Abstract: A packaging for an ophthalmic lens containing a pharmaceutical agent.

Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Abstract: A method for estimating and tracking refractive error progression of an individual includes estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual's age by comparison to a reference population; estimating an expected SPHEQ trajectory over a future predetermined period of time; comparing the expected SPHEQ trajectory with the reference population; and comparing the expected SPHEQ trajectory with an expected SPHEQ trajectory using an ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some embodiments, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a laminate stack of biocompatible material. In some embodiments, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: A molded contact lens comprising a stiffer optic zone relative to the peripheral zone of the contact lens provides an optical element for correcting astigmatism without the need for or substantially minimizing the need for the correction of rotational misalignment. The higher elastic modulus optic zone vaults over the cornea thereby allowing a tear lens to form. The tear lens follows or assumes the shape of the back surface of the contact lens. The combination of the tear lens and the optical zone provide an optical element for correction of refractive error.

Abstract: A method of measuring the thickness of an ophthalmic lens includes providing an ophthalmic lens having a light absorptive component, and passing light having a wavelength through the ophthalmic lens whereupon the light absorptive component absorbs some of the light as the light passes through the ophthalmic lens. After the light has passed through the ophthalmic lens, the light is used to generate a digital image for the ophthalmic lens that has pixel intensity data that corresponds to the shape of the ophthalmic lens. Information about the light prior to passing through the ophthalmic lens, the light absorptive component of the ophthalmic lens, and the pixel intensity data is used to calculate a thickness profile for the ophthalmic lens.

Abstract: Device and methods for sealing and encapsulation for biocompatible energization elements are described. In some examples, the device and methods for sealing and encapsulation for biocompatible energization elements involve heat welding, laser welding, or both where a laminar structure is enclosed by a polymer film capable of sealing. In some examples, a field of use for the apparatus and methods may include any biocompatible device or product that requires energization elements.

Abstract: The present invention relates to ophthalmic compositions and methods for the treatment of dry eye and other inflammatory ocular conditions. In particular, the present invention relates to a composition comprising an esterified anti-inflammatory lipid mediator, which is an ester of an anti-inflammatory lipid mediator that is a reaction product of the anti-inflammatory lipid mediator and a polyol wherein the majority of the anti-inflammatory lipid mediator is present in an ester form. In this way, the compositions are substantially free of an acid form of the anti-inflammatory lipid mediators. This composition can be topically delivered to the ocular surface via a preparation, solution, gel, ointment, and/or strip and/or a contact lens.

Abstract: A flexible micro-battery construction which can be contorted in three dimensions while maintaining operation and providing biocompatibility and useful power necessary for small medical and other devices is provided.

Abstract: This invention discloses apparatus for generating an ophthalmic lens with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic lens is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture.

Abstract: Methods and apparatus to form biocompatible energization elements are described. In some embodiments, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a laminate stack of biocompatible material. In some embodiments, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Abstract: A powered ophthalmic lens having an electronic system is described herein configured to communicate with an external device using an ultrasound module for creating a sound pressure wave(s) to be transmitted through a medium, e.g. air, to an external device. The ophthalmic lens includes at least one ultrasound module having at least one transducer such as a pair of transmit and receive transducers, a transceiver transducer or a plurality of transducers. The ultrasound module includes additional components for the creation and reception of the sound pressure wave(s). In an alternative embodiment, there is one ultrasound module with a multiplexer connected to a plurality of transducers. In at least one embodiment, the sound pressure wave(s) encodes a message from the external device to the contact lens. In at least one alternative embodiment, the sound pressure wave(s) encodes a message from the contact lens to the external device.

Abstract: Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxyphenyl naphthotriazole structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxyphenyl naphthotriazole structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.

Abstract: The present invention relates generally to an arcuate liquid meniscus lens with a meniscus wall. Some specific embodiments include a liquid meniscus lens with a meniscus wall essentially in the shape of multiple segments of a frustum of a cone. Embodiments may also include a lens of suitable size and shape for inclusion in a contact lens.

Abstract: Provided are compositions comprising a block copolymer of the following formula: [A]-B-[Q], wherein [A] is a polymer that has an affinity for a substrate; B is a linking group comprising an optionally-substituted, polyvalent linking group having a molecular weight of no more than 1000 g/mole; and [Q] comprises a semi-crosslinked, ungelled polymer derived from copolymerization of an ethylenically unsaturated monomer with a poly-functional ethylenically unsaturated monomer. Such block copolymers are cross-linked via the [Q] segment, but not macroscopically gelled. The [Q] segment is hydrophilic and has a degree of polymerization in the range of about 10 to about 10,000. The [A] segment is located on at least one terminal end of said block copolymer, comprises between about 1 and about 200 repeating units. The block copolymer is associated, via the linear substrate associative segment with a surface comprising at least one hydrophobic site, such as a silicone hydrogel.

Abstract: Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.

Abstract: The present disclosure relates to sensor systems for electronic ophthalmic devices. In certain embodiments, the sensor systems may comprise a sensor such as an adjustable resistor configured in series with an eye of a user of the electronic ophthalmic device. The sensor systems may comprise a gain stage configured to amplify a signal indicative of a difference between a voltage drop across the eye and the adjustable resistor. The sensor systems may comprise an integrator configured to integrate the amplified signal. A resistance value of the adjustable resistor is configured to cancel a DC component of a resistance of the eye when an electrical current is caused to flow through the eye and the adjustable resistor. As such, the configured resistance value of the adjustable resistor is indicative of an impedance of the eye.

Abstract: The present disclosure relates to sensor systems for electronic ophthalmic devices. In certain embodiments, the sensor systems may comprise a vibration sensor disposed adjacent an eye of a user, the vibration sensor configured to detect a vibration caused at least in part by ciliary muscle movement, the vibration sensor further configured to provide an output and a processor configured to receive the output and to determine a characteristic of the output indicative of the ciliary muscle movement.

Abstract: A system and method for assessing optical corrective needs of a patient. The system includes a computer system including a processor adapted to run at least a refractive software application thereon, an input device in communication with said processor and adapted to receive input from a user, and a displace device in communication with said processor and adapted to display information, and refractive eyewear including electrically adjustable left and right lenses selectively controllable to adjust at least a sphere power of the respective lenses and in communication with the processor. The refractive software application receives input from the input device and the eyewear controller, and selectively adjusts the sphere power of the left and right lenses, controls information displayed on said display device, and stores information regarding the sphere power of the respective left and right lenses.

Abstract: A contact lens having a lens edge defining an outer periphery of the contact lens, an optic zone positioned within the lens edge designed to provide corrective vision for a patient, a Lens Center having a vertical axis and a horizontal axis passing therethrough, and first and second fiducial indicators present at first and second different locations around the lens edge. The first and second fiducial indicators each include at least one recess into or at least one projection extending outwardly from the lens edge and are different from one another.