Patents Assigned to Kyushu University
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Publication number: 20240374561Abstract: The present invention provides a trisulfide-compound-containing agent for inhibiting nitration of tyrosine residues in hepatocyte growth factor, the trisulfide compound being: glutathione trisulfide or a pharmaceutically acceptable salt thereof; or a compound represented by formula (1) (wherein X represents —OR1 or —NR2R3, R1 represents a hydrogen atom or an alkyl group containing 1 to 6 carbon atoms, R2 and R3 independently represent a hydrogen atom or an alkyl group containing 1 to 6 carbon atoms, and the alkyl group may have one or more substituents selected from the group consisting of amino groups and carboxy groups), a pharmaceutically acceptable salt thereof, or a cyclodextrin clathrate thereof.Type: ApplicationFiled: September 8, 2022Publication date: November 14, 2024Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, KYOWA HAKKO BIO CO., LTD.Inventors: Ryuichi TATSUMI, Mako NAKAMURA, Etsuo OHSHIMA
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Patent number: 12136724Abstract: Provided is a low-cost catalyst that has excellent oxygen reduction reaction (ORR) catalytic activity and is useful as a catalyst for water electrolysis, an electrode catalyst for an air battery, or the like. The catalyst includes (A) Ni atoms, (B) a condensate of thiourea and formaldehyde, and (C) porous carbon.Type: GrantFiled: April 15, 2020Date of Patent: November 5, 2024Assignees: ZEON CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Naotoshi Nakashima, Ganesan Pandian, Hiroaki Shu, Mitsugu Uejima
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Patent number: 12136256Abstract: A learning apparatus (500) according to the present invention includes a detection unit (510) that detects, as a candidate region of a learning target, a region detected by one of first detection processing of detecting an object region from a predetermined image and second detection processing of detecting a change region from background image information and the image, and not detected by the other, an output unit (520) that outputs at least a part of the candidate region as a labeling target, and a learning unit (530) that learns a model for performing the first detection processing or a model for performing the second detection processing by using the labeled candidate region as learning data.Type: GrantFiled: June 17, 2020Date of Patent: November 5, 2024Assignees: NEC CORPORATION, Kyushu University, National University CorporationInventors: Takashi Shibata, Hiroyoshi Miyano, Eiji Kaneko, Masato Toda, Tsubasa Minematsu, Atsushi Shimada, Rin-Ichiro Taniguchi
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Publication number: 20240351902Abstract: Provided is a calcium carbonate generation method and system in which calcium carbonate having a high purity can be generated using a calcium-containing waste. Provided is a calcium carbonate generation method of generating calcium carbonate from a calcium-containing waste, the calcium carbonate generation method including: a calcium dissolution step of adding aqueous hydrochloric acid to a calcium-containing waste and dissolving calcium to generate an aqueous solution containing a calcium ion; a separation step of adjusting a hydrogen ion concentration index of the aqueous solution containing a calcium ion and separating a component containing at least one selected from the group consisting of Si, Al, Mg, and heavy metal from the aqueous solution; and a calcium carbonate collection step of generating calcium carbonate using an aqueous solution obtained in the separation step and an aqueous solution containing potassium carbonate and/or sodium carbonate.Type: ApplicationFiled: August 31, 2022Publication date: October 24, 2024Applicants: SUMITOMO OSAKA CEMENT CO., LTD., YAMAGUCHI UNIVERSITY, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Sadato KIKUCHI, Shogo NAKAMURA, Risa OIZUMI, Masayoshi KONISHI, Mitsuru HIGA, Ikuo TANIGUCHI
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Publication number: 20240352161Abstract: A a crosslinkable polymer composition which provides a crosslinked product capable of both heat resistance and re-formability, a crosslinked polymer material capable of both heat resistance and re-formability, and an insulated wire and a wiring harness including the crosslinked polymer material. The crosslinkable polymer composition includes: ingredient A from which metal ion is released by heat; and ingredient B including an organic polymer having a side chain, including an electron-withdrawing substituent group capable of forming an ionic bond with the metal ion, and when B is crosslinked via the metal ion to form a crosslinked product, the product has a flow starting temperature of 190° C. or higher and 300° C. or lower. The crosslinked polymer material includes the crosslinked product of the crosslinkable polymer composition. The insulated wire includes a wire conductor, and an insulation coating including the crosslinked polymer material, and the wiring harness including the insulated wire.Type: ApplicationFiled: August 29, 2022Publication date: October 24, 2024Applicants: AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Masashi SATO, Takehiro HOSOKAWA, Yasuyuki OTSUKA, Tatsuya SHIMADA, Tatsuya HASE, Makoto MIZOGUCHI
