Abstract: A method for promoting expression of calreticulin in at least one kind of eukaryotic cell, and a synthetic peptide useful in this method are provided. In the method provided by the present invention, a culture of target cells is prepared, and a calreticulin expression-promoting peptide having calreticulin expression-promoting activity is supplied at least once to that culture.

Abstract: A computer calculates a change amount of a total number of electrons from an observation start time in the ionosphere between an observation station and a satellite based on observation data of a signal received from the satellite by the observation station on the ground. The computer estimates the change amount of the total number of electrons to be calculated next based on the time change of the change amount of the total number of electrons from the observation start time in the ionosphere and calculates a difference (estimation error) between the estimated change amount of the total number of electrons and the actually calculated change amount of the total number of electrons. The computer calculates a correlation value between the estimation error calculated for each observation station and the estimation error calculated for a predetermined number of the observation stations in the vicinity of each observation station.

Abstract: A bone treatment guide, a bone treatment guide set, and a method for using a bone treatment guide are provided that enable a treatment tool, such as a trephine, to be accurately disposed relative to a bone of a patient, and that can keep a positioning member, such as a guide pin, from affecting treatment using the treatment tool. A parallel guide 5 has a positioning guide portion 13 that is to be connected to a guide pin 2, which is to be temporarily fixed to a patient's femur 101, and a treatment tool guide portion 14 configured to be able to guide a trephine 3 for treating the femur 101 toward a position at which the trephine 3 is to enter the inside of the femur 101 and in an entering direction, the treatment tool guide portion 14 being arranged in an area different from the positioning guide portion 13.

Abstract: In a case where passivity-based control is applied to a plurality of circuits connected in parallel, a simpler target state is used. A switching power supply system includes: a plurality of switching power supply circuits connected in parallel to a load R; and a controller configured to switch each of the plurality of switching power supply circuits, through passivity-based control, by using a sum of currents that flow in the plurality of switching power supply circuits.

Abstract: The present invention provides a production method of oxo fatty acid, as well as rare fatty acids such as conjugated fatty acid, hydroxylated fatty acid, partially saturated fatty acid and the like, which uses 4 kinds of enzymes (fatty acid-hydratase, hydroxylated fatty acid-dehydrogenase, oxo fatty acid-isomerase, oxo fatty acid-enone reductase) derived from Lactobacillus plantarum including lactic acid bacteria and the like. Furthermore, the present invention also provides a more efficient production method of oxo fatty acid and the like, which partly uses a chemical oxidation reaction in combination.

Abstract: Provided is a method for preventing, ameliorating, suppressing the progression of, and/or treating a tumor caused by a tumor virus, the method including the step of administering, to a subject, an effective amount of a component that targets a gene product of the tumor virus.

Abstract: A light-emitting section (21) emits light to be irradiated on a body of a patient (100). A light-receiving section (22) outputs a signal corresponding to an intensity of light which has been transmitted through or reflected from the body of the patient (100). A pulse-amplitude Index acquiring section (32) analyzes amplitude of the signal to acquire a pulse-amplitude Index of the patient (100). A pulse determining section (33) determines presence or absence of a pulse of the patient (100) in accordance with the pulse-amplitude Index. A notifying section (34) notifies a result of determination made by the pulse determining section (33).

Abstract: A method for evaluating an efficacy of a chemoradiotherapy against squamous cell carcinoma comprises the following steps (a) to (c): (a) detecting an expression level of at least one gene selected from a SIM2 gene and genes co-expressed with the SIM2 gene in a squamous cell carcinoma specimen isolated from a subject; (b) comparing the expression level detected in the step (a) with a reference expression level of the corresponding gene; and (c) determining that an efficacy of a chemoradiotherapy against squamous cell carcinoma in the subject is high if the expression level in the subject is higher than the reference expression level as a result of the comparison in the step (b).

Abstract: This invention provides a method for stably producing alveolar epithelial progenitor cells from pluripotent stem cells, including steps of culturing pluripotent stem cells in (1) a medium containing activin A and a GSK3? inhibitor, (2) a medium containing a BMP inhibitor and a TGF? inhibitor, and (3) a medium containing BMP4, retinoic acid, and a GSK3? inhibitor.

Abstract: The invention provides a metabolism improving agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the metabolism improving agent.

