Patents Assigned to Ma'at
  • Cripto binding molecules
    Patent number: 8021661
    Abstract: The invention pertains to humanized forms of an anti-CRIPTO antibody and portions thereof. In one embodiment, the variable regions of these antibodies or polypeptides comprising them (e.g., full-length antibodies or domain deleted antibodies) can be used to treat disorders, such as cancer.
    Type: Grant
    Filed: July 3, 2007
    Date of Patent: September 20, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: Scott Glaser, Herman Van Vlijmen, Alexey Alexandrovich Lugovskoy, Michele Sanicola-Nadel, Xiufeng Wu, Ellen Garber, Jose William Saldanha
  • Truncated BAFF receptors
    Patent number: 8022182
    Abstract: The disclosure provides a non-naturally occurring BAFF-R glycoprotein having a deletion in the extracellular domain which results in an altered O-linked glycosylation pattern. The disclosure also provides methods and pharmaceutical compositions for treating B-cell- and T-cell-mediated disorders.
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: September 20, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: Christine Ambrose, Jeffrey Thompson, Yen-Ming Hsu, Dingyi Wen, Yaping Sun
  • Polyalkylene polymer compounds and uses thereof
    Patent number: 8017733
    Abstract: The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: September 13, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: KoChung Lin, R. Blake Pepinsky, Ling Ling Chen, Donna M. Hess, Edward Y. Lin, Russell C. Petter, Darren P. Baker
  • Cripto blocking antibodies and uses thereof
    Patent number: 8003763
    Abstract: The invention provides Cripto blocking antibodies, or biologically functional fragments thereof, and uses thereof. Antibodies which bind Cripto and modulate Cripto signaling are provided. Antibodies which bind Cripto and block the interaction between Cripto and ALK4 are provided. Antibodies which bind Cripto and modulate tumor growth are also provided. Antibodies which bind Cripto, modulate signaling, and modulate tumor growth are also provided. Antibodies which bind Cripto, block the interaction between Cripto and ALK4 and modulate tumor growth are provided. The invention also provides methods of using these antibodies in therapeutic, diagnostic, and research applications.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: August 23, 2011
    Assignee: Biogen IDEC MA Inc.
    Inventors: Michele Sanicola-Nadel, Kevin P. Williams, Susan Gail Schiffer, Paul Rayhorn
  • Structure and method for fabrication of field effect transistor gates with or without field plates
    Patent number: 8003504
    Abstract: A method for fabrication of a field effect transistor gate, with or without field plates, includes the steps of defining a relatively thin Schottky metal layer by a lithography/metal liftoff or metal deposition/etch process on a semiconductor surface. This is followed by depositing a dielectric passivation layer over the entire wafer and defining a second lithographic pattern coincident with or slightly inset from the boundaries of the previously defined metal gate layer. This is followed by etching the dielectric using dry or wet etching techniques and stripping the resist, followed by exposing and developing a third resist pattern to define the thicker gate metal layers required for electrical conductivity and also for the field plate if one is utilized. The final step is depositing gate and/or field plate metal, resulting in a gate electrode and an integral field plate.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: August 23, 2011
    Assignees: BAE Systems Information and Electronic Systems Integration Inc., Biogen IDEC MA Inc.
    Inventors: Anthony A. Immorlica, Pane-chane Chao, Kanin Chu
  • Two-stage cure polyimide oligomers
    Patent number: 7994274
    Abstract: A method for using citraconic anhydride and itaconic anhydride as addition cure end caps in reactions for forming polyamic acid oligomers and polyimide oligomers, is provided. Prepregs and high temperature adhesives made from the resulting oligomers, as well as, high temperature, low void volume composites made from the prepregs, are also provided.
    Type: Grant
    Filed: December 23, 2005
    Date of Patent: August 9, 2011
    Assignee: I.S.T. (MA) Corporation
    Inventors: Gary L. Deets, Jianming Xiong
  • Method for operating a lighting control console and lighting control console
    Patent number: 7995040
    Abstract: A method for operating a lighting control console for controlling a lighting system includes generating digital adjustment commands in the lighting control console. The digital adjustment commands are transmittable via data connections to lighting devices of the lighting system. The lighting control console includes at least one digital processor and at least one digital memory for generating, managing and storing the adjustment commands. The lighting control console further includes at least one display unit, and wherein graphical elements can be displayed graphically for the operator on the display unit. The display unit includes a touch-sensitive sensor surface, wherein touching the touch-sensitive sensor surface in the area of a contact surface on the display unit enables an operator input associated with each of these contact surfaces to be selected.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: August 9, 2011
    Assignee: MA Lighting Technology GmbH
    Inventor: Michael Adenau
  • ANTIBODIES TO VLA-1
    Publication number: 20110189177
    Abstract: Antibodies that specifically bind to VLA-1 integrin and methods of using these antibodies to treat immunological disorders in a subject. Also included are crystal structures of complexes formed by VLA-1 antibodies and their ligands, and VLA-1 antagonists and agonists identified by using the structure coordinates of these structures.
    Type: Application
    Filed: January 31, 2011
    Publication date: August 4, 2011
    Applicant: BIOGEN IDEC MA INC.
