guido Grandi, Herve Tettelin, Claire Fraser
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Publication number: 20180298064Abstract: Disclosed herein are various open reading frames from a strain of E. coli responsible for neonatal meningitis (MNEC), and a subset of these that is of particular interest for preparing compositions for immunising against MNEC infections.Type: ApplicationFiled: June 26, 2018Publication date: October 18, 2018Applicants: GlaxoSmithKline Biologicals SA, J. Craig Venter Institute, Inc.Inventors: Vega MASIGNANI, Danilo Gomes MORIEL, Francesco BERLANDA SCORZA, Nathalie NORAIS, Maria Rita FONTANA, Mariagrazia PIZZA, Laura SERINO, Hervé TETTELIN
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Patent number: 9868959Abstract: Described herein are engineered microalgae that exhibit enhanced lipid production during exponential growth. Such engineered microalgae are useful, for example, for the production of biofuels.Type: GrantFiled: December 13, 2011Date of Patent: January 16, 2018Assignee: J. Craig Venter InstituteInventors: Andrew Allen, Christopher Lee Dupont
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Patent number: 9840538Abstract: The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences. Data are given to show that the proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics. The proteins are also targets for antibiotics.Type: GrantFiled: June 26, 2015Date of Patent: December 12, 2017Assignees: Novartis AG, J. Craig Venter Institute, Inc.Inventors: John Telford, Vega Masignani, Maria Scarselli, Guido Grandi, Herve Tettelin, Claire Fraser
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Patent number: 9795642Abstract: Bacteriophages are provided that infect strains of Enterococcus faecalis, an opportunistic bacterial pathogen that causes human disease. Also provided are methods of treating Enterococcus faecalis by therapeutic administration of such bacteriophages.Type: GrantFiled: March 25, 2014Date of Patent: October 24, 2017Assignees: TEMPLE UNIVERSITY—Of The Commonwealth System of Higher Education, J. Craig Venter Institute, Inc.Inventors: Roy H. Stevens, Hongming Zhang, Derrick E. Fouts, Jessica DePew
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Patent number: 9738693Abstract: The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences. Data are given to show that the proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics. The proteins are also targets for antibiotics.Type: GrantFiled: May 26, 2016Date of Patent: August 22, 2017Assignees: Novartis AG, J. Craig Venter Institute, Inc.Inventors: John Telford, Vega Masignani, Maria Scarselli, Guido Grandi, Herve Tettelin, Claire Fraser
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Patent number: 9505636Abstract: A modular device that is optimized for preliminary water treatment and energy generation and methods for operating the same are described.Type: GrantFiled: January 14, 2011Date of Patent: November 29, 2016Assignee: J. Craig Venter InstituteInventor: Orianna Bretschger
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Publication number: 20160244489Abstract: Disclosed herein are various open reading frames from a strain of E. coli responsible for neonatal meningitis (MNEC), and a subset of these that is of particular interest for preparing compositions for immunising against MNEC infections.Type: ApplicationFiled: May 9, 2016Publication date: August 25, 2016Applicants: GlaxoSmithKline Biologicals SA, J. Craig Venter Institute, Inc.Inventors: Vega MASIGNANI, Danilo Gomes MORIEL, Francesco BERLANDA SCORZA, Nathalie NORAIS, Maria Rita FONTANA, Mariagrazia PIZZA, Laura SERINO, Herve TETTELIN
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Publication number: 20140243220Abstract: Described herein are methods for analyzing complex host-microbial mixtures. The disclosed methods may be used to diagnosis or prognose in a subject an inflammatory disease, which is caused by or contributed to by microbes.Type: ApplicationFiled: February 25, 2014Publication date: August 28, 2014Applicant: J. Craig Venter InstituteInventor: Rembert Pieper
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Patent number: 8758764Abstract: Disclosed herein are various open reading frames from a strain of E. coli responsible for neonatal meningitis (MNEC), and a subset of these that is of particular interest for preparing compositions for immunising against MNEC infections.Type: GrantFiled: February 17, 2006Date of Patent: June 24, 2014Assignees: Novartis Vaccines and Diagnostics Srl, J. Craig Venter InstituteInventors: Vega Masignani, Danilo Gomes Moriel, Francesco Berlanda Scorza, Nathalie Norais, Maria Rita Fontana, Mariagrazia Pizza, Laura Serino, Herve Tettelin
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Publication number: 20140141286Abstract: Featured herein are oxygen reduction electrodes configured in an electrochemical system, such as a microbial fuel cell, comprising a cathode configured as a pleated sheet and an anode comprised of a conductive material.Type: ApplicationFiled: August 16, 2013Publication date: May 22, 2014Applicant: J. Craig Venter InstituteInventors: Orianna Bretschger, Greg Wanger
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Patent number: 8524251Abstract: The invention provides proteins from Neisseria meningitidis, including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for vaccines and/or diagnostics.Type: GrantFiled: January 26, 2012Date of Patent: September 3, 2013Assignees: J. Craig Venter Institute, Inc., Novartis AGInventors: Claire Fraser, Cesira Galeotti, Guido Grandi, Erin Hickey, Vega Masignani, Marirosa Mora, Jeremy Petersen, Mariagrazia Pizza, Rino Rappuoli, Giulio Ratti, Vincenzo Scarlato, Maria Scarselli, Herve Tettelin, J. Craig Venter
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Patent number: 8491918Abstract: Various specific meningococcal proteins are disclosed. The invention provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by meningococcus, such as bacterial meningitis.Type: GrantFiled: October 13, 2011Date of Patent: July 23, 2013Assignees: J. Craig Venter Institute, Inc., Novartis AGInventors: Rino Rappuoli, Claire Fraser, Mariagrazia Pizza, Maria Scarselli, Davide Serruto, Hervé Tettelin
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Publication number: 20130178377Abstract: Described herein are highly accurate metaproteomic based methods for diagnosing urogenital and kidney infections, which are easy to perform and that also provide information regarding the extent of the infection, the causative agent(s) and the nature of the host response.Type: ApplicationFiled: December 27, 2012Publication date: July 11, 2013Applicant: J. Craig Venter InstituteInventor: J. Craig Venter Institute
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Publication number: 20130129740Abstract: The invention provides proteins from group B streptococcus (Streptococcus agalactiae) and group A streptococcus (Streptococcus pyogenes), including amino acid sequences and the corresponding nucleotide sequences. Data are given to show that the proteins are useful antigens for vaccines, immunogenic compositions, and/or diagnostics. The proteins are also targets for antibiotics.Type: ApplicationFiled: August 30, 2012Publication date: May 23, 2013Applicants: J. Craig Venter Institute, Novartis Vaccines and Diagnostics, Inc.Inventors: John Telford, Vega Masignani, Maria Scarselli, Guido Grandi, Hervé Tettelin, Claire Fraser