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Patent number: 12122768Abstract: A compound represented by formula (I). In formula (I), each L independently represents a substituted or unsubstituted aryl group, or a substituted or unsubstituted heteroaryl group, n indicates the number of L groups, and is either 1 or 2, each Q independently represents a substituted or unsubstituted 3,6-di-t-butyl-9H-carbazol-9-yl group, a substituted or unsubstituted 3,6-diphenyl-9H-carbazol-9-yl group, or a substituted or unsubstituted 3-phenyl-6-t-butyl-9H-carbazol-9-yl group, and in indicates the number of Q groups, and has a value of 5?n.Type: GrantFiled: August 29, 2019Date of Patent: October 22, 2024Assignees: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NIPPON SODA CO., LTD.Inventors: Takuma Yasuda, In Seob Park, Katsunori Tanaka, Yasuhiro Miyashita, Yasuhiko Ashikari
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Patent number: 12125611Abstract: Provided are a surface protection composition which has excellent anticorrosion performance to prevent the metal corrosion, and also has excellent coating properties and heat resistance with suppressing cracks from being occurred even in a cold environment and maintaining anticorrosion performance, and a terminal-fitted electric wire using these. The present protection composition contains: (a) a phosphorus compound represented by the following general formula (1) in an amount of 0.1 to 10 mass % in terms of phosphorus element with respect to the total amount of the composition; (b) a metal-containing compound in an amount of 0.1 to 10 mass % in terms of the metal element with respect to the total amount of the composition or an amine compound in an amount of 0.1 to 5.0 mass % in terms of nitrogen element with respect to the total amount of the composition; (c) a (meth) acrylate having two or more carbon-carbon double bonds and hydrocarbon chains having four or more carbon atoms in an amount of 1.Type: GrantFiled: November 11, 2019Date of Patent: October 22, 2024Assignees: AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Naoyuki Oshiumi, Takehiro Hosokawa, Makoto Mizoguchi
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Publication number: 20240343843Abstract: A crosslinkable polymer composition which provides a crosslinked product capable of both heat resistance and re-formability, a crosslinked polymer material capable of both heat resistance and re-formability, and an insulated wire and a wiring harness including the crosslinked polymer material. The crosslinkable polymer composition includes: ingredient A from which metal ion is released by heat; and ingredient B including an organic polymer having a side chain, including an electron-withdrawing substituent group capable of forming an ionic bond with the metal ion, and when B is crosslinked via the metal ion to form a crosslinked product, the product has a flow starting temperature of 190° C. or higher and 300° C. or lower. The crosslinked polymer material includes the crosslinked product of the crosslinkable polymer composition. The insulated wire includes a wire conductor, and an insulation coating including the crosslinked polymer material, and the wiring harness including the insulated wire.Type: ApplicationFiled: August 29, 2022Publication date: October 17, 2024Applicants: AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Masashi SATO, Takehiro HOSOKAWA, Tatsuya SHIMADA, Makoto MIZOGUCHI
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Patent number: 12110415Abstract: A surface protection composition contains (a) a phosphorus compound represented by formula (1), wherein R1 represents a hydrogen atom, R2 represents a hydrocarbon group having 4 to 30 carbon atoms, and R3 represents a hydrogen atom or a hydrocarbon group having 4 to 30 carbon atoms, (b-1) a metal-containing compound or (b-2) an amine compound, (c) a (meth)acrylate having a hydrocarbon chain having 4 or more carbon atoms, (d-1) an acylphosphine oxide photopolymerization initiator and (d-2) an ?-aminoacetophenone photopolymerization initiator, wherein the composition has the compound (d-1) in an amount of 0.1 to 3.0 mass % with respect to the total amount of the composition, compound (d-2) in an amount of 0.1 to 3.0 mass % with respect to the total amount of the composition and a total amount of the compound (d-I) and (d-2) is less than 5.0 mass % with respect to the total amount of the composition.Type: GrantFiled: November 25, 2020Date of Patent: October 8, 2024Assignees: AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Naho Yoshioka, Yutaka Takata, Naoyuki Oshiumi, Makoto Mizoguchi
