Patents Assigned to Labsystems Oy
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Patent number: 6447729Abstract: An apparatus for separating magnetic particles from a solution includes a vessel with a smaller diameter lower portion and larger diameter upper portion, a magnetic remover and a positioner for the magnetic remover. The transition between the small and large diameter portions of the vessel facilitates separation of droplets from the magnetic remover as it is removed from the vessel, while still retaining magnetic particles.Type: GrantFiled: January 7, 2000Date of Patent: September 10, 2002Assignee: Labsystems OyInventor: Jukka Tuunanen
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Patent number: 6372504Abstract: Conveying of a sample disk method and apparatus for into a reaction vessel is described wherein the sample disk (11) is attached to a tooth (2), where the sample disk is further conveyed to the reaction vessel.Type: GrantFiled: September 24, 1999Date of Patent: April 16, 2002Assignee: Labsystems OyInventors: Jukka Tervamäki, Jukka Tuunanen, Jouko Mikkonen
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Patent number: 6207463Abstract: The invention relates to a means for separating magnetic particles from a composition. The means comprises an elongated protective cover (1) that comprises a recess (2) extending from the upper end towards the lower end thereof, the recess comprising a movable magnetic rod (4), the proportion of the length of the rod to its thickness being at least about 2:1. The invention can be used in different applications especially in the fields of biotechnology, biochemistry, and biomedicine. Collecting particles by using the means is easy and fast.Type: GrantFiled: June 3, 1997Date of Patent: March 27, 2001Assignee: Labsystems OyInventor: Jukka Tuunanen
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Patent number: 6197597Abstract: The invention concerns a solid-phase determination method and equipment and an adapter for use in these. In the method a sample is allowed to react with a separating reagent bound to the outer surface of a separate solid phase body, whereafter the body is removed from the vessel and is taken to a measurement vessel, if required through one or several intermediate step vessels. At least one vessel contains a medium needed in a determination step to be performed therein when the phase body is brought into this vessel. The invention is especially suitable for use in automatic immunodetermination systems.Type: GrantFiled: July 28, 1995Date of Patent: March 6, 2001Assignee: Labsystems OyInventor: Jukka Tuunanen
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Patent number: 6164449Abstract: A pipette tip refill pack has several layers of pipette tips stacked upside down in a telescopic fashion. From the pack, the tips can be dispensed to a tip rack which is positioned upside down on top of the topmost tip layer.Type: GrantFiled: June 21, 1999Date of Patent: December 26, 2000Assignee: Labsystems OyInventor: Arto Lahti
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Patent number: 6144455Abstract: A fluorometer has a partly transparent mirror through which excitation light is directed to the sample and via which emitted light from the sample is reflected. Thus a high sensitivity and, furthermore, as homogenous a measurement sensitivity distribution as possible within a vessel are achieved. Measuring can be carried out from either above or below. The device is applicable for use especially when the fluorometer has simultaneously a plurality of samples.Type: GrantFiled: March 20, 1998Date of Patent: November 7, 2000Assignee: Labsystems OyInventors: Jukka Tuunanen, Timo Karmeniemi
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Patent number: 6111636Abstract: The application relates to a device for measuring the optical density of samples arranged in strips on a plate. The device comprises a measurement head (3) moving strip by strip in relation to the plate, said measurement head (3) including a light source (4) and a detector (5). Outside the strips, there is provided a transparent spot (9) or a light-proof spot (10), at which the light source intensity or the background signal can be measured either before or after the strip measurement. By employing the single-channel device according to the invention, it is possible to achieve virtually the same speed level as with a multichannel device. However, the device of the invention can be made remarkably simpler. One single-channel device can also be used for measuring several different plates.Type: GrantFiled: February 22, 1999Date of Patent: August 29, 2000Assignee: Labsystems OyInventor: Jukka Tuunanen
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Patent number: 6084680Abstract: An optical analyzer measures light directed from a sample to the detector. The apparatus has an optics module which has a detector and optics for directing light emitted by the sample to the detector and which module can be positioned alternatively either so that the light is directed to the detector from above the sample or so that light is directed to the detector from below the sample. The invention is usable in particular in fluorometers and in luminometers.Type: GrantFiled: March 20, 1998Date of Patent: July 4, 2000Assignee: Labsystems OyInventors: Jukka Tuunanen, Matti Priha, Heikki Tupakka, Timo Karmeniemi
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Patent number: 6065605Abstract: In an embodiment, a separating member is introduced into the compound, the member comprising a separating surface, the particles are pulled from the compound, by using a magnetic field, to be adhered to a separating surface, the effect of the magnetic field is eliminated, and the particles (16) are collected thereafter from the separating surface. In this way, it is possible to collect particles effectively even from a large volume. It is also easy to transfer particles into a small volume. The invention can be employed in various applications, especially in the fields of biotechnology, biochemistry, and biomedicine.Type: GrantFiled: September 18, 1997Date of Patent: May 23, 2000Assignee: Labsystems OyInventors: Matti Korpela, Jukka Tuunanen
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Patent number: 6040192Abstract: A system and method for handling magnetic particles, as in an immunoassay. A remover having a magnetic body and covering sleeve is inserted in a vessel containing magnetic particles and a liquid. The remover is moved up and down with the particles adhered to agitate the liquid and improve adherence of the particles.Type: GrantFiled: August 26, 1997Date of Patent: March 21, 2000Assignee: Labsystems OyInventor: Jukka Tuunanen
