Patents Assigned to Korea Research Institute of Chemical Technology
  • Self-restoring polyurethane-based polymer and preparation method therefor
    Patent number: 11299578
    Abstract: A self-restoring polyurethane-based polymer obtained by polymerization of a composition containing an aromatic disulfide diol represented by Chemical Formula, HO—Ar1—S—S—Ar2—OH, an alicyclic polyisocyanate, and a polyol. Ar1 and Ar2 each are independently a substituted or unsubstituted C6-C30 arylene group. The composition satisfies Equation, 0.1?M[disulfide]/M[OH]. M[disulfide] is a total mole number of the aromatic disulfide diol in the composition, and M[OH] is a total mole number of the aromatic disulfide diol and the polyol in the composition.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: April 12, 2022
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Sung Yeon Hwang, Jeyoung Park, Dong Yeop Oh, Jong Geon Jegal, Seon Mi Kim, Hyeon Yeol Jeon
  • Organic-inorganic hybrid nanoporous material containing intramolecular acid anhydride functional group, composition for adsorption comprising the same, and use thereof for separation of hydrocarbon gas mixture
    Patent number: 11285455
    Abstract: The present invention relates to an organic-inorganic hybrid nanoporous material, maintaining a nanoporous skeleton structure formed by coordination of an organic ligand containing an aromatic compound to a trivalent central metal ion, and further having an intramolecular acid anhydride functional group modified on the aromatic compound of the nanoporous skeleton structure, and thereby exhibits selectivity for olefins, and an adsorbent comprising the same. Specifically, the organic-inorganic hybrid nanoporous material of the present invention exhibits an excellent olefin-selective adsorption capacity through differences in adsorption equilibrium and adsorption rate, and thus can be usefully employed in the separation of C2-C4 hydrocarbons.
    Type: Grant
    Filed: October 17, 2017
    Date of Patent: March 29, 2022
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Ji Woong Yoon, Jong San Chang, Young Kyu Hwang, Kyung Ho Cho, U Hwang Lee, Su Kyung Lee, Ji Sun Lee
  • Catalyst regenerator
    Patent number: 11279885
    Abstract: A catalyst regenerator according to an embodiment of the present invention, as a catalyst regenerator that regenerates a coked catalyst separated from a product produced in an endothermic catalytic reaction of a fluidized bed reactor, includes: a reaction chamber that includes a regeneration space, receives the coked catalyst from a standpipe connected to the regeneration space, and discharges a regenerated catalyst to an outlet; a fuel supplier that is connected to the reaction chamber to inject a fuel for combustion into the regeneration space; and a fuel supplier that is connected to the reaction chamber to inject an air for combustion into the regeneration space, wherein the fuel injected from the fuel supplier is a reformed fuel containing hydrogen and carbon monoxide.
    Type: Grant
    Filed: May 10, 2019
    Date of Patent: March 22, 2022
    Assignees: KOREA INSTITUTE OF MACHINERY & MATERIALS, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Sungkwon Jo, Seongil Choi, Donghyun Cho, Dae-hoon Lee, Kwan-Tae Kim, Younghoon Song, Yong-Ki Park, Na Young Kang
  • Stereotactic device for primate brains
    Patent number: 11273000
    Abstract: A stereotactic device for primate brains indicates a brain coordinate reference point of a primate using a simulator for indicating a brain coordinate reference point, thereby providing an initial setting to a zero point corresponding to the brain coordinate reference point. The brain coordinate reference point is conveniently and accurately indicated without relatively expensive equipment, such as a magnetic resonance imaging (MRI) scanner, to determine brain coordinates of the primate, so that a targeting procedure can be conducted on the brain.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: March 15, 2022
    Assignees: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Hyung Sun Kim, Su Cheol Han, Dong Ho Woo, Young Su Yang, Goo Hwa Kang, Hyung Ihl Kim, Ji Young Park, Dong Hak Byun
  • SYSTEM AND METHOD FOR RECOVERING CARBON MONOXIDE CONTAINED IN INDUSTRIAL BY-PRODUCT GAS
    Publication number: 20220062815
    Abstract: Disclosed herein is a system for recovering carbon monoxide from an industrial by-product gas, the system including a supply unit for supplying an industrial by-product gas containing carbon dioxide, nitrogen, carbon monoxide, and hydrogen, a first membrane separation unit including a separation membrane capable of allowing carbon dioxide and hydrogen to permeate, and receiving the industrial by-product gas supplied from the supply unit to allow carbon dioxide and hydrogen to permeate, and a second membrane separation unit including a polymer membrane in which a transition metal is supported, and receiving a gas remaining in the first membrane separation unit to allow carbon monoxide to permeate.
