Abstract: A self-healing conjugated polymer is disclosed. The self-healing conjugated polymer has hydrogen bonding functional groups introduced into its side chains. Due to this structure, the conjugated polymer is imparted with the ability to recover through self-healing while maintaining its inherent properties (for example, physical and electrical properties). Based on this effective self-healing ability, the conjugated polymer is expected to find application as a biomaterial, a pharmaceutical material, a nonlinear optical material or an organic electronic material.

Abstract: There is provided a method and an apparatus for diagnosing an object placement error by using an artificial neural network by which feature data of the (N+1)-th stage among the feature data of a plurality of stages is generated by using any one feature data among a plurality of feature data generated in an operation process of a main network and feature data of the plurality of stages, and a placement error of at least one object is diagnosed by using an artificial neural network of a new structure, and thus, the diagnosis accuracy of a placement error of an object that is difficult to detect an edge, such as a transparent vial, may be greatly increased.

Abstract: A robot arm is provided. The robot arm according to an aspect of the present disclosure comprises a motor portion; a support connected to the motor portion; first and second links connected to the motor portion and movable in a vertical direction; a first gimbal coupled to upper ends of the first and second links, respectively; third and fourth links coupled to the first gimbal; fifth and sixth links coupled to lower ends of the third and fourth links, respectively; seventh and eighth links coupled to central areas of the fifth and sixth links in the vertical direction; a second gimbal coupled to upper ends of the seventh and eighth links; ninth and tenth links coupled to the second gimbal; eleventh and twelfth links coupled to lower ends of the ninth and tenth links; and a top portion coupled to upper ends of the fifth and sixth links and upper ends of the eleventh and twelfth links.

Abstract: A method for a breast biopsy based on indirect magnetic resonance imaging (MRI) guidance of present disclosure, may comprises obtaining a breast MRI data of a patient, generating a deformable breast model using the breast MRI data, measuring real-time breast shape of the patient using a depth sensor, performing a real-time deformable registration using the deformable breast model and the real-time shape data, estimating movements of the MRI targets inside of the breast, performing a breast biopsy for the MRI targets.

Abstract: Disclosed is a gait start intention detection device for detecting a walker's gait start intention, including a plurality of left foot sole sensor units and a plurality of right foot sole sensor units to measure ground reaction force signals generated from foot soles while walking, and a calculation unit to receive and calculate the left ground reaction force signal and the right ground reaction force signal, wherein the calculation unit calculates a center of pressure (COP) location in a walking direction and a direction perpendicular to the walking direction using data of the ground reaction force signal measured from each sensor unit, and detects the walkers gait start intention when a ground reaction force of a swing foot heel of the walker increases, and at the same time, the COP location moves to a rear side of the walker.

Abstract: Therapeutic compounds for red blood cell-mediated delivery of an active pharmaceutical ingredient to a target cell are described. The therapeutic compounds are configured to bind CD47 on the surface of a red blood cell and to be subsequently transferred to CD47 on the surface of the target cell, the therapeutic compound ultimately being internalized by the target cell via endocytosis. The target cell may be a cancer cell.

Abstract: The present invention relates to a non invasive diagnostic method of pancreatic ductal adenocarcinoma (PDAC) in a subject said method comprising the step of measuring the level of ?ig-h3 protein in a blood sample wherein the serum level of ?ig-h3 is positively correlated with the risk of having a PDAC. By following studies on 2 distinct cohorts of 20 and 104 of PDAC patients, and on PDAC mouse model, the inventors show that ?ig-h3 can be directly detected in the blood sample and ?ig-h3 is expressed very early in tumorigenesis in pancreatic neoplastic lesions. The present invention also relates to antagonist of ?ig-h3 protein, for use in the treatment of PDAC. The inventors found that ?ig-h3 bind directly on CD8+ T cells by reducing their activation and cytotoxic properties. Furthermore, the use of neutralizing ?ig-h3 antibodies in PDAC mouse model, reduced tumor growth by enhancing CD8+ T cell anti-tumoral response.

Abstract: Provided is a method of preparing a three-dimensional cell spheroid, the method including forming the cell spheroid by co-culturing adipose-derived stem cells or mesenchymal stem cells with hepatocytes. According to the cell spheroid prepared by the method, the secretome secreted by the adipose-derived stem cells affects hepatocyte maturation, and therefore, hepatic functions of the finally formed three-dimensional cell spheroid, i.e., organoid, may be enhanced. Further, a composition including a culture medium of the adipose-derived stem cells may prevent or treat liver diseases including hepatitis, hepatotoxicity, cholestasis, fatty liver, etc., and may enhance hepatic functions.

Abstract: The present invention relates to a use of a fermentation product of Lacticaseibacillus casei of cannabis stems and an extract thereof for ameliorating skin wrinkles caused by photoaging, and to an anti-wrinkle cosmetic composition or pharmaceutical composition including the fermentation product.

Abstract: The present disclosure relates to a hydrogen purification/storage apparatus and method using a liquid organic hydrogen carrier (LOHC).

