Patents Assigned to Kyushu University
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Publication number: 20210393963Abstract: A blood pressure controlling apparatus includes an acquiring part configured to acquire biological information indicating blood pressure of a subject, a producing part configured to produce a frequency modulated pulse train on the basis of the biological information, and a supplying part configured to supply an electrical current on the basis of the frequency modulated pulse train, to an electrode attached on the subject. The electrical current stimulates baroreceptor afferent nerves of the subject.Type: ApplicationFiled: November 1, 2019Publication date: December 23, 2021Applicant: Kyushu University, National University CorporationInventors: Keita Saku, Kenji Sunagawa, Takeshi Tohyama, Kazuya Hosokawa, Takafumi Sakamoto
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Patent number: 11110594Abstract: A fine work assistance system is configured such that a parallel link mechanism is used for a slave manipulator activated by a master operation, and a precise motion for microsurgery or the like is performed by remote control. In a slave unit of a master-slave manipulator, the parallel link mechanism with multiple degrees of freedom is used for a link mechanism in which an end effector is movable with respect to a base. Moreover, a tip operation part is driving by a hydraulic driving mechanism such that a plurality of linear actuators supported by the base move one ends of links so as to move the end effector, and the slave unit is activated in response to a user operation on the master unit. This achieves the precise motion of the end effector and causes the end effector to perform operations for a precise work.Type: GrantFiled: November 1, 2016Date of Patent: September 7, 2021Assignee: Kyushu University, National University Corp.Inventors: Susumu Oguri, Makoto Hashizume, Masaharu Murata
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Publication number: 20210267886Abstract: A gel-in-oil emulsion comprising a gelled water-soluble polymer, an oil, and a surfactant, and a transdermal absorption preparation comprising the gel-in-oil emulsion.Type: ApplicationFiled: June 27, 2019Publication date: September 2, 2021Applicants: Nippon Shokubai Co., Ltd., Kyushu University, National University CorporationInventors: Hiroyuki Ijima, Nana Shirakigawa, Emiko Yamamoto
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Publication number: 20210062154Abstract: The present disclosure provides a culture substrate for culturing stem cells, the culture substrate including a surface portion having: soft regions that extend side by side along a plurality of directions intersecting each other; and a plurality of stiff regions compartmented by the soft regions, wherein in the surface portion, the stiff regions have acute angle parts protruding toward the soft regions, and the cells can be deformed into a shape that is accommodated within the region of the stiff regions.Type: ApplicationFiled: March 11, 2019Publication date: March 4, 2021Applicant: Kyushu University, National University CorporationInventors: Satoru Kidoaki, Kousuke Moriyama, Hiroyuki Ebata
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Patent number: 10830768Abstract: In an aspect, a sensor includes a combining portion 240 that combines with a second substance 220 having a molecular weight larger than a molecular weight of a first substance 210. Further, in an aspect, the sensor includes a substrate 10 including a surface on which the combining portion 240 is disposed, the combining portion 240 detecting whether or not the first substance 210 is included in an analyte that has come into contact with both an aptamer 230 including a first combining part 231 for the first substance 210 and a second combining part 232 for the second substance 220 and being combined with either of the first substance 210 and the second substance 220 and the second substance 220.Type: GrantFiled: June 12, 2018Date of Patent: November 10, 2020Assignees: Kyushu University, National University Corporation, KYOCERA CorporationInventors: Shinsuke Sando, Hideharu Kurioka
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Publication number: 20200343453Abstract: A compound having two or more donor groups differing in the structure and a linking group that links these donor groups, wherein the linking group is an aromatic group composed of one or more benzene rings optionally substituted with an alkyl group or a halogeno group, has good light-emitting characteristics.Type: ApplicationFiled: March 10, 2017Publication date: October 29, 2020Applicants: Kyushu University, University Corporation, Hodogaya Chemical Co., Ltd.Inventors: Youichi TSUCHIYA, Yan GENG, Hin Wai MO, Chihaya ADACHI, Takehiro TAKAHASHI
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Patent number: 10813655Abstract: A manipulator includes a flexible actuating body, that includes a rectangular horizontal plate spring, a curved vertical plate spring which stands upright having a plate surface perpendicular to a plate surface of the horizontal plate spring, of which a base end is connected to one end of the horizontal plate spring in a longitudinal direction, which protrudes to one side in a width direction of the horizontal plate spring, which extends along the longitudinal direction of the horizontal plate spring, and of which a tip end in the extending direction is a portion bent in a direction opposite to the protruding direction, a shaft body which is connected to a tip end of the bent portion, and is rotatably supported at a center perpendicular to the plate surface of the horizontal plate spring, and an actuator protruding in a radius direction from an outer circumference of the shaft body.Type: GrantFiled: September 30, 2016Date of Patent: October 27, 2020Assignee: Kyushu University, National University CorporationInventors: Jumpei Arata, Makoto Hashizume, Susumu Oguri
