Abstract: An ophthalmic lens comprises a main body having a toric surface and a spherical surface opposite the toric surface, the main body comprising an eyelid stabilization design structure having a thickness of less than 200 ?m, wherein the spherical surface is configured to exhibit a lens spherical power, wherein the toric surface is configured to exhibit a lens cylindrical power that does not fully correct ocular cylindrical power due to astigmatism; and wherein the lens spherical power is configured such that the minimum circle of the ophthalmic lens is on or adjacent the retina of the eye of the wearer at a target angle of alignment.

Abstract: The present invention relates to ophthalmic compositions and methods for the treatment of dry eye and other inflammatory ocular conditions. In particular, the present invention relates to a composition comprising an esterified anti-inflammatory lipid mediator, which is an ester of an anti-inflammatory lipid mediator that is a reaction product of the anti-inflammatory lipid mediator and a monohydric alcohol or an amide wherein the majority of the anti-inflammatory lipid mediator is present in an ester form. In this way, the compositions are substantially free of an acid form of the anti-inflammatory lipid mediators. This composition can be topically delivered to the ocular surface via a preparation, solution, gel, ointment, and/or strip and/or a contact lens.

Abstract: A photochromic ophthalmic lens may comprise a main body comprising an optical zone and a peripheral zone disposed adjacent the optical zone, wherein one or more of the optical zone and the peripheral zone comprises a photochromic dye, wherein the ophthalmic lens has a thickness profile that is configured based on cosmetic appearance associated with a target level of transmission (% T), and wherein at least a portion of the thickness profile is the same across two or more stock keeping units (SKU), each of the two or more SKU having a different target prescription.

Abstract: The invention provides an improved rotationally stabilized contact lens design and method of designing such a lens which minimizes stabilization time of the lens while maximizing the lens on-eye comfort. The lens and the method of designing the lens further improves upon an earlier method which utilizes and combines non-circularity and thickness differential aspects which results in equivalent or minimized stabilization time, ease of insertion and manufacturability as well as maximum comfort that is improved over that of what either aspect can achieve independently. This further improvement of stiffness profile is achieved by optimizing and selectively addressing thickness differential both diametrically and circumferentially in a non-round lens design.

Abstract: A contact lens applicator film (45) for picking up a contact lens (11) and applying the contact lens to an eye comprising: a sterilised film (45) wherein at least a portion of at least one side of the film comprises an adhesive coating that is arranged for adhering to the surface of a finger such that, in use, when applying the contact lens to the eye a user can pick up the contact lens applicator film with the finger and subsequently pick up the contact lens using the finger protected by the contact lens applicator film.

Abstract: The present invention relates to ionic silicone hydrogel polymers displaying improved lysozyme uptake, low contact angle and reduced water soluble polymeric ammonium salt uptake.

Abstract: Contact lenses incorporating an array of non-coaxial lenslets with add power that create non-coaxial myopic defocus within the optic zone of the lens may be utilized to prevent and/or slow myopia progression. The positive, non-coaxial lenslets cover about twenty to eighty percent of the central pupil area to deliver positive foci of light in front of the retina to slow the rate of myopia progression.

Abstract: This invention provides for a method and an EMDU used to dispense precise quantities of liquids with an image sensor being capable of providing feedback to the user as to both, when an eye is properly aligned with the EMDU, and to detect and track the quantity of the dose administered on to the eye.

Abstract: Described are polymerizable high energy light absorbing compounds of formula I: Wherein Y, Pg, R1, R2, R3, R4, R5, and R6 are as described herein. The compounds absorb various wavelengths of ultraviolet and/or high energy visible light and are suitable for incorporation in various products, such as biomedical devices and ophthalmic devices.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator; (c) contacting the crosslinked substrate network with a grafting composition containing one or more ethylenically unsaturated compounds, wherein the contacting is conducted under conditions such that the grafting composition penetrates into the crosslinked substrate network; and (d) activating the covalently bound activatable free radical initiator at one or more selective regions of the crossli

Abstract: Provided are articles such as medical devices which comprise at least one water soluble, crosslinked copolymer. The primary polymer chains of the copolymer are hydrophilic and independently have a degree of polymerization in the range of about 10 to about 10,000. The water soluble, crosslinked copolymers of the present invention are free from terminal substrate associating segments. The copolymers may be incorporated into a formulation from which the article is made or may be contacted with the article post-formation.

