Abstract: Disclosed herein relates to the biological activities and preparation of 5-(2-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)ethyl)-5-azaspiro[2.4]-heptan-7-ol (Compound A) stable crystalline form (Compound A-Xln); its tablet (Compound A-Xln tablet); its phosphoric acid salt (Compound A-P) and phosphoric acid salt stable crystalline form (Compound A-P-Xln); as well as its enantiomers (Compound R-A, Compound S-A). Furthermore, their anti-cancer activities, stabilities, chirality, dissolutions and treatment indications have also been investigated.

Abstract: A cooling tower system including a cooling tower housing, a basin and spray nozzles within the cooling tower housing, and a supply pipe configured to transmit a fluid from the basin to the spray nozzles. A filter loop is coupled to the supply pipe. A filter assembly connected in-line to the filter loop.

Abstract: The application discloses an eartip, an earphone device, an earphone housing and a hearbud housing device. The eartip can include an outer portion, an inner portion, and an encapsulated volume formed by the inner and outer portion, wherein the outer portion is designed to contact the ear canal, and wherein the inner portion is designed to fit upon a stent. In an alternative embodiment, the airtip can include an inverted body, wherein when the inverted body is at least partially folded on itself the inverted body is arranged to include a bulbous region sized for insertion in an ear canal, a cavity internal to the bulbous region that holds a gas, where increasing pressure on the bulbous region releases a portion of the gas.

Abstract: A lower leg support device for a vehicle seat may have a first cushion carrier, a second cushion carrier, which is connected in an articulated manner to the first cushion carrier, and a coupling gear for transferring the first cushion carrier and the second cushion carrier from a non-use position to a use position. The coupling gear is able to be driven by a drive device. A vehicle seat may have the lower leg support device.

Abstract: A method to demetal and de-ash oil feedstock. The method includes adding direct steam and sulfuric acid to oil feedstock to form acid treated oil, the sulfuric acid to strip the oil feedstock of metals, adding de-emulsifier to the acid treated oil feedstock to aid in phase separation, and settling the acid treated oil feedstock to separate into clarified oil, water, and a rag layer. The method includes centrifuging the clarified oil with a centrifuge running in a 3 phase configuration to remove water and solids from the clarified oil, and ensuring proper temperature and adding triethanol amine (TEA) to the centrifuged clarified oil to flocculate asphaltenes in the centrifuged clarified oil, creating TEA treated oil. The method includes centrifuging the TEA treated oil with a centrifuge running in a 2 phase configuration to remove the asphaltenes from the TEA treated oil and create marine fuel.

Abstract: In one aspect, a magnetic field current sensor includes an annihilation detector. The annihilation detector includes an annihilation bridge that includes magnetoresistance elements. The annihilation detector also includes a current bridge that includes at least two of the magnetoresistance elements, a first comparator configured to compare an output signal from the annihilation bridge and a second comparator configured to compare an output signal from the current bridge. An output of the annihilation detector indicates whether an annihilation exists in one or more of the magnetoresistance elements using at least one of the outputs signals of the first and second comparators.

Abstract: A computing system measures an amount of carbon that is emitted as a consequence of the execution of individual application processes of an operation. The computing system can then leverage these measurements to modify how the application processes are run. In operation, the computing system deploys an application process in a container of a particular worker node of a cluster in a container orchestration platform. The technology further deploys an agent (e.g., a daemon) on all of the worker nodes of the cluster, including the particular worker node. The agent includes an energy-managing mechanism that is given privileges to measure the amount of energy consumed by the application process within the particular node. The computing system can use this energy measure, together with applicable carbon intensity information, to compute the amount of carbon emitted by the application process.

Abstract: One example provides a computing system comprising a depth sensor comprising a plurality of pixels, and a storage machine holding instructions executable by a logic machine to, for each pixel, make K phase measurements to form a set of noisy phase measurements, determine a location at which a projection line that passes through the set of noisy phase measurements in a K-dimensional phase space passes through a lower dimensional plane, the projection line being parallel to a noise free phase evolution line, compare the location to a plurality of independent terms of a predetermined matrix of points in the lower dimensional plane, locate a corresponding set of noiseless phase orders by using a selected set of independent terms to reference a look-up table, determine a distance value for the pixel based upon the corresponding set of noiseless phase orders, and output the distance value for the pixel.

Abstract: The present invention is a specially prepared fibrin foam, and a method of (and equipment for) making it, which is flexible, contains either open cells, closed cells or both, and having individual cell diameters between 0.001 and 2 mm. Typical ratios of reactants, to give the desired foam characteristics, include 50 cc (45-55 cc) of whole blood (prior to separation to the plasma component) with the subsequent addition thereto of 2 ml (1.5-2.5 ml) 3% hydrogen peroxide, 5000 units (4500-5500 units) thrombin and 1 gm (0.9-1.1 g) calcium chloride in 3 cc (2-4 cc) water. The present invention also includes specialty vessels and constructs, namely, automated, or semi-automated inner containers for the non-blood reactants, and a custom outer separation vessel having a punted based with an annular base lip as well as an upper tube shape tapering inward towards its top annular opening.

Abstract: A machine or group of machines for monitoring location of at least one of a vehicle or freight carried by the vehicle includes a communications interface configured to communicate electronic signals including a location request signal including data representing a request for information regarding the location of the vehicle or the freight carried by the vehicle, and a correlation logic in the machine or group of machines configured to correlate, by a CPU, the vehicle or the freight carried by the vehicle to a communications device.

