Patents Assigned to Korea Research Institute
  • Patent number: 11796406
    Abstract: An apparatus and method for detecting composite material damage due to impact by using distributed optical fiber are disclosed. In the apparatus and method for detecting composite material damage due to impact by using distributed optical fiber, the position and level of damage occurring in a composite material due to low-velocity impact can be effectively and economically detected by measuring the residual strain of optical fiber distributed on the surface of the composite material or inside the composite material. In the apparatus and method for detecting composite material damage due to impact by using distributed optical fiber, there is no need to always operate a sensor in real time, so that detection errors due to temporary failures, malfunctions, etc. of the sensor, as well as a problem of constantly supplying power to the sensor, can be essentially removed.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: October 24, 2023
    Assignee: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: Il-Bum Kwon, Dae-Cheol Seo, Chi Yup Kim
  • Publication number: 20230333109
    Abstract: The present invention relates to a composition for diagnosing infectious diseases, comprising an agent for measuring the expression level of sterol regulatory element-binding protein 2 (SREBP2) and, more specifically, to a composition for diagnosing infectious diseases or diagnosing the severity thereof, the composition comprising an agent for measuring the expression level of sterol regulatory element-binding protein 2 (SREBP2) or a C-terminal peptide thereof.
    Type: Application
    Filed: August 20, 2021
    Publication date: October 19, 2023
    Applicants: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY, KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Young Kyo SEO, Jong Sup BAE, Wonhwa LEE, Youngbum YOO
  • Publication number: 20230331552
    Abstract: There is provided a method for producing trifluoroamine oxide. The method includes a step of preparing an intermediate product by simultaneously providing and reacting nitrogen trifluoride and nitrous oxide under the presence of a SbF5 reaction catalyst; and a step of producing trifluoroamine oxide by reacting the intermediate product with potassium fluoride. The step of reacting the intermediate product with potassium fluoride is performed under atmospheric pressure and room temperature.
    Type: Application
    Filed: September 23, 2021
    Publication date: October 19, 2023
    Applicants: SK SPECIALTY CO., LTD, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Junghun KWAK, Byunghyang KWON, Yongjun CHO, Injoon PARK, Shinhong YUK, Bongjun CHANG, Hongsuk KANG, Eunho SOHN, Sanggoo LEE, Jihoon BAIK, Juhyeon KIM, Myoungsook LEE, Wonwook SO
  • Patent number: 11782010
    Abstract: The present invention relates to an electrode for a biosensor for NADH measurement and a manufacturing method therefor. An electrode manufactured by the method according to the present invention enjoys the advantages of stabilizing current flow during an electric polymerization reaction, making the contact angle of the modified material remarkably small to increase the efficiency of surface modification, and being reusable several times. In addition, when applied to a biosensor for NADH measurement, the electrode of the present invention maintains sensitivity and selectivity at a high level without interference and thus easily measures a target of interest even in blood or serum that necessarily requires a pretreatment process due to the existence of a trace amount of a material to be measured.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: October 10, 2023
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventor: Kyuhong Lee
  • Publication number: 20230305028
    Abstract: The present disclosure provides a reagent composition for detecting illicit drugs, the composition comprising: a diacetylene derivative compound represented by chemical formula 1; and at least one compound selected from among gabazine (SR-95531), an amine group-linked diacetylene derivative represented by chemical formula 2-1, and a gabazine-linked diacetylene derivative represented by chemical formula 2-2.
    Type: Application
    Filed: May 14, 2021
    Publication date: September 28, 2023
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Eun Kyung LIM, Soo Jin JANG, Seong Uk SON, Byung Hoon KANG, Tae Joon KANG, Kyu Sun LEE, Ju Yeon JUNG
  • Publication number: 20230304989
    Abstract: The disclosure relates to nanopore-based technology for screening of drugs against target RNA. According to the screening method of the disclosure, drugs targeting RNA can be efficiently screened even with a very small amount sample of picomolar concentration. The discovered drugs targeting RNA can be used in the treatment of diseases associated with RNAs.
    Type: Application
    Filed: March 28, 2023
    Publication date: September 28, 2023
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Seung-Wook CHI, Mi-Kyung Lee, Donghwa Lee, Sohee Oh
  • Publication number: 20230303965
    Abstract: The present invention relates to a novel Lactobacillus reuteri DS0384 strain and the use of thereof.
    Type: Application
    Filed: June 23, 2021
    Publication date: September 28, 2023
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Mi-Young SON, Doo-Sang PARK, Kwang Bo JUNG, Hana LEE
  • Patent number: 11767297
    Abstract: The present disclosure provides the compound having inhibitory property against TNIK having a specific chemical structure or its pharmaceutically acceptable salt. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating or preventing cancer. The present disclosure also provides a method of treatment or prevention of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment or prevention.
