Abstract: A handheld tool includes a handle for holding by a user, an attachment arm extending from the handle that is configured to connect to a user-assistive device, a first inertial measurement unit (“IMU”) mounted to the attachment arm to acquire measurements of one or more of a motion or an orientation of the user-assistive device and to generate feedback data indicative of the measurements, an actuator assembly coupled to manipulate the user-assistive device via the attachment arm in at least two orthogonal dimensions, and a motion control system coupled to receive the feedback data from the first IMU and coupled to provide commands to the actuator assembly to provide auto-leveling of the user-assistive device to a frame of reference while the user manipulates the handheld tool.

Abstract: A storage assembly for storing a plurality of specimens includes a frame, a plurality of modular storage units for perfusion and/or incubation of one or more specimens removably coupled to the frame, a sample transfer apparatus configured to retrieve a specimen holder from a chosen modular storage unit of the plurality of modular storage units, and a control unit communicatively coupled to the sample transfer apparatus. The control unit is configured to cause the sample transfer apparatus to retrieve a specimen from a modular storage unit of the plurality of modular storage units and deliver the specimen to a delivery position.

Abstract: Systems and methods for triggering a drug injection device are disclosed. One disclosed system for injecting a substance into a patient includes: a chamber comprising a propellant; a light source mechanically coupled to the chamber, wherein energy from the light source ignites the propellant; and a power source electrically coupled to the light source via a control circuit, wherein the control circuit applies power to activate the light source.

Abstract: Systems are provided for detecting the flow of blood or other fluids in biological tissue by illuminating the biological tissue with a coherent light source and detecting time-varying patterns of constructive and destructive interference in light received from portions of the biological tissue by an imager. The movement of blood cells and other light-scattering elements in the biological tissue causes transient, short-duration changes in light emitted from portions of the biological tissue proximate to the moving blood cells or other scatterers. High-frequency sampling or other high-bandwidth processing of light intensities detected by an imager could be used to determine the flow of blood or other fluids at a plurality of points in the biological tissue, to detect and/or localize a tumor in the biological tissue, to determine the location, pattern, width, or other properties of vasculature in the biological tissue, or to provide information for some other application(s).

Abstract: This disclosure provides a method for adjusting the maturation state of mammalian sperm for use in assisted reproductive technologies (ART). A mammalian ejaculate is provided and incubated under controlled conditions. Aliquots of the ejaculate are assayed during incubation period at intervals to determine maturation state and changes in the maturation state by observing the percent positive cells in the aliquot. The assays are repeated with successive aliquots at intervals during incubation to observe real time changes in the maturation state. The ejaculate remaining is processed for the desired ART after the percentage of positive cells in the latest aliquot being assayed begins to decline.

Abstract: In one aspect, the present invention is directed to a method for preventing or treating necrotic enteritis by administering a hyperimmunized egg product obtained from an egg-producing animal to an avian. The hyperimmunized egg product may contain an antibody specific to an antigen selected from the group consisting of Clostridium perfringens ?-toxin, Clostridium perfringens elongation factor Tu (EF-Tu), Clostridium perfringens necrotic enteritis B-like (NetB) toxin, Clostridium perfringens Pyruvate: Ferredoxin oxidoreductase (PFO), and Eimeria tenella elongation factor 1-alpha.

Abstract: Introduced here are techniques for developing personalized retroactive insights into how contextual factors can affect glycemic responses. The personalized retroactive insights can be made available to the corresponding individual so that they can examine the impact certain contextual events have had on blood glucose level. A contextual event represents an activity or a circumstance that is related to glycemic response. Rather than state the absolute amount of certain molecules (e.g., carbohydrates, protein, or fat) in a foodstuff, an insight detection platform can instead interpret disparate data types to discover the effect certain contextual events have on blood glucose level.

Abstract: Provided herein are encapsulated liposomes comprising a lipid bilayer, a first polyethylene glycol (PEG) corona, a targeting molecule and a second PEG corona. The second, encapsulating PEG corona can be reversibly linked to the first PEG corona. Also provided are pharmaceutical compositions comprising the encapsulated liposomes and methods of treating a subject with a disease characterized by production of reactive oxygen species (ROS) with the compositions. Also provided are methods of making the encapsulated liposomes disclosed herein.

Abstract: Various apparatuses and methods for tracking the administration of medication by medication injection devices are provided. A plunger head for a medication injection device may include a first component that houses electronic components and a second component that couples to the first component to form the plunger head. When the plunger head is installed within a barrel of the medication injection device the second component may separate the first component from medication contained within the barrel.

Abstract: The present disclosure relates to systems and methods for activating a circuit of an implant device. Consistent with one implementation, an implant device is provided with a sensor including a working electrode (WE) and a counter electrode (CE). The sensor may be configured to generate a first current at the CE when the implant device is implanted in a body of a subject. A sensing circuit may also be provided that is electrically coupled to the WE of the sensor. The sensing circuit may be activated based on the first current and utilize the sensor to measure one or more parameters of an individual or other subject.

