Patents Assigned to Kanagawa Academy of Science and Technology
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Publication number: 20170229179Abstract: A memory circuit includes: cells arranged in rows and columns so that the rows are grouped to form banks each including one or more rows, each cell including: a bistable circuit storing data; and a non-volatile element storing data stored in the bistable circuit in a non-volatile manner and restoring data stored in a non-volatile manner to the bistable circuit; and a controller that performs a store operation on each row in turn; sets a voltage supplied, as a power-supply voltage, to cells in a first bank, which includes a row on which the store operation is performed, of the banks to a first voltage; and sets a voltage supplied, as a power-supply voltage, to cells in a bank of the banks other than the first bank to a second voltage that is less than the first voltage but at which data in the bistable circuit is retained.Type: ApplicationFiled: August 6, 2015Publication date: August 10, 2017Applicants: JAPAN SCIENCE AND TECHNOLOGY AGENCY, KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGYInventors: Satoshi Sugahara, Yusuke Shuto, Shuichiro Yamamoto
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Patent number: 9642934Abstract: The present invention aims to provide a bone regeneration material kit, a paste-like bone regeneration material, a bone regeneration material, and a bone bonding material, which contain particles including a bioabsorbable polymer; and can fill a bone defect or damage and secure the mechanical strength of the bone in the short term and can promote regeneration of the patient's own bone in the long term. In addition, they can exhibit anti-washout properties after filling even when they are in contact with water such as blood or biological fluids. The present invention relates to a bone regeneration material kit comprising: a particle comprising a calcium salt and having an inositol phosphate or salt thereof adsorbed on the surface; a particle comprising a bioabsorbable polymer; and an aqueous medium.Type: GrantFiled: August 8, 2014Date of Patent: May 9, 2017Assignees: Gunze Limited, Meiji University, Kanagawa Academy of Science and TechnologyInventors: Keishi Kiminami, Hidetoshi Arimura, Mamoru Aizawa, Minori Mizumoto, Toshiisa Konishi
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Patent number: 9605355Abstract: This method for producing anodic porous alumina such that an oxide coating film having a plurality of minute pores is formed at the surface of an aluminum substrate is characterized by containing: a step (a) for immersing the aluminum substrate in an electrolytic liquid resulting from mixing a plurality of acids; a step (b) for imposing a voltage on the aluminum substrate immersed in the electrolytic liquid; a step (c) for holding the aluminum substrate in the state of being immersed in the electrolytic liquid essentially without imposing a voltage on the aluminum substrate; and a step (d) for alternately repeating step (b) and step (c). By means of the present invention, it is possible using a simple device and with few steps to provide a method that easily produces anodic porous alumina such that an oxide coating film having a plurality of minute pores is formed at the surface of an aluminum substrate.Type: GrantFiled: December 9, 2013Date of Patent: March 28, 2017Assignees: MITSUBISHI RAYON CO., LTD., KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGYInventors: Hiroshi Onomoto, Jitsuo Hirohata, Eiko Okamoto, Yuji Matsubara, Masashi Ikawa, Hideki Masuda, Takashi Yanagishita
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Publication number: 20170073578Abstract: Provided are a transparent fluorescent sialon ceramic having fluorescence and optical transparency; and a method of producing the same. Such a transparent fluorescent sialon ceramic includes a sialon phosphor which contains a matrix formed of a silicon nitride compound represented by the formula Mx(Si,Ai)y(N,O)z (here, M represents at least one selected from the group consisting of Li, alkaline earth metals, and rare earth metals, 0?x/z<3, and 0<y/z<1) and a luminescent center element.Type: ApplicationFiled: March 6, 2015Publication date: March 16, 2017Applicants: Kanagawa Academy of Science and Technology, National University Corporation YOKOHAMA National UniversityInventors: Takuma Takahashi, Junichi Tatami, Yuki Sano, Takehiko Tanaka, Masahiro Yokouchi
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Patent number: 9572347Abstract: An agent for virus inactivation capable of exhibiting inactivation action based on structural destruction such as degradation and decomposition against viruses, which comprises a monovalent copper compound such as cuprous oxide, cuprous sulfide, cuprous iodide, and cuprous chloride as an active ingredient, and a virus inactivation material, which contains the agent for virus inactivation on a surface of a substrate and/or inside of the substrate.Type: GrantFiled: December 22, 2010Date of Patent: February 21, 2017Assignees: THE UNIVERSITY OF TOKYO, KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGYInventors: Kazuhito Hashimoto, Kayano Sunada, Masahiro Miyauchi, Xiaoqing Qiu, Yoshinobu Kubota, Hitoshi Ishiguro, Ryuichi Nakano, Jitsuo Kajioka, Yanyan Yao
