Abstract: A sampling interface may comprise an inlet port, an outlet port, and a sampling chamber between the inlet port and the outlet port. The apparatus may also comprise a sampling port and at least one split seal between the sampling port and the sampling chamber. The split seal may comprise a first sealing member and a second sealing member that converge to a sealing line. The apparatus may additionally include at least one fluid collection channel disposed interior to the split seal. A lateral flow strip for sampling fluid removed from a tissue site may comprise an acquisition surface and a migration medium fluidly coupled to the acquisition surface. At least one test medium may be fluidly coupled to the migration medium, and a liquid-impermeable cover may enclose the migration medium and the test medium. The acquisition surface is preferably not enclosed.

Abstract: A system is described herein that can irrigate a tissue site using negative-pressure. The system may include a tissue interface configured to be placed adjacent to the tissue site, and a sealing member configured to be placed over the tissue interface to form a sealed space. The system may also include a negative-pressure source configured to be fluidly coupled to the sealed space and a fluid source. The system may further include an irrigation valve. The irrigation valve can have a fluid inlet configured to be fluidly coupled to the fluid source. The irrigation valve can also have a fluid outlet configured to be fluidly coupled to the sealed space. The irrigation valve may also include a clamp configured to be actuated by the negative-pressure source to regulate fluid flow from the fluid source through the fluid outlet.

Abstract: Fluid supply systems and methods for therapeutic fluid delivery systems, including those used for negative pressure wound therapy (NPWT) systems and methods.

Abstract: A dressing for treating tissue with negative pressure may be a composite of dressing layers, including a release film, perforated gel layer, a perforated polymer film, a manifold, and an adhesive cover. A method of manufacturing the dressing may comprise providing a first layer, such as the gel layer, on a substrate, perforating the first layer on the substrate to create a plurality of apertures in the first layer, and creating an index of the plurality of apertures in the first layer. A laser can be calibrated based on the index. A second layer, such as the polymer film, may be coupled to the first layer, and a plurality of slots can be cut in the second layer with the laser. Each of the slots can be cut through one of the apertures in the first layer based on the index.

Abstract: In some embodiments, a dressing assembly may include a dressing bolster, an interface seal, and a base layer. The dressing bolster may include a first side, a second side, and a periphery. The interface seal may be coupled at the periphery of the dressing bolster. The base layer may include a base layer flange configured to be coupled to the dressing and to extend beyond the periphery of the dressing bolster. The dressing assembly may be suitable for treating a tissue site with reduced pressure and for creating an apposition force between a first portion of the tissue site and a second portion of the tissue site. Other systems, apparatus, and methods are disclosed.

Abstract: Systems, methods, and apparatuses for generating and releasing iodine are described. Some embodiments may include a dressing member including a plurality of iodine-forming reagents and a water-swellable material. In some embodiments, the dressing member may include water-swellable fibers. The water-swellable fibers may each include a water-swellable material in which iodine-forming reagents are dispersed. As liquid comes into contact with and is absorbed by the water-swellable material, the iodine-forming reagents may come into contact with each other, causing an iodine-forming reaction to occur, producing iodine.

Abstract: According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a wound dressing is provided comprising a scaffold coated with a biologically active composition comprising a lipoic acid derivative. In a further embodiment, a system is provided for treating a tissue site of a patient, the system comprising a reduced-pressure source to supply reduced pressure, a manifold to distribute reduced pressure to a tissue site and a scaffold coated with a biologically active composition comprising a lipoic acid derivative. Methods for producing such a system and scaffold are also disclosed.

Abstract: Methods, apparatuses, and systems for promoting re-epithelialization as an aspect of wound healing are presented. A re-epithelialization dressing for use with reduced pressure has a moist tissue-interface layer, a manifold member, and a sealing member. The moist tissue-interface layer has a plurality of apertures. The moist tissue-interface layer is for disposing adjacent to the wound and provides a moisture balance (i.e., provides moisture when the wound is dry and receives moisture when the wound site is substantially wet). The reduced pressure, apertures, and moist tissue-interface layer help with liquid management and otherwise promote re-epithelialization. Other systems, apparatuses, and methods are presented.

Abstract: Systems, methods, and apparatuses for irrigating a tissue site are described. The system can include a tissue interface and a sealing member configured to be placed over the tissue site to form a sealed space, and a negative-pressure source fluidly coupled to the sealed space. The system includes an irrigation valve having a housing, a piston disposed in the housing, a fluid inlet to fluidly couple a fluid inlet chamber to a fluid source, and a fluid outlet to fluidly couple a fluid outlet chamber to the sealed space. A piston passage extends through the piston and fluidly couples the fluid inlet chamber and the fluid outlet chamber, and a biasing member is coupled to the piston to bias the irrigation valve to a closed position. The negative-pressure source is configured to move the piston between the closed position and an open position to draw fluid to the sealed space.

Abstract: Systems, methods, and dressing are presented for treating a tunnel wound on a patient. In one instance, a reduced-pressure, tunnel-wound dressing includes a longitudinal core member formed from a closed-cell foam that is surrounded by a first longitudinal concentric member formed from a manifolding material. When subjected to reduced pressure, the longitudinal core member expands and the first longitudinal concentric member compresses. These actions create intimate contact between the tunnel wound and the dressing, oppose collapse of the tunnel, and when reduced pressure is removed provide clearance to remove the dressing. Other embodiments are presented.

