Patents Assigned to LIFE SCIENCES, LLC
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Publication number: 20200323701Abstract: Various examples of a wearable sensor enclosure are described. In an example, a wearable sensor enclosure is generally oval-shaped with rigid interior that protects one or more sensors or other electronic devices. The enclosure includes a proximal component and a distal component. The proximal component of the enclosure optionally includes one or more openings for light to pass through for detection by sensing electronic devices. The distal component includes a protrusion positioned in an interior of the distal component and a lip positioned in along the perimeter of the distal component such that the lip surrounds the protrusion.Type: ApplicationFiled: April 12, 2019Publication date: October 15, 2020Applicant: Verily Life Sciences LLCInventors: Michael Jastrzebski, Kristin Size, David He, Harry Xiao, Linden Evans
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Patent number: 10798924Abstract: An emergence apparatus may include a container, a sensor, and a shutter. The sensor may be positioned proximate to an opening in the container to detect an adult insect entering or exiting the container. The sensor may also determine a sex of the adult insect. The shutter may also be positioned proximate to the opening to the container and may include an open position and a closed position to control access to the container in response to determining the sex of the adult insect or in response to determining a total number of adult insects of a particular sex within the container.Type: GrantFiled: April 29, 2019Date of Patent: October 13, 2020Assignee: VERILY LIFE SCIENCES LLCInventors: Peter Massaro, Robert Sobecki, Tiantian Zha, Brian Wasson
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Patent number: 10804598Abstract: One example device having a variable impedance matching network includes a flexible substrate configured to flex in at least an X dimension and a Y dimension, wherein the X and Y dimensions are orthogonal and coplanar with a surface of the flexible substrate; an antenna formed on the flexible substrate, the antenna deformable in at least one of the X or Y dimensions, wherein an inductance (“LA”) of the antenna varies based on a flexing of the flexible substrate in the at least one of the X or Y dimensions, an impedance matching network formed on the flexible substrate and coupled to the antenna, the impedance matching network deformable in the at least one of the X or Y dimensions, and wherein a capacitance (“CM”) or inductance (“LM”) of the impedance matching network is configured to vary (i) based on the flexing of the flexible substrate in the at least one of the X or Y dimensions and a separation between two portions of the impedance matching network, and (ii) in proportion to the varying of LA to maintaiType: GrantFiled: December 19, 2018Date of Patent: October 13, 2020Assignee: Verily Life Sciences LLCInventors: Peng Cong, You Zou
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Patent number: 10791976Abstract: A system for needle-free drawing of blood is disclosed. A hand-portable device can include an evacuated negative-pressure barrel with a membrane sealing an aperture at a distal end, and a housing affixed to a proximal end. An accelerator barrel can be positioned within the negative-pressure barrel and fixed to the housing, with an open proximal end in a chamber in the housing, and an open distal end aligned with the aperture. The chamber can be filled with pressurized gas, and a trigger valve can hydrostatically separate the chamber from the open proximal end of the accelerator barrel. A micro-particle positioned within the accelerator barrel can be accelerated to high speed by an abrupt surge of gas by releasing the trigger valve. The micro-particle can attain enough momentum to pierce the aperture membrane and penetrate adjacent dermal tissue. A resulting micro-emergence of blood can be drawn into the negative pressure barrel.Type: GrantFiled: July 13, 2017Date of Patent: October 6, 2020Assignee: Verily Life Sciences LLCInventors: Eric Peeters, Peter Howard Smith
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Publication number: 20200305406Abstract: An insect trapping system includes an enclosed container having an entrance hole formed in a vertical wall and an acoustic lure device located within the container. The enclosed container may be formed from a transparent material. The system may also include a support stand, formed from a dark-colored material, and used to support the container.Type: ApplicationFiled: January 24, 2020Publication date: October 1, 2020Applicant: Verily Life Sciences LLCInventors: Scott Ritchie, Kyran M. Staunton, Wei Xiang, Yu Han, Nigel Snoad, Jianyi Liu, Jacob Crawford, Mark Desnoyer
