Patents Assigned to Lifecell
  • Tissue-based drain manifolds
    Patent number: 10363343
    Abstract: Disclosed herein are tissue-based drain manifolds comprising partially or completely decellularized tissue that has been processed to form tubes, columns, sheets, or other shapes and which are useful for managing the drainage of fluid and/or the administration of negative pressure at an implant site in a patient. The manifolds can be implanted in a patient and provide a natural scaffold in which native cells from surrounding tissue can migrate and proliferate, thereby avoiding the need to remove the implanted manifolds after drainage is complete.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: July 30, 2019
    Assignee: LifeCell Corporation
    Inventors: Wenquan Sun, Nathaniel Bachrach, Mark Hayzlett
  • BREAST TREATMENT DEVICE
    Publication number: 20190201580
    Abstract: The present disclosure provides devices for treating breasts. The devices (100) include a sheet of acellular tissue matrix having a predefined shape that allows for complete or enhanced coverage of an anterior portion of a breast implant or tissue expander or to support an implant and/or surrounding tissues. The sheet includes curved upper and lower borders or edges.
    Type: Application
    Filed: August 31, 2017
    Publication date: July 4, 2019
    Applicant: LifeCell Corporation
    Inventors: Aaron Barere, Sangwook Park, Kai-Roy Wang
  • Method for preparing collagen-based materials
    Patent number: 10322835
    Abstract: The present disclosure provides a variety of methods and compositions useful for making, sterilizing, and preserving tissues. The disclosure also features the acellular tissue matrices made by the methods.
    Type: Grant
    Filed: August 26, 2015
    Date of Patent: June 18, 2019
    Assignee: LifeCell Corporation
    Inventors: Wendell Sun, Jerome Connor, Qing-Qing Qiu, Rick T. Owens
  • Systems and methods for medical device control
    Patent number: 10314955
    Abstract: Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure. Systems, devices, and methods of the present disclosure control fluid delivery to and from a medical device, including devices for tissue processing and cleaning.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: June 11, 2019
    Assignee: LifeCell Corporation
    Inventors: Evan Friedman, Israel James Jessop, Kai-Roy Wang, Aaron Barere, Brendan P. Collins, Derek Hugger, Christopher Labak, Scott Woodruff
  • Flowable tissue matrices
    Patent number: 10314861
    Abstract: Disclosed herein are flowable tissue matrix compositions comprising small pieces of partially or completely decellularized tissue suspended in a gelatinized tissue or gelatin gel comprising partially or completely decellularized tissue or synthetic gelatin. The flowable tissue matrix compositions can contain factors that promote or enhance native cell migration, proliferation, and/or revascularization after implantation into a subject. Also disclosed are methods of making and using the flowable tissue matrix compositions. The compositions can be implanted into a tissue in need of repair, regeneration, healing, treatment, and/or alteration, and can promote or enhance native cell migration, proliferation, and/or revascularization.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: June 11, 2019
    Assignee: LifeCell Corporation
    Inventor: Wenquan Sun
  • Methods of removing alpha-galactose
    Patent number: 10307510
    Abstract: Tissue products lacking a desired percentage of immunogenic epitopes, such as galactose alpha-1,3 galactose epitopes, are provided. Methods of making and using the tissue products are also provided.
    Type: Grant
    Filed: November 4, 2014
    Date of Patent: June 4, 2019
    Assignee: LifeCell Corporation
    Inventors: Hui Xu, Li Ting Huang, Hua Wan, Rick T. Owens, Nathaniel Bachrach
  • Tissue matrices and methods of treatment
    Patent number: 10307237
    Abstract: Methods, systems, and compositions for treatment are provided. The methods can be used to stretch and completely or nearly completely wrap a composition around an implant or tissue expander. The systems can be used to protect an implant or tissue expander by completely or nearly completely wrapping a composition around the implant or tissue expander. The compositions can be used to completely or nearly completely wrap around an implant or tissue expander to provide support and protection to the implant or tissue expander.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: June 4, 2019
    Assignee: LifeCell Corporation
    Inventors: Kai-Roy Wang, Sangwook Park, Aaron Barere
  • Device for harvesting, processing and transferring adipose tissue
    Patent number: 10300183
    Abstract: The present disclosure provides devices and methods for harvesting and processing tissue from patients for grafting. The devices can include a tissue collection chamber for ascetically collecting, processing, and/or re-implanting adipose tissue.
    Type: Grant
    Filed: February 2, 2016
    Date of Patent: May 28, 2019
    Assignee: LifeCell Corporation
    Inventors: Sangwook Park, Jerome Connor, Aaron Barere
  • Systems and methods for tissue sterilization
    Patent number: 10293064
    Abstract: Systems and methods for sterilization of tissue are provided.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: May 21, 2019
    Assignee: LifeCell Corporation
    Inventors: Qing-Qing Qiu, Jerome Connor
  • Systems and methods for tube management
    Patent number: 10286122
    Abstract: Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure.