Abstract: Ammonia oxidizing microorganism preparations for delivery to the intranasal system, kits including ammonia oxidizing preparations for delivery to the intranasal system, and devices for administering ammonia oxidizing preparations to the intranasal system are provided. Methods of introducing ammonia oxidizing microorganisms to the intranasal system are provided. Methods of treating disorders, including neurological disorders, nasal or sinus disorders, and inflammatory disorders, with ammonia oxidizing microorganism preparations are provided.

Abstract: A pacemaker system includes a drive-sense circuit (DSC) operably coupled to a pacemaker lead. The DSC generates a pace signal including electrical impulses based on a reference signal. The DSC provides the pace signal via the pacemaker lead to an electrically responsive portion of a cardiac conductive system of a subject to facilitate cardiac operation of a cardiovascular system of the subject. The DSC senses, via the pacemaker lead, cardiac electrical activity of the cardiovascular system of the subject that is generated in response to the pace signal and electrically coupled into the pacemaker lead and generates a digital signal that is representative of the cardiac electrical activity of the cardiovascular system of the subject that is sensed via the pacemaker lead. The DSC provides digital information to one or more processing modules that includes and/or is coupled to memory and that provide the reference signal to the DSC.

Abstract: Provided is a method of estimating temperature in a device including a main printed circuit board (PCB), a protection and control module (PCM), and one or more batteries electrically connected to the PCM. The method includes sensing a temperature of the PCB, via a PCB temperature sensor and sensing a temperature of the PCM via a PCM temperature sensor. The method also includes estimating a temperature of at least one of the batteries based on (i) the temperature determined via the PCB temperature sensor and (ii) the temperature determined via the PCM temperature sensor.

Abstract: A cargo space cover for a vehicle, the cargo space cover comprising a body comprising a first panel, a second panel, a tote bottom, a first tote wing, and a second tote wing; and at least one coupling portion. The cargo space cover operates in a cover configuration and a tote configuration. While the at least one coupling portion of each the first edge of the first panel and the second edge of the second panel each couple to an a first side wall of the interior of the vehicle and a second side wall of the interior of the vehicle, the cargo space cover is held in the cover configuration. While two of the first panel, the second panel, and the tote bottom operably couple to each of the first tote wing and the second tote wing the cargo space cover is held in the tote configuration.

Abstract: A workstation includes a dashboard for a vehicle having a recess on an upper surface, a first display screen extending from the dashboard, and a second display screen that is deployable between a stowed position within the recess in the dashboard and an extended deployed position aligned proximate to the first display screen. A control arm operatively couples the first display screen with the second display screen, wherein the control arm pivots about a pivot axis to deploy the second display screen proximate to the first display screen. The workstation has a deployable desk that pivots between a stowed position proximate to the dashboard and an extended deployed position forward of the dashboard, wherein the desk in the stowed position covers the second display screen.

Abstract: Ultraviolet (UV) absorbing inks and films for surfaces such as glass and/or plastic are provided that include patterns visible to avian eyes, but invisible to a human at least ten feet away. Such invention is aimed at reducing the number of window strikes that result in bird deaths. A formulation may include a binder, a carrier. A formulation may include a base configured to dissolve and solubilize the binder such that it can be applied to the carrier. A formulation may include at least one of an ultraviolet (UV)/visible (VIS) absorbing (UAC) component and a UV/VIS reflective (URC) component.

Abstract: Four genes, A622, NBB1, PMT, and QPT, can be influenced for increasing nicotinic alkaloid levels in Nicotiana plants, as well as for synthesizing nicotinic alkaloids in non-nicotine producing plants and cells. In particular, overexpressing one or more of A622, NBB1, PMT, and QPT may be used to increase nicotine and nicotinic alkaloid levels in tobacco plants. Non-nicotine producing cells can be engineered to produce nicotine and related compounds by overexpressing A622 and NBB1.

Abstract: An interface circuit that can operate in toggle mode at data high transfer rates while reducing the self-induced noise is presented. The high speed toggle mode interface supplies a data signal to a data line or other transfer line by a driver circuit. The driver circuit includes a pair of series connected transistors connected between a high supply level and a low supply level, where the data line is supplied from a node between the two transistors. A resistor is connected between one or both of the transistors and one of the supply levels, with a capacitor connected between the low supply level and a node between the resistor and the transistor. The resistor helps to isolate the transistor from the supply level while the capacitor can act as current reservoir to boost the current to the transistor during data transition, reducing the noise seen by the voltage supply.

Abstract: Wireless devices may perform modified carrier sense multiple access (CSMA) techniques in order to increase reliability while maintaining a reasonable latency for communications. The wireless devices may perform listen-before-talk (LBT) techniques using an adaptive transmission threshold (e.g., an adaptive CSMA threshold). The transmission threshold may be compared to a measured signal strength magnitude to determine whether the frequency channel is quiet enough for transmission of a packet. The transmission threshold may be initially set to equal a minimum value. The wireless device may increase the transmission threshold after each instance of LBT failure to allow the wireless device to get progressively more likely to transmit the packet each time LBT fails.

Abstract: A method for extinguishing a flame and terminating thermal runaway in a device powered by a lithium ion battery. The disclosure also provides a system for extinguishing fires generated by lithium ion batteries exhibiting thermal runaway.