Abstract: A matrix array ultrasound probe passively dissipates heat developed by the matrix array transducer and beamformer ASIC away from the distal end of the probe. The heat developed in the transducer stack is coupled to a metallic frame inside the handle of probe. A metallic heatspreader is thermally coupled to the probe frame to convey heat away from the frame. The heatspreader surrounds the inside of the probe handle and has an outer surface which is thermally coupled to the inner surface of the probe housing. Heat is thereby coupled evenly from the heatspreader into the housing without the development of hotspots in the housing which could be uncomfortable to the hand of the sonographer.

Abstract: A movable stage system is configured to support an object subjected to a lithography process. A short stroke part (SS) is configured to support the object (W) and a long stroke part (LS) is configured to support the short stroke part. The short stroke part is movable over a relative small range of movement with respect to the long stroke part. The long stroke part is movable over a relative large range of movement with respect to a base support arranged to support the long stroke part. A shielding element (SE) is arranged between the short and long stroke parts. A position control system (PCS) maintains a substantially constant distance between the shielding element and the short stroke part.

Abstract: An instrument system that includes an image capture device, an elongate body, an optical fiber and a controller is provided. The elongate body is operatively coupled to the image capture device. The optical fiber is operatively coupled to the elongate body and has a strain sensor provided on the optical fiber. The controller is operatively coupled to the optical fiber and adapted to receive a signal from the strain sensor and to determine a position or orientation of the image capture device based on the signal.

Abstract: The present invention relates to a method for measuring Troponin I in a sample comprising the steps of providing a sample, contacting the sample with a monoclonal anti-Troponin I antibody coupled to a magnetic label, contacting the sample with a polyclonal anti-Troponin I antibody coupled to a sensor surface and detecting the magnetic label on the sensor surface. The invention further relates to a device and a cartridge for measuring Troponin I in a sample.

Abstract: An ultrasonic diagnostic imaging system produces audio Doppler from detected Doppler signals. The Doppler signals are detected in a band of frequencies which corresponds to the velocity of blood flow signals, and Doppler information is displayed based on the detected band of frequencies. The audio Doppler system produces Doppler audio in a frequency band which is shifted in pitch from the detected band of frequencies. The operator of the ultrasound system is provided with a user control by which the degree of pitch shifting can be controlled. The ultrasound system displays Doppler blood flow velocities referenced to a transmit Doppler frequency f0, with the audio Doppler being shifted in pitch from the frequencies corresponding to the blood flow velocities.

Abstract: A virtual coil emulation method is used in a magnetic resonance imaging scan for acquiring a magnetic resonance image of an object (10). The scan is performed by an MR system (1) using a physical coil arrangement (9; 11; 12; 13) including a set of individual transmit coils. The coils are adapted for transmission of a desired RF transmit field to the object (10) for magnetic resonance spin excitation of the object (10). Each coil is associated with a physical transmit channel. The RF transmit field corresponds to a virtual arrangement of two or more of the coils. Virtual transmit channel properties include virtual transmit channel weights are assigned to the RF transmit field which describe the virtual complex RF field amplitudes with respect to each individual coil of the virtual coil arrangement to be applied to the physical coils (9; 11; 12; 13) for generating the RF transmit field.

Abstract: Coil elements (18) generate a B1 excitation field in an examination region (14), which B1 excitation field is distorted by patient loading (e.g., wavelength effects). Passive shimming elements (22, 24) are disposed between the coil elements and the subject in order to improve the B1 field uniformity. In one embodiment, passive shimming elements include one or more dielectric rods (55) disposed below the subject which generate no substantial MR proton signal and which have a permittivity of at least 100 and preferably greater than 500. In another embodiment, tubes (24) adjacent each coil element are supplied with a dielectric liquid, a thickness of the dielectric liquid between the coil element and the subject adjusting a phase of the B1 field generated by the coil element. Active B1 shimming may be combined with passive shimming elements (22, 24) to effect an improved RF field homogeneity result.

Abstract: An apparatus, method and computer program for measuring a distance using a self-mixing interference (SMI) unit that generates an SMI signal. The SMI unit comprises a laser emitting a first laser beam directed to an object and wherein the SMI signal depends on an interference of the first laser beam and a second laser beam reflected by the object. A peak width determination unit determines a peak width of the SMI signal, and a distance determination unit determines a distance between the object and the SMI unit depending on the determined peak width of the SMI signal. Since the distance is determined depending on the peak width of the SMI signal, without requiring a laser driving current modulation, advanced electronics for modulating the driving current of the laser are not needed. This reduces the technical efforts needed for determining the distance.

