Abstract: The present invention relates to the use of whole soft avocados to obtain an avocado oil rich in unsaponifiable, said unsaponifiable containing aliphatic acetogenins and/or their derivatives. Advantageously, the oil has an acid value less than or equal to 3 mgKOH/g. The invention also relates to a process for obtaining an avocado oil rich in unsaponifiable from whole soft avocados. said unsaponifiable containing aliphatic acetogenins and/or their derivatives. The invention also relates to an avocado oil rich in unsaponifiable obtainable by this process. The invention also relates to the use of the avocado oil to prepare a concentrate of avocado oil enriched in unsaponifiable or an avocado unsaponifiable rich in aliphatic furans.
Abstract: The invention relates to a method for the extraction of all unsaponifiable fraction contained in a vegetable oil, an oil originating from a micro-organism or a vegetable butter or in a co-product from the vegetable oil refining industry, such as deodorization discharge. The method includes at least: A) a step comprising the transformation of the aforementioned oils, butter or co-product from the vegetable oil refining industry or oils originating from micro-organisms into a hydro-alcoholic solution by means of, in particular, a step selected from saponification and esterification steps; B) a step comprising the extraction of the hydro-alcoholic solution in which the fatty fraction is separated from the unsaponifiable fraction by means of liquid/liquid extraction; and C) an optional step comprising the purification of the unsaponifiable fraction, selected from the group containing crystallization and liquid/liquid extraction steps.
Type:
Grant
Filed:
January 31, 2011
Date of Patent:
February 17, 2015
Assignee:
Laboratoires Expanscience
Inventors:
Alex Saunois, Jacques Legrand, Eglantine Mercier
Abstract: The present invention relates to the use of avocado seeds in order to obtain avocado oil enriched in alkyl polyols and/or acetylated derivatives thereof, said avocado seeds accounting for 10 to 50% by weight relative to the total weight of avocado used. The invention also relates to a method for obtaining avocado oil enriched in alkyl polyols or acetylated derivatives thereof from at least avocado seeds, said avocado seeds accounting for 10 to 50% by weight relative to the total weight of avocado used. The invention also relates to avocado oil enriched in alkyl polyols and/or acetylated derivatives thereof, obtainable by the present method. The invention also relates to the use of avocado oil in order to prepare an avocado oil concentrate enriched in alkyl polyols and/or acetylated derivatives thereof, or to prepare an avocado unsaponifiable enriched in alkyl polyols.
Type:
Application
Filed:
January 14, 2013
Publication date:
November 27, 2014
Applicant:
Laboratoires Expanscience
Inventors:
Philippe Msika, Jacques Legrand, Sebastien Garnier
Abstract: The present invention relates to a composition including at least one C7 sugar, or derivative from esterification of said sugar, and a pharmaceutically acceptable carrier for treating alopecia. The present invention also relates to a method for cosmetically treating hair and nails, said method being intended to stimulate the growth thereof and/or slow the loss thereof. According to said method, a cosmetic composition including at least one C7 sugar, or derivative from esterification of said sugar, is administered. The present invention finally relates to a method for cosmetic care of hair and/or eyelashes and/or nails.
Abstract: The present application relates to a cosmetic method for preventing and/or treating skin redness, characterized in that a composition comprising arabinogalactan is administered to a person who may form or who is displaying redness. This cosmetic composition can be administered topically or orally.
Type:
Grant
Filed:
May 11, 2012
Date of Patent:
November 4, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Caroline Baudouin, Franck Menu
Abstract: The invention relates to using one or several synthetic or natural furan alkyls for preparing a drug for preventing and/or treating diabetes and insulin resistance, thereby preventing the risks of cardiovascular, nervous, cutaneous, renal, ocular and infectious diseases. The use of one or several synthetic or natural furan alkyls for cosmetically treating diabetes related skin disorders is also disclosed.
