Abstract: The present invention relates to a coded zoom knob (3) for detecting the rotation of the zoom drive shaft (4) of a zoom system (10) of a microscope (1), comprising a magnet (34) coupled to the zoom drive shaft (4), and a magnetic sensor (43) rotatably decoupled from the magnet (34) for sensing a rotation of the magnet (34).

Abstract: The invention relates to an apparatus (1) and method for automatically determining the blood flow direction (42) in a blood vessel (14) using the fluorescence light from a fluorophore (16). Blood flow direction (42) is determined by first identifying a blood vessel structure (38) in an input frame (6) from a camera assembly (2) using a pattern recognition module (26). Blood flow direction (42) is determined from the spatial gradient (dI/dx) of the fluorescence intensity (I) along the identified blood vessel structure (38) and the temporal gradient (dI/dt). An output frame (48) is displayed on a display (36) with time-varying marker data (52) overlaid on the identified blood vessels structure (38) and representative of the blood flow direction (42).

Abstract: The invention relates to an arm (1) adapted to be attached to a microscope (10), in particular a surgical microscope (10), wherein the arm (1) comprises at a distal end (21) a light beam deflection member (3) or a camera. An inventive microscope (10) comprises an arm (1).

Abstract: A signal to noise ratio adjustment circuit is configured to determine, whether a signal to noise ratio of a first image is below a first threshold and to determine, whether a variation of imaged content between the first image and a preceding second image of a video sequence is below a second threshold. The signal to noise ratio adjustment circuit is further configured to generate a third image having an increased signal to noise ratio as compared to the first image or the second image if the signal to noise ratio is below the first threshold and if the variation is below the second threshold.

Abstract: A surgical microscope, a method for observing an object in an observation area during surgery, and a retrofit-kit for a surgical microscope are provided. The surgical microscope includes at least one optical carrier for variably deflecting an observation axis of an optical observation assembly into an optical viewing axis directed towards the observation area. The optical carrier includes at least one optical beam deflector and is arranged between the optical observation assembly and the observation area. The optical carrier further includes a movable range-setting system for supporting the at least one optical beam deflector and for positioning the at least one optical beam deflector at a variable distance from the optical observation assembly.

Abstract: The invention relates to a medical inspection apparatus (1), such as a microscope or endoscope, and to a medical inspection method such as microscopy or endoscopy. Visible image data (11) representing a visible-light image (49) and fluorescence image data (12) representing a fluorescent-light image (51) and a pseudocolor (70, 71) are merged to give an improved visual rendition of an object (2) which comprises at least one fluorophore (6) to mark special features of the object (2). This is accomplished in that an image processing unit (18) of the microscope (1) or endoscope is configured to compute a color (ro, go, bo) of an output pixel (54) in the pseudocolor image (53) from at least one pseudocolor (rp, gp, bp), a color (ri, gi, bi) of a first input pixel (50) in the visible-light image (49) and an intensity (f) of a second input pixel (52) in the fluorescent-light image (51).

Abstract: The invention relates to a method for automatedly aligning a stand (12) for a microscope (14), wherein the stand (12) for the microscope (14) comprises controllable positioning means (16) for positioning the microscope (14) and controllable orienting means (18) for orienting the microscope (14). The method comprises defining a target point (24) to be observed by the microscope (14), wherein the target point (24) is located within a coordinate range accessible by the stand (12), stabilizing the microscope (14) at a user determined position in an automated manner by means of the controllable positioning means (16) of the stand, and adjusting an orientation of the microscope (14) at the user determined position to the target point (24) in an automated manner using the controllable orienting means (18) of the stand. The invention further relates to a stand, a microscope assembly (10), a control unit, a computer program and a computer-readable data storage.

Abstract: The present invention relates to a surgical microscope (1) with a field of view (9) and comprising an optical imaging system (3) which images an inspection area (11) which is at least partially located in the field of view (9), and to a method for a gesture control of a surgical microscope (1) having an optical imaging system (3). Surgical microscopes (1) of the art have the disadvantage that an adjustment of the microscope parameters, for instance the working distance, field of view (9) or illumination mode, requires the surgeon to put down his or her surgical tools, look up from the microscope's eyepiece (5) and perform the adjustment by operating the microscope handles. Also foot switches and mouth switches where proposed, whereas those are not intuitively operated, require training and are less accurate than hand control of the microscope handles. Thus, the surgeon may lose his or her focus, is confronted with inconveniences and delays and bears an increased risk of contamination.

Abstract: An image processing device (100) for a medical observation device (102), such as a microscope (104) or endoscope, is disclosed. The image processing device (100) comprises an image processor (106). The image processor (106) is configured to obtain a digital pseudocolor pattern (116), which has a pattern characteristic (118) and comprises a pseudocolor (120). The image processor (106) is further adapted to combine the digital pseudocolor pattern (116) with an input area (122) of retrieved digital input image (108, 110), thus forming a patterned region (124). Moreover, the image processor (106) is adapted to vary the pattern characteristic at a location (126) in the patterned region (124) depending on one of the intensity (I) and brightness (B) at a corresponding location (128) in the input area (122) of at least one of the digital input images (108, 110) and retrieved digital input image (108, 110); and to output at least one digital output image (130) comprising the patterned region (124).

Abstract: The invention relates to a method, in particular a fluorescence microscopy or endoscope imaging method for intensity normalization, a non-transient computer readable storage medium (101) and a controller (51) for an endoscope (3) or microscope device (5). In the prior art, common observation devices (1) as surgical microscopes, endoscopes (3) or microscopes (5) have the disadvantage that it is ambiguous whether a detected intensity (97) is due to fluorophore (29) concentration or due to optics setting parameters (73). The inventive method overcomes said disadvantages by automatically adjusting at least one exposure control parameter (83) if at least one optics setting parameter (73) is changed.

