Patents Assigned to K.K. Ueno Seiyaku Oyo Kenkyujo
  • Patent number: 5107014
    Abstract: The present invention relates to a new prostagrandine I analogous compounds represented by the following formula (I) and (II). ##STR1## wherein R.sub.1 is a hydrogen atom or alkyl group, at least one of R.sub.2 and/or R.sub.2 ' are a halogen atom, an alkyl group, a group containing an aromatic group, a hydroxyl group or an alkoxy group providing that the R.sub.2 and R.sub.2 ' are not simultaneously hydrogen atoms or salt thereof, which compound is expected as hypotensives.
    Type: Grant
    Filed: May 10, 1990
    Date of Patent: April 21, 1992
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuzo Ueno, Ryuji Ueno, Tomio Oda
  • Patent number: 5106869
    Abstract: The present invention provides new compounds, 13,14-dihydro-15-keto-PGFs, and vassopressors containing them, which raise blood pressure without substantial ephemeral depression of blood pressure, trachea or enteron contraction effect inherent in usual PGFs.
    Type: Grant
    Filed: September 7, 1990
    Date of Patent: April 21, 1992
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuzo Ueno, Ryuji Ueno, Tomio Oda
  • Patent number: 5100879
    Abstract: A method of disinfection for retroviruses which comprises contacting inanimate object in need of such treatment with a natural or synthetic oligo- or polysaccharide having at least one S-oxoacid group attached to the saccharic carbon atom through a linking group of low molecular weight.
    Type: Grant
    Filed: August 24, 1989
    Date of Patent: March 31, 1992
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuzo Ueno, Ryuji Ueno, Sachiko Kuno, Akihiko Tabata
  • Patent number: 5096927
    Abstract: A method for treatment of a hepatobiliary disease which comprises administering, to a subject in need of such treatment, a 15-ketoprostaglandin compound in an amount effective in treatment of the hepatobiliary disease.
    Type: Grant
    Filed: October 19, 1990
    Date of Patent: March 17, 1992
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuji Ueno, Hiroyoshi Osama
  • Patent number: 5075334
    Abstract: Amethod for inducing decrease in potassium ion concentration in the blood which comprises administering, to a subject having an increased potassium ion concentration in the blood, a prostanoic acid derivative in an amount effective in inducing decrease in potassium ion concentration in the blood wherein said concentration is increased or for improving extracorporeal excretion of potassium ion in the blood which comprises administering, to a subject having an increased potassium ion concentration in the blood, a prostanoic acid derivative in an amount effective in improving extracorporeal excretion of potassium ion concentration is increased.
    Type: Grant
    Filed: July 26, 1990
    Date of Patent: December 24, 1991
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuji Ueno, Hiroyoshi Osama
  • Patent number: 5073569
    Abstract: The present invention provides novel prostaglandins D, that is, 13,14-dihydro-15-keto-PGDs, which have an excellent sedative and sleep-inducing activity, and so they are useful for tranquilizer and/or soporifics.
    Type: Grant
    Filed: September 6, 1989
    Date of Patent: December 17, 1991
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuzo Ueno, Ryuji Ueno, Ichie Kato, Tomio Oda
  • Patent number: 5071838
    Abstract: A method for treatment of shock which comprises administering, to a subject in need of such treatment, a cyclodextrin or a derivative thereof in an amount effective in such treatment.
    Type: Grant
    Filed: April 3, 1991
    Date of Patent: December 10, 1991
    Assignee: K. K. Ueno Seiyaku Oyo Kenkyujo
    Inventor: Ryuji Ueno
  • Patent number: 5068467
    Abstract: The present invention provides an improved method of producing solid sorbitol which hardly cakes even in long storage, in which seed crystals are dispersed in melted sorbitol at a temperature that the melted sorbitol does not solidify but the seed crystals do not melt, and cooled to about 50.degree. to 85.degree. C., kept at said temperature for a given period and then cooled again.
    Type: Grant
    Filed: July 12, 1990
    Date of Patent: November 26, 1991
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Yuji Kunimi, Akihiko Tabata, Yatsuka Fujita
  • Patent number: 5001154
    Abstract: This invention provides a fervescence composition containing 15-keto-PHEs separated from any substantial activity such as decrease of blood pressure.
    Type: Grant
    Filed: November 22, 1989
    Date of Patent: March 19, 1991
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuzo Ueno, Ryuji Ueno, Tomio Oda
  • Patent number: 5001153
    Abstract: The present invention relates to ocular hypotensive agents which contains 13,14-dihydro-15-keto-prostagrandins, which shows no transient ocular hypertensive response that PGs usually show.
    Type: Grant
    Filed: September 19, 1988
    Date of Patent: March 19, 1991
    Assignee: K.K. Ueno Seiyaku Oyo Kenkyujo
    Inventors: Ryuzo Ueno, Ryuji Ueno, Tomio Oda