Patents Assigned to Kirin Holdings Kabushiki Kaisha
  • Patent number: 10568347
    Abstract: To provide a bottled carbonated drink including a sweetener and a caramel composition, wherein the drink contains an indigestible dextrin and the amount of 4-methylimidazole in the drink is less than 200 ppb. The drink is a bottled carbonated drink of which foam is stabilized.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: February 25, 2020
    Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, KIRIN BEVERAGE KABUSHIKI KAISHA
    Inventors: Hiroyuki Naganuma, Kenichiro Yamamoto, Yuko Yotsumoto, Hideyuki Wakabayashi
  • Patent number: 10525088
    Abstract: It is an object of the present invention to provide a lactic acid bacterial immunopotentiating activity-increasing composition that increases the immunopotentiating activity of lactic acid bacteria having immunopotentiating activity; and a method for increasing the immunopotentiating activity of lactic acid bacteria using the composition; and a composition comprising both of lactic acid bacteria having an immunopotentiating activity and a lactic acid bacterial immunopotentiating activity-increasing composition, wherein the immunopotentiating activity of the lactic acid bacteria is increased. The present invention relates to a composition comprising lactic acid bacteria having an immunopotentiating activity and a lactic acid bacterial immunopotentiating activity-increasing composition comprising an ester compound of a polyol and a saturated fatty acid as an active ingredient.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: January 7, 2020
    Assignee: Kirin Holdings Kabushiki Kaisha
    Inventors: Masaya Kanayama, Kyoko Tazumi
  • Publication number: 20190374587
    Abstract: An object of the present invention is to provide a composition for preventing visual dysfunction caused by exposure to light, such as so-called blue light. The present invention provides a composition comprising a lactic acid bacterium as an active ingredient for use in suppressing or improving conditions caused by retinal inflammation resulting from light damage. Eye discomfort is an exemplary condition caused by retinal inflammation resulting from light damage.
    Type: Application
    Filed: September 8, 2017
    Publication date: December 12, 2019
    Applicant: Kirin Holdings Kabushiki Kaisha
    Inventors: Toshihide KURIHARA, Yuji MORITA, Kenta JONAI, Daisuke FUJIWARA
  • Patent number: 10487397
    Abstract: An object of the present disclosure is to provide a gas barrier plastic molded body which is excellent in gas barrier properties and transparency and a method for producing the same. A gas barrier plastic molded body 90 according to the present disclosure includes a plastic molded body 91 and a gas barrier thin film 92 provided on a surface of the plastic molded body 91, and in the gas barrier plastic molded body, the gas barrier thin film 92 contains silicon (Si), carbon (C), and oxygen (O) as constituent elements and has a region, in a which a main peak is observed, at a peak appearance position of binding energy of Si—C when the gas barrier thin film is subjected to an X-ray photoelectron spectroscopic analysis under Condition (1). Condition (1): a measurement range is set to 95 to 105 eV.
    Type: Grant
    Filed: April 5, 2016
    Date of Patent: November 26, 2019
    Assignee: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventor: Hiroyasu Tabuchi
  • Patent number: 10434133
    Abstract: An oligopeptide having a good anti-inflammation effect on microglia has been found, and based on this finding, a composition to be used for suppressing the inflammation of microglia is provided. Inflammation suppression action of a dipeptide has been comprehensively analyzed using the proinflammatory cytokine production of microglia as an indicator. As a result, it has been revealed that an oligopeptide including the sequence LH, DV or MH has a good inflammation suppression effect. The composition containing any of these oligopeptides can provide a composition having the effect of suppressing the excessive inflammatory action of microglia.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: October 8, 2019
    Assignee: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventors: Yasuhisa Ano, Masahiro Kita
  • Publication number: 20190192584
    Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.
    Type: Application
    Filed: March 1, 2019
    Publication date: June 27, 2019
    Applicant: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventors: Daisuke FUJIWARA, Kenta Jonai, Tetsu Sugimura
  • Publication number: 20190128874
    Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.