Abstract: We provide a radiotherapeutic apparatus comprising a patient support, magnetic coils disposed around the patient support for creating a magnetic field therewithin, a radiation source producing a beam of radiation directed toward the patient support and mounted on a rotatable support thereby to rotate the radiation source around the patient support, a slip ring for conveying electrical power to the radiation source and located around the patient support, including at least one electrical interruption therein. This creates a slip ring in which there is no continuous circumferential path, and one in which the current is therefore forced to take a route via one side or the other.

Abstract: A motion-corrected magnetic resonance imaging method comprises: sequentially acquiring a plurality of interleaved magnetic resonance radial acquisition datasets using a magnetic resonance scanner; reconstructing each magnetic resonance radial acquisition dataset into a corresponding image to generate a set of images, the reconstructing including expanding radial k-space lines of the magnetic resonance radial acquisition dataset into corresponding radial bands in k-space using a generalized auto-calibrating partially parallel acquisition (GRAPPA) operator; selecting a reference image from the set of images; performing three-dimensional spatial registration of each image of the set of images except the reference image with respect to the reference image to generate a spatially registered set of images; and combining the spatially registered set of images to generate a motion corrected image.

Abstract: A radiation therapy system comprises: a radiation therapy subsystem (20, 22, 32) configured to perform radiation therapy by applying radiation pulses to a region of a subject at pulse intervals (Tpi); a magnetic resonance (MR) imaging subsystem (10, 16, 30, 36) configured to acquire a dataset of MR imaging data samples from the region of the subject over one or more MR sampling intervals (TAQ) that are longer than the pulse intervals, the one or more MR sampling intervals overlapping at least some of the pulse intervals; a synchronizer (40) configured to identify MR imaging data samples of the dataset whose acquisition times overlap pulse intervals; and a reconstruction processor (44) configured to reconstruct the dataset without the measured values for the MR imaging data samples identified as having acquisition times overlapping pulse intervals to generate a reconstructed MR image.

Abstract: The present invention relates to a device (8) for determining tissue layer boundaries of a body (14), comprising a probe (10) for acquiring (S12) two or more ultrasound images (36) at adjacent positions of a surface (12) of the body (14), a converter (44) for converting (S14) said ultrasound images (36) separately to depth signals (46), wherein a depth signal (46) is obtained by summing intensities of one of said ultrasound images (36) along a line (66) of substantially constant depth in the body (14), a detector (48) for detecting (S16) a set of candidate tissue layer boundaries (50) for an ultrasound image (36) by thresholding the depth signal (46) obtained for said ultrasound image (36), a selection means (52) for selecting (S18) from a set of candidate tissue layer boundaries (50) a nearest candidate tissue layer boundary (54) that is nearest to the surface (12) of the body (14), and a processing means (56) for determining (S20) an actual tissue layer boundary (58) from the nearest candidate tissue layer

Abstract: The invention relates to a method of characterizing the RF transmit chain of a magnetic resonance imaging scanner (1) using a local transmit/receive coil system (204; 210), comprising a first local NMR probe and a first local magnetic resonance coil, the first NMR probe being spatially located in immediate neighborhood to the first coil, a local receive coil system (206; 208), comprising a second local NMR probe and a second local magnetic resonance coil, the second NMR probe being spatially located in immediate neighborhood to the second coil, wherein the transmit chain comprises an external MR coil (9; 11; 12; 13), the method comprising: determining with the first magnetic resonance coil, a first MR signal phase evolution of the local RF transmit field generated by MR excitation of the first probe using the first magnetic resonance coil by measuring the RF response of the first probe upon said excitation, determining with the second magnetic resonance coil a second MR signal phase evolution of the local RF

Abstract: At least a portion of a body (10) of a patient positioned in an examination volume of a MR device (1). A portion of the body (10) is subject to a calibration sequence including RF pulses and switched magnetic field gradients controlled in such a manner that a calibration signal data set is acquired by a multi-point Dixon technique at a first image resolution. Calibration parameters are derived from the calibration signal data set. The MR device (1) is controlled according to the derived calibration parameters. The portion of the body (10) is subject to an imaging sequence including RF pulses and switched magnetic field gradients controlled in such a manner that a diagnostic signal data set is acquired at a second image resolution which is higher than the first image resolution. A diagnostic MR image is reconstructed from the diagnostic signal data set.

