Abstract: Embodiments provide swallow-able devices, preparations and methods for delivering therapeutic agents (FAs) within the GI tract such as antibodies (AP-antibodies) or other proteins which neutralize PCSK9 molecules. Many embodiments provide a swallowable device e.g., a capsule for delivering TAs into the intestinal wall (IW). Embodiments also provide TA preparations that are configured to be contained within the capsule, advanced from the capsule into the IW and/or peritoneum and degrade to release the TA into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the IW. Embodiments are particularly useful for delivery of AP-antibodies and related TA's for the treatment of cholesterol, lipid and related conditions where such TAs are poorly absorbed and/or degraded within the GI tract.

Abstract: A system for coordinating that actions taken by multiple apparatuses useful for automatically adjusting tension on a retention member and thereby applying pressure or other forces to an object. Sensors may be used to sense changes associated with the object involved or the environment, and an actuator may be included that automatically rotates a rotating member such as a gear or pulley to automatically adjust tension on the retention member. The adjustments in tension may be made performed automatically and many times per second based on control signals from control logic responsive to the sensors. Individual apparatuses may coordinate their activities according to input received from one or more sensors, and according to a control circuit, or multiple collaborating control circuits. The control circuit(s) may be configured to adapt automatically over time to optimize the overall behavior of the system.

Abstract: A pharmaceutical composition comprises a drug-carrier system having a small-molecule drug of low water solubility such as one or more small molecule integrin agonist adjuvants in a substantially non-aqueous carrier composition that comprises at least one phospholipid, at least one neutral lipid, and at least one pharmaceutically acceptable solubilizing agent. The drug-carrier system, when mixed with an aqueous phase, typically forms a non-gelling, substantially non-transparent liquid dispersion. The composition is suitable for administration by a suitable route, e.g., orally, to a subject in need thereof.

Abstract: A method for identifying a completed lap at a device is disclosed. An example method includes retrieving or defining lap initiation data that can include an initiation location and an initiation orientation. The method also includes retrieving or defining a location variance threshold for the initiation location and an orientation variance threshold for the initiation orientation. The method further includes determining, by a position determining module of the device, a first location of the device associated with a first time. The method also includes determining, by an orientation determining module of the device, a first orientation of the device associated with the first time. The method also includes identifying a lap as completed upon determining that the first location of the device is within the location variance threshold of the initiation location and that the first orientation of the device is within the orientation variance threshold of the initiation orientation.

Abstract: A layered catalyst structure for purifying an exhaust gas stream includes a catalyst support and a rhodium catalyst layer including an atomic dispersion of rhodium ions and/or rhodium atoms adsorbed on an exterior surface of the catalyst support. The catalyst support includes an alumina substrate, a first ceria layer disposed on and extending substantially continuously over the alumina substrate, and a second colloidal ceria layer formed directly on the first ceria layer over the alumina substrate.

Abstract: Methods, apparatus, systems, and articles of manufacture are disclosed to generate synthetic respondent level data. Example apparatus disclosed herein include means for generating a synthetic panel corresponding to a duration of time, the means for generating the synthetic panel to: generate a transition matrix corresponding to a first sub-duration of the duration of time and a second sub-duration of the duration of time; generate, based on the transition matrix, a plurality of synthetic panelists and associated viewing data; remove first ones of the synthetic panelists associated with one or more weights that do not satisfy a threshold to generate the synthetic panel corresponding to the duration of time, the synthetic panel representative of audiences of media presented by a plurality of media devices during the duration of time; and generate synthetic respondent level data based on the viewing data associated with remaining second ones of the synthetic panelists.

Abstract: A paperboard structure includes a paperboard substrate having a first surface and an opposed second surface. A biopolymer coating is applied by extrusion or co-extrusion to at least one of the first surface and the second surface. The biopolymer coating includes an inorganic melt curtain stabilizer, a polylactide resin having a melt flow index, and an organic polymeric chain extender.

Abstract: A system including a lithium-ion battery is provided. The system includes two electrodes, which include an anode and a cathode. The system further includes an electrolyte and a planar separator disposed between the anode and the cathode. The planar separator includes a first planar face, a second planar face, a layer of porous ceramic material coating the first planar face, and lithium deposited upon the layer of porous ceramic material. The lithium is in contact with one of the two electrodes.

Abstract: A device is provided. The device includes mechanically stacked layers. The mechanically stacked layers include a bottom layer and upper layers. Each upper layer includes a transmissive solar cell that converts light energy into electricity. Each upper layer transmits unconverted portions of the light energy towards the bottom layer. The bottom layer includes a solar cell that converts the unconverted portions of the light energy into electricity.

Abstract: A method of video decoding includes creating a candidate list for a current block in a current picture included in a coded video bitstream. The method further includes determining a coding mode for a candidate block associated with the current block. The method further includes determining whether to add, to the candidate list, a vector associated the candidate block based on the determined coding mode. The method further includes reconstructing the current block using at least one candidate from the candidate list.