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Patent number: 12111296Abstract: A supercritical fluid chromatograph includes a liquid sender that supplies a mobile phase including a supercritical fluid to a supply flow path, first and second back pressure regulators that are respectively provided in first and second flow paths into which a path from the liquid sender branches and an analysis column provided at a position farther upstream than the first back pressure regulator in the first flow path. An analysis assistance device includes a storage a receiver, a first calculator, and a presenter.Type: GrantFiled: July 20, 2021Date of Patent: October 8, 2024Assignees: SHIMADZU CORPORATION, MIYAZAKI PREFECTURE, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Yuka Fujito, Miho Sakai, Takeshi Bamba
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Publication number: 20240327947Abstract: Provided is a mineral processing method that allows obtaining a concentrate having a low arsenic grade from a raw material having a high arsenic grade.Type: ApplicationFiled: June 10, 2024Publication date: October 3, 2024Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, SUMITOMO METAL MINING CO., LTD.Inventors: Tsuyoshi HIRAJIMA, Hajime MIKI, Gde Pandhe Wisnu SUYANTARA, Keiko SASAKI, Yoshiyuki TANAKA, Eri TAKIDA
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Patent number: 12089494Abstract: An organic electroluminescent device having an anode, a cathode, and a light-emitting layer between the anode and the cathode, wherein the light-emitting layer contains at least a first organic compound, a second organic compound and a third organic compound satisfying the following formula (A), the second organic compound is a delayed fluorescent material, and the third organic compound is a light-emitting material, has a high light emission efficiency. Formula (A): ES1(A)>ES1(B)>ES1(C) wherein ES1(A), ES1(B) and ES1(C) each represent a lowest excited singlet energy level of the first organic compound, the second organic compound and the third organic compound, respectively.Type: GrantFiled: June 13, 2019Date of Patent: September 10, 2024Assignees: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, KYULUX, INC.Inventors: Hajime Nakanotani, Chihaya Adachi, Hiroki Noda, Yoshitake Suzuki, Naoto Notsuka, Hiroko Nomura, Ayataka Endo, Ping Kuen Daniel Tsang
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Publication number: 20240294952Abstract: A method for producing a microbial oil includes genetically modifying a labyrinthulid which belongs to the genus Parietichytrium or the genus Schizochytrium by disrupting and/or silencing a ?4 desaturase gene, a C20 elongase gene, and/or a C18 elongase gene, or by being transformed with an ?3 desaturase gene; culturing the labyrinthulid; and collecting the microbial oil from the labyrinthulid. The labyrinthulid has an activity of synthesizing DHA via a PUFA-PKS pathway in an amount of not more than 1/100 of a total amount of DHA synthesized in the labyrinthulid or no activity of producing PUFAs via the PUFA-PKS pathway, and the labyrinthulid has an activity of producing PUFAs via an endogenous elongase-desaturase pathway.Type: ApplicationFiled: January 12, 2024Publication date: September 5, 2024Applicants: KYUSHU UNIVERSITY, NAT'L UNIVERSITY CORPORATION, KONAN GAKUEN, NIPPON SUISAN KAISHA, LTD.Inventors: Yuji Okita, Makoto Ito, Rie Hamaguchi, Hatsumi Goda, Seiya Mochinaga, Daisuke Honda
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Publication number: 20240286980Abstract: Provided is a production method that enables simple and efficient production of a fluorinated hydrocarbon by a gas phase flow method without using a catalyst. The method of producing a fluorinated hydrocarbon includes continuously supplying a gaseous fluorine-containing inorganic compound to an electrical discharge zone in a plasma apparatus and subsequently causing migration to outside of the electrical discharge zone in the plasma apparatus, continuously supplying a feedstock gas containing an inert gas and a compound represented by formula 1: CH3—R (R is a hydrogen atom, a chlorine atom, a bromine atom, an iodine atom, or an organic group other than a hydrocarbon group) to outside of the electrical discharge zone in the plasma apparatus, and subsequently continuously releasing, to outside of the plasma apparatus, gas that is contained outside of the electrical discharge zone in the plasma apparatus.Type: ApplicationFiled: May 19, 2022Publication date: August 29, 2024Applicants: ZEON CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Go MATSUURA, Keita INADA, Takayuki WATANABE, Manabu TANAKA, Kazuki MATSUI