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Publication number: 20150299758Abstract: The present invention provides a method for producing a microscopic object comprising locating a microscopic structure, formed of an organic substance, to be used as a mold on a substrate, depositing an intended element on a surface of the organic structure by a vacuum vapor deposition method or the like, and then decomposing and thus removing the organic structure as the mold by an ultraviolet-ozone process or the like to obtain the microscopic structure formed of only an intended element.Type: ApplicationFiled: November 8, 2012Publication date: October 22, 2015Applicant: Kanagawa Academy of Science and TechnologyInventors: Kenji YASUDA, Hyonchol KIM, Hideyuki TERAZONO, Akihiro HATTORI
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Patent number: 9120032Abstract: Provided is a microchip capable of integrating liquid evaporation as an operation on the microchip. In the microchip 10 having a gas flow path 13 inside, liquid is dispersed by capillary action and pooled in a pool portion 12 at a bottom of the gas flow path 13, and at least a part of the liquid pooled in the pool portion 12 is evaporated. As the capillary action is used, the liquid can be dispersed and pooled in the pool portion 12 at the bottom of the gas flow path 13 inside the microchip 10. Besides, the liquid pooled in the pool portion 12 remains in the pool portion by a surface tension even if gas is made to flow in the gas flow path 13 or the gas flow path is evacuated for evaporation. This enables highly efficient evaporation inside the microchip 10.Type: GrantFiled: October 30, 2008Date of Patent: September 1, 2015Assignees: JFE ENGINEERING CORPORATION, KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGYInventors: Katsuhiko Ohsaki, Shigeki Yamazaki, Takehiko Kitamori, Masaharu Ueno, Kazuma Mawatari, Yoshikuni Kikutani
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Patent number: 9109197Abstract: Provided is a device for concentrating and separating cells, which has a function for continuously concentrating cells; a function for then continuously arranging the concentrated cells in predetermined regions of a flow path; a function for simultaneously identifying shape and fluorescent emission in one-cell units on the basis of cell concentration and purification images, which serve to continuously separate and purify cells that have different properties in that they are either attracted to or repelled by an induction electrophoresis force of a predetermined frequency; and a function for identifying cells on the basis of this shape and fluorescent emission information and thereby separating and purifying the cells.Type: GrantFiled: March 31, 2010Date of Patent: August 18, 2015Assignees: Kanagawa Academy of Science and Technology, National University Corporation Tokyo Medical and Dental UniversityInventors: Kenji Yasuda, Masahito Hayashi, Akihiro Hattori
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Patent number: 9061086Abstract: A photocatalyst element structure includes a photocatalyst element that includes a flat photocatalyst sheet and an undulating photocatalyst sheet overlapped on the flat photocatalyst sheet. The flat photocatalyst sheet and the undulating photocatalyst sheet include a porous titanium foil having a non-periodic spongy structure impregnated with anatase titanium dioxide particles. The photocatalyst element structure can include a plurality of the photocatalyst elements so that the flat photocatalyst sheet and the undulating photocatalyst sheet alternate.Type: GrantFiled: August 5, 2010Date of Patent: June 23, 2015Assignees: U-VIX Corporation, Kanagawa Academy of Science and TechnologyInventors: Yuko Morito, Akira Fujishima, Takuji Horie, Kazuya Nakata, Taketoshi Murakami, Tsuyoshi Ochiai
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Publication number: 20150132766Abstract: The present invention provides a cell enrichment/purification device having a function of continuously enriching cells, a function of locating the cells in a particular area of a flow path in a continuous array after the cell enrichment, a function of recognizing the shape of the cells and fluorescence emission from the cells at the same time in units of one cell based on an image, and a function of recognizing the cells based on the information on the shape and fluorescence emission to separate/purify the cells.Type: ApplicationFiled: March 29, 2013Publication date: May 14, 2015Applicants: ON-CHIP CELLOMICS CONSORTIUM, KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGYInventors: Kenji Yasuda, Hyonchol Kim, Hideyuki Terazono, Akihiro Hattori
