Abstract: Various embodiments provide a method of increasing immunity to a virus in a subject. The method can comprise administering to the subject one or more effective doses of an immune-enhancing natural-based composition; thereby stimulating increased expression one or more of IFN-?, IL-1B, IL-6, IL-10, IL-12p40, IL-12p70, and TNF-?; inhibiting replication of the virus inside a cell of the subject, and preventing entry of virus into the cell. The method of increasing immunity can further comprise increasing immunity to an upper respiratory tract viral infection. The upper respiratory tract viral infection can be COVID-19. According to some aspects of the method of increasing immunity, the effective dose of the immune-enhancing natural-based composition comprises: 30-70 mgs of cyanidin-3-glucosides; 40-80 mgs of andrographolides; 75-125 mgs of ascorbic acid; 400-600 mgs of beta glucans; 300-500 mgs of polysaccharides; and 75-125 mgs of a blend of antioxidants.
Type:
Application
Filed:
January 6, 2025
Publication date:
May 1, 2025
Applicant:
Plexus Worldwide, LLC
Inventors:
Michael Hartman, Lauren Knutsen, Michael Rogowski
Abstract: An illustrative dye sublimation apparatus (also referred to as a dye sublimation machine) may have at least four stations, each station implementing a discrete step of a sublimation cycle. Multiple beds are rotatably mounted such that the beds pass through the stations to perform the corresponding steps. Therefore, the sublimation apparatus may perform multiple sublimation cycles simultaneously with the beds containing printed sheets and substrates at different steps of the multiple sublimation cycles. As the beds are rotatably mounted, the sublimation apparatus may allow for a fixed loading and unloading station proximate to a fixed, dedicated personnel station.
Abstract: An axle assembly comprising a differential carrier, a differential assembly, a drive pinion, and a drive pinion brake. The drive pinion brake is mounted to the differential carrier. The differential carrier supports the differential assembly. The drive pinion brake is operable to apply a brake torque to inhibit rotation of the drive pinion.
Abstract: Provided herein are recombinant antibodies, antigen-binding fragments, and fusion proteins thereof useful for binding to and inhibiting programmed death 1 (PD-1), nucleic acid molecules encoding the same and therapeutic compositions thereof, as well as methods of using such antibodies, including the methods for enhancing T cell and NK cell function to increase cell and cytokine mediated immunity and methods of treatment of various immune dysfunction related disorders including cancer and infectious diseases.
Type:
Application
Filed:
December 20, 2024
Publication date:
May 1, 2025
Applicant:
Kadmon Corporation, LLC
Inventors:
Dan Lu, Zhanna Polonskaya, Tzu-Pei Chang, Stella Aviaty Martomo, Jeegar P. Patel, Faical Miyara
Abstract: A system for controlling a turbine is disclosed. The system includes a turbine control fuel governor that has a plurality of VCPIDs operating in parallel with one another. Each VCPID is associated with a respective turbine parameter and one or more external parameters. Each VCPID incorporates feedback from the parallel operating VCPIDs to feed an integral term of a current VCPID in the following manner: a previous derivative gain and a previous proportional gain are summed and subtracted from a selected output for the turbine to yield a result, and the result is input to an integral gain portion of the current VCPID.
Abstract: Methods and systems are described herein for minimizing development time in artificial intelligence models by automating model selection based on dataset fittings of time-series data prior to hyperparameter optimization. For example, the system may apply a profiling model using a time-series embedding of the dataset combined with the aggregate statistical profile. In either case, the profiling model may be trained on the scoring policy and/or a time-series embedding of the dataset combined with the aggregate statistical profile to determine a likelihood of the effectiveness of a given model on the given dataset and/or likely hyperparameters for the given model.
