Abstract: The present invention relates to a composition comprising an NF?B-inhibitor and a tropoelastin promoter, and methods of treating signs of skin aging using said compositions.

Abstract: A topical composition containing galvanic particulates consisting of a first conductive material that is zinc and a second conductive material that is copper is provided.

Abstract: Aqueous compositions including a discontinuous oil phase containing an ultraviolet radiation-absorbing polymer stabilized in a continuous aqueous phase, an oil-gelling polymer, and which are substantially free of non-polymeric ultraviolet radiation-absorbers.

Abstract: A composition including a retinoid, an NF?B-inhibitor, and a cosmetically-acceptable topical carrier is provided. Methods of treating the skin are also provided.

Abstract: The present invention relates to a composition comprising an NF?B-inhibitor and a non-retinoid collagen promoter.

Abstract: Provided are compositions comprising one or more compounds having a structure comprising a node structure with from four to twelve carbon atoms, one or more (poly)glyceryl groups, and one or more hydrophobic moieties, wherein each of the one or more (poly)glyceryl groups is linked to the node structure by a first primary linking group, the one or more hydrophobic moieties are each independently linked either to the node structure by a primary linking group or to one of the (poly)glyceryl groups by a secondary linking group, and wherein the polyglyceryl thickener has an average degree of glyceryl polymerization of from greater than 3 to less than about 11 and an average number of hydrophobic groups per primary linking group of about 0.35 or greater. Also provided are polyglyceryl compounds, compositions comprising water, a surfactant, and a polyglyceryl thickener, as well as, methods of making polyglyceryl compounds and compositions of the present invention.

Abstract: We have disclosed dicephalic amphiphiles having peptide sequences as the head groups. We have also disclosed self-assembly hydrogels prepared from the dicephalic peptide amphiphiles. These hydrogels are useful for the encapsulation and delivery of bioactives to a patient.

Abstract: Enterically coated particles and chewable tablets made therefrom are disclosed. The enterically coated particles are comprised of a core containing an active ingredient, a first coating layer comprised of polymeric composition having a Tg less than about 40° C. that substantially covers the core; and a second coating layer, which substantially covers the first coating layer, comprised of a high temperature film forming polymer. The particles may be produced into a tablet form, such as a chewable tablet form, that provides for the immediate release of the active ingredient.

Abstract: Described are skin-care compositions containing non denatured soy products and optionally other anti-cancer or anti-aging agents. The compositions can be applied topically to reduce the risk of UV-induced cutaneous tumors in skin cells that have not yet been damaged by ultraviolet radiation.

Abstract: A skin care element holder is designed for use with a handheld body having a receptacle. The skin care element holder includes a substantially circular plate having a diameter between about 20 and about 60 mm. The substantially circular plate has a first surface arranged and configured for coupling to the skin care element; a second surface, opposite the first surface; and an outer peripheral edge. The second surface of the substantially circular plate has at least one spacer leg; a plurality of engagement arms; and at least one key. Each of the at least one spacer leg, engagement arms and key extend from the second surface in a direction away from the first surface. The at least one spacer leg supports the plate in the receptacle. At least one of said engagement arms includes a snap-fit projection for engagement with a recess in the receptacle. The key is arranged and configured to fit into a notch in the receptacle. Handheld skin care systems incorporating the skin care holder are also described.

Abstract: Substantially anhydrous compositions including at least 10% by weight of a C2 or C3 mono-alcohol, a solid, organic UV-filter dissolved therein; and an oil portion including one or more oils, the oil portion having an interfacial tension with water of greater than 9 and less than 45, where the composition has a volume fraction of oil relative to oil plus C2 or C3 mono-alcohol that is about 0.47 or greater, and is substantially free of a mixture of a low-volatility, C2-C8 liquid silicone and a branched fatty acid ester of a polyprotic carboxylic acid in a ratio of from about 3:1 to 4.

Abstract: Presented are methods of using topical analgesic compositions for rapid relief of muscular aches and pain where the analgesic composition has been stored at a temperature of less than 10° Centigrade prior to use.

Abstract: The invention relates to methods and compositions for treating skin aging, said compositions comprising at least one tropoelastin promoter and at least one tropoelastin crosslinker.

Abstract: Provided are compositions comprising one or more compounds having a structure comprising a node structure with from four to twelve carbon atoms, one or more (poly)glyceryl groups, and one or more hydrophobic moieties, wherein each of the one or more (poly)glyceryl groups is linked to the node structure by a first primary linking group, the one or more hydrophobic moieties are each independently linked either to the node structure by a primary linking group or to one of the (poly)glyceryl groups by a secondary linking group, and wherein the polyglyceryl thickener has an average degree of glyceryl polymerization of from greater than 3 to less than about 11 and an average number of hydrophobic groups per primary linking group of about 0.35 or greater. Also provided are polyglyceryl compounds, compositions comprising water, a surfactant, and a polyglyceryl thickener, as well as, methods of making polyglyceryl compounds and compositions of the present invention.

Abstract: The present invention features a method of treating at least one sign of aging on the skin selected from the group consisting of enhancing the elasticity of said skin, enhancing the firmness of said skin, and reducing the appearance of wrinkles or cellulite on the skin, by administering to skin in need of such treatment a composition comprising at least one compound of the formula I or formula II: wherein R1, R2, R3, R4, and R5 independently, are selected from the group consisting of hydrogen, C1-C6 alkyl, C1-C6 hydroxyalkyl, or a cosmetically acceptable salt thereof.

Abstract: The methods and compositions of this invention relate to compositions having low irritation characteristics in combination with one or more additional characteristics, for example, relatively high clarity, relatively high foaming, and/or combinations thereof, as well as methods of making and using such compositions. These compositions have low pH values and are useful in cleansing the skin.

Abstract: The methods and compositions of this invention relate to compositions containing polyglyceryl esters of fatty acids, low molecular weight hydrophobically-modified polymers and anionic and/or amphoteric surfactants having low irritation characteristics in combination with one or more additional characteristics, for example, relatively high clarity, relatively high foaming, and/or combinations thereof, as well as methods of making and using such compositions. These compositions have low pH values and are useful in cleansing the skin.

Abstract: The methods and compositions of this invention relate to compositions having low irritation characteristics in combination with one or more additional characteristics, for example, relatively high clarity, relatively high foaming, and/or combinations thereof, as well as methods of making and using such compositions. These compositions have low pH values and are useful in cleansing the skin.