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Patent number: 9023294Abstract: Provided is a cell concentration and purification device, having: a function of continuously concentrating cells; a function of then subsequently disposing the cells continuously in a specific region of a channel; a function of simultaneously recognizing, based on an image, the shape and fluorescence emission of each single cell; and a function of recognizing the cells and then separating and purifying the same based on the data relating to the shape and fluorescence emission thereof.Type: GrantFiled: February 24, 2011Date of Patent: May 5, 2015Assignees: Kanagawa Academy of Science and Technology, National University Corporation Tokyo Medical and Dental University, On-Chip Cellonics Consortium Co., Ltd.Inventors: Hideyuki Terazono, Kenji Yasuda, Masahito Hayashi, Hiroyuki Takei, Akihiro Hattori
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Publication number: 20150079598Abstract: The present invention provides a high-speed gene amplification device including an additional mechanism that allows more stable temperature control, a pre-treatment mechanism that performs pre-treatment including a pre-PCR reaction reverse transcription reaction process that allows RNA detection, a melting curve analysis function, chip technology optimal for holding liquid droplets and performing optical measurements and an optical measurement function for a PCR reaction.Type: ApplicationFiled: March 5, 2013Publication date: March 19, 2015Applicants: KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY, ON-CHIP CELLOMICS CONSORTIUMInventors: Kenji Yasuda, Hideyuki Terazono, Hyonchol Kim, Akihiro Hattori
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Publication number: 20150053566Abstract: Disclosed herein are a stamper which has anodized alumina formed on the surface thereof and which will not cause macroscopic unevenness or color unevenness on the transcribed surface; a method for producing the same; and a method for producing a molded material without macroscopic unevenness or color unevenness on the transcribed surface thereof by using such a stamper. The stamper includes alumina which has a microasperity structure and which is formed by anodization on the surface of a prototype aluminum mold having an aluminum purity of 99.5% or more, an average crystal-grain diameter of 1 mm or less, and an arithmetic mean surface roughness Ra of 0.05 ?m or less. The use of this stamper enables the production of a molded material which does not have macroscopic unevenness or color unevenness on the transcribed surface thereof and which is suitable for use as an antireflection article and the like.Type: ApplicationFiled: September 15, 2014Publication date: February 26, 2015Applicants: MITSUBISHI RAYON CO., LTD., NIPPON LIGHT METAL COMPANY, LTD., KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGYInventors: Katsuhiro KOJIMA, Eiko OKAMOTO, Yoshihiro UOZU, Seiji TONE, Hideki Masuda, Takashi YANAGISHITA, Hiroaki KITA, Hisakazu ITO, Kota SHIRAI, Masayuki SAEKI
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Patent number: 8939752Abstract: A mold comprising alumina having a microscopic pattern, in which distances between adjacent recesses or salients therein are not longer than wavelength of visible light, formed by anodic oxidation on a surface of an aluminum pre-mold without a rolling mark, wherein height or depth difference at a crystal grain boundary is 300 nm or less.Type: GrantFiled: June 28, 2007Date of Patent: January 27, 2015Assignees: Mitsubishi Rayon Co., Ltd., Kanagawa Academy of Science and TechnologyInventors: Yoshihiro Uozu, Eiko Okamoto, Katsuhiro Kojima, Satoshi Sakuma, Hideki Masuda, Takashi Yanagishita
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Patent number: 8900854Abstract: The present invention provides a liquid reflux reaction control device comprising: a reaction vessel having one or a plurality of wells configured to accommodate a sample; a heat exchange vessel provided in contact with the reaction vessel so as to conduct heat to the reaction vessel, and comprising an inlet and an outlet respectively for introducing and draining a liquid of a predetermined temperature; a plurality of liquid reservoir tanks provided with a temperature-controllable heat source for maintaining liquids of predetermined temperatures; a tubular flow channel that connects the inlet and the outlet of the heat exchange vessel with the liquid reservoir tanks; a pump disposed on the tubular flow channel, and configured to circulate the liquid between the heat exchange vessel and the liquid reservoir tank; and a switching valve disposed on the tubular flow channel, and configured to control the flow of the circulating liquid, which controls the temperature of the reaction vessel to keep a desired temType: GrantFiled: March 31, 2010Date of Patent: December 2, 2014Assignees: Kanagawa Academy of Science and Technology, National University Corporation Tokyo Medical and Dental UniversityInventors: Hiroyuki Takei, Hideyuki Terazono, Kenji Yasuda