    Type: Application
    Filed: December 13, 2018
    Publication date: May 2, 2019
    Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO
    Inventors: Toshikazu TSUJI, Kumiko IKADO, Seiichi UCHIYAMA, Kyoko KAWAMOTO
  • Publication number: 20190113505
    Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 18, 2019
    Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO
    Inventors: Toshikazu TSUJI, Kumiko IKADO, Seiichi UCHIYAMA, Kyoko KAWAMOTO
  • Patent number: 10220060
    Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: March 5, 2019
    Assignee: Kirin Holdings Kabushiki Kaisha
    Inventors: Daisuke Fujiwara, Kenta Jonai, Tetsu Sugimura
  • Patent number: 10191035
    Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: January 29, 2019
    Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO
    Inventors: Toshikazu Tsuji, Kumiko Ikado, Seiichi Uchiyama, Kyoko Kawamoto
  • Patent number: 10138491
    Abstract: An object of the present invention is to provide DNA of a glycoalkaloid biosynthetic enzyme of a solanaceous plant (Solanaceae) such as a potato. The present invention relates to a protein having glycoalkaloid biosynthetic enzyme activity of a solanaceous plant such as a potato and a method for producing/detecting a novel organism using a gene encoding the protein.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: November 27, 2018
    Assignee: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventors: Naoyuki Umemoto, Katsunori Sasaki
  • Patent number: 10053701
    Abstract: Provided is DNA of biosynthetic enzyme of glycoalkaloid of solanaceous plant (Solanaceae) such as potato. Provided are a protein having activity on a biosynthetic enzyme of glycoalkaloid of solanaceous plant such as potato, and a method of creating and assaying a novel organism using a gene encoding the protein.
    Type: Grant
    Filed: November 19, 2012
    Date of Patent: August 21, 2018
    Assignee: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventor: Naoyuki Umemoto
  • Patent number: 9765353
    Abstract: Provided are the DNA of a glycoalkaloid biosynthetic enzyme of solanaceous plants (Solanaceae) such as potato, solanaceous plants producing no glycoalkaloids, and a method of producing a cultivar with a reduced risk of accumulating glycoalkaloids, which involves crossing plants in which the expression of an oxidase gene involved in glycoalkaloid biosynthesis is suppressed or the activity of the enzyme is lowered, as mother plants, and screening progeny resulting from the crossing.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: September 19, 2017
    Assignee: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventor: Naoyuki Umemoto
  • Patent number: 9737077
    Abstract: This invention relates to: a method for controlling the sexuality of hop, comprising applying a chemical to a hop female plant once or more and forming a fertile male flower capable of forming pollen on the female plant, wherein the chemical reduces a reaction with endogenous ethylene in the female plant; an embryo or seed, hop plant, and cone, capable of being obtained through the method; a method of screening for a hop plant; and a method of producing a hop plant variety.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: August 22, 2017
    Assignee: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventors: Takayuki Momma, Naoyuki Umemoto
  • Patent number: 9688995
    Abstract: This invention provides a plant belonging to the family Solanaceae that does not produce cholesterols, including glycoalkaloids. This invention concerns a protein having activity of an enzyme that reduces position 24 of the steroid skeleton of a plant belonging to the family Solanaceae, a novel plant in which a gene encoding such protein is suppressed, and a method for producing and testing such plant.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: June 27, 2017
    Assignee: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventors: Naoyuki Umemoto, Masako Otsuka
  • Publication number: 20170121727
    Abstract: An object of the present invention is to provide DNA of a glycoalkaloid biosynthetic enzyme of a solanaceous plant (Solanaceae) such as a potato. The present invention relates to a protein having glycoalkaloid biosynthetic enzyme activity of a solanaceous plant such as a potato and a method for producing/detecting a novel organism using a gene encoding the protein.
    Type: Application
    Filed: January 18, 2017
    Publication date: May 4, 2017
    Applicant: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventors: Naoyuki UMEMOTO, Katsunori SASAKI
  • Publication number: 20170106028
    Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.
    Type: Application
    Filed: December 2, 2016
    Publication date: April 20, 2017
    Applicant: KIRIN HOLDINGS KABUSHIKI KAISHA
    Inventors: Daisuke FUJIWARA, Kenta JONAI, Tetsu SUGIMURA
  • Publication number: 20170037345
    Abstract: The present invention relates to a hop extract having a reduced bitter taste which shows a fat absorption suppressing effect. More specifically the present invention relates to a hop extract oxidation-reaction product obtained by an oxidation-reaction of a hop extract.
    Type: Application
    Filed: October 24, 2016
    Publication date: February 9, 2017
    Applicant: Kirin Holdings Kabushiki Kaisha
    Inventors: Yoshimasa TANIGUCHI, Yumie KOBAYASHI, Fumitoshi MANABE, Mikio KATAYAMA
  • Patent number: 9549956
    Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: January 24, 2017
    Assignee: Kirin Holdings Kabushiki Kaisha
    Inventors: Daisuke Fujiwara, Kenta Jonai, Tetsu Sugimura
  • Patent number: 9512389
    Abstract: The present invention relates to a hop extract having a reduced bitter taste which shows a fat absorption suppressing effect. More specifically the present invention relates to a hop extract oxidation-reaction product obtained by an oxidation-reaction of a hop extract.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: December 6, 2016
    Assignee: Kirin Holdings Kabushiki Kaisha
    Inventors: Yoshimasa Taniguchi, Yumie Kobayashi, Fumitoshi Manabe, Mikio Katayama