Abstract: An apparatus and method for forming a contact lens includes submerging a convex optical quality surface of a forming optic in a reservoir containing Lens Reactive Mixture, projecting a first Actinic Radiation with a first wavelength through pre-selected regions of the forming optic that correspond to increased thickness in the lens to be formed for selectively polymerize the Lens Reactive Mixture on a Voxel by Voxel basis; projecting a second Actinic Radiation with a different wavelength through the entire forming optic to selectively polymerize the Lens Reactive Mixture on a Voxel by Voxel basis, removing the forming optic and polymerized Lens Reactive Mixture from the reservoir and applying a Fixing Radiation to form the contact lens.

Abstract: The present invention is directed to a system that may be incorporated into currently available electronic devices such as laptops, cell-phones and tablets, that help the user to maintain a viewing distance that is safe for the eyes. In order to avoid near-point stress on the eyes which may lead to the onset of myopia and/or accelerate the progression of myopia, especially in children or young adults, the system of the present invention monitors viewing distance and automatically distorts the image and/or text display into a format that is unreadable, for example, through blurring or pixilation, when the device is too close to the viewer. Alternatively, the system may automatically turn off the display when the device is too close and turn the display on when the device is at the proper viewing distance.

Abstract: Ophthalmic lenses are described herein. An example ophthalmic lens may comprise a first surface. The example ophthalmic lens may comprise a second surface disposed opposite the first surface. The second surface may be configured to abut at least a portion of an eye of a wearer. The example ophthalmic lens may comprise a lens stabilization zone disposed adjacent the first surface. At least a contour of the lens stabilization zone may be configured to minimize a recovery time for the ophthalmic lens to orient to a resting position from a misaligned position.

Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator, (c) combining the crosslinked substrate network with a second reactive composition containing one or more ethylenically unsaturated compounds; and (d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the second reactive composition polymerizes therein with the crosslinked substrate network to form a grafted polymeric network and a

Abstract: Methods and systems for adaptive configuration of ophthalmic devices are disclosed. An example method may comprise receiving, by a first sensor system disposed on or in a first ophthalmic device, sensor data representing movement of an eye of a user, wherein the first ophthalmic device is disposed within or upon an eye of the user; causing, based on the sensor data, storage of a history of movement of the eye; determining, based on the history of movement, a dwell characteristic indicating a distance at which the eye is fixated when an event occurs; and causing output of a signal indicative of performing an action in response to determining the dwell characteristic.

Abstract: Provided are ink compositions for making cosmetic contact lenses, as well as cosmetic contact lenses and methods for their preparation and use. The ink composition comprises: (a) a colorant; (b) a hydrophilic polymer; and (c) a binder polymer comprising a triblock polymer of formula: [A]-[B]-[C], wherein [A], [B] and [C] are as described herein.

Abstract: Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxyphenyl naphthotriazole structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxyphenyl naphthotriazole structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.

Abstract: Provided are ophthalmic devices comprised of a reaction product of a composition comprising: (i) a crosslinked substrate network containing covalently bound activatable free radical initiators; and (ii) a grafting composition containing one or more ethylenically unsaturated compounds. Also provided are processes for making ophthalmic devices.

Abstract: A biomedical device including an energy source, an electro-active device operatively connected to the energy source, circuitry configured to control operation of the electro-active device, at least one barrier layer including at least one inorganic material surrounding the energy source, electro-active device and circuitry, and at least one molded layer surrounding the at least one barrier layer. A method for encapsulating electronic components of an electro-active biomedical device in a protective envelope containing a barrier layer including at least one inorganic compound, and a molded polymer overcoat.