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Patent number: 10797242Abstract: An organic compound having an excellent electron injection and transport performance is provided as a material for a low-power-consumption organic electroluminescent device. A low-power-consumption organic electroluminescent device is also provided by using the compound. The compound is a compound of general formula (1) or (2) having a substituted bipyridyl and triphenylene ring structure. The organic electroluminescent device includes a pair of electrodes, and one or more organic layers sandwiched between the pair of electrodes, and uses the compound as constituent material of at least one of the organic layers.Type: GrantFiled: May 24, 2017Date of Patent: October 6, 2020Assignees: Hodogaya Chemical Co., Ltd., Kyushu University, National University CorporationInventors: Chihaya Adachi, Kazunori Togashi, Norimasa Yokoyama, Shintaro Nomura
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Patent number: 10731198Abstract: A sensor determines whether a specimen includes a first substance. In an exemplary embodiment, the sensor includes a base. In an exemplary embodiment, the sensor is configured to determine whether the specimen includes the first substance and further includes, on the base, a detection unit on which a second substance is immobilized. The second substance includes a bond that is cleft by the reaction with hydrogen peroxide. In an exemplary embodiment, the specimen that is brought in contact with an enzyme that generates the hydrogen peroxide by the reaction with the first substance is introduced to the detection unit in the sensor configured to determine whether the specimen includes the first substance.Type: GrantFiled: June 26, 2013Date of Patent: August 4, 2020Assignees: KYOCERA Corporation, Kyushu University, National University CorporationInventors: Hideharu Kurioka, Shinsuke Sando
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Patent number: 10714693Abstract: A polycyclic compound and an organic electroluminescence device including the same. The polycyclic compound according to an example embodiment is represented by the following Formula 1. wherein in Formula 1, Cy1 is carbonyl-containing five- or six-membered and substituted or unsubstituted cyclic hydrocarbon or substituted or unsubstituted heterocycle, and R1 to R4 are each independently a hydrogen atom or a group represented by the following Formula 2 or 3.Type: GrantFiled: March 30, 2017Date of Patent: July 14, 2020Assignees: Samsung Display Co., Ltd., Kyushu University, National University CorporationInventors: Hiromi Nakano, Shuri Sato, Yoshimasa Fujita, Nobutaka Akashi, Takuma Yasuda, JiYoung Lee
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Patent number: 10702352Abstract: An operating portion which allows a bending treatment instrument to be inserted into an endoscope channel and bendably operated smoothly through intuition. The operating portion is connected with a device wire and bending wires and used to operate the treatment instrument and bend a freely bendable, bending treatment instrument, where the device wire is connected to a treatment instrument provided at a distal end of the bending treatment instrument and is used to operate the treatment instrument and the plurality of bending wires is used to bend the bending treatment instrument, the operating portion including: an operating portion body; a guide unit penetrated by the device wire; a bending wire pulling unit connected with the bending wires and swingably assembled onto the guide unit; and a grip portion connected with the device wire and configured to be reciprocable in an axial direction of the bending wire pulling unit.Type: GrantFiled: April 15, 2015Date of Patent: July 7, 2020Assignees: Kyushu University, National University Corporation, HOGY MEDICAL CO., LTD.Inventors: Ryu Nakadate, Hajime Kenmotsu, Makoto Hashizume, Hiroyasu Fujita, Shunsuke Nagai, Jiro Kato
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Patent number: 10695714Abstract: A system for producing an ion concentration gradient and a temperature-responsive electrolyte material which are utilizable, for example, for efficiently converting heat energy that has been discarded into reusable energy or for efficiently recovering an acid gas, such as carbon dioxide is provided. A temperature-responsive electrolyte is used to produce an ion concentration gradient by means of a temperature gradient. The temperature-responsive electrolyte is used in the state of an aqueous solution and also in the state of a solid phase.Type: GrantFiled: April 16, 2019Date of Patent: June 30, 2020Assignee: Kyushu University, National University CorporationInventors: Yu Hoshino, Yoshiko Miura, Mengchen Yue, Kazushi Imamura
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Patent number: 10686139Abstract: A nitrogen-containing compound and an organic electroluminescence device including the same, the nitrogen-containing compound being represented by the following Formula 1:Type: GrantFiled: December 14, 2016Date of Patent: June 16, 2020Assignees: Samsung Display Co., Ltd., Kyushu University, National University CorporationInventors: Hiromi Nakano, Shuri Sato, Yoshimasa Fujita, Nobutaka Akashi, Takuma Yasuda, Inseob Park
