Patents Assigned to Kawasumi Laboratories, Inc.
  • Patent number: 8852259
    Abstract: A tubular medical treatment instrument indwelling device for indwelling a stent graft expandable in the radial direction, includes a tubular sheath, a rod member configured to move forward and backward inside the sheath along the axial direction of the sheath, and a front tip provided in the forward end portion of the rod member and includes, formed therein, an engaging portion being engageable with an engagement portion provided in the stent graft. The engaging portion is formed in a position where it is hided inside the sheath when the forward end portion of the sheath is sealed with the front tip. The tubular medical treatment instrument indwelling device is capable of inhibiting damaging of a blood vessel or freeing of parietal thrombus/parietal atheroma from occurring.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: October 7, 2014
    Assignees: Katsuhiko OKA, Yoshihiko Yokoi, Kawasumi Laboratories, Inc.
    Inventors: Katsuhiko Oka, Yoshihiko Yokoi, Kazumi Akita
  • Patent number: 8821900
    Abstract: An object of the present invention is to provide an anti-adhesion material having sufficient in vivo degradability and excellent anti-adhesion characteristics, and also superior to conventional ones in terms of handling properties under wet conditions. The anti-adhesion material (1) of the present invention has a sheet-like base layer (10) containing a water soluble polymer (e.g., pullulan), a first cover layer (20) placed on a surface on one side of the base layer (10) and containing an aliphatic ester, and a second cover layer (30) placed on a surface on the other side of the base layer (10) and containing an aliphatic ester. The optical thickness of each of the first cover layer (20) and the second cover layer (30) is set to be 27 nm or greater and smaller than 160 nm.
    Type: Grant
    Filed: December 27, 2010
    Date of Patent: September 2, 2014
    Assignees: Kawasumi Laboratories, Inc., Shiga University of Medical Science
    Inventors: Toru Tani, Sumihiro Kamitani, Tomokazu Mukai
  • Publication number: 20130172826
    Abstract: Provided is a safety apparatus for medical needles which is free from accidental exposure of an acuate top end contaminated with a blood, etc. from a lower portion thereof. The safety apparatus includes a shield member (3) having a shield hub (35), a shield member connection hub (40H) and leg portions (31,32), the leg portions (31,32) being capable of extending from the first folded position to the second extended position, a needle (21) being to be inserted in the space (40S) of the above shield member connection hub (40H) when the leg portions (31,32) are in the first folded position, the wall (43DW) of the above slide member (42) being to be pulled into the shield member connection hub (40H) when the leg portions (31,32) are extended up to the second extended position, whereby the apparatus is so formed that it can prevent the distal end (23) of the needle (21) from being exposed to an outside.
    Type: Application
    Filed: December 14, 2012
    Publication date: July 4, 2013
    Applicant: KAWASUMI LABORATORIES, INC.
    Inventor: KAWASUMI LABORATORIES, INC.
  • Publication number: 20120301515
    Abstract: An object of the present invention is to provide an anti-adhesion material having sufficient in vivo degradability and excellent anti-adhesion characteristics, and also superior to conventional ones in terms of handling properties under wet conditions. The anti-adhesion material (1) of the present invention has a sheet-like base layer (10) containing a water soluble polymer (e.g., pullulan), a first cover layer (20) placed on a surface on one side of the base layer (10) and containing an aliphatic ester, and a second cover layer (30) placed on a surface on the other side of the base layer (10) and containing an aliphatic ester. The optical thickness of each of the first cover layer (20) and the second cover layer (30) is set to be 27 nm or greater and smaller than 160 nm.
    Type: Application
    Filed: December 27, 2010
    Publication date: November 29, 2012
    Applicants: SHIGA UNIVERSITY OF MEDICAL SCIENCE, KAWASUMI LABORATORIES, INC.
    Inventors: Toru Tani, Sumihiro Kamitani, Tomokazu Mukai
  • Publication number: 20120177936
    Abstract: [Object] To provide a medical instrument capable of more effectively inhibiting a cracking and separation than conventional ones. [Solution Means] A stent comprising a substrate layer 10 of which at least the surface is composed of a metal material, a carbon compound layer 12 that is formed so as to coat the surface of the substrate layer 10 and that contains at least one metal element, a first DLC layer 14 that is formed so as to coat the surface of the carbon compound layer 12 and that is free of fluorine, and a second DLC layer 16 that is formed so as to coat the surface of the first DLC layer 14 and that contains fluorine. The stent being constituted to satisfy the relationship defined by the expression of “A1>A2>A3”, wherein A1 is a surface free energy of the carbon compound layer 12, A2 is a surface free energy of the first DLC layer 14, and A3 is a surface free energy of the second DLC layer 16.
