Patents Assigned to Kirin Holdings Kabushiki Kaisha
-
Patent number: 10568347Abstract: To provide a bottled carbonated drink including a sweetener and a caramel composition, wherein the drink contains an indigestible dextrin and the amount of 4-methylimidazole in the drink is less than 200 ppb. The drink is a bottled carbonated drink of which foam is stabilized.Type: GrantFiled: April 18, 2018Date of Patent: February 25, 2020Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, KIRIN BEVERAGE KABUSHIKI KAISHAInventors: Hiroyuki Naganuma, Kenichiro Yamamoto, Yuko Yotsumoto, Hideyuki Wakabayashi
-
Patent number: 10525088Abstract: It is an object of the present invention to provide a lactic acid bacterial immunopotentiating activity-increasing composition that increases the immunopotentiating activity of lactic acid bacteria having immunopotentiating activity; and a method for increasing the immunopotentiating activity of lactic acid bacteria using the composition; and a composition comprising both of lactic acid bacteria having an immunopotentiating activity and a lactic acid bacterial immunopotentiating activity-increasing composition, wherein the immunopotentiating activity of the lactic acid bacteria is increased. The present invention relates to a composition comprising lactic acid bacteria having an immunopotentiating activity and a lactic acid bacterial immunopotentiating activity-increasing composition comprising an ester compound of a polyol and a saturated fatty acid as an active ingredient.Type: GrantFiled: May 29, 2015Date of Patent: January 7, 2020Assignee: Kirin Holdings Kabushiki KaishaInventors: Masaya Kanayama, Kyoko Tazumi
-
Publication number: 20190374587Abstract: An object of the present invention is to provide a composition for preventing visual dysfunction caused by exposure to light, such as so-called blue light. The present invention provides a composition comprising a lactic acid bacterium as an active ingredient for use in suppressing or improving conditions caused by retinal inflammation resulting from light damage. Eye discomfort is an exemplary condition caused by retinal inflammation resulting from light damage.Type: ApplicationFiled: September 8, 2017Publication date: December 12, 2019Applicant: Kirin Holdings Kabushiki KaishaInventors: Toshihide KURIHARA, Yuji MORITA, Kenta JONAI, Daisuke FUJIWARA
-
Patent number: 10487397Abstract: An object of the present disclosure is to provide a gas barrier plastic molded body which is excellent in gas barrier properties and transparency and a method for producing the same. A gas barrier plastic molded body 90 according to the present disclosure includes a plastic molded body 91 and a gas barrier thin film 92 provided on a surface of the plastic molded body 91, and in the gas barrier plastic molded body, the gas barrier thin film 92 contains silicon (Si), carbon (C), and oxygen (O) as constituent elements and has a region, in a which a main peak is observed, at a peak appearance position of binding energy of Si—C when the gas barrier thin film is subjected to an X-ray photoelectron spectroscopic analysis under Condition (1). Condition (1): a measurement range is set to 95 to 105 eV.Type: GrantFiled: April 5, 2016Date of Patent: November 26, 2019Assignee: KIRIN HOLDINGS KABUSHIKI KAISHAInventor: Hiroyasu Tabuchi
-
Patent number: 10434133Abstract: An oligopeptide having a good anti-inflammation effect on microglia has been found, and based on this finding, a composition to be used for suppressing the inflammation of microglia is provided. Inflammation suppression action of a dipeptide has been comprehensively analyzed using the proinflammatory cytokine production of microglia as an indicator. As a result, it has been revealed that an oligopeptide including the sequence LH, DV or MH has a good inflammation suppression effect. The composition containing any of these oligopeptides can provide a composition having the effect of suppressing the excessive inflammatory action of microglia.Type: GrantFiled: May 26, 2016Date of Patent: October 8, 2019Assignee: KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Yasuhisa Ano, Masahiro Kita
-
Publication number: 20190192584Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.Type: ApplicationFiled: March 1, 2019Publication date: June 27, 2019Applicant: KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Daisuke FUJIWARA, Kenta Jonai, Tetsu Sugimura
-
Publication number: 20190128874Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: ApplicationFiled: December 13, 2018Publication date: May 2, 2019Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu TSUJI, Kumiko IKADO, Seiichi UCHIYAMA, Kyoko KAWAMOTO
-
Publication number: 20190113505Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: ApplicationFiled: December 13, 2018Publication date: April 18, 2019Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu TSUJI, Kumiko IKADO, Seiichi UCHIYAMA, Kyoko KAWAMOTO
-
Patent number: 10220060Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.Type: GrantFiled: December 2, 2016Date of Patent: March 5, 2019Assignee: Kirin Holdings Kabushiki KaishaInventors: Daisuke Fujiwara, Kenta Jonai, Tetsu Sugimura
-
Patent number: 10191035Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: GrantFiled: May 20, 2014Date of Patent: January 29, 2019Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu Tsuji, Kumiko Ikado, Seiichi Uchiyama, Kyoko Kawamoto
-