    Type: Grant
    Filed: September 7, 2022
    Date of Patent: September 26, 2023
    Assignees: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY
    Inventors: Sung Youn Chang, Hyuk Lee, Ki Young Kim, Bum Tae Kim, Sung Soo Kim, Seong Hwan Kim, Hwan Jung Lim, Jung Nyoung Heo, Sang Joon Shin, Sang Youn Park
  • Patent number: 11767318
    Abstract: The present invention relates to a novel cathode buffer layer material and an organic photoelectric device including the same. When the novel compound of the present invention is applied to a cathode buffer layer of an organic photoelectric device, for example, an organic solar cell or an organic photodiode, there is an effect in which the surface characteristics of an electron transport layer are improved through the high dipole moment of the novel compound to thereby facilitate electron extraction from a photoactive layer to a cathode electrode and to reduce series resistance and leakage current, and accordingly, the performance of an organic optoelectronic device (organic solar cell, organic photodiode, etc.) to be manufactured can be remarkably improved, which is industrially advantageous.
    Type: Grant
    Filed: July 17, 2018
    Date of Patent: September 26, 2023
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Sung Cheol Yoon, Chang Jin Lee, Jaemin Lee, Seung Hun Eom
  • Patent number: 11766204
    Abstract: The present invention provides a magnetic monitoring system for imaging, monitoring, scanning or mapping for brain or heart activity of subjects including children and adults, the system comprising of a magnetoencephalographic or magnetocardiographic system incorporating SQUID sensors for measuring brain activity or heart activity, the system including a plurality of Dewar helmets of variable sizes and shapes; and a plurality of monitoring interfaces; wherein the sensor system helmet is moveable by horizontal Dewar rotation. The sensor system includes configurations where the size and shape of helmets in the system may be different to accommodate different sized subjects for monitoring simultaneously.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: September 26, 2023
    Assignee: The Korea Research Institute of Standards and Science (“KRISS”)
    Inventors: David Burton, Kwon Kyu Yu, Yong-Ho Lee, Hyuk Chan Kwon, Jin Mok Kim, Sang Kil Lee
  • Publication number: 20230294981
    Abstract: A low-temperature dehydrogenation method includes a dehydrogenation reaction of a reactant including a piperidine-based compound substituted with one or more alkyl groups. The dehydrogenation reaction takes place in the presence of a catalyst including an active metal. The active metal includes platinum (Pt), palladium (Pd), or a mixture thereof that is supported on a carrier including a composite metal oxide having alumina (Al2O3) and an additional metal oxide different from alumina, at a low temperature of 150° C. to 250° C., to produce hydrogen.
    Type: Application
    Filed: November 7, 2022
    Publication date: September 21, 2023
    Applicants: HYUNDAI MOTOR COMPANY, KIA CORPORATION, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Jihui Seo, Jaeyong Lee, Pyung Soon Kim, Jin Woo Choung, Yongwoo Kim, Ji Hoon Park, Soo Min Kim, Jeong Jae Lee, Kwanyong Jeong
  • Publication number: 20230295090
    Abstract: Provided is a method for synthesizing bipyridine that includes performing a dimerization reaction of a reactant including a piperidine-based compound, a pyridine-based compound, or a mixture thereof in the presence of a catalyst in which an active metal is supported on a composite metal oxide support including silica (SiO2) and alumina (AI2O3).
    Type: Application
    Filed: August 22, 2022
    Publication date: September 21, 2023
    Applicants: HYUNDAI MOTOR COMPANY, KIA CORPORATION, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Jihui Seo, Jaeyong Lee, Pyung Soon Kim, Jin Woo Choung, Yongwoo Kim, Ji Hoon Park, Soo Min Kim, Jeong Jae Lee, Kwanyong Jeong
  • Patent number: 11753510
    Abstract: A biodegradable composite material which is produced by polymerizing a mixture of an aqueous dispersion of a natural polymer nanofiber including any one or more of a chitin nanofiber and a cellulose nanofiber, a dicarboxylic acid or a derivative thereof, and a diol. The biodegradable composite material has excellent biodegradable and mechanical properties.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: September 12, 2023
    Assignee: Korea Research Institute of Chemical Technology
    Inventors: Sung Yeon Hwang, Jeyoung Park, Dong Yeop Oh, Tae Ho Kim, Si Gyeong Lee, Myung Suk Shin, Jong Geon Jegal
  • Publication number: 20230278944
    Abstract: The present invention relates to a method for preparing a perfluorodialkyl ether, comprising the steps of: (A) preparing a perfluorodialkyl ether from a compound represented by Formula 1 in the presence of a metal fluoride; and (B) isolating the perfluorodialkyl ether, and to an apparatus for preparing perfluorodialkyl ether, comprising: a reactor for preparing a perfluorodialkyl ether from a compound represented by Formula 1 in the presence of a metal fluoride; a reactant supplier for introducing the compound represented by Formula 1 into the reactor; and a discharge unit for discharging the perfluorodialkyl ether from the upper portion of the reactor.