Abstract: The present invention provides a derivative of hydroxylated fatty acid which has a high content of hydroxylated fatty acid, and permits easy ingestion and easy handling, and a production method thereof. The present invention provides a method for producing a homopolymer of hydroxylated fatty acid, including polymerizing the hydroxylated fatty acid by using an enzyme. The homopolymer of hydroxylated fatty acid is stabilized. In addition, a novel, utilizable homopolymer of hydroxylated fatty acid obtained by this production method is also provided.

Abstract: The present invention provides a highly functional platelet production promoting agent which comprises one or a plurality of aryl hydrocarbon receptor (AhR) antagonists and one or a plurality of Rho-associated coiled-coil forming kinase (ROCK) inhibitors.

Abstract: Mesenchymal stem cells may be culture for a long period, without using any special apparatus, equipment and the like, in a medium in which seven kinds of nonessential amino acids of glycine, alanine, serine, proline, asparagine, aspartic acid, and glutamic acid are reduced.

Abstract: The present invention provides an anti-inflammatory agent containing a rare fatty acid such as hydroxylated fatty acid, oxo fatty acid and the like, and further, food, pharmaceutical product and the like containing the anti-inflammatory agent.

Abstract: The present invention provides: a platelet production promoter that contains one or more substances selected from the group consisting of Wnt inhibitors and FMS-like tyrosine kinase (FLT) inhibitors; and a platelet production method that uses this platelet production promoter.

Abstract: An object of the present invention is to provide a method for removing highly proliferative Ki67-positive cells co-present in insulin-secreting cells obtained by differentiation induction. A method for producing an insulin-producing cell population or a pancreatic beta cell population containing less than 3% of Ki67-positive cells, comprising: embedding an endocrine progenitor cell population or a cell population at a later stage of differentiation into a gel containing alginic acid; and differentiating the cell population.

Abstract: The inventors have found that VCP inhibitors protect corneal endothelial cells and corneal epithelial cells. Accordingly, the disclosure provides a composition for protecting a cornea comprising a compound of formula (I) or an ester, oxide, pharmaceutically acceptable salt or solvate thereof. In another aspect the disclosure provides a composition for treating and/or preventing a corneal disease comprising a compound of formula (I). In a further aspect the disclosure provides a composition for ocular irrigation comprising a compound of formula (I). In a still further aspect the disclosure provides a composition for preserving a corneal graft comprising a compound of formula (I).

Abstract: Provided is a communication device in which: a wireless network is formed of at least one sub-tree including a sub-root station; the sub-root station collects request wireless resource allocation information which a child station included in the sub-tree has; request wireless resource allocation information of the sub-root station itself is added to the collected request wireless resource allocation information, and the resultant information is reported to a parent station, the parent station notifies the sub-root station of wireless resource information available in the entire sub-tree; and the sub-root station allocates wireless resources to the sub-root station itself and the child station based on the wireless resource information notification.

Abstract: To provide a two-dimensional photonic crystal surface emitting laser capable of improving characteristics of light to be emitted, in particular, optical output power. The two-dimensional photonic crystal surface emitting laser includes: a two-dimensional photonic crystal including a plate-shaped base member and modified refractive index regions where the modified refractive index regions have a refractive index different from that of the plate-shaped base member and are two-dimensionally and periodically arranged in the base member; an active layer provided on one side of the two-dimensional photonic crystal; and a first electrode and a second electrode provided sandwiching the two-dimensional photonic crystal and the active layer for supplying current to the active layer, where the second electrode covers a region equal to or wider than the first electrode.

Abstract: The complex comprising one or more of the compound represented by general formula: RPbn1Xm1 (wherein R is a cation represented by R1NH3+ (wherein R1 represents a univalent substituted or unsubstituted hydrocarbon group), or the following formula: (wherein R2 represents a hydrogen atom, or a univalent substituted or unsubstituted hydrocarbon group); X is the same or different, and each represents a halogen atom; n1 is 0.8 to 1.2; and m1 is 2.8 to 3.2, or the compound represented by general formula: R2Pbn2Xm2 wherein R and X are as defined above; n2 is 2.8 to 3.2; and m2 is 7.7 to 8.3; and one or more dimethylformamide molecules is capable of decreasing the stirring time upon dissolution in an organic solvent such as DMSO, as well as decreasing the hysteresis and improving the solar cell characteristics (in particular, photoelectric conversion efficiency) when the complex is applied to a perovskite layer.