Abstract: A vehicle air monitoring system includes a housing defining an interior and an inlet. An airflow assembly is disposed within the interior and includes a pump configured to draw an air sample into an airflow passage via the inlet. A detection assembly is in fluid communication with the airflow passage of the airflow assembly. The detection assembly includes a light source configured to illuminate a biochip and a photodetector configured to detect an optical transmission of the biochip based on a photocurrent of the photodetector. A control assembly is in communication with the airflow assembly and the detection assembly. The control assembly is configured to activate the pump to draw the air sample into the airflow passage, compare the photocurrent by the photodetector with a predefined baseline photocurrent to determine a change in the optical transmission of the biochip, and communicate particle data to a remote device.

Abstract: Product offering systems are provided. Product offering systems may include sending an offer to a customer that possesses a mobile computing device and has agreed to receive offers for products via the mobile computing device. Agreeing to receive offers would result in the unique data about the customer being available to offer provider. Unique customer data may include data related to the customers wireless service provider or from a financial account in a financial institution, and collecting customer data about the customer, wherein the customer data comprises financial data and personal data. Product offering systems may further include registering a wireless computing device of the customer to able the device to receive the offer, and determining opportunities to send the offer to the customer by monitoring the customer and the customer data. Product offering systems may also include sending the offer to the customer's registered device based on the determination of opportunities.

Abstract: The oral cavity is an ideal-site for small molecule, nutrient and/or nutraceutical delivery to the systemic circulation due to the highly-vascularized, oral mucosa, near-neutral pH conditions, and avoidance of gastric and first-pass degradation. Accordingly, novel, saccharide-based, food-form, portable, individually wrapped, oral delivery systems that attach to these four, highly absorptive surfaces (e.g. gingival, buccal, soft palatal, sublingual) for a longer contact-duration than current orally available formulas resulting in greater, small molecule bioavailability, and a more rapid, therapeutic effect are preferred and described.

Abstract: Systems and methods are provided for interpreting a correlation model that predicts a correlation between a pair of data corresponding to a pair of incident tickets using an interpreter model. The correlation model includes a Siamese Network including a plurality of neural networks. The interpreter model, trained by using training data, represents a student model (a glass-box model) while the correlation model, trained using the training data, represents a more complex teacher model (a black-box mode) of a teacher-student model. The present disclosure generates global feature importance scores based on the trained interpreter model, which indicates a degree of influence of a feature compared to other features in incident data in determining correlations, to generate additional training data emphasizing influential features and to retrain the correlation model.

Abstract: Hemp-based absorbent articles are disclosed. The absorbent article can be a tampon or pad for feminine hygiene. The absorbent article can be flushable or compostable. In one example, the absorbent article is a flushable tampon for feminine hygiene having a nonwoven material comprising hemp with a hemp fiber length in a range of about 8 mm to about 15 mm. The nonwoven material can include an absorbent ribbon, a string, and an overwrap.

Abstract: An example of a memory device may comprise NAND media with a plurality of decks, and circuitry coupled to the NAND media to control access to a superblock of memory cells aligned along a pillar of the NAND media, wherein the superblock includes at least a first block that corresponds to memory cells aligned along the pillar in a first deck of the plurality of decks and a second block that corresponds to memory cells aligned along the pillar in a second deck of the plurality of decks, configure the NAND media in a first program mode for the first block of the superblock, and configure the NAND media in a second program mode for the second block of the superblock. Other examples are disclosed and claimed.

Abstract: The disclosed embodiments provide systems, methods, and techniques for managing merchandising cards. A merchandising card may be, for example, a gift card, loyalty card, or the like. Consistent disclosed embodiments, a system for managing merchandising cards may include one or more memory devices storing instructions and one or more processors configured to acquire, from a device over a network, a plurality of locations associated with the device, the device locations being acquired at different instances in time within a predetermined period of time. Additionally, the one or more processors may be configured to calculate an overall merchant confidence rating for a merchant using the device locations. Further, the one or more processors may be configured to, based on the overall merchant confidence rating, determine that the merchant matches a merchant that is associated with merchandising card, and send a reminder a user of the device.

Abstract: Millimeter wave access system and method for device-to-device communications (D2D) are described.

Abstract: A tourniquet for applying pressure to a limb to stop the flow of blood is disclosed. The tourniquet includes a plate, a first band and a second band. The first band draws through the plate. The first band includes a tensioning member. The second band positions within the first band such that one end of the second band connects to the first band and the other end of the second band connects to the tensioning member. The first band receives the limb of the user while the plate remains on the limb. The tensioning member operates to draw the second band towards the tensioning member allowing the first band to put pressure on the limb and stop the flow of blood. In one embodiment, the plate connects to a holster. Further, the plate suspends from a waist strap wrapped around a waist of the user.

Abstract: A base station central unit control plane (CU-CP) receives, from a base station central unit user plane (CU-UP), an indication of a size of downlink data for a wireless device. The base station CU-CP transmits, to a base station distributed unit (DU) and base on the size of the downlink data, a first paging message for the wireless device indicating a small data transmission (SDT) procedure of the wireless device.