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Publication number: 20200311929Abstract: In one embodiment, a system for biomedical object segmentation includes one or more processors; one or more memory modules communicatively coupled to the one or more processors, and machine readable instructions stored on the one or more memory modules. The machine readable instructions cause the system to perform the following when executed by the one or more processors: receive image data of one or more biological constructs; analyze the image data to generate processed image data via a data analytics module to recognize biomedical objects; and automatically annotate the processed image data to indicate a location of one or more biological objects within the one or more biological constructs.Type: ApplicationFiled: March 27, 2020Publication date: October 1, 2020Applicant: Advanced Solutions Life Sciences, LLCInventors: Jeremy Johnson, Robert Eli, Alexander Charles Schultz, Jay Hoying
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Publication number: 20200307101Abstract: According to one or more embodiments, a system for detecting defects in a printed construct includes one or more processors, one or more image sensors, and one or more memory modules. The one or more image sensors are communicatively coupled to the one or more processors. Machine readable instructions are stored on the one or more memory modules that, when executed by the one or more processors, cause the system to collect image data of a three-dimensional printed construct from the one or more image sensors, and detect one or more defects within the image data of the three-dimensional printed construct.Type: ApplicationFiled: March 26, 2020Publication date: October 1, 2020Applicant: Advanced Solutions Life Sciences, LLCInventors: Alex Schultz, Jeremy Johnson, Robert Eli
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Patent number: 10786164Abstract: Systems and methods are provided for determining the frequency of a cardiovascular pulse based on a first physiological signal that is continuously available and a second physiological signal that is less available and that is more accurate or otherwise improved relative to the first signal with respect to pulse rate estimation. When the second signal is available it controls the determination of the pulse rate. When the second signal is unavailable, the first signal is used to determine the pulse rate. This can include using the first signal to estimate the pulse rate until the second signal is available, at which point the pulse rate is estimated based on the second physiological signal. Alternatively, the first signal could be used to determine a number of candidate pulse rates, and the second signal could be used to select a pulse rate from the set of candidate pulse rates.Type: GrantFiled: November 8, 2016Date of Patent: September 29, 2020Assignee: Verily Life Sciences LLCInventors: Mark Murphy, Russell Norman Mirov, Christopher Towles Lengerich
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Publication number: 20200302600Abstract: One example method for identifying useful segments in surgical videos includes accessing a video of a surgical procedure and user activities of a plurality of users who have watched the video of the surgical procedure. The user activities include operations performed during playback of the video. The method further includes dividing the video into multiple segments and determining a popularity score for each of the multiple segments based on the operations. Useful segments are identified from the segments based on the popularity scores. The method further includes generating metadata for the video of the surgical procedure to include an indication of the identified useful segments and associating the metadata with the video of the surgical procedure.Type: ApplicationFiled: March 3, 2020Publication date: September 24, 2020Applicant: Verily Life Sciences LLCInventors: Joëlle Barral, Martin Habbecke, Lin Yang, Xing Jin
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Publication number: 20200299246Abstract: Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g., protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g., a cancer or a metabolic disease.Type: ApplicationFiled: June 4, 2020Publication date: September 24, 2020Applicants: Calico Life Sciences LLC, AbbVie Inc.Inventors: Geoff T. Halvorsen, Jennifer M. Frost, Philip R. Kym
