Patents Assigned to Kyushu University
  • Publication number: 20250115550
    Abstract: Provided is a method for producing sulfurized olefin, the method including reacting an olefin compound (a) represented by R1R2C?CHR3 . . . (1) (in Formula (1), R1 and R2 each are alkyl groups, respectively, R3 is a hydrogen atom or an alkyl group, and the total number of carbon atoms of R1, R2 and R3 is 2 to 20) with sulfur in the presence of hydrogen to give a dialkyl polysulfide (A).
    Type: Application
    Filed: February 15, 2023
    Publication date: April 10, 2025
    Applicants: DIC Corporation, Kyushu University, National University Corporation
    Inventors: Hironobu Matsueda, Hiroshi Sakata, Shujiro Otsuki, Eiji Yamamoto, Makoto Tokunaga, Haruno Murayama, Yuta Takaki, Yasutaka Kawai, Kei Takakura, Moemi Kimura
  • Publication number: 20250084467
    Abstract: A probe has a base sequence that does not hybridize with a nucleic acid of a mammal under stringent conditions, and has a sequence including a base sequence set forth in any of SEQ ID NOs:1 to 673. A probe set includes two or more kinds of the probes, and the two or more kinds of the probes do not hybridize with each other under stringent conditions.
    Type: Application
    Filed: June 30, 2022
    Publication date: March 13, 2025
    Applicant: Kyushu University, National University Corporation
    Inventor: Yasuyuki Ohkawa
  • Patent number: 12222166
    Abstract: A heat-transfer member (1) is used in a cooling system in which an alcohol serves as a coolant. The heat-transfer member (1) has: a heat-receiving surface (11) configured such that it can receive heat from a heat-generating body; and a heat-dissipating surface (12) configured such that it can dissipate, to the coolant, the heat received at the heat-receiving surface (11). The heat-dissipating surface (12) has a plurality of pores (121) whose average pore diameter is 5 nm or more and 1,000 nm or less. A cooling system can be configured by causing the coolant to contact the heat-dissipating surface (12) of the heat-transfer member (1).
    Type: Grant
    Filed: April 30, 2020
    Date of Patent: February 11, 2025
    Assignees: Kyushu University, National University Corporation, UACJ Corporation
    Inventors: Yasuyuki Takata, Koji Takahashi, Biao Shen, Junji Nunomura, Yoichiro Bekki, Akihiro Fukatsu
  • Patent number: 12195579
    Abstract: The present invention provides a cell adhesion sheet in which the adhesion of platelets is suppressed and the adhesion of cells is excellent. The cell adhesion sheet according to the embodiment of the present invention is formed of a composition containing a compound represented by Formula (1).
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: January 14, 2025
    Assignees: FUJIFILM Corporation, Kyushu University, National University Corporation
    Inventors: Yosuke Yamamoto, Yuta Shigenoi, Atsushi Sugasaki, Masaru Tanaka, Shingo Kobayashi
  • Publication number: 20250001009
    Abstract: Methods are disclosed herein for promoting survival of a donor liver in a recipient subject, wherein the donor liver is homozygous for rs738409:G mutation in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene. The method can include administering to the subject glutathione (GSH) and/or a nucleic acid molecule encoding a component of the ferroptosis pathway (such as GPX4).
    Type: Application
    Filed: November 21, 2022
    Publication date: January 2, 2025
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, Regents of the University of Michigan, Kyushu University, National University Corporation
    Inventors: Alejandro Soto-Gutierrez, Kazuki Takeishi, Kazutoyo Morita, Nils Haep, Rodrigo Machado Florentino, Abhinav Achreja, Deepak Nagrath, Olamide Animasahun, Tomoharu Yoshizumi
  • Patent number: 12136256
    Abstract: A learning apparatus (500) according to the present invention includes a detection unit (510) that detects, as a candidate region of a learning target, a region detected by one of first detection processing of detecting an object region from a predetermined image and second detection processing of detecting a change region from background image information and the image, and not detected by the other, an output unit (520) that outputs at least a part of the candidate region as a labeling target, and a learning unit (530) that learns a model for performing the first detection processing or a model for performing the second detection processing by using the labeled candidate region as learning data.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: November 5, 2024
    Assignees: NEC CORPORATION, Kyushu University, National University Corporation
    Inventors: Takashi Shibata, Hiroyoshi Miyano, Eiji Kaneko, Masato Toda, Tsubasa Minematsu, Atsushi Shimada, Rin-Ichiro Taniguchi
  • Patent number: 12072507
    Abstract: A laser radiation optical system for laser doping and post-annealing, the laser radiation system including A. a laser apparatus configured to generate pulsed laser light that belongs to an ultraviolet region, B. a stage configured to move a radiation receiving object in an at least one scan direction, the radiation receiving object being an impurity source film containing at least an impurity element as a dopant and formed on a semiconductor substrate, and C. an optical system including a beam homogenizer configured to shape the beam shape of the pulsed laser light into a rectangular shape and generate a beam for laser doping and a beam for post-annealing that differ from each other in terms of a first beam width in the scan direction but have the same second beam width perpendicular to the scan direction.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: August 27, 2024