    Type: Application
    Filed: August 30, 2021
    Publication date: March 3, 2022
    Applicant: Korea Research Institute of Chemical Technology
    Inventors: Jeong Hoon Kim, Jong Yeol Jeon, Bo Ryoung Park, Ho Cheol Kang
  • N2,N4-diphenylpyrimidine-2,4-diamine derivative, method for preparing same, and pharmaceutical composition containing same as active ingredient for prevention or treatment of cancer
    Patent number: 11253516
    Abstract: The present invention relates to a N2,N4-diphenylpyrimidin-2,4-diamine derivative, a method for preparing the same, and a pharmaceutical composition for the prevention or treatment of cancer, containing the same as an active ingredient. The derivative shows a relatively weak EGFR activity inhibitory effect on wild-type EGFR, a high inhibitory ability on EGFR mutation, and a high inhibitory ability on even FLT3 and FLT3 mutation, and thus, can be effectively used for the treatment of cancer with EGFR mutation or cancer with FLT3 or a mutation thereof, and the derivative shows a synergy effect at the time of combination administration, and thus can be effectively used for the treatment of combination administration.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: February 22, 2022
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Kwangho Lee, Inji Shin, Gildon Choi, Chong Hak Chae, Hyeon Jeong Choe, Myoung Eun Jung, Byeong Uk Jeon, Byoung Chul Cho, Chae Won Park, Hwan Kim, Krishna Babu Duggirala
  • PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING PLK1 INHIBITOR AS ACTIVE INGREDIENT
    Publication number: 20220033405
    Abstract: The present invention relates to a pharmaceutical composition for preventing, treating or alleviating cancer, containing a PLK1 inhibitor as an active ingredient, and a compound according to the present invention selectively binds to PBD of PLK1, thereby having advantages of high selectivity and binding affinity for PLK1 and low toxicity. Therefore, a PLK inhibitor compound according to the present invention can be effectively used as an anticancer agent by inhibiting the growth of various cancer cells, and can be expected to exhibit synergistic effects with existing developed anticancer agents through co-administration, in addition to individual administration thereof.
    Type: Application
    Filed: November 29, 2018
    Publication date: February 3, 2022
    Applicants: NATIONAL CANCER CENTER, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Kyungtae KIM, Byung Il LEE, Joong-Won PARK, Eun Sook LEE, Sang Jin LEE, Seoung Min BONG, Jin Sook KIM, Minji PARK, Eun-Kyung YOON, Joo-Youn LEE, Su-Hyung LEE
  • Adsorbents comprising organic-inorganic hybrid nanoporous materials for sorption of water or alcohol and use thereof
    Patent number: 11224856
    Abstract: Provided are a water and/or alcohol adsorbent including organic-inorganic hybrid nanoporous materials, and use thereof, and more particularly, a water and/or alcohol adsorbent having a high adsorption amount at a low relative humidity or partial pressure, of which desorption/regeneration is possible at a low temperature, the water and/or alcohol adsorbent including organic-inorganic hybrid nanoporous materials having 0.5 to 3 mol of a hydroxyl group (OH) or a hydroxide anion group (OH?) per 1 mol of a central metal ion, and use thereof.
    Type: Grant
    Filed: May 18, 2016
    Date of Patent: January 18, 2022
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Jong San Chang, U Hwang Lee, Young Kyu Hwang, Christian Serre, Thomas Devic, Amandine Cadiau, Norbert Stock, Nele Reimer, Michael T. Wharmby
  • NOVEL TRICYCLIC COMPOUND AS IRAK4 INHIBITOR
    Publication number: 20220009933
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating autoimmune diseases or tumors, containing, as an active ingredient, a tricyclic compound represented by the following Chemical Formula 1 or a pharmaceutically acceptable salt thereof, and a health food composition for preventing or alleviating autoimmune diseases or tumors, containing the tricyclic compound as an active ingredient, wherein the tricyclic compound represented by Chemical Formula 1 has an excellent inhibitory activity against IRAK4, and thus can be usefully used for the prevention, treatment, or alleviation of autoimmune diseases or tumors.
