Abstract: The invention provides methods for isolating RNA from the soluble fraction of urine. The methods can be used for detecting the presence or absence of an RNA, or quantifying the amount of an RNA. The methods are useful for diagnosing an individual suspected of having a disease by detecting the level of RNA associated with the disease in the soluble fraction of urine. The methods are also useful for prognosing an individual diagnosed with a disease by detecting the level of RNA associated with the disease in the soluble fraction of urine.

Abstract: Engineered Cas9 systems are disclosed herein.

Abstract: A multi-factor safe locking system for use in firearm storage, wherein the factors comprise a user's provided key, a user's biometric data, and a user's provided code. In some embodiments, the multi-factor safe locking system requires the near-simultaneous entry of two users, or dual consent of the two users to enter at least two unique keys, at least one form of biometric data from each user, and at least two unique codes, wherein each user supplies their own unique code to access the safe's contents. In further embodiments, a safe locking system includes a further factor of a result from a blood alcohol test.

Abstract: Systems and methods are disclosed herein for building contextual transcripts. A computing system may receive a textual transcript of a meeting that contains a variety of statements made by various attendees of the meeting, select the first statement made during the meeting, and determine which meeting attendee made the statement. A machine learning model corresponding to the particular attendee that has been trained using previously received statements by the particular attendee may be used on the utterance to determine the tone of the utterance. That tone may be recorded within the transcript and this process may be repeated for each utterance to build a contextual transcript.

Abstract: Systems, devices, and methods are provided for measuring fluid flow across a pump used in a system for precisely and accurately metering fluid. The systems, devices, and methods can use contactless approaches to measure the properties of the fluid being pumped. The measured properties can be used to precisely and accurately determine the flow rate through the pump.

Abstract: Disclosed embodiments may include a system for generating custom content. The system may generate a first webpage comprising first feature(s). The system may transmit the first webpage for display via a graphical user interface (GUI) of a user device. The system may iteratively, until a predetermined threshold is achieved: receive data corresponding to a first user; generate, by an encoder, encoded data based on the data; generate, by a decoder, second feature(s) based on the encoded data; modify the first webpage to generate a second webpage comprising the second feature(s); transmit the second webpage for display via the GUI of the user device; receive user feedback associated with the second webpage; and determine whether the user feedback exceeds the predetermined threshold. Responsive to the predetermined threshold being achieved, the system may transmit the latest version of the second webpage without requesting additional user feedback.

Abstract: Prior to associating with a wireless network, a wireless device receives from a network access point, a message containing information identifying (i) identity of the network and (ii) network policies; retrieves the information from the message; based on the network identity, determines whether a network attributes record for the network already exists in the device. If not, the device creates a temporary network attributes record for the network. Based on the network policies, the device attempts to associate to and authenticate the network. After successfully associating to and authenticating the network, the device determines whether the network attributes record for the network has expired. If not, the device renews the network attributes record and implements the network policies stored in the network attributes record If the network attributes record has expired, then the device deletes the network attributes record and implements default network policies for the wireless network.

Abstract: A coding and modulation apparatus and method are presented. The apparatus comprises an encoder that encodes input data into cell words, and a modulator that modulates said cell words into constellation values of a non-uniform constellation. The modulator is configured to use, based on the total number M of constellation points of the constellation and the code rate, a non-uniform constellation from one or several groups of constellations each comprising one or more constellations.

Abstract: A transaction record is created showing a purchase transaction of a customer. A CV profile showing a list of items in the transaction obtained from images is also obtained. The items in the transaction record are compared to items on the list. When there is a discrepancy, an action to take is determined.

Abstract: A system and process for restarting a turbomachine includes a shutdown cooldown protection process implemented by a plant level control system or direct control system of the turbomachine. The system and process for restarting ensure rotating components are cooled as expected prior to a unit restart. This system and process for restarting will lockout an ability to restart if an improper cooldown of rotating components is detected. If this lockout is enabled, delaying restart for the rotating components to cool naturally is needed, or the operator could decide to force cool the components.

