Patents Assigned to Laurus Labs Limited
  • Patent number: 11634431
    Abstract: The present invention relates to a process for purification of protected polycyclic carbamoylpyridone derivatives and its conversion to polycyclic carbamoylpyridone derivatives or its pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: July 11, 2019
    Date of Patent: April 25, 2023
    Assignee: Laurus Labs Limited
    Inventors: Srinivasan Sitaraman, Ravikanth Sribhashyam, Ravinder Paladi
  • Patent number: 11434196
    Abstract: The present invention relates to a process for preparation of 2-Amino-5-hydroxy propiophenone, a key intermediate for the synthesis of camptothecin analogs including 7-Ethyl-10-hydroxycamptothecin (SN-38).
    Type: Grant
    Filed: January 14, 2020
    Date of Patent: September 6, 2022
    Assignee: Laurus Labs Limited
    Inventors: Uma Maheswer Rao Vasireddi, Venkata Ramana Kintali, Jagadeeswara Rao Dadi, Raj Koti Katkuri, Sridhar Tummu
  • Patent number: 11427570
    Abstract: The present invention is relates to an improved process for the preparation of pazopanib or a pharmaceutically acceptable salts thereof. The present invention also relates to novel polymorphic Forms of pazopanib hydrochloride, and its intermediates thereof.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: August 30, 2022
    Assignee: Laurus Labs Limited
    Inventors: Satyanarayana Chava, Seeta Rama Anjaneyulu Gorantla, Venkata Sunil Kumar Indukuri, Sanjay Kumar Dehury, Nagaraju Mekala, Jahangeer Baba Shaik, Durga Prasad Kuchipudi
  • Patent number: 11427555
    Abstract: Shown and described are improved processes for the preparation of dapagliflozin of Formula I, or its solvates or co-crystals thereof and intermediates and their use in the preparation of dapagliflozin of Formula I or its solvates or co-crystals thereof.
    Type: Grant
    Filed: August 9, 2017
    Date of Patent: August 30, 2022
    Assignee: Laurus Labs Limited
    Inventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar Dehury, Madana Venkata Sudhakar Gutti, Krishna Murthy Thopudurthi
  • Patent number: 11414386
    Abstract: The present invention provides processes for the preparation of ivacaftor using novel intermediates and a process for its preparation.
    Type: Grant
    Filed: September 16, 2020
    Date of Patent: August 16, 2022
    Assignee: Laurus Labs Limited
    Inventors: Suresh Thatipally, Venkata Krishna Reddy, Venkata Lakshmi Narasimha Rao Dammalapati, Satyanarayana Chava
  • Patent number: 11345684
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 31, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Patent number: 11345685
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: May 31, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Patent number: 11318116
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: May 3, 2022
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Venkateswar Rao Challagonda, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi
  • Patent number: 11299477
    Abstract: The present invention is relates to an improved process for the preparation of pazopanib or a pharmaceutically acceptable salts thereof. The present invention also relates to novel polymorphic Forms of pazopanib hydrochloride, and its intermediates thereof.
    Type: Grant
    Filed: February 26, 2020
    Date of Patent: April 12, 2022
    Assignee: Laurus Labs Limited
    Inventors: Satyanarayana Chava, Seeta Rama Anjaneyulu Gorantla, Venkata Sunil Kumar Indukuri, Sanjay Kumar Dehury, Nagaraju Mekala, Jahangeer Baba Shaik, Durga Prasad Kuchipudi
  • Patent number: 11066368
    Abstract: The present invention relates to an improved process for the preparation of pure pirfenidone having a particular particle size distribution, a crystalline form of pirfenidone, and pharmaceutical compositions thereof, as well as methods for particle size reduction of pirfenidone, and methods for particle size reduction of pirfenidone by wet milling techniques using colloid mill, ultrasonicator, or high speed homogenizer devices.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: July 20, 2021
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Venkata Pramod Kumar Mandadapu, Venkata Sunil Kumar Indukuri, Satyanarayana Chava, Tirumala Rao Galla, Jagadeeswara Rao Dadi, Uma Maheswer Rao Vasireddi
  • Patent number: 11046676
    Abstract: The present invention relates to process for the preparation of Empagliflozin or its co-crystals, solvates and/or polymorphs thereof. The present invention also relates to novel intermediates used therein, and process for the preparation thereof. The present invention further relates to process for preparation of amorphous and crystalline form of Empagliflozin.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: June 29, 2021
    Assignee: Laurus Labs Limited
    Inventors: Uma Maheswar Rao Vasireddi, Sanjay Kumar Dehury, Nagaraju Mekala, Jahangeer Baba Shaik, Srinivas Lagadapati
  • Patent number: 11040961
    Abstract: The present invention provides solid forms of SGLT2 inhibitors, to processes for their preparation and their use in the purification of SGLT2 inhibitors and also provided pharmaceutical compositions comprising them and their use in therapy.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: June 22, 2021
    Assignee: Laurus Labs Limited
    Inventors: Kameswar Rao Chivukula, Ram Thaimattam, Veeranarayana Bandlamudi, Durga Visweswar Rao Padala, Narapa Reddy Gade, Nageswar Rao Regandla, Sivarami Reddy Yasam, Venkata Rama Krishna Murthy Moturu, Venkata Sunil Kumar Indukuri, Uma Maheswar Rao Vasireddi, Srihari Raju Kalidindi, Satyanarayana Chava
  • Publication number: 20200407323
    Abstract: The present invention provides processes for the preparation of ivacaftor using novel intermediates and a process for its preparation.
