Patents Assigned to Lawrence Livermore National Security, LLC
  • Patent number: 11320432
    Abstract: Systems are described, based on a primary binding compound and a secondary binding compound used in combination with a support to detect a target in a sample. The systems includes at least one support structure, at least one small primary support portion containing at least one molecule covalently bound to a visual colloidal marker, a plurality of secondary support portions comprising secondary binding compounds that are covalently bound to the support portions and chemically active, at least one pH litmus indicator, at least one pH strip, a buffer for lateral flow on the porous membrane support that allows preservation and activity of binding compounds.
    Type: Grant
    Filed: August 15, 2017
    Date of Patent: May 3, 2022
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventor: Jane P. Bearinger
  • Patent number: 11322626
    Abstract: Devices, methods and techniques are disclosed for providing a multi-layer diode without voids between layers. In one example aspect, a multi-stack diode includes at least two Drift Step Recovery Diodes (DSRDs). Each DSRD comprises a first layer having a first type of dopant, a second layer forming a region with at least ten times lower concentration of dopants compared to the adjacent layers, and a third layer having a second type of dopant that is opposite to the first type of dopant. The first layer of a second DSRD is positioned on top of the third layer of first DSRD. The first layer of the second DSRD and the third layer of the first DSRD are degenerate to form a tunneling diode at an interface of the first DSRD and second DSRD, the tunneling diode demonstrating a linear current-voltage characteristic.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: May 3, 2022
    Assignees: Lawrence Livermore National Security, LLC, BAE Systems Land & Armaments L.P., The Government of the United States, as represented by the Secretary of the Army
    Inventors: Lars F. Voss, Adam M. Conway, Luis M. Hernandez, Mark S. Rader
  • Patent number: 11312067
    Abstract: An apparatus is disclosed for performing an additive manufacturing operation to form a structure by processing a photopolymer resist material. The apparatus may incorporate a laser for generating a laser beam, and a tunable mask for receiving the laser beam which has an optically dispersive element. The mask splits the laser beam into a plurality of emergent beams each having a subplurality of beamlets of varying or identical intensity, with each beamlet emerging from a unique subsection of illuminated regions of the mask. A collimator collimates at least one of the emergent beams to form a collimated beam. One or more focusing elements focuses the collimated beam into a focused beam which is projected as a focused image plane on or within the resist material. The focused beam simultaneously illuminates a layer of the resist material to process an entire layer in a parallel fashion.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: April 26, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Sourabh Kumar Saha, Robert Matthew Panas, Shih-Chi Chen
  • Patent number: 11305252
    Abstract: An ultra low density film and an ultra low density solid material are produced by the steps of providing a vessel, introducing two immiscible fluids into the vessel, adding nanocrystals to at least one of the two immiscible fluids, applying a shear force to the two immiscible fluids and the nanocrystals in a manner that causes the nanocrystals to self-assemble and form colloidosomes. The colloidosomes amass and evaporation of the two fluids produces dried colloidosomes. The ultra low density self-assembled colloidosomes are hollow self-assembled colloidosomes, which are formed into the ultra-low density film and the ultra-low density solid.
    Type: Grant
    Filed: October 24, 2018
    Date of Patent: April 19, 2022
    Assignees: Lawrence Livermore National Security, LLC, Carnegie Mellon University
    Inventors: Christine A Orme, Sarah Baker, Yixuan Yu, Shelley L Anna, Charles Sharkey
  • Patent number: 11306653
    Abstract: The present disclosure relates to a system for controlling ignition of an intake charge directed into an internal combustion engine. The system may have a movable component operably associated with at least one of a piston of the engine or a combustion chamber of the engine. The movable component may be tuned to deflect in response to a predetermined pressure being reached in a cylinder in which the piston is housed. The movable component operates to deflect in response to the predetermined pressure being reached in the cylinder as the piston travels toward top dead center during its compression stroke, to change a compression ratio of the engine.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: April 19, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Nicholas Killingsworth, Daniel L. Flowers, Russell A. Whitesides
  • Patent number: 11309670
    Abstract: An electro-optical interface system is disclosed which incorporates a housing, an electrical circuit supported from the housing and configured to interface to a plurality of remote electrical components, an electronics subsystem and an optical subsystem. The electronics subsystem is housed within the housing and in communication with the electrical circuit. The optical subsystem is housed within the housing and in communication with the electronics subsystem. The optical subsystem receives electrical signals from the electronics subsystem which are representative of electrical signals received from the remote electrical components, and converts the received electrical signals into optical signals for transmission to a remote subsystem.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: April 19, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Susant Patra, Razi-Ul Muhammad Haque, Komal Kampasi
  • Patent number: 11309574
    Abstract: The present disclosure relates to an electrical energy storage apparatus which forms an interpenetrating, three dimensional structure. The structure may have a first non-planar channel filled with an anode material to form an anode, and a second non-planar channel adjacent the first non-planar channel filled with a cathode material to form a cathode. A third non-planar channel may be formed adjacent the first and second non-planar channels and filled with an electrolyte. The first, second and third channels are formed so as to be interpenetrating and form a spatially dense, three dimensional structure. A first current collector is in communication with the first non-planar channel and forms a first electrode, while a second current collector is in communication with the second non-planar channel and forms a second electrode. A separator layers separates the current collectors.