Type:
Grant
Filed:
May 27, 2005
Date of Patent:
October 14, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Antoine Piccirilli, Philippe Msika, Nathalie Piccardi
Abstract: The invention relates to a composition comprising a Vigna unguiculata seed extract. The composition is advantageously cosmetic, pharmaceutical, dermatological or nutraceutical. The invention further relates to a method for extracting a Vigna unguiculata seed extract, as well as to the resulting extract. The invention further relates to one such composition or one such extract for use in the prevention or treatment of disorders or pathologies of the skin, mucosae or appendages, for use in the prevention or treatment of vascular disorders, or for use in the prevention or treatment of adipose tissue alterations. Finally, the invention relates to a method for cosmetic care of the skin, appendages or mucosae, in order to improve the condition or appearance thereof, comprising the administration of one such composition or one such extract.
Type:
Grant
Filed:
November 30, 2010
Date of Patent:
September 23, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Alex Saunois, Sophie Leclere-Bienfait, Caroline Baudoin
Abstract: The invention relates to a method for the cosmetic prevention and/or treatment of stretch marks on the skin, characterised in that the method comprises administering a composition containing arabinogalactan as an active principle to a person that may develop or has stretch marks. Said cosmetic composition can be administered in a topical or oral manner.
Type:
Grant
Filed:
November 9, 2009
Date of Patent:
July 1, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Caroline Baudouin, Dalale Naaimi, Franck Menu
Abstract: The present invention relates to a cosmetic, nutraceutical or dermatological composition for treating or preventing acne, comprising a peptide and oside extract of Schizandra fruit and a suitable excipient. Preferably, the extract is obtained from Schizandra sphenanthera. The composition may also comprise at least one anti-acne agent selected from a sebum-regulating agent, an antibacterial and/or antifungal agent, a keratolytic agent and/or a keratoregulating agent, an astringent, an anti-inflammatory and/or anti-irritant, an antioxidant and/or a free-radical scavenger, a cicatrizing agent, an anti-ageing agent and a moisturizing agent. The invention also relates to a method for cosmetic treatment of acne, characterized in that a cosmetic composition according to the invention is applied to the affected areas of the skin, or in that the affected individual takes a nutraceutical composition according to the invention orally.
Abstract: The present invention relates to the use of a lupeol-rich extract for the production of a cosmetic or pharmaceutical composition for treating and/or preventing a connective tissue degeneration. Said invention also relates to the use of a lupeol-rich extract for the production of a pharmaceutical composition for preventing and/or treating non-inflammatory articular pathologies, periodontal diseases and stretch marks. The invention also relates to the use of a lupeol-rich extract for the production of a cosmetic composition as a cicatrizing agent, a restructuring agent and an anti-sagging agent for skin and/or mucosae.
Type:
Grant
Filed:
July 19, 2004
Date of Patent:
June 10, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Antoine Piccirilli, Nathalie Piccardi
Abstract: The invention relates to a composition comprising a lupin total extract consisting of a lupin sugar extract, comprising at least 50% galactooligosaccharides by weight, in relation to the weight of dry matter, and a lupin peptide extract. The composition can also contain a chromane derivative or a chromene derivative. The invention also relates to a pharmaceutical and/or cosmetic composition comprising said lupin total extract, used advantageously as an anti-inflammatory agent, which repairs the cutaneous barrier and heals, used particularly in the prevention and/or treatment of erythemas.
Type:
Grant
Filed:
April 4, 2005
Date of Patent:
May 27, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Jean-Christophe Choulot, Antoine Piccirilli, Nathalie Piccardi, Philippe Msika, François Paul
Abstract: The invention relates to the cosmetic use of at least one oxazolin as a depigmenting active ingredient in a depigmenting composition, and to the associated cosmetic treatment method. The invention also relates to the use of at least one oxazolin for preparing an active medicament as a depigmenting agent, and to a depigmenting cosmetic composition comprising at least one oxazolin as a depigmenting active ingredient.
Abstract: The invention concerns a composition containing at least an oxazolin, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an alkanolamide, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such composition on the skin and/or mucosa.
Type:
Grant
Filed:
January 13, 2009
Date of Patent:
February 18, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Nathalie Piccardi, Antoine Piccirilli
Abstract: The invention relates to a composition containing an extract of seeds of Acacia macrostachya. Advantageously the composition is cosmetic, pharmaceutical, dermatological or nutraceutical. The invention also relates to a method for extracting a Acacia macrostachya seed extract, as well as to the resulting extract. The invention further relates to one such composition or one such extract for use in the prevention or treatment of disorders and diseases affecting the skin, mucosae or appendages, for use in the prevention or treatment of vascular disorders and for use in the prevention or treatment of adipose tissue alterations. Moreover, the invention relates to a method for cosmetic care of the Skin, appendages and mucosae in order to improve the condition or appearance thereof, comprising the administration of one such composition or one such extract.