Abstract: An image-processing device (64) for a fluorescence observation device (1), such as a microscope or endoscope, emulates a first type (82) of fluorescence display device on a second type (63) of fluorescence display device (1). Proficient use of a fluorescence observation device (1) for surgery requires years of training and experience. As technology quickly advances, new types of fluorescence observation devices provide different and more information than older types of fluorescence observation devices, however adoption of newer types is slow because new training is needed. The present disclosure facilitates the switch from one type of fluorescence observation device to another by providing a type-emulation module (108), which allows the imaging result obtained from the first type of fluorescence observation device to be emulated on the second type. The type-emulation module (108) is applied to a digital fluorescence image (20) in which the fluorescence of a fluorescing fluorophore (8) is recorded.

Abstract: A method and system for computing an HDR image (38) from a digital color input image (4) of an object (30) containing a fluorescing fluorophore (22) acquires the input image using a color camera (2) having at least two different types (16, 17, 18) of color sensor (8), such as an R, G and B sensor. The input image may be recorded in a co-sensing wavelength band (64, 66, 68) wherein different spectral responsivities (58, 60, 62) of the different types of color sensor overlap. The input image comprises different digital monochrome input images (6), each recorded by a different type of color sensor. Light incident on the camera may be filtered using a band-pass filter (32) having a tunable pass band (34) which defines the co-sensing wavelength band and may be adjusted depending on spectral responsivities of the color sensors, the fluorophore, and characteristics of the monochrome input images.

Abstract: The invention relates to an apparatus (1) for tracking a movable target (3), in particular tissue (5), the apparatus (1) comprising at least one applicator (7) for marking the target (3) with at least one type of markers (11), and at least one tracking system (9) which is adapted for monitoring at least the at least one type of markers (11). In order to provide an apparatus and a method for tracking a movable target (3), in particular tissue (5) which improve the reliability of the target tracking and which reduce the risk of damaging a target, it is intended according to the invention that the at least one applicator (7) is adapted for generating a randomly distributed pattern (13) of markers (11) on the target (3).

Abstract: The invention relates to an optical filter (1) for transmitting light (13) of a pass wavelength (17), comprising at least two optical filter stages (3) arranged along a transmission direction (11), along which the light (13) of the pass wavelength (17) is transmitted through the optical filter (1), wherein each of the at least two optical filter stages (3) comprises at least one entrance polarizing element (5) and at least one constant retarding element (7). The invention further relates to a camera (53) for simultaneously capturing at least two images, wherein each image is limited to light (13) in a limited spectral band (44) and to a multi-spectral imaging system (87) and an illumination system (73) applying the inventive optical filter (1). Solutions of the art have low peak transmission values and may furthermore only provide monochrome images in real time.

Abstract: The invention relates to a catadioptric medical imaging system (1), in particular a surgical microscope (2). During surgery, it may be necessary to gain more information about a surgical cavity (6), in particular the type of tissue (29) at the inside walls (4) of the surgical cavity (6). To solve this problem, the catadioptric medical imaging system (1) according to the invention comprises a camera device (8) and a convex catoptric mirror (20) adapted to be inserted into the surgical cavity (6). The catoptric mirror (20) is mounted on an arm (22) and spaced apart from the camera device (8).

Abstract: A controller for a microscope is configured to receive image data representing a wound and to determine a line of sight to a bottom of the wound using the image data. The controller is further configured to output a control signal for the microscope, the control signal instructing the microscope to align its optical axis with the line of sight.

Abstract: The invention relates to a balancing device (14) for balancing a microscope (12) with respect to a rotation axis (1000), the balancing device (14) comprising a balancing weight (16) arranged around and assigned to the rotation axis (1000), such that the balancing weight (16) is rotatable around the rotation axis (1000), wherein a center of mass of the balancing weight (16) is arranged apart from the rotation axis (1000). The balancing device (14) further comprises a lever (18) for indicating a torque acting on the balancing device (14) and/or on the balancing weight (16), wherein the lever (18) is arranged around and assigned to the rotation axis (1000) to be rotatable around the rotation axis (1000), wherein the lever (18) extends within the balancing weight (16) and is movable by the torque within a predetermined range with respect to the balancing weight (16), and wherein an electrical potential of the lever (18) is set to a predetermined first potential value.

Abstract: The invention relates to an illumination system (10) for a fluorescence microscope (3) for observation of an object (17) containing at least one fluorophore (19), to a microscope (1) and to a microscope method for illumination of an object (17) comprising at least one fluorophore (19). Solutions of the art have the disadvantage that orientation within an object (17) is difficult and visibility of fluorescing regions of the object (17) is non satisfying.

Abstract: Medical observation apparatus (1) and method for observing an object or patient (67) in an operation area (21). Solutions of the art (3, 5) do not allow displaying further information, are expensive, bulky and non-intuitive.

Abstract: A beam splitter device (1) for a microscope (2), and for a microscope imaging method, supports at least two beamsplitting surfaces (4, 14). The two beamsplitting surfaces (4, 14) have different reflection-to-transmission ratios. The beam splitter device (1) has an optical path (3, 3a, 3b). A first one of the two beamsplitting surfaces (4, 14) is configured to be moved from a first operation position (15), in which the first beamsplitting surface (4) is located in the optical path, to a second operation position (16), in which a second (14) of the beamsplitting surfaces (4, 14) is located in the optical path. With this configuration, it is possible to change the available light in the branches (3a, 3b) of the optical path (3) after the beamsplitting surface (4, 14). This is useful if one of the branches (3a, 3b) is directed to an exit port (8) configured to receive a camera. By directing more light to the camera exit port (8), the image quality of the camera is improved.