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Patent number: 10629438Abstract: The laser doping apparatus may irradiate a predetermined region of a semiconductor material with a pulse laser beam to perform doping. The laser doping apparatus may include: a solution supplying system configured to supply dopant-containing solution to the predetermined region, and a laser system including at least one laser device configured to output the pulse laser beam to be transmitted by the dopant-containing solution, and a time-domain pulse waveform changing apparatus configured to control a time-domain pulse waveform of the pulse laser beam.Type: GrantFiled: April 24, 2019Date of Patent: April 21, 2020Assignees: Kyushu University, Gigaphoton Inc.Inventors: Tomoyuki Ohkubo, Hiroshi Ikenoue, Akihiro Ikeda, Tanemasa Asano, Osamu Wakabayashi
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Publication number: 20200103423Abstract: Disclosed is a method for obtaining information on subject's diabetes, comprising measuring lipoprotein's ability to uptake sterol in a biological sample of a subject, wherein a measured value of ability to uptake sterol per unit volume of the biological sample is an indicator of diabetes onset risk.Type: ApplicationFiled: September 25, 2019Publication date: April 2, 2020Applicants: Kyushu University, National University Corporation, NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, SYSMEX CORPORATIONInventors: Toshiharu NINOMIYA, Yoichiro HIRAKAWA, Ryuji TOH, Yasuhiro IRINO, Katsuhiro MURAKAMI, Keiko MIWA, Amane HARADA
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Publication number: 20200064262Abstract: A first aspect of the present invention is an optical member that blocks straight traveling of light of a second wavelength rather than straight traveling of light of a first wavelength, and is provided with a silicone resin part, and optical material particles dispersed in the silicone resin part, wherein the refractive indexes of the silicone resin part and the optical material particles match at the first wavelength, and do not match at the second wavelength. Consequently, it becomes possible to provide an optical member or the like that selectively transmit a specific wavelength (the first wavelength) by a member different from those of conventional optical elements.Type: ApplicationFiled: November 30, 2017Publication date: February 27, 2020Applicants: Kyushu University, National University Corporation, Ushio Denki Kabushiki KaishaInventors: Yuji OKI, Kinichi MORITA, Hiroyuki OHASHI
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Patent number: 10550181Abstract: Disclosed are an anti-human TIM-3 antibody having high ADCC activity or antibody fragment thereof by screening a monoclonal antibody or antibody fragment thereof which binds to the amino acid sequence of the extracellular region of TIM-3 or its three-dimensional structure and exhibits ADCC activity; a hybridoma which produces the antibody; a DNA encoding the antibody; a vector comprising the DNA; a transformant which is obtainable by introducing the vector; a method for producing the antibody or the antibody fragment thereof which comprises using the hybridoma or the transformant; and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment thereof as an active ingredient.Type: GrantFiled: December 9, 2016Date of Patent: February 4, 2020Assignees: KYOWA KIRIN CO., LTD, Kyushu University, National University CorporationInventors: Shin-ichiro Takayanagi, Hitomi Tomura, Tomonori Tawara, Yoshimasa Inagaki, Tsuguo Kubota, Koichi Akashi, Yoshikane Kikushige
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Patent number: 10509033Abstract: Provided are a method for diagnosing chronic inflammatory demyelinating polyneuropathy (CIDP), in particular, a diagnostic method for specifically diagnosing a group having a specific pathophysiology among CIDPs, and a kit and a biomarker for use in such a diagnosis. The diagnostic method for diagnosing CIDP of the present invention includes a step of measuring an anti-neurofascin 155 antibody contained in a sample.Type: GrantFiled: January 20, 2016Date of Patent: December 17, 2019Assignee: Kyushu University, National University CorporationInventors: Junichi Kira, Nobutoshi Kawamura, Ryo Yamasaki, Dai Matsuse, Hidenori Ogata
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Publication number: 20190284546Abstract: A method for controlling the kinetics of a cultured cell includes: a culture step of culturing a cell adhered to the surface of a base material including titanium oxide having an anatase structure on the surface; an irradiation step of irradiating the surface with light in a wavelength range in which the titanium oxide exhibits photocatalytic activity during culture of the cell; and a control step of controlling the kinetics of the cell by controlling the irradiation amount of the light to the surface. The wavelength range may be 400 nm or less.Type: ApplicationFiled: November 14, 2017Publication date: September 19, 2019Applicants: National University Corporation Kumamoto University, Ushio Denki Kabushiki Kaisha, Kyushu University, National University CorporationInventors: Yuta NAKASHIMA, Kinichi MORITA, Kosuke TASHIRO
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Patent number: RE47723Abstract: Provided is an angle detection device capable of detecting the angle with high sensitivity by a very simple assembly process without requiring complicated processing. The angle detection device is provided with: a rotor (5) which is formed by a disk plate body produced from a magnetic substance having uniaxial magnetic anisotropy, the disk plate body rotating around a center point within the disk plate surface; a stator (3) which is provided to face the plate surface of the disk plate body of the rotor (5), has approximately the same external shape as that of the rotor, and is divided into a plurality of fan-shaped regions, and in which an exciting coil or a detection coil is wound along the outer periphery of each of the divided regions.Type: GrantFiled: September 14, 2017Date of Patent: November 12, 2019Assignee: Kyushu University, National University CorporationInventor: Ichiro Sasada