    Type: Grant
    Filed: November 20, 2015
    Date of Patent: April 19, 2022
    Assignees: Lawrence Livermore National Security, LLC, Board of Regents, The University of Texas System
    Inventors: Eric Duoss, Juergen Biener, Patrick Campbell, Julie A. Jackson, Geoffrey M. Oxberry, Christopher Spadaccini, Michael Stadermann, Cheng Zhu, Bradley Trembacki, Jayathi Murthy, Matthew Merrill
  • Patent number: 11305226
    Abstract: A composite material for gas capture including CO2 capture and capture of other gases. The composite material includes solid or liquid reactive material, filler material, and a gas-permeable polymer coating such that the reactive material forms micron-scale domains in the filler material.
    Type: Grant
    Filed: April 15, 2019
    Date of Patent: April 19, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Du T. Nguyen, Sarah E. Baker, William L. Bourcier, Joshuah K. Stolaroff, Congwang Ye, Maxwell R. Murialdo, Maira R. Cerón Hernández, Jennifer M. Knipe
  • Publication number: 20220113674
    Abstract: Differential Holography technology measures the amplitude and/or phase of, e.g., an incident linearly polarized spatially coherent quasi-monochromatic optical field by optically computing the first derivative of the field and linearly mapping it to an irradiance signal detectable by an image sensor. This information recorded on the image sensor is then recovered by a simple algorithm. In some embodiments, an input field is split into two or more beams to independently compute the horizontal and vertical derivatives using amplitude gradient filters in orthogonal orientations) for detection on one image sensor in separate regions of interest (ROIs) or on multiple image sensors. A third unfiltered beam recorded in a third ROI directly measures amplitude variations in the input field to numerically remove its contribution as noise before recovering the original wavefront using a numerical in algorithm.
    Type: Application
    Filed: November 24, 2021
    Publication date: April 14, 2022
    Applicant: Lawrence Livermore National Security, LLC
    Inventor: Frank RAVIZZA
  • Patent number: 11299816
    Abstract: A product according to one embodiment includes a first layer having a first composition, a first microstructure, and a first density; and a second layer above the first layer, the second layer having: a second composition, a second microstructure, and/or a second density. A gradient in composition, microstructure, and/or density exists between the first layer and the second layer, and either or both of the first layer and the second layer comprise non-spherical particles aligned along a longitudinal axis thereof.
    Type: Grant
    Filed: November 13, 2019
    Date of Patent: April 12, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Klint A. Rose, Joshua D. Kuntz, Marcus A. Worsley
  • Patent number: 11300572
    Abstract: Provided herein are methods and systems for the production of a nanolipoprotein particle (NLP) that includes a scaffold protein a membrane forming lipid and optionally a target protein. At least one of the scaffold protein and target protein can be provided through an IVT system. The membrane forming lipid, scaffold protein and optionally the target protein can be assembled for a time and under conditions that allow obtaining high yield NLPs, NPLs with an increased solubility, an NLP of a controlled size, and/or an NLP having a size predetermined to include a pre-selected target protein.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: April 12, 2022
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Matthew A. Coleman, Paul D. Hoeprich, Brent W. Segelke
  • Patent number: 11291203
    Abstract: A product includes a metallogel material having metal ions dispersed in an assembly having an organic compound. A method includes combining a metal salt, an organic compound precursor, and a glyme for forming a metallogel material having metal ions dispersed in an assembly having an organic compound.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: April 5, 2022
    Assignees: Lawrence Livermore National Security, LLC, Colorado State University Research Foundation
    Inventors: William Compel, Keith Morrison, James Armstrong, Christopher J. Ackerson
  • Patent number: 11296478
    Abstract: Techniques are provided for scaling the average power of high-energy solid-state lasers to high values of average output power while maintaining high efficiency. An exemplary technique combines a gas-cooled-slab amplifier architecture with a pattern of amplifier pumping and extraction in which pumping is continuous and in which only a small fraction of the energy stored in the amplifier is extracted on any one pulse. Efficient operation is achieved by propagating many pulses through the amplifier during each period equal to the fluorescence decay time of the gain medium, so that the preponderance of the energy cycled through the upper laser level decays through extraction by the amplified pulses rather than through fluorescence decay.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: April 5, 2022
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Alvin C Erlandson, Andrew J Bayramian, Constantin L Haefner, Craig W Siders, Thomas C Galvin, Thomas M Spinka
  • Patent number: 11294103
    Abstract: A method and system is disclosed for creating an optical component having a spatially controlled refractive index and uniform anti-reflective layer. The method may involve alternately depositing and dewetting two or more thin metal material layers on the substrate to form a mask having a spatially varying nano-particle distribution, and with an increased thickness beyond what could be achieved using a single, thick layer of the same material. The substrate may then be etched, using the mask, to imprint a spatially patterned nanostructure pattern on a surface the substrate in accordance with the mask.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: April 5, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Eyal Feigenbaum, Nathan James Ray, Jae Hyuck Yoo
  • Patent number: 11285165
    Abstract: This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity.