    Assignees: Gigaphoton Inc., Kyushu University, National University Corporation
    Inventors: Osamu Wakabayashi, Hiroshi Ikenoue, Hiroaki Oizumi
  • Patent number: 11969597
    Abstract: A blood pressure controlling apparatus includes an acquiring part configured to acquire biological information indicating blood pressure of a subject, a producing part configured to produce a frequency modulated pulse train on the basis of the biological information, and a supplying part configured to supply an electrical current on the basis of the frequency modulated pulse train, to an electrode attached on the subject. The electrical current stimulates baroreceptor afferent nerves of the subject.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: April 30, 2024
    Assignee: Kyushu University, National University Corporation
    Inventors: Keita Saku, Kenji Sunagawa, Takeshi Tohyama, Kazuya Hosokawa, Takafumi Sakamoto
  • Publication number: 20230416709
    Abstract: It was found that four nuclease domain mutants have nuclease activity superior to that of a wild-type nuclease domain and are capable of enhancing genome editing efficiency in combination with various nucleic acid binding domains.
    Type: Application
    Filed: November 4, 2021
    Publication date: December 28, 2023
    Applicants: EDITFORCE, INC., Kyushu University, National University Corporation
    Inventors: Yusuke YAGI, Masaru OHTA, Takahiro NAKAMURA
  • Publication number: 20230377916
    Abstract: A machine learning method includes acquiring image data generated from reflected light of illumination light radiated to a first region of a semiconductor film on a substrate, the first region annealed by pulse laser light, acquiring data on a measured semiconductor property of the first region, generating training data including the image data as input and the measured data as output associated with each other, and performing machine learning using a neural network based on the training data to generate a learned model.
    Type: Application
    Filed: July 13, 2023
    Publication date: November 23, 2023
    Applicants: Kyushu University, National University Corporation, Gigaphoton Inc.
    Inventors: Hiroshi IKENOUE, Akira MIZUTANI
  • Publication number: 20230310355
    Abstract: The object of the present invention is to provide an inexpensive and effective sirtuin activator derived from natural products. The problem can be solved by a sirtuin activator comprising ?-alanine or a salt thereof, or a composition for activating sirtuin comprising the sirtuin activator as an active ingredient, of the present invention.
    Type: Application
    Filed: August 18, 2021
    Publication date: October 5, 2023
    Applicants: Yuki Gosei Kogyo Co., Ltd., Kyushu University, National University Corporation
    Inventors: Tetsuji NODA, Tomotsune ONAGA, Yoshinori KATAKURA
  • Publication number: 20230092815
    Abstract: The present disclosure is intended to enhance various effects of a green tea extract such as catechin in the most effective manner. The ratio (B/A) of epigallocatechin gallate (A) contained in the green tea extract and flavanone glycoside (B) contained in the citrus extract is 0.2<B/A<1.6, or a ratio (C/A) of epigallocatechin gallate (A) and eriocitrin (C) contained in the citrus extract is 0.2<C/A<0.5.
    Type: Application
    Filed: March 3, 2021
    Publication date: March 23, 2023
    Applicants: Toyota Jidosha Kabushiki Kaisha, Kyushu University, National University Corporation
    Inventors: Akari Nakasone, Madoka Abe, Hirofumi Tachibana
  • Publication number: 20230030314
    Abstract: The present invention discloses a method for diagnosing cancer comprising a step of detecting active protein kinase C? in urine.
    Type: Application
    Filed: December 4, 2020
    Publication date: February 2, 2023
    Applicant: Kyushu University, National University Corporation
    Inventors: Masaharu Murata, Takahito Kawano, Masatoshi Eto, Junichi Inokuchi, Jeong-Hun Kang
  • Patent number: 11545631
    Abstract: An organic electroluminescence device in which a polycyclic compound including an electron donor and an electron acceptor is included in an emission layer is provided. The electron donor contains an acridine derivative or a dibenzo-azasiline derivative, and the electron acceptor contains B as a ring-forming atom, O or S directly bonded to B, and a heterocyclic group in which three or five hexagonal rings are condensed. Accordingly, an organic electroluminescence device having high efficiency may be achieved.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: January 3, 2023
    Assignees: Samsung Display Co., Ltd., Kyushu University, National University Corporation
    Inventors: Yuuki Miyazaki, Yoshimasa Fujita, Kyohei Matsuo, Takuma Yasuda
  • Patent number: 11499178
    Abstract: Provided is a labeling method for nucleic acid including a reaction step for hybridizing a nucleic acid probe that has a nucleotide sequence complementary to that of a nucleic acid to be labeled and contains a reactive nucleobase derivative incorporated at a position complementary to that of a target nucleobase as a target of labeling in the nucleic acid to be labeled, to the nucleic acid to be labeled; a transferring step for transferring a transfer group contained in the reactive nucleobase derivative to the nucleotide residue containing the target nucleobase in the nucleic acid to be labeled; and a labeling step for labeling the transfer group transferred to the nucleotide residue with a radioactive material.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: November 15, 2022
    Assignees: Kyushu University, National University Corporation, Kurume Research Park Co., Ltd.
