Abstract: The present invention relates to an illumination filter system (2) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, such as a surgical microscope, in particular a surgical multispectral fluorescence microscope, comprising a first optical filter (35). The present invention also relates to an observation system (3) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, in particular a multispectral fluorescence microscope, comprising a beam splitter (21) adapted to split a light image (13) into a first light portion (16, 17) along a first light path (18) and a second light portion (20) along a second light path (19).

Abstract: The present invention relates to a coded zoom knob (3) for detecting the rotation of the zoom drive shaft (4) of a zoom system (10) of a microscope (1), comprising a stator (40) and a rotor (30) rotatable in relation to the stator (40), the rotor (30) being adapted to be mounted to the zoom drive shaft (4), and the stator (40) comprising a rotation sensor (43) for sensing a rotation of the rotor (30), and to a method of retrofitting a microscope with such a coded zoom knob (3).

Abstract: The invention relates to a method, an image processor (26) and a medical observation device (1), such as a microscope or endoscope, for observing an object (4) containing a bolus of at least one fluorophore (12). The object (4) is preferably live tissue comprising several types (16, 18, 20) of tissue. According to the method, a set (34) of component signals (36) is provided. Each component signal (36) represents a fluorescence intensity development of the fluorophore (12) over time in a different type of tissue. A time series (8) of input frames (10) is accessed, one input frame (10) after the other. The input frames (10) represent electronically coded still images of the object (4) at subsequent time. Each input frame (10) contains at least one observation area (22) comprising at least one pixel (23).

Abstract: The invention relates to a transmitted light illumination apparatus (2) for a microscope (1), said transmitted light illumination apparatus (2) comprising, a planar light source (20), a mirror (23) having a concave mirror surface (24) arranged in the direction of light emitted from the planar light source (20), and at least one diaphragm element (22) being at least partially opaque and being arranged between the planar light source (20) and the concave mirror surface (24) such that by moving the at least one diaphragm element (22) in at least one direction parallel to a plane defined by the planar light source (20), the planar light source (20) is at least partially covered by the at least one diaphragm element (22).

Abstract: A microscope (10) for obtaining a high dynamic range synthesized image (21) of an object (12) from a plurality of low dynamic range input images (19) comprises a controller (14), an incoherent light source (16) for illuminating the object (12) at different light intensity levels, and a recording device (18) for recording the plurality of low dynamic range input images (19), wherein each of the low dynamic range input images (19) is recorded at a different light intensity level. The controller (14) is configured to control the recording device (18) such that during recording of the series of the low dynamic range images the recording parameters for obtaining the plurality of low dynamic range input images (19) are kept constant.

Abstract: A microscope arrangement includes a plurality of microscopes, and a control device having a display screen and a data link. The display screen is configured to show microscopy data of the microscopes via the data link using display symbols, each display symbol representing microscopy data received by the control device from a different one of the microscopes. In at least one operational state of the control device, the display symbols are moveable on the display screen to correspond to an arrangement of the microscopes.

Abstract: An illumination and observation system (1) for an ophthalmic surgical microscope (2) has first, second, third and fourth observation pupils (4, 5, 8, 9) for two observers, a coaxial illumination (6, 10, 11) in the first, third and fourth observation pupils to generate a red reflex (13) therein, and a main illumination (7) in the second observation pupil. For widely illuminating the surroundings, the main illumination has a larger illumination field than the coaxial illumination in any of the first, third and fourth observation pupils. For superior observation quality and a visible and homogenous red reflex in the second observation pupil, the main illumination overlaps at least 50% with the second observation pupil. The main illumination may be aligned within ±5° to an optical axis (12) of the second observation pupil and to overlap the coaxial illumination at least 50% with the first, third and fourth observation pupils.

Abstract: An illumination and observation system (1), in particular for an ophthalmic microscope, comprises a first observation pupil (4) and a second observation pupil (5) for the eyes of an observer such as an assistant. Further, the system comprises a coaxial illumination (6) in the first observation pupil (4) and a main illumination (7), the coaxial illumination (6) being adapted to generate a red reflex (13) in the observed eye in operation and the main illumination having a larger field of illumination than the coaxial illumination (6, 10, 11). To facilitate usage of the system (1) and/or the microscope (2) and to create a superior stereoscopic view using the red reflex (13), a control subsystem (21, 27) is provided which is adapted to automatically adjust an intensity of the main illumination (7) depending on a change in an intensity of the coaxial illumination (6).

Abstract: A microscope arrangement includes a plurality of microscopes arranged in a geometric pattern. A control device has a display screen and a data link. The data link connects the microscopes to the control device and is configured to transfer microscopy data at least from the microscopes to the control device. The display screen comprises display symbols. Each display symbol represents microscopy data received by the control device from a different one of the microscopes. The display symbols are, in at least one operational state of the control device, arranged moveable on the display screen and are adapted to be moved into the geometric pattern.

Abstract: A microscope (10) for generating a combined image (34; 54; 64) from multiple individual images (28a to 28d; 52a to 52d; 62a to 62d) of an object (30; 50; 60) encompasses at least one illumination device (22) for illuminating the object (30; 50; 60) from at least two different illumination directions (24a, 24b); an image acquisition unit (26) for acquiring multiple individual images (28a to 28d; 52a to 52d; 62a to 62d) of the object (30; 50; 60) illuminated from the at least two different illumination directions (24a, 24b); and an image combination unit (32) for combining the individual images (28a to 28d; 52a to 52d; 62a to 62d) in order to obtain the combined image (34; 54; 64).