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Publication number: 20200298264Abstract: Systems and methods for determining the identity of a liquid within a liquid dispenser are provided. A device includes a holder having an opening that is configured to retain the liquid dispenser. A surface of the liquid dispenser is configured to affix a label identifying a liquid within the liquid dispenser. A plurality of lenses are mounted on the holder. Each lens has a respective field of view that includes a respective portion of the surface of the liquid dispenser. In addition, the device includes a plurality of fiber bundles. Each fiber bundle includes an input that is configured to receive a respective signal from a respective one of the plurality of lenses. Further, the device includes an imaging sensor that is configured to receive the respective signals from the plurality of fiber bundles and to form a plurality of images of the surface of the liquid dispenser.Type: ApplicationFiled: March 16, 2020Publication date: September 24, 2020Applicant: Verily Life Sciences LLCInventors: Supriyo Sinha, Michael Allen, Todd Whitehurst, Dimitri Azar
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Publication number: 20200296920Abstract: An insect storage and release device includes suitably rigid container that may be used to store and transport insects. The insect storage and release device may hold compressed insects or non-compressed insects. The insect storage and release device includes a removable enclosure and a reticulated foam for adding compliance during packing of the insects.Type: ApplicationFiled: March 16, 2020Publication date: September 24, 2020Applicant: Verily Life Sciences LLCInventors: Charles Behling, Brian Wasson
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Patent number: 10785562Abstract: Introduced here are recording devices optimized for recording speech between multiple parties (e.g., a speaker and a counterparty, or a first speaker and a second speaker). These recording devices can facilitate the discovery of personalized characteristics of an interaction by detecting location. For example, these recording devices can discover the intent behind certain terms and phrases in the context of a conversation. A recording device can include a communication module configured to stream recorded media content to another electronic device, as well as a marker identification module configured to identify nearby beacons. For example, a recording device may include a Bluetooth® Low Energy chipset configured to identify nearby Bluetooth® beacons and a Wi-Fi® chipset configured to stream recorded media content to another electronic device.Type: GrantFiled: November 29, 2018Date of Patent: September 22, 2020Assignee: Verily Life Sciences LLCInventor: David Emmanuel Weekly
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Patent number: 10779521Abstract: Embodiments of the present disclosure can provide an automated mass rearing system for insect larvae. The automated mass rearing system can facilitate hatching, feeding, monitoring the growth and emergence of insect larvae and pupae. In some embodiments, the automated mass rearing system can include a production unit, a transportation unit, a storage unit, a dispensing unit, and a monitoring unit. In some embodiments, this automated mass rearing system can facilitate mass mosquito growth from egg hatching all the way through to full adults or certain stages in between such as the larvae rearing process (i.e., from larvae to pupae) with little or no human intervention. By automating the rearing and transportation of insect eggs, larvae, and pupae, deaths or developmental issues can be minimized. Various techniques and apparatuses are used in this automation that causes minimal disturbance to the insects during development, and thereby maximizing survival rate and fitness of the insects.Type: GrantFiled: September 27, 2017Date of Patent: September 22, 2020Assignee: Verily Life Sciences LLCInventors: Peter Massaro, Robert Sobecki, Charles Behling, Victor Criswell, Tiantian Zha, Roman Devengenzo
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Patent number: 10773075Abstract: An electrode cuff for placement around a peripheral nerve can include one or more protrusions extending from a tissue-contacting surface of the electrode cuff. A protrusion can include one or more electrodes and can have a blunt distal end. The protrusion(s) can be driven into the nerve using a driving tool designed to apply mechanical oscillations and/or swift mechanical force to the electrode cuff. The mechanical oscillations and/or swift mechanical force can insert the blunt distal ends of the protrusions into the nerve without damaging fascicles within the nerve. During implantation, a sensor associated with the driving tool and/or the electrode cuff can provide dynamic feedback to a controller for controlling the driving tool. The sensor may detect pressure, temperature, acoustic activity, and/or electrical activity to indicate when the protrusions have pierced the epineurium, allowing the controller to cease the driving tool and thus avoid damage to the fascicles.Type: GrantFiled: March 20, 2018Date of Patent: September 15, 2020Assignee: VERILY LIFE SCIENCES LLCInventors: Brian Pepin, Peng Cong, Kedar Shah, Shivkumar Sabesan