Patent number: 10138491Abstract: An object of the present invention is to provide DNA of a glycoalkaloid biosynthetic enzyme of a solanaceous plant (Solanaceae) such as a potato. The present invention relates to a protein having glycoalkaloid biosynthetic enzyme activity of a solanaceous plant such as a potato and a method for producing/detecting a novel organism using a gene encoding the protein.Type: GrantFiled: January 18, 2017Date of Patent: November 27, 2018Assignee: KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Naoyuki Umemoto, Katsunori Sasaki
-
Patent number: 10053701Abstract: Provided is DNA of biosynthetic enzyme of glycoalkaloid of solanaceous plant (Solanaceae) such as potato. Provided are a protein having activity on a biosynthetic enzyme of glycoalkaloid of solanaceous plant such as potato, and a method of creating and assaying a novel organism using a gene encoding the protein.Type: GrantFiled: November 19, 2012Date of Patent: August 21, 2018Assignee: KIRIN HOLDINGS KABUSHIKI KAISHAInventor: Naoyuki Umemoto
-
Patent number: 9765353Abstract: Provided are the DNA of a glycoalkaloid biosynthetic enzyme of solanaceous plants (Solanaceae) such as potato, solanaceous plants producing no glycoalkaloids, and a method of producing a cultivar with a reduced risk of accumulating glycoalkaloids, which involves crossing plants in which the expression of an oxidase gene involved in glycoalkaloid biosynthesis is suppressed or the activity of the enzyme is lowered, as mother plants, and screening progeny resulting from the crossing.Type: GrantFiled: March 6, 2013Date of Patent: September 19, 2017Assignee: KIRIN HOLDINGS KABUSHIKI KAISHAInventor: Naoyuki Umemoto
-
Patent number: 9737077Abstract: This invention relates to: a method for controlling the sexuality of hop, comprising applying a chemical to a hop female plant once or more and forming a fertile male flower capable of forming pollen on the female plant, wherein the chemical reduces a reaction with endogenous ethylene in the female plant; an embryo or seed, hop plant, and cone, capable of being obtained through the method; a method of screening for a hop plant; and a method of producing a hop plant variety.Type: GrantFiled: August 10, 2012Date of Patent: August 22, 2017Assignee: KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Takayuki Momma, Naoyuki Umemoto
-
Patent number: 9688995Abstract: This invention provides a plant belonging to the family Solanaceae that does not produce cholesterols, including glycoalkaloids. This invention concerns a protein having activity of an enzyme that reduces position 24 of the steroid skeleton of a plant belonging to the family Solanaceae, a novel plant in which a gene encoding such protein is suppressed, and a method for producing and testing such plant.Type: GrantFiled: March 22, 2013Date of Patent: June 27, 2017Assignee: KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Naoyuki Umemoto, Masako Otsuka
-
Publication number: 20170121727Abstract: An object of the present invention is to provide DNA of a glycoalkaloid biosynthetic enzyme of a solanaceous plant (Solanaceae) such as a potato. The present invention relates to a protein having glycoalkaloid biosynthetic enzyme activity of a solanaceous plant such as a potato and a method for producing/detecting a novel organism using a gene encoding the protein.Type: ApplicationFiled: January 18, 2017Publication date: May 4, 2017Applicant: KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Naoyuki UMEMOTO, Katsunori SASAKI
-
Publication number: 20170106028Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.Type: ApplicationFiled: December 2, 2016Publication date: April 20, 2017Applicant: KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Daisuke FUJIWARA, Kenta JONAI, Tetsu SUGIMURA
-
Publication number: 20170037345Abstract: The present invention relates to a hop extract having a reduced bitter taste which shows a fat absorption suppressing effect. More specifically the present invention relates to a hop extract oxidation-reaction product obtained by an oxidation-reaction of a hop extract.Type: ApplicationFiled: October 24, 2016Publication date: February 9, 2017Applicant: Kirin Holdings Kabushiki KaishaInventors: Yoshimasa TANIGUCHI, Yumie KOBAYASHI, Fumitoshi MANABE, Mikio KATAYAMA
-
Patent number: 9549956Abstract: This invention provides an IFN inducer comprising, as an active ingredient, lactic acid bacteria and capable of inducing IFN production, an immunopotentiating agent or prophylactic agent against virus infection comprising such inducer, and a food or drink product comprising such IFN inducer and having IFN-inducing activity, immunopotentiating activity, or prophylactic activity against virus infection. The agent for inducing IFN production comprises, as active ingredients, lactic acid bacteria that can activate plasmacytoid dendritic cells (pDCs) and promote IFN production, such as Lactococcus garvieae NBRC100934, Lactococcus lactis subsp. cremoris JCM16167, Lactococcus lactis subsp. cremoris NBRC100676, Lactococcus lactis subsp. hordniae JCM1180, Lactococcus lactis subsp. hordniae JCM11040, Lactococcus lactis subsp. lactis NBRC12007, Lactococcus lactis subsp. lactis NRIC1150, Lactococcus lactis subsp. lactis JCM5805, Lactococcus lactis subsp.Type: GrantFiled: April 28, 2014Date of Patent: January 24, 2017Assignee: Kirin Holdings Kabushiki KaishaInventors: Daisuke Fujiwara, Kenta Jonai, Tetsu Sugimura
-
Patent number: 9512389Abstract: The present invention relates to a hop extract having a reduced bitter taste which shows a fat absorption suppressing effect. More specifically the present invention relates to a hop extract oxidation-reaction product obtained by an oxidation-reaction of a hop extract.Type: GrantFiled: December 15, 2011Date of Patent: December 6, 2016Assignee: Kirin Holdings Kabushiki KaishaInventors: Yoshimasa Taniguchi, Yumie Kobayashi, Fumitoshi Manabe, Mikio Katayama