Abstract: Compounds comprising R-G-Cysteic Acid (i.e., R-G-NH—CH(CH2—SO3H)COOH or Arg-Gly-NH—CH(CH2—SO3H)COOH) and derivatives thereof, including pharmaceutically acceptable salts, hydrates, stereoisomers, multimers, cyclic forms, linear forms, drug-conjugates, pro-drugs and their derivatives. Also disclosed are methods for making and using such compounds including methods for inhibiting integrins including but not necessarily limited to ?5?1-Integrin, ?v?3-Integrin and ?v?5-Integrin, inhibiting cellular adhesion to RGD binding sites, preventing or treating viral or other microbial infections, inhibiting angiogenesis in tumors, retinal tissue or other tissues or delivering other diagnostic or therapeutic agents to RGD binding sites in human or animal subjects.

Abstract: The disclosure describes artificial reality (AR) systems and techniques that enable hierarchical power management of multiple devices within a multi-device AR system. For example, a multi-device AR system includes a device comprising one of a peripheral device configured to generate artificial reality content for display or a head-mounted display unit (HMD) configured to output artificial reality content. The device comprises a System on a Chip (SoC) that includes a host subsystem and plurality of subsystems. Each subsystem includes a child energy processing unit configured to manage power states for the subsystem. The host subsystem includes a parent energy processing unit configured to direct power management of each of the child energy processing units of the plurality of subsystems.

Abstract: Methods, systems, and apparatus, including an apparatus for analyzing content that is displayed within an application (e.g., a native application) on a client device and making decisions regarding the presentation of content within the application. In one aspect, a process includes identifying an event occurring within the application. The event can be indicative of a display of content by the application. The content to be displayed is received from the application. Information representative of the content is sent to a server. A response is received from the server. The response is indicative of the suitability of the content for display within the application.

Abstract: A method of partitioning in video coding for JVET, comprising representing a JVET coding tree unit as a root node in a quadtree plus binary tree (QTBT structure that can have quadtree or binary partitioning of the root node and quadtree or binary trees branching from each of the leaf nodes. The partitioning at any depth can use asymmetric binary partitioning to split a child node represented by a leaf node into two child coding units of unequal size, representing the two child coding units as leaf nodes in a binary tree branching from the parent leaf node and coding the child coding units represented by final leaf nodes of the binary tree with JVET. Disclosed is a generalized method of partitioning a block, either square or rectangular, which leads to more flexible block sizes with possible higher coding efficiency.

Abstract: Embodiments of a targeted surface disinfection system are disclosed. The system includes a set of one or more UV lamps, a high voltage power supply for driving the lamps, a mobile carriage including a chassis supporting the set, an articulated head assembly including at least one UV lamp from the set, a vacuum pump, and a suction hose extending between the vacuum pump and the head assembly for dissipating heat generated by the at least one UV lamp. The system also includes a pulse configuration control unit for configuring an output of the high voltage power supply for driving the set to emit a UV radiant energy upon a target surface requiring disinfection, where the set of one or more UV lamps emits the UV radiant energy at a rate of at least 20 pulses per second.

Abstract: Techniques for implementing a pipeline system including a pipe fitting, which includes a fitting shell that define a fitting bore and a tubing cavity around the fitting bore. The tubing cavity interfaces with pipe segment tubing to facilitate fluidly coupling the fitting bore to a pipe bore. The fitting shell includes a seal groove that is recessed into a fitting shell surface that facilitates defining the tubing cavity. The pipe fitting includes a belt seal having a multisided axial cross-section profile, in which the belt seal is to be disposed in the seal groove to implement a fitting seal in the pipe fitting that includes a protruding portion having a wedge-shaped axial cross-section profile that protrudes beyond the fitting shell surface into the tubing cavity to facilitate sealing a fluid conduit implemented in an annulus of the pipe segment tubing in the tubing cavity of the pipe fitting.

Abstract: Embodiments relate to an audio system configured to provide enhancement of low audio frequencies. The audio system includes a tissue transducer and a speaker coupled to the tissue transducer. The tissue transducer is configured to be coupled to a tissue of a user (e.g., pinna of a user's ear). The speaker includes a diaphragm having a first surface and a second surface that is opposite the first surface. The first surface is configured to generate a first set of airborne acoustic pressure waves, and the second surface is configured to generate a backpressure. The tissue transducer is driven by the backpressure to vibrate the tissue to form a second set of acoustic pressure waves. The first set of airborne acoustic pressure waves and the second set of acoustic pressure waves together form audio content that is presented to the user.

Abstract: Aspects of the disclosure relate to assigning a fleet of driverless vehicles to a plurality of parking locations for parking vehicles of the fleet. For instance, locations of the vehicles of the fleet as well as a number of available spaces at each of the plurality of parking location locations may be tracked. A subset of the fleet not already located at one of the plurality of parking locations is identified. At least one assignment assigning each vehicle of the subset to a respective parking location of the plurality of parking locations is determined according to the numbers of available spaces and the identified locations of the subset. For the at least one assignment, a total cost is determined by determining a cost value for each of a plurality of factors. The given assignment is sent to the fleet based on the total cost and the cost value.

