Patents Assigned to Kumiai Chemical Industry Co., Ltd.
  • Patent number: 4814338
    Abstract: Disclosed are pyrimidine derivatives represented by general formula ##STR1## wherein Z.sup.1 represents an alkynyl group, an alkenyl group, an alkoxy group, an alkenyloxy group, or an alkynyloxy group which may be substituted with a halogen atom, and Z.sup.2 represents a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, or a group of the formula ##STR2## where Z.sup.3 represents a hydrogen atom or a methyl group; or its salt; and processes for preparing same. Also, agricultural or horticultural compositions containing the pyrimidine derivatives as active ingredient are disclosed, which show high controlling activities for cucumber gray mold (Botrytis cinerea), cucumber downey mildew (Pseudoperonospora cubensis), Alternaria sooty spot of Chinese mustard (Alternaria brassicicola), rice blast (Pyricularia oryzae), etc.
    Type: Grant
    Filed: October 29, 1986
    Date of Patent: March 21, 1989
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Shigekazu Ito, Katsumi Masuda, Shoji Kusano, Toshihiro Nagata, Yoshiyuki Kojima, Nobumitsu Sawai, Shin-ichiro Maeno
  • Patent number: 4770691
    Abstract: As new compounds are provided 2-(4',6'-di-substituted pyrimidine-2'-yl)oxy- or thio-benzoic acid derivatives of the formula ##STR1## wherein R is hydrogen, hydroxy, alkoxy, alkenyloxy, alkylthio or other substituents, R.sup.1 and R.sup.2 are each a halo, alkyl, alkoxy or other substituents; and X is oxygen or sulfur atom. These new compounds are useful as herbicidal agent effective to inhibit the growth of annual weeds and also perennial weeds predominant in irrigated fields of aquatic rice plants and in plowed fields.
    Type: Grant
    Filed: October 15, 1986
    Date of Patent: September 13, 1988
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Yukio Nezu, Kazuhiko Sugiyama, Shoji Kusano, Yasufumi Toyokawa, Takeshige Miyazawa, Ikuo Kajiwara
  • Patent number: 4757081
    Abstract: New substituted derivatives of 1,2,6-triphenyl-4(1H)-pyridinone are now provided, which are useful as fungicidal agent having practically valuable and improved fungicidal activities against a variety of phyto-pathogenic microorganisms, especially fungi and which show low toxicity to animals, including humans. These new compounds may be produced by different processes.
    Type: Grant
    Filed: March 26, 1987
    Date of Patent: July 12, 1988
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Norihisa Yonekura, Takashi Yumita, Yukio Nezu, Yoshiyuki Kojima, Shin-ichiro Maeno, Shigeharu Yaguchi
  • Patent number: 4742063
    Abstract: It is disclosed that a class of 5H-1,3,4-thiadiazolo[3,2-a]pyrimidin-5-one derivatives exhibit remarkable fungicidal activities for cucumber gray mold, cucumber downy mildew, Alternaria sooty spot of Chinese mustard, rice blast, etc.
    Type: Grant
    Filed: March 18, 1987
    Date of Patent: May 3, 1988
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Yukio Tokunaga, Yoshiyuki Kojima, Shinichiro Maeno, Nobumitsu Sawai, Yasuo Saso
  • Patent number: 4736038
    Abstract: 5,6-dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives represented by the following general formula [I] ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are either the same or different and mean individually a hydrogen atom or lower alkyl group, Y denotes a specific phenyl-containing substituted amino group, and their salts. These compounds have excellent immuno-modulating activities.
    Type: Grant
    Filed: October 23, 1986
    Date of Patent: April 5, 1988
    Assignees: Kumiai Chemical Industry Co., Ltd., Toyo Jozo Co., Ltd.
    Inventors: Itaru Yamamoto, Kenji Matsunari, Koyata Nitta, Kensuke Shibata, Noriyasu Takayanagi
  • Patent number: 4678496
    Abstract: As new compound is provided a cyclohexane derivative of the formula ##STR1## wherein R represents a hydrogen atom or an alkyl group, an alkylthioalkyl group or an unsubstituted or substituted phenyl group; and R.sup.1 represents an alkyl group, an unsubstituted or substituted benzyl group, a phenethyl group, a phenoxymethyl group, a 2-thienylmethyl group, an alkoxymethyl group or an alkylthiomethyl group, or a salt of said cyclohexane compound.This cyclohexane compound exhibits useful plant-growth regulating effects on crop-plants and also non-crop plants such as lawn and may be prepared by cyclization of an acetonylsuccinic acid dialkyl ester, followed by reaction with an organic acid chloride and by intermolecular rearrangement.