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Publication number: 20140248690Abstract: One embodiment provides a liquid reflux reaction control device comprising: a reaction vessel having one or a plurality of wells configured to accommodate a sample; a heat exchange vessel provided in contact with the reaction vessel so as to conduct heat to the reaction vessel, and comprising an inlet and an outlet respectively for introducing and draining a liquid of a predetermined temperature; a plurality of liquid reservoir tanks provided with a temperature-controllable heat source for maintaining liquids of predetermined temperatures; a tubular flow channel that connects the inlet and the outlet of the heat exchange vessel with the liquid reservoir tanks; a pump disposed on the tubular flow channel, and configured to circulate the liquid between the heat exchange vessel and the liquid reservoir tank; and a switching valve disposed on the tubular flow channel, and configured to control the flow of the circulating liquid.Type: ApplicationFiled: May 9, 2014Publication date: September 4, 2014Applicants: KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITYInventors: Hiroyuki Takei, Hideyuki TERAZONO, Kenji YASUDA
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Patent number: 8815604Abstract: A microchannel chip having a microchannel formed in a substrate and a gas-liquid phase separation microchannel whose upper part is covered with a porous film, the gas-liquid phase separation microchannel being connected to the downstream end of the microchannel and having a depth of 10 ?m to 100 ?m. Also, a gas-liquid phase separation method which is a method for separating a liquid-phase flow from a two-phase flow flowing through a microchannel by removing a gas phase, the two-phase flow composed of the gas phase and the liquid phase, which liquid phase flows in the periphery of the above-described microchannel and which gas phase flows interiorly of the liquid-phase flow.Type: GrantFiled: March 31, 2010Date of Patent: August 26, 2014Assignees: Institute of Microchemical Technology Co., Ltd., The University of Tokyo, Kanagawa Academy of Science and TechnologyInventors: Arata Aota, Yuko Kihira, Mari Sasaki, Takehiko Kitamori, Kazuma Mawatari
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Patent number: 8716047Abstract: When a p-layer 4 composed of GaN is maintained at ordinary temperature and TNO is sputtered thereon by an RF magnetron sputtering method, a laminated TNO layer 5 is in an amorphous state. Then, there is included a step of thermally treating the amorphous TNO layer in a reduced-pressure atmosphere where hydrogen gas is substantially absent to thereby crystallize the TNO layer. At the sputtering, an inert gas is passed through together with oxygen gas, and volume % of the oxygen gas contained in the gas passed through is 0.10 to 0.15%. In this regard, oxygen partial pressure is 5×10?3 Pa or lower. The temperature of the thermal treatment is 500° C. for about 1 hour.Type: GrantFiled: August 31, 2009Date of Patent: May 6, 2014Assignees: Toyoda Gosei Co., Ltd., Kanagawa Academy of Science and TechnologyInventors: Koichi Goshonoo, Miki Moriyama, Taro Hitosugi, Tetsuya Hasegawa, Junpei Kasai
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Publication number: 20130344124Abstract: An agent for virus inactivation capable of exhibiting inactivation action based on structural destruction such as degradation and decomposition against viruses, which comprises a monovalent copper compound such as cuprous oxide, cuprous sulfide, cuprous iodide, and cuprous chloride as an active ingredient, and a virus inactivation material, which contains the agent for virus inactivation on a surface of a substrate and/or inside of the substrate.Type: ApplicationFiled: December 22, 2010Publication date: December 26, 2013Applicants: KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY, THE UNIVERSITY OF TOKYOInventors: Kazuhito Hashimoto, Kayano Sunada, Masahiro Miyauchi, Xiaoqing Qiu, Yoshinobu Kubota, Hitoshi Ishiguro, Ryuichi Nakano, Jitsuo Kajioka, Yanyan Yao
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Publication number: 20130252848Abstract: In labeling a cell, and separating and collecting the cell according to a degree of the labeling using a cell separator, effects on the cell is minimized and the use of the collected cell is facilitated, thereby, when labeling a cell, the cell is labeled in the state where interaction of each cell is retained. In the labeling, a specific labeling material present on a surface of a target cell is taken in the cell via a transporter, and the cell is dispersed one by one to separate the same with a cell separator. Immediately after the separation, the cell is put in a solution not containing the specific labeling substance to remove the specific labeling substance taken in the cell. This series of steps is continuously conducted with a cell separation chip.Type: ApplicationFiled: January 31, 2013Publication date: September 26, 2013Applicants: KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY, Onchip Cellomics ConsortiumInventors: Kazunori Okano, Kenji Yasuda