    Type: Application
    Filed: September 16, 2020
    Publication date: December 31, 2020
    Applicant: Laurus Labs Limited
    Inventors: Suresh Thatipally, Venkata Krishna Reddy, Venkata Lakshmi Narasimha Rao Dammalapati, Satyanarayana Chava
  • Patent number: 10857132
    Abstract: The present invention relates to stable amorphous form of sacubitril valsartan trisodium complex and its solid dispersion compounds, processes for their preparation and pharmaceutical composition comprising the same. The present invention also relates to an improved process for the preparation of sacubitril sodium and its use in the preparation of sacubitril valsartan trisodium complex.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: December 8, 2020
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Ram Thaimattam, Venkateswar Rao Challagonda, Sivarami Reddy Yasam, Pavan Kumar Seethamraju, Uma Maheswar Rao Vasireddi
  • Patent number: 10844048
    Abstract: The present invention generally relates to crystalline forms of Lumacaftor, processes for its preparation and pharmaceutical compositions thereof. The present invention also relates to an improved process for preparation of Lumacaftor.
    Type: Grant
    Filed: January 6, 2018
    Date of Patent: November 24, 2020
    Assignee: Laurus Labs Limited
    Inventors: Ravindra Babu Bollu, Prasanta Kumar Dalasingh, Sushmita Dwarampudi, Chandrahasa Reddy Annem, Uma Maheswer Rao Vasireddi
  • Patent number: 10836753
    Abstract: The present invention provides solid forms of SGLT2 inhibitors, to processes for their preparation and their use in the purification of SGLT2 inhibitors and also provided pharmaceutical compositions comprising them and their use in therapy.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: November 17, 2020
    Assignee: Laurus Labs Limited
    Inventors: Kameswar Rao Chivukula, Ram Thaimattam, Veeranarayana Bandlamudi, Durga Visweswar Rao Padala, Narapa Reddy Gade, Nageswar Rao Regandla, Sivarami Reddy Yasam, Venkata Rama Krishna Murthy Moturu, Venkata Sunil Kumar Indukuri, Uma Maheswar Rao Vasireddi, Srihari Raju Kalidindi, Satyanarayana Chava
  • Patent number: 10815202
    Abstract: The present invention provides processes for the preparation of ivacaftor using novel intermediates and a process for its preparation.
    Type: Grant
    Filed: July 24, 2019
    Date of Patent: October 27, 2020
    Assignee: Laurus Labs Limited
    Inventors: Suresh Thatipally, Venkata Krishna Reddy, Venkata Lakshmi Narasimha Rao Dammalapati, Satyanarayana Chava
  • Patent number: 10800809
    Abstract: The present invention relates to an improved process for the preparation of carfilzomib or a pharmaceutically acceptable salt thereof. The present invention also relates to a process for the preparation of amorphous form of carfilzomib.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: October 13, 2020
    Assignee: Laurus Labs Limited
    Inventors: Sanjay Kumar Dehury, Nagaraju Mekala, Jahangeer Baba Shaik, Srinivasa Rao Buddepu, Lakshmi Kanth Kola, Venkata Sunil Kumar Indukuri, Seeta Rama Anjaneyulu Gorantla, Satyanarayana Chava
  • Patent number: 10738038
    Abstract: The present invention provides solid forms of SGLT2 inhibitors, to processes for their preparation and their use in the purification of SGLT2 inhibitors and also provided pharmaceutical compositions comprising them and their use in therapy.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: August 11, 2020
    Assignee: Laurus Labs Limited
    Inventors: Kameswar Rao Chivukula, Ram Thaimattam, Veeranarayana Bandlamudi, Durga Visweswar Rao Padala, Narapa Reddy Gade, Nageswar Rao Regandla, Sivarami Reddy Yasam, Venkata Rama Krishna Murthy Moturu, Venkata Sunil Kumar Indukuri, Uma Maheswar Rao Vasireddi, Srihari Raju Kalidindi, Satyanarayana Chava
  • Patent number: 10730859
    Abstract: The present invention is relates to an improved process for the preparation of pazopanib or a pharmaceutically acceptable salts thereof. The present invention also relates to novel polymorphic Forms of pazopanib hydrochloride, and its intermediates thereof.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: August 4, 2020
    Assignee: Laurus Labs Limited
    Inventors: Satyanarayana Chava, Seeta Rama Anjaneyulu Gorantla, Venkata Sunil Kumar Indukuri, Sanjay Kumar Dehury, Nagaraju Mekala, Jahangeer Baba Shaik, Durga Prasad Kuchipudi