Type:
Grant
Filed:
November 30, 2010
Date of Patent:
February 4, 2014
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Alex Saunois, Sophie Leclere-Bienfait, Caroline Baudoin
Abstract: A cosmetic, dermatological or nutraceutical composition including a Schisandra sphenanthera fruit peptide and sugar extract, a crude oil, a refined oil, a refined oil concentrate, and/or the unsaponifiable fraction of the concentrate. A method for preparing a peptide and sugar extract, a refined oil, and/or a concentrate and an unsaponifiable fraction of oil of the Schisandra sphenanthera fruit.
Abstract: A method for reducing the formation of and/or treating skin stretchmarks is described. The method is characterized in that a composition is applied to the areas of skin liable to form or comprising stretchmarks, including skin of the thighs, abdomen, and/or breast. The applied composition includes a soya peptide, a tripeptide consisting of the amino acids glycine, histidine, and lysine, and/or mixtures of the soya peptide and tripeptide in a suitable application vehicle. The composition displays good skin tolerance.
Abstract: The invention relates to a drug or a dermatological composition containing an avocado peptide extract for treating and/or preventing pruritus, in particular gravidic pruritus, pruritus sine materia, pruritus in newborns, and pruritus originating from a drug.
Type:
Grant
Filed:
November 6, 2009
Date of Patent:
May 28, 2013
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Caroline Baudoin, Stéphanie Bredif
Abstract: The invention relates to a medicament which comprises a peptide extract of avocado and which can also comprise a composition containing D-mannoheptulose and/or perseitol, such as a water-soluble extract of avocado sugars, and/or a peptide extract of lupine. The inventive medicament is intended for the treatment and/or prevention of illnesses that are linked to an alteration in innate and/or acquired immunity, through an increase in the production of anti-microbial peptides, preferably hBD-2, without inducing inflammatory reactions, irritations or intolerances.
Type:
Grant
Filed:
October 8, 2010
Date of Patent:
January 8, 2013
Assignee:
Laboratoires Expanscience
Inventors:
Antoine Piccirilli, Nathalie Piccardi, Philippe Msika, François Paul, Stéphanie Bredif
Abstract: The invention concerns the use of at least a fatty ester for preparing a composition designed to inhibit 5?-reductase activity. Said use produces a remarkable inhibiting effect of 5?-reductase thereby providing a novel response for treating dermatological pathologies and/or disorders related to congenital or acquired exaggeration of 5?-reductase activity, in particular for treating prostatic hypertrophy, prostatic adenoma, acne, hyperseborrhea, alopecia and hirsutism. The invention also concerns cosmetic treatment methods, in particular for greasy skin, and the use of said fatty esters as additives in a food product for human and/or animal consumption.
Type:
Grant
Filed:
January 18, 2001
Date of Patent:
November 27, 2012
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Antoine Piccirilli, Jacques Legrand
Abstract: The invention concerns a composition containing at least an alkanolamide, optionally combined with at least a compound such as a metalloprotease inhibitor, a PKC inhibitor, an anti-inflammatory agent, a soothing agent, an immunosuppressor, an ion chelating agent, an oxazolin, an oxazolidinone and a carbamic acid derivative. The invention also concerns the use of such a composition as medicine, in particular its use for preventing or treating skin pathologies of allergic and/or inflammatory and/or irritative origin or resulting from a danger signal. The invention further concerns a method for cosmetic treatment of sensitive, irritated, intolerant, allergy-prone, ageing skin and/or mucosa exhibiting skin barrier disorder, or exhibiting non-pathological immunologic imbalance, which consists in applying such a composition on the skin and/or mucosa.
Type:
Grant
Filed:
April 27, 2006
Date of Patent:
November 6, 2012
Assignee:
Laboratoires Expanscience
Inventors:
Philippe Msika, Nathalie Piccardi, Antoine Piccirilli