Abstract: Implementations relate to generating and/or executing a customized interactive dialog application. The customized interactive dialog application may be generated from a state mapping tool that allows a user to generate custom states and custom transitions between the custom states. A customized configuration description is then generated based on the generated custom states and custom transitions. Further, a default configuration description is identified that includes additional or alternative states and transitions. In executing the customized interactive dialog application, dialog turns are generated based on the states and transition information, with the customized configuration description taking precedence and the default configuration description being utilized for any undefined states and/or transitions. Implementations additionally or alternatively relate to generating and/or executing a custom agent based on generated custom states and custom transitions, and a default configuration description.

Abstract: The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention.

Abstract: A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel includes delivering at least a first fluid into the patient's blood vessel at a first flow rate, delivering at least a second fluid into the patient's blood vessel at a second flow rate, and adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

Abstract: A sensor rod assembly includes a master stick and an extension stick, where the master stick and the at least one extension stick are couplable together via at least one of a physical coupling, an electrical coupling, or a communicative coupling. The sensor rod assembly includes a controller with one or more processors, where the one or more processors are communicatively coupled to at least one set of detection circuitry and a user interface, where the one or more processors are configured to execute a set of program instructions configured to cause the one or more processors to receive one or more detection signals from at least one of the master stick or the extension stick and configured to cause the one or more processors to determine an elevation of a laser light based on the received one or more detection signals.

Abstract: Knowledge graphs can greatly improve the quality of content recommendation systems. There is a broad variety of knowledge graphs in the domain including clicked user-ad graphs, clicked query-ad graphs, keyword-display URL graphs etc. A hierarchical Transformer model learns entity embeddings in knowledge graphs. The model consists of two different Transformer blocks where the bottom block generates relation-dependent embeddings for the source entity and its neighbors, and the top block aggregates the outputs from the bottom block to produce the target entity embedding. To balance the information from contextual entities and the source entity itself, a masked entity model (MEM) task is combined with a link prediction task in model training.

Abstract: Disclosed are meeting spaces that are accessible through an adjoining facility or area, and associated systems and methods that provide automated levels of security for classified discussions. The meeting spaces are configured to automatically adapt to different levels of classification, e.g., from any of unclassified to top secret classifications. The meeting spaces are prevented from becoming active for their intended function until all required security features are activated. In some embodiments, the meeting spaces include one or more electronically opaquing privacy glass windows between the meeting space and the adjoining facility. The privacy glass can either appear as opaque, such as when a classified meeting or call is taking place or as a failsafe mode, or can be optically transmissive, such as when the space is unused, is used for unclassified purposes, and/or when the adjoining area is used at the same or higher level of classification.

Abstract: A system for forming a tendon sleeve on an atmospheric balloon is described herein, the system comprising a coupling assembly including a seam coupling mechanism that forms a seam joint between a first gore panel and a second gore panel, the seam joint is spaced from respective first and second lateral edges of the first and second gore panels to form first and second edge flanges, and an edge coupling mechanism that forms an edge joint between the first and second edge flanges and closes a tendon sleeve, the edge joint spaced from the seam joint, the tendon sleeve includes a tendon sleeve passage between the seam joint and the edge joint and between the first and second edge flanges. The system also includes a tendon positioning mechanism that positions a tendon within the tendon sleeve passage. A tendon sleeve formed by this system is also described herein.

Abstract: A vehicle includes a chassis, a plurality of tractive assemblies coupled to the chassis, and a controller. Each tractive assembly includes a tractive element and an actuator coupled to the tractive element and configured to move the tractive element relative to the chassis. The controller is configured to control at least one of the actuators to vary a load supported by one of the tractive assemblies in response to an indication that a portion of a first tractive assembly of the plurality of tractive assemblies is disabled.

Abstract: The present invention relates to polypeptide, preferably to a glucose isomerase, comprising an amino acid sequence, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, is at least 95% identical to an amino acid sequence of SEQ ID NO:1, wherein the amino acid sequence of the polypeptide, preferably the glucose isomerase, comprises an amino acid substitution at one or more amino acid positions, wherein the one or more amino acid positions is/are each and independently selected from the group consisting of SEQ ID NO: 1 amino acid positions 89, 90, 95, 0, 33, 34, 35, and 59. The present invention further relates to methods preparing glucose including the use of the polypeptides of the invention for preparing glucose.

Abstract: Disclosed herein are methods for collecting data from chip arrays and for piecewise real-time scanning and stitching of said data. Such arrays can comprise a plurality of microarrays, each microarray comprising biomolecular features that are attached to a surface of the microarray.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for detecting a continued conversation are disclosed. In one aspect, a method includes the actions of receiving first audio data of a first utterance. The actions further include obtaining a first transcription of the first utterance. The actions further include receiving second audio data of a second utterance. The actions further include obtaining a second transcription of the second utterance. The actions further include determining whether the second utterance includes a query directed to a query processing system based on analysis of the second transcription and the first transcription or a response to the first query. The actions further include configuring the data routing component to provide the second transcription of the second utterance to the query processing system as a second query or bypass routing the second transcription.

Abstract: In some examples, a method is disclosed. The method includes detecting, by a smart device, an audible utterance of a trigger word. The method also includes, responsive to the detection of the audible utterance of the trigger word, recording audio via the smart device. The method also includes processing, via the smart device, the recorded audio to determine whether the recorded audio contains a command for the smart device or a different smart device to perform an action. The method also includes, responsive to determining that the recorded audio includes a command for the smart device or a different smart device to perform the action, determining whether the command is serviceable by the smart device without involvement of the different smart device. The method also includes, responsive to determining whether the command is serviceable by the smart device without involvement of the different smart device, taking action regarding the command.