Abstract: In one implementation, a wireless security system premises gateway component includes a first local area wireless communication component adapted to communicate wirelessly with plural wireless security system sensors distributed at a premises; a second local area wireless communication component adapted to communicate wirelessly with a general purpose mobile communications device; a communications interface component adapted to communicate with a wide area communications network that is located remotely of the premises; a security system controller component adapted to communicate with the general purpose mobile communications device to provide state information regarding the security system and to provide control inputs to the security system; and a single gateway housing configured and sized to house the first local area wireless communication component, the second local area wireless communication component, the communications interface component, and the security system controller.

Abstract: Embolization particles can be safely delivered to the left gastric artery of a patient by introducing the distal end of a catheter in the patient's left gastric artery, inflating a balloon located near the distal end of the catheter so that the balloon prevents blood from flowing through the left gastric artery, and injecting a mixture of particles and contrast agent into the proximal end of the catheter so that they flow through the catheter. In addition, a path is provided for blood to flow into the catheter through an opening in the sidewall of the catheter at a position that is proximal to the balloon, and out through the distal end of the catheter. This blood flow helps to carry the particles along to their destination in the distal portion of the left gastric artery. The particles are also prevented from flowing into portions of the patient's artery system that are proximal of the balloon.

Abstract: A bicycle with an electric pedal assist motor capable of driving a chainring independent of cranks includes wheel speed sensors and crank cadence sensors. The wheel speed sensors and the crank cadence sensors measure wheel speed and crank cadence, respectively, and provide the measured wheel speed and crank cadence to controller of the bicycle. The controller activates motor overdrive based on the measured wheel speed and/or the measured crank cadence.

Abstract: The present disclosure relates to a system and method (10) for monitoring a set-up for manufacture and/or setting up for manufacture and/or tearing down after manufacture of a biopharmaceutical product. The method comprises: processing (S2, S3, S4) at least one image of a scene comprising the set-up for manufacture of the biopharmaceutical product. The processing of the at least one image comprises performing (S2) a first process on the at least one image for classifying first objects in the image, said first objects being devices such as clamps, pumps, valves and/or sensors and/or any other bio processing equipment. The first process comprising identifying, localizing and classifying the first objects in the image. A second process is performed (S3) on the at least one image for identifying and localizing connections in the images.

Abstract: Introduced here is an attachable unit that connects to a base unit through a snap-fitting mechanism. The attachable unit can include a top housing structure and a bottom housing structure that are ultrasonically welded together. The top housing structure can include the toe portion that is integral with remaining portions of the top housing structure, where the toe portion is configured to provide the snap-fit with the base unit.

Abstract: Disclosed herein are systems and methods for a system for authorizing proxy number token requests. The system may comprise a memory storing instructions and at least one processor configured to execute instructions to perform operations. These operations may comprise receiving a first request to use a proxy number token to complete a first action associated with a first entity; authorizing the first request; receiving a second request to use the proxy number token to complete a second action associated with a second entity; determining a modifiable relationship data binding associated with the first and second entities, the modifiable relationship data binding comprising multiple parameters; determining that the second request satisfies the parameters; and authorizing the second request based on a determination that the second request satisfies the parameters.

Abstract: A torque enhancement device having torque enhancement member(s) with each having an exterior (preferably bi-symmetric or essentially bi-symmetric) surface configuration with parallel, longer side walls extending in a Y-axis direction and shorter side walls extending in an X-axis direction and corner recesses positioned between ends of adjacent longer and shorter side walls, and with some embodiments of the invention featuring a torque enhancement device having a hole extending in a Z-axis direction. A fastener assembly is also provided that includes one or more torque enhancement devices as well as methods for utilization of the torque enhancement device or utilization or assemblage of an assembly including a torque enhancement device.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-7 or IL-21.

Abstract: An enhanced integration of spreadsheet environments and external environments is disclosed herein that allows users to enter non-native statements directly into the cells of a worksheet so that external resources can be applied with respect to their values. In addition, a security model is disclosed whereby external functions referenced in the cells of a worksheet are executed in the context of a runtime environment that is secured apart from the spreadsheet application that hosts the worksheet. Various enhancements to the user experience are also disclosed that allow users to enter non-native statements in line with respect to the functional syntax that forms the basis of spreadsheet formulas.