    Inventors: Shigeki Sasaki, Yosuke Taniguchi, Gakuro Harada
  • Publication number: 20220313639
    Abstract: The object of the present invention is to provide a pharmaceutical agent which activate mitochondrial function, particularly, an inexpensive pharmaceutical agent. The problem can be solved by a mitochondrial function activator of the present invention, comprising ?-alanine or glycine, or a salt thereof.
    Type: Application
    Filed: June 16, 2020
    Publication date: October 6, 2022
    Applicants: Yuki Gosei Kogyo Co., Ltd., Kyushu University, National University Corporation
    Inventors: Tetsuji NODA, Tomotsune ONAGA, Yoshinori KATAKURA
  • Publication number: 20220183690
    Abstract: An object of the present invention is to provide a means for fixing a pancreatic resection stump created during an operation for resecting a portion of the pancreas. The present invention provides a polymeric surgical clip characterized in that the clip comprises a first arm portion, a second arm portion, and a resilient hinge portion joining the first and second arm portions together, both the arm portions are joined to the resilient hinge portion at their bases, the first arm portion has a convex outer surface and a concave inner surface clamping the pancreas, the second arm portion has a convex or flat outer surface and a concave or flat inner surface clamping the pancreas, the first arm portion forms at its distal end a deflectable hook portion curved toward the second arm portion, and the clip is configured so that, in a closed position, a distal end of the second arm portion enters inside the curved hook portion and engages with the hook portion to lock the clip in the closed position.
    Type: Application
    Filed: March 17, 2020
    Publication date: June 16, 2022
    Applicants: National University Corporation Kumamoto University, Kyushu University, National University Corporation
    Inventors: Hideo Baba, Yoichi Yamashita, Ijima Hiroyuki
  • Patent number: 11279680
    Abstract: Provided are: a dicyano N-heterocyclic compound represented by formula (I) (in the formula, R3 represents an electron-donating group, and n represents the number of repetitions of the content in brackets and is 0 or 1), the compound having exceptional heat resistance and light emission characteristics; a light-emitting material; and a light-emitting element in which the same is used.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: March 22, 2022
    Assignees: Kyushu University, National University Corporation, Nippon Soda Co., Ltd.
    Inventors: Takuma Yasuda, Ryuhei Furue, Hiroyuki Ishihara, Yukio Fukushima
  • Publication number: 20210393963
    Abstract: A blood pressure controlling apparatus includes an acquiring part configured to acquire biological information indicating blood pressure of a subject, a producing part configured to produce a frequency modulated pulse train on the basis of the biological information, and a supplying part configured to supply an electrical current on the basis of the frequency modulated pulse train, to an electrode attached on the subject. The electrical current stimulates baroreceptor afferent nerves of the subject.
    Type: Application
    Filed: November 1, 2019
    Publication date: December 23, 2021
    Applicant: Kyushu University, National University Corporation
    Inventors: Keita Saku, Kenji Sunagawa, Takeshi Tohyama, Kazuya Hosokawa, Takafumi Sakamoto
  • Patent number: 11110594
    Abstract: A fine work assistance system is configured such that a parallel link mechanism is used for a slave manipulator activated by a master operation, and a precise motion for microsurgery or the like is performed by remote control. In a slave unit of a master-slave manipulator, the parallel link mechanism with multiple degrees of freedom is used for a link mechanism in which an end effector is movable with respect to a base. Moreover, a tip operation part is driving by a hydraulic driving mechanism such that a plurality of linear actuators supported by the base move one ends of links so as to move the end effector, and the slave unit is activated in response to a user operation on the master unit. This achieves the precise motion of the end effector and causes the end effector to perform operations for a precise work.
    Type: Grant
    Filed: November 1, 2016
    Date of Patent: September 7, 2021
    Assignee: Kyushu University, National University Corp.
    Inventors: Susumu Oguri, Makoto Hashizume, Masaharu Murata