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Patent number: 12072507Abstract: A laser radiation optical system for laser doping and post-annealing, the laser radiation system including A. a laser apparatus configured to generate pulsed laser light that belongs to an ultraviolet region, B. a stage configured to move a radiation receiving object in an at least one scan direction, the radiation receiving object being an impurity source film containing at least an impurity element as a dopant and formed on a semiconductor substrate, and C. an optical system including a beam homogenizer configured to shape the beam shape of the pulsed laser light into a rectangular shape and generate a beam for laser doping and a beam for post-annealing that differ from each other in terms of a first beam width in the scan direction but have the same second beam width perpendicular to the scan direction.Type: GrantFiled: April 22, 2020Date of Patent: August 27, 2024Assignees: Gigaphoton Inc., Kyushu University, National University CorporationInventors: Osamu Wakabayashi, Hiroshi Ikenoue, Hiroaki Oizumi
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Patent number: 12074355Abstract: Provided is a catalyst that has excellent oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) catalytic activity and is useful as a catalyst for water electrolysis, an electrode catalyst for an air battery, or the like. The catalyst includes (A) either or both of Ni atoms and Fe atoms, (B) thiourea, and (C) fibrous carbon nanostructures. It is preferable that the catalyst includes (A) Ni atoms and Fe atoms, that the thiourea is coordinated with the Ni atoms and the Fe atoms, and that a mass ratio of the content of a Ni-thiourea coordination compound relative to the content of an Fe-thiourea coordination compound (Ni-thiourea coordination compound/Fe-thiourea coordination compound) is not less than 5/95 and not more than 70/30.Type: GrantFiled: April 15, 2020Date of Patent: August 27, 2024Assignees: ZEON CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Naotoshi Nakashima, Ganesan Pandian, Hiroaki Shu, Mitsugu Uejima
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Publication number: 20240277712Abstract: The present invention aims at therapeutics to treat and/or prevent Rett syndrome (RTT), autism spectrum disorders or schizophrenia for which no curative therapy has yet been found. The invention relates to pharmaceutical compositions for preventing or treating Rett syndrome (RTT), autism spectrum disorders, or schizophrenia, which comprises a reverse transcription inhibitor for retrotransposon L1.Type: ApplicationFiled: June 13, 2020Publication date: August 22, 2024Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Kinichi NAKASHIMA, Hideyuki NAKASHIMA, Alysson Renato MUOTRI
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Patent number: 12054747Abstract: A method of differentiating a primordial germ cell into a primordial follicle in vitro includes culturing a primordial germ cell and a supporting cell adjacent to the primordial germ cell under a pressurized condition or a low oxygen concentration condition.Type: GrantFiled: May 29, 2019Date of Patent: August 6, 2024Assignee: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Go Nagamatsu, Yohei Nishimura, So Shimamoto, Katsuhiko Hayashi
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Patent number: 12048175Abstract: An organic electroluminescent device having a structure of at least an anode 2, a light-emitting layer 3 and a cathode 4 layered in that order, wherein the light-emitting layer 3 contains a first host material, a second host material and a light-emitting material of a dopant, and both the first host material and the second host material have a lowest excited triplet energy level higher than the lowest excited triplet energy level of the light-emitting material. The device is protected from performance deterioration with time in driving and has a long lifetime.Type: GrantFiled: December 28, 2016Date of Patent: July 23, 2024Assignee: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Ping Kuen Daniel Tsang, Chihaya Adachi
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Publication number: 20240216390Abstract: Disclosed herein is a prophylactic or therapeutic agent for ocular fundus disease, especially diabetic retinopathy or age-related macular degeneration. The prophylactic or therapeutic agent for ocular fundus disease comprising: (S)-(-)-1-(4-fluoro-5-isoquinolinesulfonyl)-2-methyl-1,4-homopiperazine, a salt thereof, or a solvate thereof, as an active ingredient.Type: ApplicationFiled: March 15, 2024Publication date: July 4, 2024Applicants: KYUSHU UNIVERSITY, NAT'L UNIVERSITY CORPORATION, KOWA COMPANY, LTD.Inventors: Tatsuro Ishibashi, Shintaro Nakao, Ryoichi Arita, Ken Mizuno, Akifumi Tsuchiura