    Type: Grant
    Filed: August 1, 1985
    Date of Patent: July 7, 1987
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Kenji Motojima, Takeshige Miyazawa, Yasufumi Toyokawa, Masafumi Matsuzawa, Hiroshi Hokari, Shoji Kusano
  • Patent number: 4659371
    Abstract: A trifluoromethanesulfonanilide compound having the formula: ##STR1## wherein each of R.sup.1 and R.sup.2 is a lower alkyl group, X is a halogen atom or a trifluoromethyl group, n is an integer of 0 to 2, and R.sup.1 and R.sup.2 may form, together with the adjacent carbon atom, a ring which may be substituted by a lower alkyl group.
    Type: Grant
    Filed: June 9, 1986
    Date of Patent: April 21, 1987
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Tetsuo Takematsu, Makoto Konnai, Kuniaki Shimizu, Ikumi Urushibata, Ikuo Kajiwara
  • Patent number: 4629793
    Abstract: Compounds of the formula wherein R is ##STR1## in which R.sub.1, R.sub.2 and R.sub.3 are the same or different and are selected from the group consisting of hydrogen, chlorine, bromine, lower alkyl, lower alkoxy and naphthyl, provided that when R.sub.1 is lower alkyl, R.sub.2 and R.sub.3 are hydrogen, chlorine, bromine or lower alkoxy, or a pharmaceutically acceptable salt thereof, have anti-carrageenin edema activity, and are useful as anti-inflammatory agents and immuno modulators. They are produced by reacting an amide of the formula ##STR2## wherein R has the same meanings hereinabove, with N,N'-ethylene thiourea.
    Type: Grant
    Filed: June 5, 1985
    Date of Patent: December 16, 1986
    Assignees: Toyo Jozo Kabushiki Kaisha, Kumiai Chemical Industry Co., Ltd.
    Inventors: Kazuo Nishio, Isao Chiyomaru, Katsuo Anma, Kazuko Yamamoto, Hiroshi Ohno, Noriyasu Takayanagi
  • Patent number: 4560403
    Abstract: As new compound is provided a cyclohexane derivative of the formula ##STR1## wherein R represents a hydrogen atom or an alkyl group, an alkylthioalkyl group or an unsubstituted or substituted phenyl group; and R.sup.1 represents an alkyl group, an unsubstituted or substituted benzyl group, a phenethyl group, a phenoxymethyl group, a 2-thienylmethyl group, an alkoxymethyl group or an alkylthiomethyl group, or a salt of said cyclohexane compound.This cyclohexane compound exhibits useful plant-growth regulating effects on crop-plants and also non-crop plants such as lawn and may be prepared by cyclization of an acetonylsuccinic acid dialkyl ester, followed by reaction with an organic acid chloride and by intermolecular rearrangement.
    Type: Grant
    Filed: September 22, 1983
    Date of Patent: December 24, 1985
    Assignees: Kumiai Chemical Industry Co., Ltd., Ihara Chemical Industry Co., Ltd.
    Inventors: Kenji Motojima, Takeshige Miyazawa, Yasufumi Toyokawa, Masafumi Matsuzawa, Hiroshi Hokari, Shoji Kusano
  • Patent number: 4406894
    Abstract: An insect pesticidal composition comprises O,O-di-C.sub.2-3 alkyl S-benzyl- or S-halobenzyl-phosphorothiolate and a pyrethroid compound having the formula ##STR1## wherein X represents hydrogen atom or ethynyl group as active ingredients.
    Type: Grant
    Filed: September 29, 1981
    Date of Patent: September 27, 1983
    Assignees: Kumiai Chemical Industry Co., Ltd., Kuraray Co., Ltd.
    Inventors: Haruki Ogawa, Tomonori Shimazu
  • Patent number: 4392883
    Abstract: A herbicidal composition is provided which is characterized by the combination use as active ingredients of a thiocarbamate derivative of formula I: ##STR1## wherein one of X and Y is a hydrogen and the other is a chlorine and 4-amino-3-methyl-6-phenyl-1,2,4-triazin-5(4H)-one of the formula: ##STR2## Also provided is a process of inhibiting the growth of unwanted plants by applying the herbicidal composition to the plants or to the soil where the plants are grown.
    Type: Grant
    Filed: February 23, 1981
    Date of Patent: July 12, 1983
    Assignee: Kumiai Chemical Industry Co. Ltd.
    Inventors: Shinichi Iori, Ikuo Kajiwara, Kazuo Jikihara
  • Patent number: 4360375
    Abstract: A herbicidal composition which comprises a phenoxyphenoxy unsaturated derivative having the formula: ##STR1## wherein X represents a halogen atom or CF.sub.3 ; Y represents a hydrogen atom or a halogen atom; and Z represents --COOR, --COR", --COOH, --CH.sub.2 OH, or --CH.sub.2 OR"'.
    Type: Grant
    Filed: December 23, 1980
    Date of Patent: November 23, 1982
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Kazuo Jikihara, Shigekazu Itoh, Shuichi Takayama, Koichi Sato, Ichiro Kimura, Isao Chiyomaru
  • Patent number: 4303653
    Abstract: Organic phosphoric acid ester derivatives represented by the formula (I): ##STR1## wherein R and R', which may be the same or different, each represents an alkyl group, and A represents a group of atoms necessary to complete together with the two carbon atoms to which they are attached, a 6-membered heterocyclic group containing an oxygen atom as a heteroatom; a process for preparing the same and insecticidal, miticidal or nematocidal compositions containing the same as an active ingredient are disclosed; the compositions exhibit a high ability to control insect pests, mites, nematodes and unhygienic insects harmful to agricultural and horticultural crops.