    Type: Application
    Filed: July 26, 2021
    Publication date: September 7, 2023
    Applicants: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY, KOREA ELECTROTECHNOLOGY RESEARCH INSTITUTE
    Inventors: Sang Goo LEE, In Joon PARK, Won Wook SO, Shin Hong YOOK, Hong Suk KANG, Eun Ho SOHN, Ki Dong SONG, Yeon Ho OH, Hyun Jae JANG
  • Publication number: 20230271144
    Abstract: The present disclosure relates to a composite membrane in which a rubbery polymer is introduced into a gutter layer to suppress the physical aging of the highly permeable composite membrane, and more particularly, to a composite membrane comprising a porous support layer; a gutter layer on the porous support layer; and an active layer on the gutter layer, wherein the gutter layer comprises a blend of poly(l-trimethlsilyl-l-propyne) (PTMSP) and a rubbery polymer and a method for preparing the same. The composite membrane according to the present disclosure has high permeation performance and a remarkable decline in physical aging leading to a decrease in permeability over time and thus has very high industrial applicability.
    Type: Application
    Filed: July 15, 2021
    Publication date: August 31, 2023
    Applicant: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Su Young MOON, Jong Myeong LEE, Bong Jun CHANG, Chang In KONG, Jae-Hyeok LEE
  • Patent number: 11738063
    Abstract: The present invention relates to a pharmaceutical composition and health functional food for preventing or treating neurodegenerative diseases which include a flower extract of Daphne genkwa or fractions thereof as an active ingredient. The pharmaceutical composition and health functional food for preventing or treating neurodegenerative diseases are, not like extracts from stems and/or roots of Daphne genkwa, free from genotoxicity and have superior prophylactic or treatment effects against neurodegenerative diseases.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: August 29, 2023
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Won Gon Kim, Baek Soo Han, Jeong Su Byun, Ha Young Choi
  • Patent number: 11732232
    Abstract: The present disclosure provides a biomimetic cell culture apparatus that mimics interactions among organs in a human body. The present disclosure includes a plurality of culture units for culturing cells, a conduit for connecting the plurality of culture units to each other to form a circulating path, a pump unit disposed on the conduit for forming a flow in culture medium such that the culture medium circulates through the plurality of culture units, and an agitating module for agitating the plurality of culture units.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: August 22, 2023
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Cho Rok Jung, Jung Hwa Lim, Hyun Mi Kang, Kyung Hee Noh, Kyung Sook Chung, Mi Young Son, Myung Jin Son
  • Patent number: 11735397
    Abstract: Disclosed herein is a device for measuring a plasma ion density, which includes a transceiver antenna configured to apply and receive a microwave, of which a frequency is varied, to and from plasma, and a frequency analyzer configured to analyze a frequency of the microwave received from the transceiver antenna and measure a cut-off frequency, wherein the frequency of the microwave applied to the plasma is varied in the range of 100 kHz to 500 MHz.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: August 22, 2023
    Assignee: KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
    Inventors: Hyo Chang Lee, Jung Hyung Kim, Hee Jung Yeom
  • Patent number: 11723397
    Abstract: The techniques disclosed in the present specification relate to devices, systems, and methods using the same that generate cigarette smoke and then separate and collect substances of the cigarette smoke generated into particulate and gaseous substances for the preparation of a whole cigarette smoke condensate, which may comprise: a cigarette mount on which one or more cigarettes are mounted; an automatic ignition device for igniting the one or more cigarettes; a cigarette smoke collection unit for collecting substances of cigarette smoke generated from the ignited one or more cigarettes; one or more cigarette smoke intake lines configured to suck the cigarette smoke; one or more cigarette smoke exhaust lines configured to discharge the cigarette smoke; and one or more collection unit connecting lines connected to the cigarette smoke collection unit.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: August 15, 2023
    Assignee: KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Yong-Hyun Kim, Sung-Hwan Kim, Min-Seok Kim
  • Publication number: 20230248682
    Abstract: The present disclosure relates to a composition for preventing, alleviating or treating pruritus and/or atopy using an N-acetylamino acid or an N-acylamino acid having almost no side effects on the human body. Also, the present disclosure relates to a cosmetic composition for moisturizing skin or soothing skin. The composition of the present disclosure may be utilized to ameliorate a problematic skin condition caused by various causes, or to safely and effectively alleviate or treat pruritus and/or atopy without concern about side effects.
    Type: Application
    Filed: March 23, 2023
    Publication date: August 10, 2023
    Applicants: STEMDR INC., INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY, KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY
    Inventors: Myung-Kwan HAN, Kwangho LEE