Abstract: An example system includes a flexible substrate configured to be mounted to a skin surface. The system includes a sensor probe that has a first end attached to the flexible substrate and a second end configured to extend beneath the skin surface to contact interstitial fluid. A sensor is configured to measure a physiological property and is disposed at the second end of the sensor probe. A transmitter is attached to the flexible substrate and is configured to provide information related to sensor measurements to a controller. The controller is configured to a drug delivery rate based on the information.

Abstract: In one aspect of the present disclosure, a method is disclosed. The method involves: a reader detecting an eye-mountable device within a wireless communication range of the reader, wherein the eye-mountable device includes a transparent material having a concave mounting surface configured to be removably mounted on a corneal surface; wirelessly retrieving from the detected eye-mountable device a first set of data; using the retrieved first set of data to determine that a condition has been satisfied; and responsive to using the retrieved first set of data to determine that the condition has been satisfied, retrieving from the detected eye-mountable device a second set of data.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for conducting user studies. One of the methods includes receiving a user study session request from a sponsor, wherein the user study session request identifies a product and one or more criteria. Session volunteer data identifying one or more available session volunteers having access to the product and one or more attributes is received. A session volunteer that satisfies the user study session request is determined, including matching the one or more attributes of the session volunteer to the one or more criteria of the session request. A session between the sponsor and the session volunteer is initiated.

Abstract: The disclosure describes an electrowetting contact lens comprising including an electrowetting cell. The cell includes first and second optical windows that form a sealed enclosure. A first electrode is formed on the first optical window, and a second electrode is formed on the second optical window. The first and second electrodes include an electrically conductive layer, and the first electrode includes at least one dielectric layer sandwiched between the relevant optical window and the at least one dielectric layer. Oil and saline layers are positioned in the sealed enclosure so that the oil is in contact with one electrode and the saline is in contact with the other electrode. A protective coating encloses the electrowetting cell, and a contact lens material encloses the sealing material. Other embodiments are disclosed and claimed.

Abstract: One method for fleet management of robotic surgical systems includes receiving, by a management server from a robotic surgery system, a provisioning request; in response to receiving the provisioning request: generating an encryption key pair for the robotic surgery system, the encryption key pair comprising a private key and a public key, communicating the private key to the robotic surgery system, and communicating a set of secure certificates to the robotic surgery system, at least one of the secure certificates enabling secure communications between the robotic surgery system and the management server; receiving from the robotic surgery system, and using the at least one secure certificate enabling secure communications, a message indicating one or more software packages, each software package indicating a version of an installed software package on the robotic surgery system; communicating one or more software updates to the robotic surgery system based on the message; and registering, at the management

Abstract: One example method for robotic surgery using multi-user authentication without credentials includes receiving, by a robotic surgical device, a case code associated with a medical procedure; validating the case code; determining one or more users associated with the case code; and providing access to the one or more users to the robotic surgical device to enable a robotic surgical procedure.

Abstract: Methods and devices are provided for optically interrogating subsurface tissues of a body. Optical interrogation includes illumination of a target tissue through an external body surface and detection of light emitted in response to the illumination. Parameters of such optical interrogation are controlled according to operational modes that are selected to maximize detector sensitivity to a target property of the target subsurface tissues. Operational modes are selected based on detected properties of the target tissue and of intervening tissues (e.g., thickness of intervening tissues between the target tissue and an external body surface) between the target tissue and an interrogating optical device. Operational modes can be determined based on simulated optical interrogation of subsurface tissue across a range of optical detector configurations and tissue conditions. Operational modes can include calibration curves specifying optical interrogation parameters based on intervening tissue properties.

Abstract: A bone implant includes a rod having an aperture extending entirely through the rod. The aperture is to receive a fastener to couple the rod to a bone of a patient. The bone implant also includes a light source disposed on the rod. The light source is to emit light onto a portion of the bone adjacent the rod to at least one of stimulate bone growth or reduce bone loss.

Abstract: A sieving method for separating insect pupae is described. The method may include causing an actuation system of a sieving apparatus to cycle between a first elevation and a second elevation to cyclically submerge a sieve surface of a sieving device in a liquid held within a basin so as to separate a population of insect pupae present in the sieving device with respect to size. The method may also include causing actuation of one or more valves to drain the liquid from the basin in order to retrieve a first part of the population of insect pupae. Corresponding computer-readable devices and systems that perform the sieving method are also described.

Abstract: The technology described herein is directed to a health-monitoring service that facilitates contextual grouping of sensor channels for healthcare monitoring. In some implementations, clustering algorithms and predictive models can be used to dynamically select the sensor channels associated with a mobile communication device that are monitored. In this manner, only those sensor channels that provide meaningful signals are monitored.