Abstract: A vehicle lamp assembly is provided with at least one light source having an optical axis. A lens body a first body segment having a light-collection surface positioned adjacent the light source and from the light-collecting face to a first total-internal-reflection (TIR) surface. A middle body segment extends from the first TIR surface to a second TIR surface. A second body segment extends from the second TIR surface to a light emission surface defining an output optical axis. Light propagates in each of the first, middle and second segments in a generally collimated light path.

Abstract: A lighting device assembly includes a first optic member having a light entry side and a light exit side, is arranged to receive light from a light source and is configured to emit light in a light beam or pattern having a peripheral edge portion. An aperture member has an optical opening arranged in alignment with the first optic member to pass a portion of the light from the first optic member. The aperture member has a plurality of surface regions surrounding the optical opening. Each surface region is configured to reflect a different respective section of the peripheral edge portion of the light beam or pattern toward the light exit side of the first optic member.

Abstract: A system and method for controlling a multiplicity of luminaries connected to a single wire pair. The luminaries contain minimum circuitry to allow dimming and color tuning by pulses on the wire pair without the need for a separate control wire or control communication bus or network. A single luminary can be color tuned to many different colors as well as dimmed and turned on and off. A driver module drives the wire pair and receives commands over a network The driver module contains a pulse generation circuit that generates and applies pulses to the two-wire output. The amplitude of some the pulses control color of the luminary by selecting different LEDs in the luminary to light, while other pulses control brightness.

Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.

Abstract: A device for a wireless device control system for controlling lighting devices is disclosed. The device can include a wireless transceiver, a power loss detection circuit, a communication loss detection circuit, a power monitoring circuit, and an output circuit. The device is configurable to provide a preselected communication loss action upon detecting communication loss, a preselected power loss action upon detecting power loss, and a preselected load power fault action upon detecting a load power fault.

Abstract: Methods of sorting T lymphocytes in a microfluidic device are provided. The methods can include flowing a fluid sample comprising T lymphocytes through a region of a microfluidic device that contains an array of posts. The array of posts can be configured to have a critical size (Dc) that separates activated T lymphocytes from naïve T lymphocytes. Also provided are microfluidic devices having an array of posts configured to separate activated T lymphocytes from naïve T lymphocytes, compositions enriched for T lymphocytes, particularly activated T lymphocytes that are known to be reactive to an antigen of interest, and methods of treating subjects suffering from a pathogenic disorder or cancer by administering such compositions.

Abstract: In accordance with various embodiments, lighting systems features multiple inter-connectable light panels each having multiple light-emitting elements thereon. One or more of the light panels features one or more connectors, and associated conductors, for the transmission of power, communication signals, and/or control signals.

Abstract: Methods are described herein for isolating clonal populations of T cells having a defined genetic modification. The methods are performed, at least in part, in a microfluidic device comprising one or more sequestration pens. The methods include the steps of: maintaining individual T cells (or precursors thereof) that have undergone a genomic editing process in corresponding sequestration pens of a microfluidic device; expanding the T cells into respective clonal populations of T cells; detecting, in one or more T cells of each clonal population, the absence of a cell surface marker that was present in the individual T cells (or precursors thereof); and detecting, in one or more T cells of each clonal population, the presence of a first nucleic acid sequence that is indicative of the presence of an on-target genome edit in the clonal population of T cells. Also described are compositions comprising one or more clonal populations of T cells isolated according to the methods disclosed herein.

Abstract: A high-bay luminaire includes an upper housing having an outer wall with an outer wall having a plurality of first heat fins extending therefrom, and an interior surface defining an interior compartment with an angled wall; a base connected to the upper housing; a light emitter connected to the base; a lens connected to the base and positioned below the light emitter; and a driver connected to the angled wall by a driver bracket and positioned adjacent the interior surface.

Abstract: A lighting assembly with a single edge lit optical configuration produces various asymmetric light distributions which provide targeted control of light output with peak intensity that is non-normal to the light guide output face. The compact form factor of the lighting assembly embodiments having narrow width are particularly well-suited for use in linear lighting applications requiring suspended, surface and recessed installations typically used to illuminate walls, floors and/or ceilings. The lighting assembly can also be selectively configured and oriented during assembly and installation to achieve various lighting distributions. Optical components within the lighting assembly are typically positioned and retained in optical alignment with internal support features of a linear housing.

Abstract: A linear lighting assembly is disclosed which produces tailored light distributions valuable in many illumination applications. The linear lighting assembly comprises a unique light scattering optical element within a single edge lit linear lighting module housing configured to fit within a linear light fixture housing, both housings capable of being fabricated in a continuous extrusion process and cut to length as need for specific linear lighting assembly lengths. Light distributions attainable using the invention include, but are not limited to, symmetric and asymmetric bi-lobed “batwing” distributions for wide area direct and indirect lighting, and tilted or asymmetric distributions for perimeter lighting. It is also possible to achieve more rounded and symmetric distributions by an additional diffuser as a cover lens. The invention is particularly well-suited for linear lighting fixtures that are surface mounted, suspended or recessed.

Abstract: A luminaire structure, comprises a plurality of housing segments, each with at least one lighting zone, and configured to be assembled to form a support structure defining at least one panel supporting zone for supporting at least one acoustic panel removably attached thereto, wherein each of the lighting zones in the support structure is oriented to be adjacent the at least one acoustic panel, and operable to receive a lighting module to deliver light to an interior space.

Abstract: A lighting device system includes a lighting device module having a module housing configured to be selectively inserted through an opening in a panel or a base. Driver electronics are configured to be electrically coupled to the lighting device module. A heat sink member is located adjacent the opening in the panel or the base. A movable biasing device has a first position to apply a bias force on the module housing, pressing the module housing toward the heat sink member to increase thermal transfer. The moveable biasing device has a second position to provide improved access to the driver electronics through the opening in the panel or base relative to the first position. The movable biasing device is selectively moveable from the first position to the second position, or from the second position to the first position.

Abstract: A trim member for a lighting device module includes an annular body having a first end portion that is connectable to a housing of the lighting device module and has a light receiving opening, and a second end portion opposite to the first end portion. The second end portion has a light emitting opening and is configured to be positioned outside of the housing of the lighting device module. A first curved or tapered surface extends from the light receiving opening toward the light emitting opening, and has a diameter that increases toward the light receiving opening. A second curved or tapered surface extends from the first curved or tapered surface to the light emitting opening, and has a diameter that increases toward the light emitting opening.

Abstract: A light fixture with a single edge lit optical assembly produces various light distributions which provide targeted control of light output with peak intensity that is non-normal to the light guide output face. The compact form factor and modular design of the light fixture embodiments having narrow width are particularly well-suited for use in linear lighting applications requiring suspended, surface and recessed installations typically used to illuminate walls, floors and/or ceilings. The light fixture can also be selectively configured and oriented during assembly and installation to achieve various lighting distributions. Optical components within the light fixture are typically positioned and retained in optical alignment with internal support features of a linear housing. The optical assembly typically includes LED board, light guide, and one or more reflective surfaces. Additionally an optically transmitting component further provides a fixture assembler a range of design choices.

Abstract: In biosciences and related fields, it can be useful to study cells in isolation so that cells having unique and desirable properties can be identified within a heterogenous mixture of cells. Processes and methods disclosed herein provide for encapsulating cells within a microfluidic device and assaying the encapsulated cells. Encapsulation can, among other benefits, facilitate analyses of cells that generate secretions of interest which would otherwise rapidly diffuse away or mix with the secretions of other cells.