    Type: Grant
    Filed: April 8, 2020
    Date of Patent: March 29, 2022
    Assignees: Lawrence Livermore National Security, LLC, The Regents of the University of California
    Inventors: Sally J. DeNardo, Gerald L. DeNardo, Rodney L. Balhorn
  • Patent number: 11285704
    Abstract: According to one embodiment, a product includes a composite film comprising a polymer layer directly adjacent a graphene layer. According to another embodiment, a process includes layering a graphene layer onto a polymer layer to form a composite film.
    Type: Grant
    Filed: September 7, 2017
    Date of Patent: March 29, 2022
    Assignee: Lawrence Livermore National Security, LLC.
    Inventors: Michael Stadermann, Patrick Campbell, Philip E. Miller, Chantel Aracne-Ruddle, Sung Ho Kim, Francisco J. Espinosa-Loza
  • Patent number: 11279749
    Abstract: Synthetic apolipoproteins based on native/naturally occurring homolog proteins can be prepared using solid-phase peptide synthesis approaches combined with native chemical ligation methods to create analogs of full length apolipoproteins. The chemical synthesis is expected to allow introduction of non-natural amino acids, e.g., ?,??-dialkyl amino acids, with a periodicity that encourages both helix formation and amphipathicity. Such apolipoprotein analogs are expected to encourage, in some embodiments, facile and more complete NLP formation, enabling consideration of full spectrum of nanoparticle-based biotechnology applications ranging from therapeutic sequestration and delivery to energy/biofuel production to biopolymer production.
    Type: Grant
    Filed: September 9, 2016
    Date of Patent: March 22, 2022
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Paul D. Hoeprich, Jr., Julio A. Camarero
  • Patent number: 11271747
    Abstract: Systems and methods performed for generating authentication information for an image using optical computing are provided. When a user takes a photo of an object, an optical authentication system receives light reflected and/or emitted from the object. The system also receives a random key from an authentication server. The system converts the received light to plenoptic data and uploads it to the authentication server. In addition, the system generates an optical hash of the received light using the random key, converts the generated optical hash to a digital optical hash, and uploads the digital optical hash to the authentication server. When the authentication server receives the upload, it verifies whether the time of the upload is within a certain threshold time from the sending of the random key and whether the digital optical hash was generated from the same light as the plenoptic data.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: March 8, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Maxwell R. Murialdo, Brian Giera, Brian M. Howell, Robert M. Panas
  • Patent number: 11269137
    Abstract: A non-radial array of microstructure elements provides enhanced wavelength selective filtering. The elements are arranged along a line that does not intersect the center of the core. In this configuration, the first coupling element in an array that is nearest to the core is a non-integer array unit spacing from the main waveguide where the array unit spacing is defined as the flat to flat distance of a hexagonal cell.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: March 8, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Leily S. Kiani, Jay W. Dawson, Derrek R. Drachenberg, Michael J. Messerly, Paul H. Pax
  • Patent number: 11262514
    Abstract: The present disclosure relates to a hybrid opto-electrical module apparatus. The apparatus may have a module substrate having a plurality of electrically conductive circuit traces for carrying electrical signals, and at least one waveguide element for carrying optical signals. A waveguide substrate is in optical communication with the waveguide element. A transducer is supported on the waveguide substrate and in electrical communication with the circuit traces. The waveguide substrate has at least one three dimensional (3D) waveguide formed within its interior volume for routing optical signals between the waveguide element and the transducer. A first optical wirebond interfaces the waveguide element to the 3D waveguide, and a second optical wirebond interfaces the 3D waveguide to the transducer.
    Type: Grant
    Filed: December 9, 2019
    Date of Patent: March 1, 2022
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Susant Patra, Razi-Ul Muhammad Haque, Komal Kampasi, Ian Seth Ladner