Abstract: At least a portion of a body (10) of a patient is positioned in an examination volume of a MR device (1). The portion of the body (10) is subject to a calibration sequence including RF pulses and switched magnetic field gradients controlled in such a manner that a calibration signal data set is acquired by a multi-point Dixon technique at a first image resolution. Calibration parameters are derived from the calibration signal data set. The portion of the body (10) is subject to an imaging sequence including RF pulses and switched magnetic field gradients controlled in such a manner that a diagnostic signal data set is acquired at a second image resolution which is higher than the first image resolution A diagnostic MR image is reconstructed from the diagnostic signal data set. The MR device (1) is operated according to the derived calibration parameters with fat saturation during acquisition of the diagnostic signal data set and/or during reconstruction of the diagnostic MR image.

Abstract: A magnetic resonance imaging scan using a MR scanner receives via a user interface a MR imaging protocol categorizable into a MR scan type of a predefined set of MR scan types. Further, a database is queried by providing to the database scan information permitting the database to identify the MR scan type of the MR imaging protocol. Statistical information on the MR scan type which can include statistics on modifications of individual scan parameters of the MR scan type is received from a database, and the statistical information is provided to the user interface. Modifications of the MR imaging protocol can be received from the user interface, resulting in a modified MR imaging protocol, according to which the MR imaging scan can be performed.

Abstract: A state space feedback controller operates in the digital domain for the regulation of the current supply to MRI gradient coils from a multiple-bridge PWM power amplifier. The P1-controller includes an integration part (for the integration of the difference between the demand current and the measured gradient coil current) and a subsequent P-controlled system which in turn includes a delay compensator/stabilizer and a plant. The delay compensator/stabilizer includes a multi-path feedback loop by means of which its digital output signal is fed back through delay blocks, on the one hand, and through filter units, on the other hand. The filter units model the transfer functions of a gradient coil output filter for the gradient coil voltage and the output current of the amplifier inverter units, respectively. In the plant, a filter unit, which models the gradient coil transfer function, is connected in series to a delay chain for the delay of the measurement value of the gradient coil current.

Abstract: The invention relates to a digital amplifier for providing a desired electrical output power, the amplifier comprising a power source (100) for generating the electrical output power, the amplifier further comprising: a digital input adapted for receiving a digital input signal (112), the digital input signal (112) representing the desired electrical output power level, a reference power generator (124) for generating an analog reference power controlled by the digital input signal (112), a power measurement component (142; 128) adapted for measuring the power differential between the electrical output power provided by the power source (100) and the analog reference power, an analog-to-digital converter (130) adapted for converting the power differential into a digital power differential value (132), a combiner adapted for providing a combined digital signal (136) by adding the digital power differential value (132) to the digital value input to the reference power generator (124) for generating the analog r

Abstract: An RF volume resonator system is disclosed comprising a multi-port RF volume resonator (40, 50; 60), like e.g. a TEM volume coil or TEM resonator, or a birdcage coil, all of those especially in the form of a local coil like a head coil, or a whole body coil, and a plurality of transmit and/or receive channels (T/RCh1, . . . T/RCh8) for operating the multi-port RF volume resonator for transmitting RF excitation signals and/or for receiving MR relaxation signals into/from an examination object or a part thereof. By the individual selection of each port (P1, . . . P8) and the appropriate amplitude and/or frequency and/or phase and/or pulse shapes of the RF transmit signals according to the physical properties of an examination object, a resonant RF mode within the examination object with an improved homogeneity can be excited by the RF resonator.

Abstract: At least two chemical species are imaged using magnetic resonance imaging with signal separation for the two chemical species. The method includes acquiring first and second echo data at different echo times resulting in a first and second acquired complex dataset, —modelling the first and second acquired dataset, said modelling comprising a spectral signal model of at least one of the chemical species, —identifying in the first and second acquired dataset the voxels for which the modelling yields a single, unambiguous mathematical solution for the signal separation, and —resolving the ambiguity for the voxels for which the modelling yields more than one mathematical solution, if any such voxels remain.