    Type: Application
    Filed: August 12, 2010
    Publication date: July 12, 2012
    Applicant: KAWASUMI LABORATORIES, INC.
    Inventors: Tetsuya Suzuki, Kazunori Murakami
  • Publication number: 20120116413
    Abstract: A tubular medical treatment instrument indwelling device for indwelling a stent graft expandable in the radial direction, includes a tubular sheath, a rod member configured to move forward and backward inside the sheath along the axial direction of the sheath, and a front tip provided in the forward end portion of the rod member and includes, formed therein, an engaging portion being engageable with an engagement portion provided in the stent graft. The engaging portion is formed in a position where it is hided inside the sheath when the forward end portion of the sheath is sealed with the front tip. The tubular medical treatment instrument indwelling device is capable of inhibiting damaging of a blood vessel or freeing of parietal thrombus/parietal atheroma from occurring.
    Type: Application
    Filed: May 25, 2010
    Publication date: May 10, 2012
    Applicants: KATSUHIKO OKA, KAWASUMI LABORATORIES, INC, YOSHIHIKO YOKOI
    Inventors: Katsuhiko Oka, Yoshihiko Yokoi, Kazumi Akita
  • Publication number: 20120095368
    Abstract: An object is to provide a blood collection set configured such that a sampling holder and a needlestick-preventive needle cover are more difficult to disengage from each other than conventional. A blood collection set (500) includes a sampling holder (100) and a needlestick-preventive needle cover (200). The sampling holder (100) includes a tubular body (110), a lid (130), and a fitting portion (140) having a circumferential rib as a rib portion and a catching portion. The needlestick-preventive needle cover (200) includes an engaging portion (250) that is engageable with the catching portion of the sampling holder (100).
    Type: Application
    Filed: June 28, 2010
    Publication date: April 19, 2012
    Applicant: KAWASUMI LABORATORIES, INC.
    Inventors: Masayuki Morita, Masatoshi Watanabe, Takenori Sakura
  • Patent number: 8137393
    Abstract: A stent graft indwelling device (1) comprising a dilator (10) and a sheath (30) in which the dilator (10) and a stent graft (60) are to be loaded, the stent graft indwelling device (1) having a wire (40) or a fixed chip (20) as means for adjusting the insertion angle and/or indwelling site of the stent graft (60) when the stent graft (60) is released from the sheath (30) in a diseased part by this indwelling device, so that the insertion angle and indwelling site can be finely adjusted in a blood vessel in a semi-expansion state where the stent graft is not completely expanded.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: March 20, 2012
    Assignees: Kawasumi Laboratories, Inc.
    Inventors: Shin Ishimaru, Yoshihiko Yokoi
  • Patent number: 8118786
    Abstract: A guarded medical winged needle assembly for safely and securely encasing a winged needle without any complicated operation, includes a cylindrical needle cover 1 having a forward section 2, a middle section 3 and a backward section 4, the middle section 3 having an opening 5 formed at a bottom thereof, the backward section 4 having a slit 7, and a winged needle 21 having a pair of wings 24 fitted to on both sides of a hub 23, a needle 22 provided before said hub 23 and a tube T fitted to a backward portion of said hub 23, and said winged needle 21 being slidably housed and protected in said needle cover 1, (A) an engaging member 27, 28 being fitted to said tube T, or (B) an engaging member 30 being fitted to a backward portion of said hub 23, said winged needle thereby being fixable when housed in said needle cover.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: February 21, 2012
    Assignee: Kawasumi Laboratories, Inc.
    Inventors: Seiichi Ono, Kaoru Maneyama
  • Patent number: 7985251
    Abstract: A stent having a generally tubular body formed of ring units formed of a plurality of cells each and expandable in the radial direction, wherein each ring unit is constituted of cells connected to one another above and below, arranged to surround the center line of the stent, the ring units are arranged in the axial direction of the stent, and are connected with connector portions, each connector portion is formed of curved portions each having an arch and a generally linear portion continued thereto, 3 to 8 cells are arranged in the axial direction per 10 mm of the length of the stent, and the ratio of the length of the cell in the axial direction and the length of the connector portion is determined such that on the basis that when the length of the cell is 100, that of the connector portion 50 to 100, thereby securing flexibility and radial sustaining force.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: July 26, 2011
    Assignees: Kawasumi Laboratories, Inc.
