Abstract: To provide a solid-phase carrier that has extremely low nonspecific adsorption of biological substances such as proteins, peptides, nucleic acids and cells, and is capable of maintaining the activity of bound ligands at a high level; and a method for capturing a target substance using the solid-phase carrier.

Abstract: Provided is a lens solution which has excellent lipid detergency, exhibits high hydrophilization performance, and exhibits an excellent lipid adhesion preventive effect and an excellent lubricity-imparting effect when the solution is used to coat a lens. Disclosed is a lens solution containing a polymer having 2.5% to 95% by mass of the following repeating unit (A) and 2.5% to 95% by mass of the following repeating unit (B): (A) a hydrophilic repeating unit; and (B) a repeating unit having a polyoxyalkylene group in a side chain and having the end of the side chain formed from an alkyl group having 5 to 30 carbon atoms, an alkanoyl group having 5 to 30 carbon atoms, or an aryl group.

Abstract: There are provided a solid-phase carrier and a carrier for affinity refining that exhibit high dynamic binding capacity when a ligand is immobilized, have excellent antifouling properties, and are unlikely to have non-specific adsorption of impurities. The solid-phase carrier has a functional group capable of fixing a ligand and is characterized by having a group having a sulfinyl group, a sulfide group, an oxy group or an imino group, and a hydroxyl group, a thiol group, an amino group, a carboxy group, a sulfate group, a phosphate group or an alkanoyl group.

Abstract: The present invention relates to a method for assaying soluble GPC3 protein in a test sample, comprising using two different antibodies binding to different epitopes present in the N-terminal region of GPC3 protein.

Abstract: To provide a method for separating a vesicle having a lipid bilayer membrane, which has excellent efficiency of removing impurities and is unsuch asly to cause disruption of the vesicle having a lipid bilayer membrane. A method for separating the vesicle having the lipid bilayer membrane including: a complex forming step for forming a complex of the vesicle and the solid phase carrier by bringing a biological sample including a vesicle having a lipid bilayer membrane into contact with a solid phase carrier to which a ligand for recognizing a surface antigen present on a surface of the vesicle and is bound, a washing step for washing the complex, wherein at least any of the complex forming step and the washing step is performed in the presence of a nonionic surfactant.

Abstract: A surface treatment method for treating a surface formed of an inorganic material by using a polymer is provided. The polymer contains a repeating unit (A) having a cationic group with a particular structure in a side chain thereof and a repeating unit (B) having a group of a particular structure in a side chain thereof. Also provided are a tool and a device having a modified surface, and a method for producing the tool and the device.

Abstract: A solid-phase support, formed by binding a chain polymer at least to the surface, wherein the chain polymer is a block polymer comprising a first block constituted from repetitions of a hydrophilic structural unit and a second block constituted from repetitions of a structural unit having a reactive functional group, a content ratio of the number of moles “a” of the reactive functional group contained in the chain polymer and the number of moles “b” of the whole structural unit contained in the chain polymer, (a/b), is from 0.03 to 0.25, and a density of the chain polymer occupying the surface of the solid-phase support is 0.1 polymers/nm2 or more.

Abstract: A magnetic bead, formed by binding a chain polymer at least to the surface, in which the chain polymer is a chain polymer which has a hydrophilic repeating unit, and has a group comprising a reactive functional group at the end of the side, to which the magnetic bead does not bind, through an imino group or an N-substituted imino group, and a density of the chain polymer occupying the surface of the magnetic bead is 0.1 polymers/nm2 or more.