Abstract: Methods and systems are described herein for minimizing development time in artificial intelligence models by automating model selection based on dataset fittings of time-series data prior to hyperparameter optimization. The systems and methods described herein aim to reduce the redundancies and improve the efficiencies of model selection, model training, and/or hyperparameter selection. The systems and methods achieve this by using information about the attributes of the time-series dataset that may be used to determine a model that may be most effective at fitting a given dataset. If a model is selected prior to hyperparameter optimization, the time and resources spent training, fitting, and/or tuning models that are not selected can be avoided.
Abstract: A method for operating a transmitting device to communicate with a receiving device is described herein. The method includes the step of the transmitting device selecting a root index value from a set of root index values. The method further includes the step of the transmitting device generating a frequency domain Constant Amplitude Zero Auto-Correlation sequence based on the selected root index value. The method further includes the step of the transmitting device modulating the Constant Amplitude Zero Auto-Correlation sequence by a pseudo-noise sequence. The method further includes the step of the transmitting device generating an Orthogonal Frequency Division Multiplexing symbol, wherein the frequency domain Constant Amplitude Zero Auto-Correlation sequence modulated by the pseudo-noise sequence defines subcarrier values for the Orthogonal Frequency Division Multiplexing symbol.
Type:
Application
Filed:
November 25, 2024
Publication date:
May 1, 2025
Applicant:
ONE MEDIA, LLC
Inventors:
Kevin A. SHELBY, Michael J. SIMON, Mark EARNSHAW, Zahir Jaffer RAZA
Abstract: This disclosure describes systems, methods, and devices related to managing egress traffic from a network to one or more peer networks. A method may include generating, using a load balancer of a network, a dynamic logical egress traffic threshold for a peer network; determining, using the load balancer, that first traffic from the network to the peer network is below the logical egress traffic threshold; directing second traffic from the network to the peer network based on the determination that the first traffic is below the logical egress traffic threshold; determining, using the load balancer, that the second traffic from the network to the peer network has reached the logical egress traffic threshold; and directing third traffic from the network away from the peer network based on the determination that the second traffic has reached the logical egress traffic threshold.
Abstract: A system of properly displaying chroma key content is presented. The system obtains a digital representation of a 3D environment, for example a digital photo, and gathers data from that digital representation. The system renders the digital representation in an environmental model and displays that digital representation upon an output device. Depending upon the context, content anchors of the environmental model are selected which will be altered by suitable chroma key content. The chroma key content takes into consideration the position and orientation of the chroma key content relative to the content anchor and relative to the point of view that the environmental model is displayed from in order to accurately display chroma key content in a realistic manner.
Abstract: A system and method for selective activation and deactivation of electrical brushes used in a dynamoelectric machine for current density optimization is disclosed. The approach includes using an arrangement of switches electrically connected to the electrical brushes to selectively activate and deactivate the brushes during the operation of the dynamoelectric machine. This entails opening and closing selective ones of the switches for a predetermined time period to adjust the average current density of the electrical current passing through the electrical brushes to be within a predetermined current density range while the dynamoelectric machine is operating.
Type:
Application
Filed:
October 25, 2023
Publication date:
May 1, 2025
Applicant:
GE Infrastructure Technology LLC
Inventors:
Paul August Quail, Jason Salvatore Disanto, Eric Steven Buskirk
Abstract: A wireless device receives, from a base station, one or more radio resource control (RRC) messages indicating two-step random access resources of a two-step random access type. The wireless device transmits, while the two-step random access type and a four-step random access type are available for receiving a preamble a random access procedure and based on the two-step random access resources comprising contention-free two-step random access resources, a preamble via the contention-free two-step random access resources.
Abstract: A method and apparatus for traceably managing software throughout its life cycle is disclosed. In one embodiment, the method comprises accepting, in secure management service via a first client interface module of a set of client interface modules, a request from a member of a plurality of members of the software supply chain to sign designated information, the designated information associated with the secure software in at least one of the plurality of stages, signing the designated information in response to the request according to a private key of a key pair uniquely associated with the member, and providing the signed designated information to the member of the software supply chain.