Abstract: The present invention generally relates to methods for applying a skin graft. Methods of the invention involve harvesting an epidermal skin graft, and applying the epidermal skin graft to a recipient site such that the basal layer of the skin graft makes direct contact with the recipient site.

Abstract: A combination hanger arm extension and pump cover device can be used with an instillation unit. The device includes a body portion that has a first end and a second end. A hook extends from the first end, and a tab extends from the body proximate the hook. A panel is disposed proximate the second end. A substantially rectangular sleeve extends at least partially through the body. The sleeve is disposed between the first and second end.

Abstract: Skin graft harvesting systems and methods are disclosed that utilize sensors to automate the harvesting of skin grafts or assist a user in deciding when the skin graft is ready to be harvested. Such systems and methods can reduce the burden of visual observation and ensure greater reliability and consistency of the grafts. The invention is particularly useful with harvesters that rely upon suction and/or heating to raise a plurality of small or “micro” blisters simultaneously.

Abstract: Systems, methods, and apparatuses for treating a tissue site with reduced pressure are described. The system includes a manifold configured to be placed adjacent the tissue site, and a sealing member configured to be placed over the tissue site and the manifold. The system also includes a reduced-pressure source fluidly coupled to the manifold through the sealing member. The system further includes a pouch having an upstream layer having a first thickness, a downstream layer having a second thickness, and an absorbent member enclosed between the upstream layer and the downstream layer. The second thickness is greater than the first thickness. The upstream layer may have a hydrophilic side adjacent the absorbent member, and the downstream layer may have a hydrophobic side adjacent the absorbent member.

Abstract: Systems, methods, and apparatus are provided for detecting leaks in systems for treating a patient with reduced pressure. In one instance, a system includes a distribution manifold for disposing proximate to the tissue site and a sealing member for disposing over the distribution manifold and at least a portion of intact epidermis of the patient. The sealing member has at least a portion that is substantially transparent. The system further includes a reduced-pressure source associated with the distribution manifold for providing reduced pressure to the distribution manifold and a leak-detection member sized and configured to substantially surround the distribution manifold. The leak-detection member includes a detection material that develops a color contrast when a portion is exposed to air and a portion is not exposed to air. The leak detection member works with even low flow systems. Other systems, methods, and apparatus are presented.

Abstract: A system for treating a deep abdominal wound. The system includes a wound dressing. The wound dressing includes a visceral-protective layer, a compressive layer, and a sealing layer. The visceral-protective layer is configured to be positioned in an open abdomen. The compressive layer is configured to be disposed proximate to the visceral-protective layer. The compressive layer includes a pattern of voids configured for anisotropic collapse of the compressive layer when under negative pressure. The sealing layer is configured to form a sealed space in the open abdomen. A negative pressure source configured to provide negative pressure to the compressive layer.

Abstract: A reduced-pressure system for treating a tissue site on a patient includes a distribution manifold that adheres to a tissue site to allow retention without external support. The distribution manifold includes a porous member and a tissue-fixation element. The tissue-fixation element maintains the porous member substantially adjacent to the tissue site while a sealing member is applied. In one instance, the tissue-fixation element is a soluble adhesive that partially covers either the tissue-facing side of the porous member or a tissue-facing side of a fluid-permeable substrate layer that is on the tissue-facing side of the porous member. Other systems, distributions manifolds, and methods are presented.

Abstract: An apparatus and method for managing reduced pressure at a tissue site are disclosed. The apparatus comprises a pump for supplying reduced pressure to the tissue site, a motor coupled to the pump to propel the pump, and a drive system electrically coupled to the motor that includes a power source that provides a source of direct current power to the motor during an operational period at a substantially constant current and of sufficient magnitude to supply a targeted reduced pressure during the operational period. The drive system also includes a controller that monitors the pump's loading on the motor by measuring the voltage across the motor to determine whether the motor voltage remains within a predetermined operational range of voltages necessary for maintaining the reduced pressure supplied by the pump proximate to the targeted reduced pressure without directly measuring the reduced pressure using a pressure sensor.

Abstract: Disclosed herein are devices and methods for reduced pressure tissue therapy. Some variations of suction devices for reduced pressure tissue therapy comprise a housing, a suction force generating mechanism located within the housing, and a storage module configured to retain tissue exudates. In some variations, the storage module includes a sleeve configured to collect tissue exudates. The sleeve may include a support element to help maintain the lateral structural integrity of the sleeve and/or retain the cross-sectional geometry of the sleeve under negative pressure. In use, the storage module may reduce sanitary and/or biohazard risks by preventing the exudates from contacting the housing and/or suction force generating mechanism. The storage module is configured to be replaced so that the housing and suction force generating mechanism can be used for more than one session.

Abstract: In some illustrative embodiments, a system suitable for treating a tissue site may include a dressing, a low-profile conduit, a conduit interface, and a reduced-pressure source. The dressing may be adapted for positioning at the tissue site. The low-profile conduit may be adapted for fluidly coupling to the dressing. The low-profile conduit may include a manifold and a sealing member encapsulating the manifold. The conduit interface may be adapted for fluidly coupling to the low-profile conduit. The conduit interface may be in fluid communication with the dressing through the low-profile conduit. The reduced-pressure source may be adapted for fluid communication with the conduit interface. Other systems, devices, and methods are disclosed.