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Patent number: 6020211Abstract: The invention relates to a method for separating magnetic particles from a composition in a vessel. In the method, particles are first concentrated on the wall of the vessel and collected from this area by using a separation means (1) to which the magnetic particles adhere. In this way, particles can be collected efficiently. The invention can be used in different applications especially in the fields of biotechnology, biochemistry, and biomedicine.Type: GrantFiled: June 3, 1997Date of Patent: February 1, 2000Assignee: Labsystems OYInventor: Jukka Tuunanen
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Patent number: 5993746Abstract: A holder for sample-holding plates has a retainer for pressing a plate placed in the holder both against the back wall and against a side wall. Thus a plate of a certain type will always settle in the same position in the holder. It is also possible to use in the holder plates of many sizes, which can be kept in place during handling owing to the retainer. The device is suitable for use in particular in assay methods in which samples to be assayed are handled on plates having a plurality of wells, for example in optical analyzers or other apparatuses.Type: GrantFiled: March 20, 1998Date of Patent: November 30, 1999Assignee: Labsystems OyInventors: Matti Priha, Heikki Tupakka
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Patent number: 5970806Abstract: The patent application discloses a multi-cylinder pipette (1). The pipette specifically comprises 16 4.5 mm spaced channels (5), being thus suitable for use with a plate comprising equally spaced 16.times.24 wells. The set of cylinders of the pipette has been assembled from separate elements. A set of cylinders composed of elements provides ease of manufacture. Moreover, the same element and other components can be assembled to provide various pipettes.Type: GrantFiled: November 7, 1997Date of Patent: October 26, 1999Assignee: Labsystems OYInventors: Juha Telimaa, Mauno Heinonen, Kari Jarvimaki, Jouko Mikkonen
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Patent number: 5879633Abstract: The object of the invention is a ratchet wheel pipette having a body and in it a cylinder (3) and a piston (12) and a filling and dispensing arrangement to draw liquid into the cylinder and to dispense it in smaller portions with the aid of the piston.Type: GrantFiled: April 15, 1997Date of Patent: March 9, 1999Assignee: Labsystems OyInventors: Jukka Tervamaki, Tapani Pullinen, Jouko Mikkonen, Kari Jarvimaki
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Patent number: 5804144Abstract: A piston pipette having pulling equipment for moving a piston upward and pushing equipment for moving the piston downward. The pushing equipment has a movable gripping device (5), which when moving downward is attached to the piston and transfers the piston downward, and a movable transfer device (4) extending below the gripping device. According to the structure a pipette is obtained which is gripped a pen-shape handle and with which liquid can be dosed to a desired place as exactly as possible.Type: GrantFiled: June 6, 1997Date of Patent: September 8, 1998Assignee: Labsystems OYInventor: Jukka Tervamaki
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Patent number: 5660797Abstract: A pipette receptacle, or tip, which is applied to the `jet` or aspirate/blow tube of the pipette proper, wherein the receptacle has a top end with integral sections of a material different from the of the main body of the receptacle. These sections of different material can include an outer collar, an inner collar, or an entire upper portion. A color coding can be included. Additionally, methods of making the receptacle is disclosed.Type: GrantFiled: May 3, 1995Date of Patent: August 26, 1997Assignee: Labsystems OyInventor: Kari Jarvimaki
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Patent number: 5647994Abstract: The invention concerns a method and apparatus for separating magnetic particles from a solution and transferring them into another solution. The apparatus includes a pipette container, a separation wall defining a separation chamber, and a magnet disposed at one of a first location adjacent an outer side of the separation wall and a second location within the separation chamber. The magnet is adapted to be brought into such a state that a magnetic field is applied to the solution so that the particles will gather onto one of an inner side of the separation wall when disposed in the first location, or on a collection surface of the magnet when disposed in the second location, or so that the magnetic field no longer keeps the magnetic particles on the separation wall or collection surface. The pipette container includes a suction cylinder for drawing the solution into and solution from the pipette container via a jet channel.Type: GrantFiled: June 20, 1994Date of Patent: July 15, 1997Assignee: Labsystems OyInventors: Jukka Tuunanen, Matti Korpela
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Patent number: 5474742Abstract: An apparatus for removing solid bodies from an array of reaction vessels includes a frame and a plurality of lifters, each lifter for holding a solid body disposed within a reaction vessel for removal therefrom. The lifters are mounted on the frame in an array corresponding to the array of reaction vessels such that the array of lifters is positionable within the array of vessels in a manner which permits placement of a solid body in each vessel on each lifter while the lifters are positioned in the vessels.Type: GrantFiled: February 23, 1995Date of Patent: December 12, 1995Assignee: Labsystems OyInventor: Tamara Tuuminen
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Patent number: 5470536Abstract: A cuvette matrix, having a row of attached cuvettes, from which it is possible to detach one cuvette to be placed in an opening in a stand. On the outer surface of each cuvette, at an angle from the longitudinal direction of the row of cuvettes, there is a holder member, which facilitates the cuvette to adhere to the sides of an opening. The holder member is moved into contact with the stand when the cuvette is turned in the opening.Type: GrantFiled: October 25, 1993Date of Patent: November 28, 1995Assignee: Labsystems OyInventor: Kari Jarvimaki
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Patent number: 5435197Abstract: A pipette provided with a tip remover, which pipette has a lever mechanism, in which the tip is pressed off the pipette. In this way, it has been possible to decrease the force needed for the loosening.Type: GrantFiled: April 19, 1993Date of Patent: July 25, 1995Assignee: Labsystems OyInventors: Juha Telimaa, Jukka Tervamaki