Abstract: A pool system may include a plurality of devices of equipment distributed among an area and a pool automation controller that includes a shortrange wireless communication device configured to communicate with a first wireless communication device of a first device of equipment and a second wireless communication device of a second device of equipment. The pool automation controller may determine locations within the area of the first device and the second device with respect to the pool automation controller based at least in part on a first set of characteristics of a first wireless signal and a second set of characteristics of a second wireless signal.
Type:
Application
Filed:
October 30, 2024
Publication date:
May 1, 2025
Applicant:
Zodiac Pool Systems LLC
Inventors:
Minas Minassian, Jeremy Young, Darin Eames
Abstract: A device and system for and methods of using an ultrasound probe housing containing ultrasound probes configured to produce images inside the body of a patient for procedures requiring needle or probe insertion. The ultrasound probe housing can be configured with a guide channel cut-out or aperture between the ambient side and body side of a patient. A needle guide assembly may be pivotally connected internal to the guide channel cut-out or aperture of the ultrasound probe housing at a pivot point such that during use the needle enters the patient through the needle guide assembly within the ultrasonic probe housing so that the needle can be visualized by the ultrasonic probes in real time. The ultrasound probe housing may also provide an adhesion or suction quality to the body side of the device to facilitate aspects of the invention.
Type:
Application
Filed:
December 31, 2024
Publication date:
May 1, 2025
Applicant:
Dandelion Technologies, LLC
Inventors:
Paul ADAMS, Christopher VETTER, Michael Andrew HOLTMAN
Abstract: The present invention is directed to a new and novel articulating stylet medical device that facilitates endotracheal intubation. During an intubation procedure, the present device uniquely guides a distal portion of a standard, non-proprietary endotracheal tube (ETT) mounted thereover within the narrow confines of a patient's pharynx under visual control via a laryngoscope and then through the larynx and then in to the trachea. Thus, the articulating stylet of the present invention facilitates a faster and safer intubation procedures compared to prior art stylet medical devices.
Abstract: A system includes: an alternating current (AC) to direct current (DC) converter (AC-DC converter), the AC-DC converter connectable to a line voltage; and a DC to DC converter (DC-DC converter) connected to the AC-DC converter, the DC-DC converter including: a high voltage buck-boost converter having a secondary side connectable to a high voltage battery; a low voltage buck-boost converter having a secondary side connectable to a low voltage battery; and one or more transformers having a primary side connected to the AC-DC converter, a secondary side connected to a primary side of the high voltage buck-boost converter, and a tertiary side connected to a primary side of the low voltage buck-boost converter.
Type:
Application
Filed:
October 30, 2023
Publication date:
May 1, 2025
Applicant:
BorgWarner US Technologies LLC
Inventors:
Venkata Jaya Sai Praneeth Ammanamanchi, Alexandre M. S. Reis, Joseph A. Engel, Scott E. Bauer
Abstract: A crate includes a frame and first and second rod guides configured to be spaced along the frame. The first rod guide includes a first plurality of fingers, and the second rod guide comprises a second plurality of fingers. The first and second plurality of fingers are configured to be aligned with each other to define a first rod receiving slot between two adjacent fingers of the first plurality of fingers and a second rod receiving slot between two adjacent fingers of the second plurality of fingers. The first and second rod receiving slots are configured to accept a rod from a first side of the frame. A cribbing bar has a plurality of saddles, wherein a first saddle is aligned with the first and second rod receiving slots. A shaft extends through an aperture of the cribbing bar. A method of arranging a plurality of elongated rods is described.
Abstract: A blended furnish with improved performance characteristics while reducing environmental impact, when applied to a substrate and methods of making and using blended furnish are provided. A composite product using a blended furnish is also provided.
Type:
Application
Filed:
September 24, 2024
Publication date:
May 1, 2025
Applicant:
ARCLIN USA LLC
Inventors:
Samuel W. Lonberg, Matthew E. Tucker, Tiara E. O’Neal, Arun Narayan, Francis Loiseau, Mario Dupuis, Iordana Triantafillu