    Type: Grant
    Filed: October 21, 2016
    Date of Patent: May 14, 2019
    Assignee: LifeCell Corporation
    Inventors: Christopher Locke, James Seddon, Benjamin A. Pratt, Evan Friedman, Aaron Barere
  • DEVICES AND METHODS FOR AUTOMATED FILLING AND DISPENSING OF ADIPOSE TISSUE WITH CONTROL OF SHEAR
    Publication number: 20190117202
    Abstract: Devices, systems, and methods for tissue transfer are disclosed that can allow control of transfer speed. The devices use positive and negative pressure to advance a plunger (322) into or out of a body (311) of the device. A pressure regulator may be used to control the applied pressure. Maintaining transfer speed within acceptable ranges and/or controlling pressure or shear forces on tissues can improve the viability of certain types of tissue.
    Type: Application
    Filed: November 1, 2016
    Publication date: April 25, 2019
    Applicant: LifeCell Corporation
    Inventors: Kai-Roy Wang, Christopher Locke, Dennis Y. Lee, Evan J. Friedman, Israel Jessop, Sangwook Park
  • Device and method for treatment of incision or hernia
    Patent number: 10238480
    Abstract: Devices and methods for treating an abdominal incision or hernia are described. An implant for the restoration or prophylactic treatment of an abdominal wall comprises an elongate element and at least one sheet connected to the elongate element along a longitudinal axis of the elongate element. The elongate element is positioned along the line of incision, and the at least one sheet is secured to the abdominal muscles surrounding the incision.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: March 26, 2019
    Assignee: LifeCell Corporation
    Inventor: John R. Harper
  • Method for enzymatic treatment of tissue products
    Patent number: 10207025
    Abstract: Methods for treating tissue matrices and tissue matrices produced according to the methods are provided. The methods can include treating a tissue matrix with a proteolytic enzyme to produce a desired pliability of the tissue matrix and/or to control the immunogenicity of the tissue matrix. The methods can also comprise performing an assay to determine if contacting the at least one collagen-containing tissue matrix with a proteolytic enzyme has altered the at least one collagen-containing tissue matrix to reduce a human immune response to the tissue matrix. The methods can comprise treatment with alcalase under conditions controlled to produce a desired pliability without unacceptable alteration in collagen structure.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: February 19, 2019
    Assignee: LifeCell Corporation
    Inventors: Yi Chen, Kai-Roy Wang, Patrick Leamy, Hui Xu, Nimesh Kabaria
  • Tissue processing device and associated systems and methods
    Patent number: 10184111
    Abstract: Tissue processing devices are provided. The tissue processing devices can be used to process and transport tissue in a closed and continuous environment. The devices can be used for adipose tissue transfer, including autologous fat grafting.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: January 22, 2019
    Assignee: LifeCell Corporation
    Inventors: Kai-Roy Wang, Aaron Barere, Evan Friedman, Sangwook Park
  • Dry platelet composition
    Patent number: 10179150
    Abstract: The invention features a dry platelet composition and methods of making and using the freeze-dried platelet composition.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: January 15, 2019
    Assignee: LifeCell Corporation
    Inventors: Christopher T. Wagner, Jerome Connor, John R. Harper
  • NATURAL TISSUE SCAFFOLDS AS TISSUE FILLERS
    Publication number: 20190009003
    Abstract: Tissue fillers derived from decellularized tissues are provided. The tissue fillers can include acellular tissue matrices that have reduced inflammatory responses when implanted in a body. Also provided are methods of making and therapeutic uses for the tissue fillers.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 10, 2019
    Applicant: LifeCell Corporation
    Inventors: Hui Xu, Wenquan Sun, Hua Wan, Rick T. Owens
  • Enzyme-activated collagen and tissue matrices
    Patent number: 10159722
    Abstract: Devices and methods for treating defects in connective tissue are provided along with methods for making such devices. The devices can include enzyme-activated acellular tissue matrices that facilitate regrowth of the damaged tissue.
    Type: Grant
    Filed: September 1, 2016
    Date of Patent: December 25, 2018
    Assignee: LifeCell Corporation
    Inventors: Wenquan Sun, Xiaohua Yu
  • ELASTASE TREATMENT OF TISSUE MATRICES
    Publication number: 20180311410
    Abstract: A method of producing a modified acellular tissue matrix (mATM) from an acellular tissue matrix (ATM), where the mATM has a reduced stretchiness relative to the ATM, without substantially compromising its associated structural or functional integrity. The method includes providing an acellular tissue matrix (ATM) and exposing the ATM to elastase for a period of time.
    Type: Application
    Filed: July 6, 2018
    Publication date: November 1, 2018
    Applicant: LifeCell Corporation
    Inventor: Wendell Sun
  • SHEET TISSUE PRODUCTS
    Publication number: 20180296317
    Abstract: The present disclosure provides a tissue product comprising a tissue sheet. The sheet can be formed from a plurality of tissue matrix fragments.
    Type: Application
    Filed: June 20, 2018
    Publication date: October 18, 2018
    Applicant: LifeCell Corporation
    Inventor: Mark Hayzlett
  • Canister-type device for tissue processing
    Patent number: D851777
    Type: Grant
    Filed: January 30, 2017
    Date of Patent: June 18, 2019
    Assignee: LifeCell Corporation
    Inventors: Aaron Barere, Evan J. Friedman, Brendan P. Collins, Derek Hugger, Christopher Labak, Scott Woodruff