    Type: Application
    Filed: November 20, 2019
    Publication date: January 13, 2022
    Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Heeyeong Cho, Hee-Jong Lim, Woo Kyu Park, Dae Young Jeong, Hyeon Young Kim, Sae-Bom Yoon, Chong Ock Lee, Heung Kyoung Lee, Victor Sukbong HONG, Ji Hye Choi
  • Activated Carbon Catalyst for Hydrogen Peroxide Decomposition, Method for Producing Same, and Method for Decomposing Hydrogen Peroxide by Using Same
    Publication number: 20210402375
    Abstract: Disclosed herein are an activated carbon catalyst for hydrogen peroxide decomposition, a preparation method thereof and a hydrogen peroxide decomposition method using the same. The activated carbon catalyst for hydrogen peroxide decomposition, provided in an aspect of the present invention may be easily prepared through the carbonization and activation of an ion exchange resin, and safer and higher decomposition efficiency of hydrogen peroxide may be achieved than the conventional catalyst for hydrogen peroxide decomposition through the control of the manganese content and pore properties in the catalyst.
    Type: Application
    Filed: October 31, 2019
    Publication date: December 30, 2021
    Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Jeong Kwon SUH, Ji Sook HONG, Iljeong HEO
  • METHOD FOR FABRICATION OF THREE-DIMENSIONAL LUNG ORGANOID COMPRISING HUMAN STEM CELL-DERIVED ALVEOLAR MACROPHAGE
    Publication number: 20210395695
    Abstract: The present invention relates to a method for fabrication of a three-dimensional lung organoid comprising human stem cell-derived alveolar macrophages. Specifically, a lung organoid is fabricated by co-culturing cells not expressing the definitive endoderm marker CRCX4 according to a fabrication method of the present disclosure. The lung organoid comprises type 1 and type 2 alveolar epithelial cells as well as alveolar macrophages and realizes infectious or inflammatory responses unlike conventional lung organoids that contain no immune cells and as such, can be advantageously used in studying mechanisms of related lung diseases, excavating biomarkers, developing therapeutic agents, and so on.
    Type: Application
    Filed: December 20, 2019
    Publication date: December 23, 2021
    Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Eun-Mi Kim, Ki-Suk Kim, Hyang-Ae Lee
  • Piperidine-2,6-dione derivative and use thereof
    Patent number: 11192878
    Abstract: The present disclosure relates to a novel piperidine-2,6-dione derivative and a use thereof and, more specifically, to a piperidine-2,6-dione derivative compound having a structure of a thalidomide analog. A compound of chemical formula 1 according to the present disclosure specifically binds with CRBN protein, and is involved in functions thereof. Therefore, the compound of the present disclosure can be favorably used in the prevention or treatment of leprosy, chronic graft versus host disease, an inflammatory disease, or cancer, which are caused by actions of CRBN protein.
    Type: Grant
    Filed: May 11, 2018
    Date of Patent: December 7, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Jong Yeon Hwang, Jae Du Ha, Sung Yun Cho, Pil Ho Kim, Chang Soo Yun, Chi Hoon Park, Chong Ock Lee, Sang Un Choi, Joo Youn Lee, Sunjoo Ahn
  • Increased production of ginsenosides through yeast cell organelle improvement
    Patent number: 11186616
    Abstract: Provided are a recombinant yeast having improved ability to produce ginsenoside, which is prepared by overexpressing INO2 and INO4 or deleting OPT1 in a yeast having ability to produce ginsenoside, a method of preparing the yeast, and a method of producing ginsenoside by using the yeast.
    Type: Grant
    Filed: September 21, 2020
    Date of Patent: November 30, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Ju Young Lee, In Seung Jang, Seohyun Kim, Sun-Chang Kim, Suk Chea Jung, Jong Geon Jegal
  • Method for preparing sulfated metal oxide catalyst for chlorination, and chlorination method using sulfated metal oxide catalyst
    Patent number: 11179712
    Abstract: The present invention relates to a method for preparing a sulfated metal oxide catalyst for chlorination, and a method for producing a reaction product containing methyl chloride (CH3Cl) by using the sulfated metal oxide catalyst. A sulfated zirconia catalyst and a sulfated tin oxide catalyst are disclosed as the sulfated metal oxide catalyst for chlorination.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: November 23, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Ho Jeong Chae, Young Min Kim, Jip Kim, Hyung Ju Kim
  • CATALYST FOR PRODUCING OLEFIN, INCLUDING OXYGEN CARRIER MATERIAL AND DEHYDROGENATION CATALYST
    Publication number: 20210354113
    Abstract: Disclosed is a catalyst for producing an olefin including an oxygen carrier material and a dehydrogenation catalyst. The catalyst allows hydrogen to be converted into water by using oxygen inside the lattice of an oxide catalyst without the additional supply of oxygen, and thus, the conversion can be increased while the decrease in selectivity, which is a disadvantage of an additional oxidative dehydrogenation reaction (ODHP), is suppressed.
