Patents Assigned to LifeCell Corporation
  • Electroporation of tissue products
    Patent number: 9919066
    Abstract: The present disclosure provides methods for reducing bioburden on a tissue product, as well as the tissue products produced according to the disclosed methods. In particular, the disclosure relates to methods of electroporating tissue in the presence of one or more bactericides in order to reduce bioburden. The methods allow for reduced exposure to electrical energy and/or bactericide while reducing bioburden.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: March 20, 2018
    Assignee: LifeCell Corporation
    Inventors: Gary Monteiro, Martin J. Byrne, Rick T. Owens
  • Flowable tissue products
    Patent number: 9913705
    Abstract: The present disclosure provides tissue fillers. The tissue fillers can include a plurality of tissue particles formed from acellular tissue matrix fragments. The tissue fillers can be used to fill tissue sites, such as voids formed after tissue resection.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: March 13, 2018
    Assignee: LifeCell Corporation
    Inventors: Mark Hayzlett, Ivis Munoz, Nimesh Kabaria, Joshua Czeczuga
  • FLOWABLE TISSUE MATRICES
    Publication number: 20170348353
    Abstract: Disclosed herein are flowable tissue matrix compositions comprising small pieces of partially or completely decellularized tissue suspended in a gelatinized tissue or gelatin gel comprising partially or completely decellularized tissue or synthetic gelatin. The flowable tissue matrix compositions can contain factors that promote or enhance native cell migration, proliferation, and/or revascularization after implantation into a subject. Also disclosed are methods of making and using the flowable tissue matrix compositions. The compositions can be implanted into a tissue in need of repair, regeneration, healing, treatment, and/or alteration, and can promote or enhance native cell migration, proliferation, and/or revascularization.
    Type: Application
    Filed: August 23, 2017
    Publication date: December 7, 2017
    Applicant: LifeCell Corporation
    Inventor: Wenquan Sun
  • Flowable tissue matrices
    Patent number: 9782436
    Abstract: Disclosed herein are flowable tissue matrix compositions comprising small pieces of partially or completely decellularized tissue suspended in a gelatinized tissue or gelatin gel comprising partially or completely decellularized tissue or synthetic gelatin. The flowable tissue matrix compositions can contain factors that promote or enhance native cell migration, proliferation, and/or revascularization after implantation into a subject. Also disclosed are methods of making and using the flowable tissue matrix compositions. The compositions can be implanted into a tissue in need of repair, regeneration, healing, treatment, and/or alteration, and can promote or enhance native cell migration, proliferation, and/or revascularization.
    Type: Grant
    Filed: April 23, 2013
    Date of Patent: October 10, 2017
    Assignee: LifeCell Corporation
    Inventor: Wenquan Sun
  • BIOLOGIC BREAST IMPLANT
    Publication number: 20170224869
    Abstract: The present disclosure provides tissue products produced from adipose tissues, as well as methods for producing such tissue products. The tissue products can include acellular tissue matrices produced in multiple layers for treatment of a breast.
    Type: Application
    Filed: January 26, 2017
    Publication date: August 10, 2017
    Applicant: LifeCell Corporation
    Inventors: Mrinal Shah, Yi Chen, Sangwook Park, Israel Jessop
  • Dry Platelet Composition
    Publication number: 20170136064
    Abstract: The invention features a dry platelet composition and methods of making and using the freeze-dried platelet composition.
    Type: Application
    Filed: December 1, 2016
    Publication date: May 18, 2017
    Applicant: LifeCell Corporation
    Inventors: Christopher T. Wagner, Jerome Connor, John R. Harper
  • Systems and methods for sterilization of bone or bone components
    Patent number: 9649408
    Abstract: Systems for sterilization of demineralized bone matrices are provided.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: May 16, 2017
    Assignee: LifeCell Corporation
    Inventors: Qiu Qing-Qing, Jerome Connor
  • Method for shaping tissue matrices
    Patent number: 9636435
    Abstract: Methods for shaping tissue matrices are provided. The methods can be used to produce shaped tissue products that retain desired biologic properties without using chemical crosslinking agents.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: May 2, 2017
    Assignee: LifeCell Corporation
    Inventors: Wendell Sun, Gary Monteiro
  • METHOD FOR SHAPING TISSUE MATRICES
    Publication number: 20170100509
    Abstract: Methods for shaping tissue matrices are provided. The methods can be used to produce shaped tissue products that retain desired biologic properties without using chemical crosslinking agents.
    Type: Application
    Filed: December 14, 2016
    Publication date: April 13, 2017
    Applicant: LifeCell Corporation
    Inventors: Wendell Sun, Gary Monteiro
  • FLOWABLE TISSUE PRODUCTS
    Publication number: 20170086962
    Abstract: The present disclosure provides tissue fillers. The tissue fillers can include a plurality of tissue particles formed from acellular tissue matrix fragments. The tissue fillers can be used to fill tissue sites, such as voids formed after tissue resection.