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Patent number: 10776667Abstract: Embodiments may include a method to estimate motion data based on test image data sets. The method may include receiving a training data set comprising a plurality of training data elements. Each element may include an image data set and a motion data set. The method may include training a machine learning model using the training data set, resulting in identifying one or more parameters of a function in the machine learning model based on correspondences between the image data sets and the motion data sets. The method may further include receiving a test image data set. The test image data set may include intensities of pixels in a deep-tissue image. The method may include using the trained machine learning model and the test image data set to generate output data for the test image data set. The output data may characterize motion represented in the test image data set.Type: GrantFiled: August 13, 2018Date of Patent: September 15, 2020Assignee: VERILY LIFE SCIENCES LLCInventors: Eden Rephaeli, Daniele Piponi, Chinmay Belthangady, Seung Ah Lee
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Patent number: 10774377Abstract: This disclosure generally relates to improved methods, compositions, and systems for detecting, quantifying, and characterizing genomic sequences from heterogeneous genomic samples. The disclosed methods include providing a unique molecular identifier to the initial target sequences prior to amplification and addition of indexing barcodes. The methods, compositions, and systems can be employed to accurately detect and quantify operational taxonomic units from heterogeneous samples and further to detect sequencing errors, e.g., chimeric sequences, which may occur during the development and sequencing of the library.Type: GrantFiled: October 5, 2017Date of Patent: September 15, 2020Assignee: VERILY LIFE SCIENCES LLCInventors: Vanessa Ridaura, Jerrod George Schwartz
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Patent number: 10772309Abstract: A sieving apparatus for separating insect pupa is described. In an example, the sieving apparatus includes a sieving device attached to an actuation system. The sieving device includes a set of openings sized to correspond to a cross-sectional cephalothorax width of a representative pupa of a population of insect pupae to be separated. The actuation system is configured to move the sieving device in a manner that causes smaller insect pupae to pass through the set of openings. Larger insect pupae remain within the sieving device. Such movement can include moving the sieving device with respect to a liquid held in a basin of the sieving apparatus.Type: GrantFiled: October 8, 2018Date of Patent: September 15, 2020Assignee: Verily Life Sciences LLCInventors: Robert Sobecki, Charles Behling
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Publication number: 20200282393Abstract: Modular pump assemblies according to the present disclosure include a plurality of mounting frames configured to be stackable with one another in a modular configuration, and an array of pumps mounted to each of the plurality mounting frames, the array of pumps comprising an array of inlet pumps configured to be fluidically coupled a plurality of fluid inlet paths of a well-plate manifold or an array of fluid outlet pumps configured to be fluidically coupled to a plurality of fluid outlet paths of the well-plate manifold, or any combination thereof.Type: ApplicationFiled: March 6, 2020Publication date: September 10, 2020Applicant: Advanced Solutions Life Sciences, LLCInventor: Scott Douglas Cambron
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Publication number: 20200281467Abstract: One example system includes a biosensor applicator having a housing defining a cavity configured to receive and physically couple to a biosensor device, and to apply the biosensor device to a wearer; an applicator coil antenna oriented around a first axis; and a biosensor device including a biosensor coil antenna; a first wireless transceiver electrically coupled to the biosensor coil antenna; a Bluetooth antenna; and a second wireless transceiver coupled to the Bluetooth antenna; wherein the biosensor device is physically coupled to the biosensor applicator and positioned at least partially within the cavity; and wherein the applicator coil antenna is configured to wirelessly receive electromagnetic (“EM”) energy from a remote coil antenna and wirelessly provide at least a first portion of the received EM energy to the biosensor coil antenna.Type: ApplicationFiled: April 8, 2020Publication date: September 10, 2020Applicant: Verily Life Sciences LLCInventors: William Biederman, Anil Kumar Ram Rakhyani, Louis Jung, Stephen O'Driscoll