    Type: Grant
    Filed: June 27, 1981
    Date of Patent: December 1, 1981
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Isao Chiyomaru, Hidetoshi Sugiyama, Koyata Niita, Kunihiko Fujimori, Tadayoshi Hirano, Osamu Tada
  • Patent number: 4276286
    Abstract: The invention relates to a process for decreasing the ammonia concentration in the interior of the body of domestic animals and fowls, thereby maintaining said animals and fowls in physiologically good condition and decreasing the ammonia concentration in the excrement thereof to decrease the offensive odor generated from the excrement. This is carried out by giving them the antibiotic multhiomycin in the feed or the drinking water containing multhiomycin.
    Type: Grant
    Filed: January 15, 1980
    Date of Patent: June 30, 1981
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Eisuke Ishihara, Hiroshi Yonehara, Katsuyuki Akasaki, Masao Minowa, Katsumi Kobayashi
  • Patent number: 4263040
    Abstract: A herbicidal composition which comprises a herbicidally effective amount of a phenoxyphenoxy derivative having the formula ##STR1## wherein X represents a halogen atom or CF.sub.3 ; Y represents a hydrogen atom or a halogen atom; and Z represents --COSR.sup.1 and R.sup.1 represents lower alkyl, phenyl, chlorophenyl, chlorobenzyl or methoxybenzyl; in combination with a suitable carrier is disclosed.
    Type: Grant
    Filed: January 25, 1979
    Date of Patent: April 21, 1981
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Kazuo Jikihara, Shigekazu Itoh, Shuichi Takayama, Koichi Sato, Ichiro Kimura, Isao Chiyomaru
  • Patent number: 4243661
    Abstract: The present invention relates to a veterinary medicine containing multhiomycin as an effective ingredient and provides a medicine for promoting growth of animals including birds, fishes and shellfishes and preventing various kinds of diseases of animals or fishes and shellfishes which contains multhiomycin as an essential component.
    Type: Grant
    Filed: April 23, 1979
    Date of Patent: January 6, 1981
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Eisuke Ishihara, Hiroshi Yonehara, Katsuyuki Akasaki, Masao Minowa, Katsumi Kobayashi
  • Patent number: 4229539
    Abstract: A new .beta.-galactosidase is now provided which is highly effective to digest lactose and stable at acidic pH values and thermally stable. The .beta.-galactosidase is produced by Penicillium multicolor in high yield and is isolated from the culture medium of this microorganism in an inexpensive and easy way.
    Type: Grant
    Filed: January 26, 1979
    Date of Patent: October 21, 1980
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Tan Miwa, Reisuke Kobayashi, Kiyoshi Takita
  • Patent number: 4229535
    Abstract: The present invention relates to a method of cultivation and extraction of multhiomycin, an antibiotic, and relates also to a veterinary medicine containing multhiomycin as an effective ingredient and more particularly, the present invention provides a method for obtaining multhiomycin by cultivating a multhiomycin-producing fungus such as Streptomyces sp. 8446-CC1 belonging to genus Streptomyces in a culture medium containing a sulfur-containing amino acid and treating the culture medium with a mixed solvent of alcohols and halogenated hydrocarbons or ketones and provides a medicine for promoting growth of animals and preventing various kinds of diseases of animals which contains multhiomycin as an essential component.
    Type: Grant
    Filed: April 3, 1978
    Date of Patent: October 21, 1980
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Eisuke Ishihara, Hiroshi Yonehara, Katsuyuki Akasaki, Masao Minowa, Katsumi Kobayashi
  • Patent number: 4222765
    Abstract: Thiolcarbamic acid esters having the formula ##STR1## wherein X represents hydrogen or chlorine atom and n represents an integer of 2 to 3 are disclosed.
    Type: Grant
    Filed: June 6, 1978
    Date of Patent: September 16, 1980
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Shuichi Takayama, Takehito Ishikawa, Ichiro Kimura, Syozi Shigematu
  • Patent number: 4163661
    Abstract: Trifluoromethylphenoxy phenoxy crotonic acid derivatives of the formula ##STR1## wherein X represents hydrogen or halogen atom, and R represents an alkyl, haloalkyl, alkenyl haloalkenyl or alkynyl group are disclosed. These compounds disclose herbicidal activity.
    Type: Grant
    Filed: June 26, 1978
    Date of Patent: August 7, 1979
    Assignee: Kumiai Chemical Industry Co., Ltd.
    Inventors: Kazuo Jikihara, Shigekazu Itoh, Shuichi Takayama, Koichi Sato, Ichiro Kimura, Isao Chiyomaru