    Inventors: Michael Karpusas, Paul D. Lyne, Jose William Saldanha, Ellen A. Garber
  • Use of aqueous NaOH/thiourea solution in pilot-scale production of cellulose products
    Patent number: 7981337
    Abstract: The present invention relates to the use of an aqueous sodium hydroxide/thiourea solution, specifically to the use of an aqueous sodium hydroxide/thiourea solution for pilot-scale production of cellulose products, wherein sodium hydroxide constitutes 8.1%-12.0% of the total weight of the aqueous solution, thiourea constitutes 3.0%-6.0% of the total weight of the aqueous solution, and said cellulose products include regenerated cellulose filaments, films, nonwovens, as well as composite fibers and/or functional materials of protein/cellulose, chitin/cellulose, Konjac Glucomannan/cellulose, nano-crystal particle/cellulose, etc.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: July 19, 2011
    Assignees: Wuhan University, Jiangsu Long-Ma Green Fibers Co., Ltd.
    Inventors: Lina Zhang, Dong Ruan, Jinping Zhou, Ang Lv
  • Electronic dimmer circuit
    Patent number: 7982410
    Abstract: An electrical dimmer circuit comprising the electrical dimmer circuit for dimming the electrical power of a plurality of lighting means having at least one digital input channel, at which digital low-voltage input signals for specifying the light power of the various lighting means can be received, and having at least two output channels, on which output signals for dimming the electrical power of the respectively assigned lighting means can be output by pulse width modulation of a high alternating voltage.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: July 19, 2011
    Assignee: MA Lighting Technology GmbH
    Inventor: Michael Adenau
  • Methods of reducing chemotaxis using antibodies against monocyte chemotactic proteins
    Patent number: 7972597
    Abstract: The invention provides antibodies that bind to a plurality of ?-chemokines, particularly monocyte chemotactic proteins MCP-1, MCP-2 and MCP-3. The invention also provides cells producing the antibodies, and methods of making and using the same.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: July 5, 2011
    Assignee: Biogen Idec MA, Inc.
    Inventors: Antonin R. De Fougerolles, Victor E. Kotelianski, Carl Reid, Ellen Garber
  • Train-R: A Cysteine Rich Member of the TNF-Receptor Family
    Publication number: 20110158993
    Abstract: Novel receptor in the TNF family: TRAIN-receptor.
    Type: Application
    Filed: November 22, 2010
    Publication date: June 30, 2011
    Applicants: Biogen Idec MA Inc., Apoxis S.A.
    Inventors: Jurg Tschopp, Catherine Hession
  • Polynucleotides encoding members of the human B lymphocyte activation antigen B7 family and polypeptides encoded thereby
    Patent number: 7968680
    Abstract: The present invention provides novel isolated BLAA polynucleotides and the membrane-associated or secreted polypeptides encoded by the BLAA polynucleotides. Also provided are the antibodies that immunospecifically bind to a BLAA polypeptide or any derivative, variant, mutant or fragment of the BLAA polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the BLAA polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states, as well as to other uses.
    Type: Grant
    Filed: November 20, 2007
    Date of Patent: June 28, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: Cynthia Green, Victor Kotelianski, Antonin De Fougerolles, John Carulli, Catherine Hession
  • Automated System And Method For Monitoring Chromatography Column Performance, And Applications Thereof
    Publication number: 20110147312
    Abstract: The present invention provides automated systems and methods for monitoring column performance in process chromatography, and applications thereof. In an embodiment, column performance is monitored by generating a plurality of process values such as, for example, conductivity values or pH values with a detector during a chromatography step transition between a first mobile phase liquid and a second mobile phase liquid. The process values are transformed to form transformed process values in which noise present in the process values is suppressed. Column performance parameters are calculated based on the transformed process values and displayed during movement of the second mobile phase liquid through the chromatography column.
    Type: Application
    Filed: January 23, 2009
    Publication date: June 23, 2011
    Applicant: Biogen Idec MA Inc.
    Inventors: Paul Cunnien, Joydeep Ganguly, Basav Ghosh, Asif Ladiwala, Robert Song, Jorg Thommes
  • Indazole derivatives as modulators of interleukin-1 receptor-associated kinase
    Publication number: 20110152260
    Abstract: The present invention relates to modulators of IRAK kinases of formula (I) and provides compositions comprising such modulators, as well as methods therewith for treating IRAK-mediated or IRAK-associated conditions or diseases.
    Type: Application
    Filed: September 7, 2007
    Publication date: June 23, 2011
    Applicant: Biogen Idec Ma Inc.
    Inventors: Kevin Guckian, Charles Jewell, Patrick Conlon, Edward Yin Shiang Lin, Timothy Chan
  • Stabilized polypeptide compositions
    Patent number: 7960142
    Abstract: The invention is based, at least in part, on the development of stabilized binding molecules that consist of or comprise a stabilized scFv and methods for making such stabilized molecules.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: June 14, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: Scott Glaser, Stephen Demarest, Brian Robert Miller, William B. Snyder, Xiufeng Wu, Norman Wang, Lisa J. Croner, Alexey Alexandrovich Lugovskoy
  • Abutment post
    Patent number: D641877
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: July 19, 2011
    Assignee: Biotechnology Institute, I Mas D, S.L.
    Inventor: Eduardo Anitua Aldecoa
  • Angulated abutment
    Patent number: D641878
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: July 19, 2011
    Assignee: Biotechnology Institute, I Mas D, S.L.
    Inventor: Eduardo Anitua Aldecoa
  • Direct abutment
    Patent number: D642271
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: July 26, 2011
    Assignee: Biotechnology Institute, I Mas D, S.L.
    Inventor: Eduardo Anitua Aldecoa
  • Abutment
    Patent number: D642272
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: July 26, 2011
    Assignee: Biotechnology Institute, I Mas D, S.L.
    Inventor: Eduardo Anitua Aldecoa