Abstract: The present invention relates to a recombinant exosome containing hyaluronidase and a use thereof, and more particularly to a recombinant exosome that presents hyaluronidase on its surface and use thereof as an anticancer agent.

Abstract: A gripper for gripping a target has a first support section, a second support section spaced apart from the first support section in a direction of a rotation center axis, and a plurality of elastic wires supported across the first support section and the second support section. A first grip area surrounded by the plurality of elastic wires is formed between the first support section and the second support section upon a relative rotation of the first support section and the second support section around the rotation center axis, and the first grip area becomes narrower until all the plurality of elastic wires come into contact with the target by the relative rotation of the first support section and the second support section, and the plurality of elastic wires is tightened to grip the target entering the first grip area.

Abstract: Disclosed embodiments are directed to providing an apparatus and method for summarizing information using a generative artificial intelligence model that is capable of generating an answer sentence and an image summarizing and organizing numerous information associated with a user's search term using a pre-trained generative artificial intelligence model, and generating and providing answer content that includes the generated sentence and image.

Abstract: Disclosed is a composition for preventing or treating a degenerative brain disease. The composition includes, as an active ingredient, a MECP2 inhibitor for treating the degenerative brain disease, a polynucleotide encoding the MECP2 inhibitor or a recombinant virus containing the MECP2 inhibitor. The composition is useful for the treatment of a degenerative brain disease (particularly Alzheimer's syndrome) caused by beta-amyloid. In addition, the composition is effective in improving or ameliorating deterioration of cognitive functions and social deficits caused by Alzheimer's syndrome.

Abstract: Disclosed is a method for simultaneous analysis of neurotransmitters and/or their metabolites. The method includes (a) separating analytes including a plurality of neurotransmitters and/or their metabolites from a sample selected from body tissues, body fluids, secretions, and excretions, (b) derivatizing the analytes with ethyl chloroformate to obtain derivatives of the plurality of neurotransmitters and/or their metabolites, (c) separating the derivatives of the plurality of neurotransmitters and/or their metabolites by liquid chromatography, and (d) subjecting the separated derivatives of the neurotransmitters or their metabolites to multiple reaction monitoring (MRM) using a mass spectrometer. According to the method, a plurality of neurotransmitters in a very small amount of sample can be simultaneously analyzed in an accurate and rapid manner based on derivatization to increase the stability and ionization efficiency of the substances.

Abstract: The present disclosure relates to a magnetic field-based jamming mechanism with variable stiffness and shape adaptation functionalities that can adapt to various characteristics (shape, softness, etc.) of the external environment, and can easily grip objects having various shapes since it grips objects using changes in the stiffness of soft magnetic particles.

Abstract: A nano spintronic device for using the spin current of a ferromagnetic material and the spin current of a heavy metal channel. The device includes a lower channel layer, a free layer, a pinned layer, an insulating film layer, and an upper channel layer. When current flows upon application of power, electrons are divided into +y-polarized spins and ?y-polarized spins in the lower channel layer, thereby generating torque in the free layer. The torque switches the magnetization direction of the free layer to an +y-axis direction or an ?y-axis direction so that the free layer stores magnetization information according to the magnetization direction. When current flows in the upper channel layer, the current flows into the pinned layer so that electrons in the pinned layer are divided into +y-polarized spins and ?y-polarized spins. The insulating layer insulates the free layer and the pinned layer from each other.

Abstract: The present disclosure relates to a method of deriving quality improvement requirements. The method according to some embodiments may include receiving a plurality of evaluation information for a first product from an evaluation information database, inputting the plurality of evaluation information into a key phrase extraction model and determining key phrases for the plurality of evaluation information based on an output of the key phrase extraction model, grouping some of the key phrases for the plurality of evaluation information into multiple groups and storing information on each of the multiple groups in a memory, ranking the key phrases included in each of the multiple groups and storing information associated with the ranks of the key phrases included in each of the multiple groups in the memory and determining top n key phrases from each of the multiple groups as quality improvement requirements.

Abstract: A forceps unit and a forceps apparatus are provided. The forceps unit according to an aspect of the present disclosure may comprise a base portion connected to a motor; a grasping portion disposed in front of the base portion and grasping a surgical instrument; a connecting portion connecting the base portion and the grasping portion; and a plurality of optical fibers, wherein some of the plurality of optical fibers are fixed to the grasping portion and others of the plurality of optical fibers are fixed to the base portion, wherein the plurality of optical fibers may include a first optical fiber disposed in a central region of the grasping portion and second to fifth optical fibers radially disposed with respect to the first optical fiber, and the first optical fiber may protrude further forward than the second to fifth optical fibers.

Abstract: The present invention relates to a composition for preventing or treating liver fibrosis, which includes a Sanguisorba officinalis extract as an active ingredient, and more particularly, to a composition for preventing or treating liver fibrosis, which includes a Sanguisorba officinalis extract or ziyuglycoside. The Sanguisorba officinalis extract or ziyuglycoside of the present invention inhibits liver fibrosis and the expression of a liver fibrosis-related gene, so it may be effectively used in the composition for preventing or treating liver fibrosis.