    Inventors: Ken Ikeuchi, Kouji Mori, Hiroo Iwata, Kazuaki Mitsudou, Hiroaki Nomiyama, Yoshiharu Yoshikawa, Masatoshi Watanabe, Shuzou Yamashita, Kazunori Murakami
  • Patent number: 7794492
    Abstract: A stent formed in a shape of a generally tubular body having a central axis. The stent has a spring function with which the tubular body is diameter-contractible toward the central axis, and the tubular body is expandable to an initial diameter after contraction. The stent maintains a configuration curved along a longitudinal direction of the stent when the stent is not inserted in a sheath. The stent is elongated in a form of a generally straight line along the longitudinal direction when the stent is inserted into the sheath. The stent, being housed in a sheath in the form of a generally straight line, is inserted into a diseased part together with the sheath, is released from the sheath, and radially expands, outwardly after release, to restore and maintain a configuration curved along the longitudinal direction of the stent.
    Type: Grant
    Filed: May 19, 2003
    Date of Patent: September 14, 2010
    Assignees: Kawasumi Laboratories, Inc., Mani Inc.
    Inventors: Shin Ishimaru, Yoshihiko Yokoi, Masaaki Matsutani, Yasushi Hashimoto
  • Patent number: 7736393
    Abstract: Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/?-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater, 2<L(LA)<[LA%/(LA%+GA%+CL%)]×X×0.058??(1) 1<L(GA)<[GA%/(LA%+GA%+CL%)]×X×0.58??(2) 1<L(CL)<[CL%/(LA%+GA%+CL%)]×X×0.
    Type: Grant
    Filed: April 18, 2005
    Date of Patent: June 15, 2010
    Assignee: Kawasumi Laboratories, Inc.
    Inventors: Noriaki Shirahama, Tomokazu Mukai, Takao Okada, Yukari Imamura, Yoshimichi Fujiyama
  • Publication number: 20100036363
    Abstract: In a microcatheter, a shaft tube thereof is sectioned into a proximal zone, an intermediate zone, and a distal zone from a connector to the forward end thereof, each being formed of a multilayered tube, including three types of multilayered tubes different in hardness, an inner layer extending along all the zones from the proximal zone to the distal zone of the shaft tube, and a reinforcing material being fitted to the outer circumference of the inner layer, a first outer layer extending along all the zones from the proximal zone to the distal zone of the shaft tube so as to coat, and adhere to, the inner layer and the reinforcing material, to form a base layer structure of the inner layer/reinforcing material/first outer layer, a third outer layer coating the first outer layer of the base layer structure in the proximal zone, a second outer layer coating the first outer layer of the base layer structure in the intermediate zone.
    Type: Application
    Filed: September 13, 2006
    Publication date: February 11, 2010
    Applicant: KAWASUMI LABORATORIES , INC.
    Inventors: Masatoshi Watanabe, Koji Horikawa
  • Publication number: 20080039925
    Abstract: A stent graft indwelling device (1) comprising a dilator (10) and a sheath (30) in which the dilator (10) and a stent graft (60) are to be loaded, the stent graft indwelling device (1) having a wire (40) or a fixed chip (20) as means for adjusting the insertion angle and/or indwelling site of the stent graft (60) when the stent graft (60) is released from the sheath (30) in a diseased part by this indwelling device, so that the insertion angle and indwelling site can be finely adjusted in a blood vessel in a semi-expansion state where the stent graft is not completely expanded
    Type: Application
    Filed: April 18, 2005
    Publication date: February 14, 2008
    Applicants: Shin ISHIMARU, KAWASUMI LABORATORIES, INC.
    Inventors: Shin Ishimaru, Yoshihiko Yokoi
  • Patent number: 7291135
    Abstract: A winged angled needle assembly has a hub to which a proximal end portion of an angled needle having a sharpened tip portion is joined and a pair of wings attached to both sides of the hub and further includes a fixing member attached so as to support the wings and an extensible, contractible needle guard disposed between the hub and the fixing member so as to connect these two members. The guard extends in the direction from the proximal end portion to the sharpened tip portion of the angled needle when extended, so that the tip portion can be encased in said guard simultaneously with pulling the angled needle out of an implanted port. The guard has an exposure prevention mechanism attached thereto and is externally stopped, so that the sharpened tip portion is kept from exposing once it is encased in the guard. The angled needle can have a length as required regardless of the length of the wings.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: November 6, 2007
    Assignee: Kawasumi Laboratories, Inc.
    Inventor: Seiichi Ono
  • Publication number: 20070239118
    Abstract: A guarded medical winged needle assembly for safely and securely encasing a winged needle without any complicated operation, includes a cylindrical needle cover 1 having a forward section 2, a middle section 3 and a backward section 4, the middle section 3 having an opening 5 formed at a bottom thereof, the backward section 4 having a slit 7, and a winged needle 21 having a pair of wings 24 fitted to on both sides of a hub 23, a needle 22 provided before said hub 23 and a tube T fitted to a backward portion of said hub 23, and said winged needle 21 being slidably housed and protected in said needle cover 1, (A) an engaging member 27, 28 being fitted to said tube T, or (B) an engaging member 30 being fitted to a backward portion of said hub 23, said winged needle thereby being fixable when housed in said needle cover.