    Type: Application
    Filed: May 14, 2019
    Publication date: November 18, 2021
    Applicants: SK GAS CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Yong Ki PARK, Won Choon CHOI, Daesung PARK, Hawon PARK, Changyeol SONG, Deuk Soo PARK, Ung Gi HONG, Miyoung LEE
  • METHOD OF PRODUCING OLEFIN USING CIRCULATING FLUIDIZED BED PROCESS
    Publication number: 20210354112
    Abstract: Disclosed is a method of producing an olefin using a circulating fluidized bed process, including: (a) supplying a hydrocarbon mixture including propane and a dehydrogenation catalyst to a riser which is in a state of a fast fluidization regime, and thus inducing a dehydrogenation reaction; (b) separating an effluent from the dehydrogenation reaction into the catalyst and a propylene mixture; (c) stripping, in which a residual hydrocarbon compound is removed from the catalyst separated in step (b); (d) mixing the catalyst stripped in step (c) with a gas containing oxygen and thus continuously regenerating the catalyst; (e) circulating the catalyst regenerated in step (d) to step (a) and thus resupplying the catalyst to the riser; and (f) cooling, compressing, and separating the propylene mixture, which is a reaction product separated in step (b), and thus producing a propylene product.
    Type: Application
    Filed: December 4, 2019
    Publication date: November 18, 2021
    Applicants: SK GAS CO., LTD., KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, KOREA NATIONAL UNIVERSITY OF TRANSPORTATION INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Yong Ki PARK, Won Choon CHOI, Daesung PARK, Hawon PARK, Changyeol SONG, Deuk Soo PARK, Ung Gi HONG, Miyoung LEE, Sungwon KIM, Chaeeun YEO
  • Perovskite solar cell
    Patent number: 11177403
    Abstract: A perovskite solar cell adopts a compound having a specific central backbone having a carbazolylamino group as a substituent, and more particularly, to the perovskite solar cell adopts a compound, as a hole transport material, having a specific central backbone having a carbazolylamino group as a substituent, and a spirobifluorene compound having a carbazolylphenylamino group. The perovskite solar cell has very excellent high-temperature stability while having a high power generation efficiency.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: November 16, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Jaemin Lee, Hye Jin Na, Nam Joong Jeon, Tae Youl Yang, Jang Won Seo
  • Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient
    Patent number: 11166891
    Abstract: The present invention relates to a bis phenyl hexa triene derivative, a preparation method thereof and a composition for skin whitening comprising the same as an active ingredient. The said derivative inhibits the expression of tyrosinase, TRP 1 (tyrosinase-related protein 1), TRP 2 (tyrosinase-related protein 2) or MITF (microphthalmia-associated transcription factor) gene which produces a precursor necessary for the generation of melanin, suppresses the activity of tyrosinase, eventually inhibits the biosynthesis of melanin, is safe due to low cytotoxicity, and has less side effects and excellent antioxidative effect, so that it can be effectively used as a composition for skin whitening.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: November 9, 2021
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Woo-Keun Kim, Sangwoo Lee, Seokjoo Yoon, Chul Min Park
  • Botulinum Toxin Pharmaceutical Composition Comprising Tannic Acid
    Publication number: 20210338784
    Abstract: The present invention relates to a botulinum toxin pharmaceutical composition comprising tannic acid as an active ingredient. The botulinum toxin pharmaceutical composition comprising tannic acid provided in one aspect of the present invention improves the activity of the botulinum neurotoxin itself, allows the botulinum neurotoxin to stay in the injected place, and prevents the botulinum neurotoxin from spreading to the blood due to the properties of tannic acid. Therefore, the composition of the present invention has an effect of minimizing the side effects of the conventional Botox caused by the spread of the botulinum neurotoxin.
    Type: Application
    Filed: October 27, 2020
    Publication date: November 4, 2021
    Applicant: Korea Research Institute of Chemical Technology
    Inventors: Sun-Hyun PARK, Ki-Suk KIM, Jae-Meun LEE, Jae-Hyeok LEE
  • ISOINDOLIN-1-ON DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER
    Publication number: 20210332029
    Abstract: The present invention relates to an isoindolin-1-on derivative, a method for preparing same, and a pharmaceutical composition comprising same as an effective component for preventing or treating tumors, wherein the isoindolin-1-on derivative exhibits a high inhibitory effect on EGFR mutations, and thus can be beneficially used for the treatment of EGFR-mutated tumors, and the isoindolin-1-on derivative exhibits a significant synergistic effect when co-administered, and thus can be beneficially used in concomitant therapy.
    Type: Application
    Filed: August 12, 2019
    Publication date: October 28, 2021
    Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Kwangho Lee, Gildon Choi, Seoyoung Lee, Jiwon Kim, Byoung Chul Cho, Chae Won Park, Jiyeon Yun