    Type: Application
    Filed: December 13, 2016
    Publication date: March 30, 2017
    Applicant: LifeCell Corporation
    Inventors: Mark Hayzlett, Ivis Munoz, Nimesh Kabaria, Joshua Czeczuga
  • DEVICE FOR TENDON AND LIGAMENT TREATMENT
    Publication number: 20170071723
    Abstract: Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include acellular arterial tissue matrices that facilitate regrowth of the damaged tissue.
    Type: Application
    Filed: November 3, 2016
    Publication date: March 16, 2017
    Applicant: LifeCell Corporation
    Inventors: Wenquan Sun, Gary Monteiro
  • Vacuum platen tissue planing apparatus
    Patent number: 9594004
    Abstract: Devices and methods for processing animal or human tissue are provided. The devices may include a vacuum surface to secure the tissue in place and an apparatus for removing fat or other material from the tissue. The apparatus can include one or more blades and/or a fluid jet system.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: March 14, 2017
    Assignee: LifeCell Corporation
    Inventors: Michael Alan Fry, Jeremy Howe-Smith
  • Methods for localized modification of tissue products
    Patent number: 9592254
    Abstract: Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating select portions of a tissue matrix with a cross-linking agent and/or a proteolytic enzyme to produce a tissue matrix with variable mechanical and/or biological properties.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: March 14, 2017
    Assignee: LifeCell Corporation
    Inventors: Gary Monteiro, Christopher T. Wagner, Neil L. Rodriguez, Aubrey Irene Delossantos
  • Enzyme-activated collagen and tissue matrices
    Patent number: 9592278
    Abstract: Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include enzyme-activated acellular tissue matrices that facilitate regrowth of the damaged tissue.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: March 14, 2017
    Assignee: LifeCell Corporation
    Inventors: Wenquan Sun, Xiaohua Yu
  • ENZYME-ACTIVATED COLLAGEN AND TISSUE MATRICES
    Publication number: 20170065743
    Abstract: Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include enzyme-activated acellular tissue matrices that facilitate regrowth of the damaged tissue.
    Type: Application
    Filed: September 1, 2016
    Publication date: March 9, 2017
    Applicant: LifeCell Corporation
    Inventors: Wenquan Sun, Xiaohua Yu
  • SHEET TISSUE PRODUCTS
    Publication number: 20170056157
    Abstract: The present disclosure provides a tissue product comprising a tissue sheet. The sheet can be formed from a plurality of tissue matrix fragments.
    Type: Application
    Filed: November 15, 2016
    Publication date: March 2, 2017
    Applicant: LifeCell Corporation
    Inventor: Mark Hayzlett
  • NATURAL TISSUE SCAFFOLDS AS TISSUE FILLERS
    Publication number: 20170049929
    Abstract: Tissue fillers derived from decellularized tissues are provided. The tissue fillers can include acellular tissue matrices that have reduced inflammatory responses when implanted in a body. Also provided are methods of making and therapeutic uses for the tissue fillers.
    Type: Application
    Filed: November 7, 2016
    Publication date: February 23, 2017
    Applicant: LifeCell Corporation
    Inventors: Hui Xu, Wenquan Sun, Hua Wan, Rick T. Owens
  • Breast prostheses, methods of manufacturing breast prostheses, and methods of treatment using breast prostheses
    Patent number: 9549812
    Abstract: Improved breast prostheses, methods of making breast prostheses, and methods of treatment using such breast prostheses are described.
    Type: Grant
    Filed: January 10, 2013
    Date of Patent: January 24, 2017
    Assignee: LifeCell Corporation
    Inventors: Dhanuraj Shetty, Aaron Barere, Evan Friedman, Melissa Richter Bowley, Timothy Roock
  • Flowable tissue products
    Patent number: 9549805
    Abstract: The present disclosure provides tissue fillers. The tissue fillers can include a plurality of tissue particles formed from acellular tissue matrix fragments. The tissue fillers can be used to fill tissue sites, such as voids formed after tissue resection. The disclosure also includes methods of treating tissue using the tissue fillers. The tissue particles can each be formed of tissue fragments having certain sizes.
    Type: Grant
    Filed: December 18, 2012
    Date of Patent: January 24, 2017
    Assignee: LifeCell Corporation
    Inventors: Mark Hayzlett, Ivis Munoz, Nimesh Kabaria, Joshua Czeczuga
  • Tissue transfer apparatus
    Patent number: D795420
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: August 22, 2017
    Assignee: LifeCell Corporation
    Inventors: Joseph Rimsa, Brian J. Domecus