    Type: Application
    Filed: March 29, 2006
    Publication date: October 11, 2007
    Applicant: KAWASUMI LABORATORIES, INC.
    Inventors: Seiichi Ono, Kaoru Maneyama, Jack Pavlo
  • Publication number: 20070233275
    Abstract: Provided are an artificial dura mater having a laminated constitution of at least two layers of in vivo degradable polymers, at least one layer of them being a substrate layer, the substrate layer being formed of a lactic acid/glycolic acid/?-caprolactone copolymer, the copolymer having a component molar ratio of 60-85:3-15:10-30 mol % and the copolymer having an average chain length that satisfies the following expressions (1) to (3) and a process for the production thereof, and when this artificial dura mater is used, no liquid leakage is caused since the bloating of suture holes is small, and the period of time for which it retains its strength is suitably a little longer than the period of time required for the regeneration of an autodura mater, 2<L(LA)<[LA %/(LA %+GA %+CL %)]×X×0. 058 ??(1) 1<L(GA)<[GA %/(LA %+GA %+CL %)]×X×0. 58 ??(2) 1<L(CL)<[CL %/(LA %+GA %+CL %) ×X×0.
    Type: Application
    Filed: April 18, 2005
    Publication date: October 4, 2007
    Applicant: KAWASUMI LABORATORIES, INC.
    Inventors: Noriaki Shirahama, Tomokazu Mukai, Takao Okada, Yukari Imamura, Yoshimichi Fujiyama
  • Patent number: 7179285
    Abstract: A stent (1) formed into a generally or substantially tubular body and expandable radially outward from inside of the tubular body, wherein cells (6) are connected vertically and so arranged as to surround the central axis (C1) of the stent (1) and thereby to form annular units (4), the annular units (4) are extended along the axis of the stent (1), adjacent annular units (4) are connected at least at one portion by a connecting part (5), each of the cells (6) has at least one bent portion, and the angle of the bent portion after expansion of the tubular body until the diameter becomes 2.5 mm is larger than 30°. The stent ensures a high flexibility and radial support force, enhances the blood vessel expandability, and suppresses the foreshortening phenomenon and the flare phenomenon.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: February 20, 2007
    Assignees: Kawasumi Laboratories, Inc.
    Inventors: Takeshi Ikeuchi, Kouji Mori, Hiroo Iwata, Kazuaki Mitsudou, Hiroaki Nomiyama, Yoshiharu Yoshikawa, Masatoshi Watanabe
  • Patent number: 7147905
    Abstract: A laminate comprising at least a surface layer (I) and an adjacent layer (II) thereto, characterized in that the surface layer (I) comprises a cross-linked copolymer formed by cross-linking a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound, and the adjacent layer (II) comprises a hydrogenated copolymer formed by hydrogenating a copolymer prepared by using as monomers at least one vinyl aromatic compound and at least one conjugated diene compound; a multilayer tube comprising the laminate; and a medical device comprising the laminate, and/or the multilayer tube.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: December 12, 2006
    Assignees: Kuraray Co., Ltd., Kawasumi Laboratories, Inc.
    Inventors: Motohiro Fukuda, Naoto Fukuhara, Yukihiro Fujieda, Toshihide Nakashima, Koji Inai, Toshiji Ichikawa, Akira Ishida
  • Publication number: 20060047252
    Abstract: A winged angled needle assembly (1) has a hub (3) to which a proximal end portion (2?) of an angled needle (2) having a sharpened tip portion (2?) is joined and a pair of wings (4) attached to both sides of the hub (3) and further includes a fixing member (5) attached so as to support the wings and an extensible, contractible needle guard (6) disposed between the hub (3) and the fixing member (5) so as to connect these two members. The guard (6) extends in the direction from the proximal end portion (2?) to the sharpened tip portion (2?) of the angled needle (2) when extended, so that the tip portion (2?) can be encased in said guard (6) simultaneously with pulling the angled needle (2) out of an implanted port. The guard (6) has exposure prevention means attached thereto and is externally stopped, so that the sharpened tip portion (2?) is kept from exposing once it is encased in the guard. The angled needle (2) can have a length as required regardless of the length of the wings.
    Type: Application
    Filed: August 18, 2005
    Publication date: March 2, 2006
    Applicant: KAWASUMI LABORATORIES, INC.
    Inventor: Seiichi Ono