Abstract: The invention relates to an illumination unit that encompasses two light sources arranged one behind another in a channel . A cooling unit is provided respectively at the two ends of the channel. The invention further relates to an energy supply unit for supplying the illumination unit with electrical energy. The energy supply unit encompasses two energy sources arranged in a channel. Respective cooling units are arranged at the two ends of the channel.

Abstract: The present invention provides a pivotable optical assembly for a surgical microscope, specifically a zero-degree assistant's device, the assembly comprising: a microscope body interface for mounting the assembly on a microscope body; an assistant's module including an interface for an assistant's tube, the assistant's module being pivotable about a pivot axis relative to the microscope body; and a retaining system that blocks pivoting the assistant's module about the pivot axis. The retaining system comprises: a retaining element being moveable from a locking position into a release position, a biasing member forcing the retaining element into the locking position, and a hand-operable control element acting on the retaining element for moving it from the locking position into the release position, as well as a pivotable optical assembly comprising said retaining system according to the invention, whose retaining element, in its blocking position, blocks pivoting the assistant's module about the pivot axis.

Abstract: The invention relates to an iris device (1) for optical imaging systems (71), comprising an aperture arrangement (5) and to a medical imaging system (72) comprising a sensor (15), in particular a camera (15a). Conventional iris devices (1) known from the art unavoidably suffer a necessary trade-off between the depth of field and the amount of light transmitted through the optical system (71), i.e. in particular the amount of light incident on the sensor (15). This disadvantage results from the fact that iris devices (Wo one) of the art transmit or reject light in the same way for all wavelengths (43), i.e. show a spectrally flat transmission property.

Abstract: The invention relates to an illumination filter (36, 44) for an illumination filter system (2) for medical imaging, in particular multispectral fluorescence imaging, as performed e.g. in a microscope (1) or endoscope, in particular a multispectral fluorescence microscope. The present invention provides an illumination filter for medical imaging, in particular a multispectral fluorescence imaging, that is capable of capturing simultaneously more than one fluorescence signal, and allow a homogeneous illumination for obtaining different images from the object illuminated by comprising a spatial filter pattern (43) masking a defined filtering fraction of a first illumination path (47) on the filter and masking a defined filtering fraction of a second illumination path (48, 49, 50) on the filter, wherein the filtering fraction of the first and the second illumination paths (47, 48, 49, 50) are different.

Abstract: The invention relates to a microscope (10) having a movable stage (18) and an adjusting unit (24) for moving the stage (18). The adjusting unit (24) comprises a drive shaft (38) by the rotation of which the distance between the stage (18) and a base (22) of the microscope (10) is adjustable. Further, the microscope (10) has a manually operable operating unit (26) with a first output shaft (46) as well as an electric drive unit (28) for the motorized movement of the stage (18) with a second output shaft (52). In a manual operating mode, the drive shaft (38) is coupled to the first output shaft (46) via a first coupling unit (54), and in a motorized operating mode the drive shaft (38) is coupled to the second output shaft (52) via a second coupling unit (56).

Abstract: The invention relates to a method of displaying a system state of an automatic treatment device, a corresponding display system which is configured for carrying out the method, and a treatment device equipped with the display system. At least one system parameter (121, 122, 123) is determined, the at least one determined (120) system parameter (121, 122, 123) is evaluated on the basis of evaluation criteria, the system state is evaluated on the basis of the at least one evaluated (130) system parameter (121, 122, 123), and the evaluated (140) system state is displayed by a traffic light function (175).

Abstract: A device (20) for processing tissue samples has a processing room (22) for introducing and processing the tissue samples (20). A chamber (34) communicates with the processing room (22). At least one filling level sensor (28, 30, 32) detects a measurement value which is representative of a filling level of a liquid in the chamber (34). A calculating unit determines a filling level of the liquid in the processing room (22) depending on the filling level of the liquid in the chamber (34).

Abstract: A method and an apparatus are described for infiltrating tissue samples with carrier material, preferably paraffin. A supply of carrier material is kept ready for use in a supply station. From there, the carrier material can be delivered into at least a first and a second container. In these first and second containers carrier materials of differing degrees of purity are kept ready for use, respectively, for performing various infiltration steps on tissue samples. By means of the described method and apparatus the tissue processor can be operated with as little interruptions as possible and an ease in operation is achieved.

Abstract: The invention relates to a method of displaying a system state of an automatic treatment device, a corresponding display system which is configured for carrying out the method, and a treatment device equipped with the display system. At least one system parameter (121, 122, 123) is determined, the at least one determined (120) system parameter (121, 122, 123) is evaluated on the basis of evaluation criteria, the system state is evaluated on the basis of the at least one evaluated (130) system parameter (121, 122, 123), and the evaluated (140) system state is displayed by a traffic light function (175).

Abstract: A stand for a surgical microscope is suggested that is provided with vertical and horizontal supports; articulation units; and a displacement unit that is attached to one of the articulation units. At least one pivot support is provided and encompassed by the displacement unit. A displacer is provided at the pivot support. The pivot support has a pivotable parallelogram support that is provided with a spring or a gas damper as energy storing device that interconnects and supports movement of the movable parts in the interior of the parallelogram support assisting with a stored force in a displacement movement. A holding arm is attached to the pivotable parallelogram support and simultaneously serves for displacing the optics carrier in the X direction.